| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N J Clauss, F P Mayer, W A Owens, M Vitela, K M Clarke, M A Bowman, R E Horton, D Gründemann, D Schmid, M Holy, G G Gould, W Koek, H H Sitte, L C Daw. Ethanol inhibits dopamine uptake via organic cation transporter 3: Implications for ethanol and cocaine co-abuse. Molecular psychiatry. 2023-06-12. PMID:37308680. |
ethanol inhibits dopamine uptake via organic cation transporter 3: implications for ethanol and cocaine co-abuse. |
2023-06-12 |
2023-08-14 |
mouse |
| N J Clauss, F P Mayer, W A Owens, M Vitela, K M Clarke, M A Bowman, R E Horton, D Gründemann, D Schmid, M Holy, G G Gould, W Koek, H H Sitte, L C Daw. Ethanol inhibits dopamine uptake via organic cation transporter 3: Implications for ethanol and cocaine co-abuse. Molecular psychiatry. 2023-06-12. PMID:37308680. |
cocaine increases extracellular monoamines by blocking dopamine (da), norepinephrine (ne) and serotonin (5-ht) transporters (dat, net and sert, respectively). |
2023-06-12 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
a multivariate regressor of patterned dopamine release predicts relapse to cocaine. |
2023-05-24 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
we reveal low-dimensional features of patterned dopamine release that are strong predictors of cue-induced reinstatement of cocaine seeking. |
2023-05-24 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
these findings provide important insights into the sufficiency of nac dopamine signaling dynamics-in interaction with sex-for recapitulating persistent cocaine seeking and future relapse vulnerability. |
2023-05-24 |
2023-08-14 |
mouse |
| Caleigh Curran, Farideh Davoudi, Gabriel Foster, Patrick Gorda. Refractory bradycardia and hypotension in patients with autonomic dysfunction treated with pseudoephedrine. BMJ case reports. vol 16. issue 4. 2023-05-16. PMID:37185313. |
we describe a man in his 40s with a history of chronic intranasal cocaine use and c5-c7 incomplete quadriplegia complicated by neurogenic orthostatic hypotension, admitted to the intensive care unit for worsening bradycardia and hypotension requiring initiation of dopamine and an increase of his home midodrine dose. |
2023-05-16 |
2023-08-14 |
Not clear |
| Aliaa Mousa, Muhammad Humayoun Rashid, Syeda Neelam Yamin Bukhari, Mohammad Abu-Abaa, Karan H Pahuj. Chronic Cocaine Abuse as a Cause of Sinus Bradycardia. Cureus. vol 15. issue 4. 2023-05-16. PMID:37193419. |
common cardiovascular manifestations of cocaine are related to its adrenergic effects due to the inhibition of dopamine and norepinephrine uptake at the postsynaptic terminal. |
2023-05-16 |
2023-08-14 |
Not clear |
| Lauren M Burgeno, Ryan D Farero, Nicole L Murray, Marios C Panayi, Jennifer S Steger, Marta E Soden, Scott B Evans, Stefan G Sandberg, Ingo Willuhn, Larry S Zweifel, Paul E M Phillip. Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine. bioRxiv : the preprint server for biology. 2023-04-24. PMID:37090565. |
cocaine seeking and taking are oppositely regulated by dopamine. |
2023-04-24 |
2023-08-14 |
Not clear |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine d2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. |
2023-04-22 |
2023-08-14 |
rat |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
to directly test this hypothesis, a cholinergic nicotinic receptor antagonist (mecamylamine; mec: 0, 10 or 30 µg/side) and a dopamine d2 receptor antagonist (l-741,626: 0, 0.63, 2.5 µg/side) were infused in the perirhinal cortex (prh) to block modulation of object recognition memory consolidation induced by 0.4 mg/kg nicotine, 20 mg/kg cocaine, or their css. |
2023-04-22 |
2023-08-14 |
rat |
| Ying S Chao, Jeffrey Parrilla-Carrero, Maya Eid, Oliver P Culver, Tyler B Jackson, Rachel Lipat, Makoto Taniguchi, Thomas C Jho. Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats. Cell reports. vol 42. issue 5. 2023-04-21. PMID:37083325. |
cocaine blocks dopamine reuptake, thereby producing rewarding effects that are widely studied. |
2023-04-21 |
2023-08-14 |
rat |
| Ying S Chao, Jeffrey Parrilla-Carrero, Maya Eid, Oliver P Culver, Tyler B Jackson, Rachel Lipat, Makoto Taniguchi, Thomas C Jho. Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats. Cell reports. vol 42. issue 5. 2023-04-21. PMID:37083325. |
however, cocaine also blocks serotonin uptake, which we show drives, in rats, individually variable aversive effects that depend on serotonin 2c receptors (5-ht2crs) in the rostromedial tegmental nucleus (rmtg), a major gabaergic afferent to midbrain dopamine neurons. |
2023-04-21 |
2023-08-14 |
rat |
| Maxwell Miller, Alisa Zezetko, Ritvij Satodiy. Development of Atypical Neuroleptic Malignant Syndrome After Treatment of Cocaine Intoxication: A Case Report and Literature Review. Cureus. vol 15. issue 2. 2023-04-03. PMID:37007397. |
although overlapping dopamine pathways between cocaine use and nms could deter one from this practice and guidelines recommend against it, antipsychotics are routinely used in the emergency setting for cocaine-associated agitation. |
2023-04-03 |
2023-08-14 |
Not clear |
| Mark D Namba, Megan N Phillips, Peng-Jen Chen, Benjamin E Blass, M Foster Olive, Janet L Neisewande. HIV gp120 impairs nucleus accumbens neuroimmune function and dopamine D3 receptor-mediated inhibition of cocaine seeking in male rats. Addiction neuroscience. vol 5. 2023-03-13. PMID:36909738. |
hiv gp120 impairs nucleus accumbens neuroimmune function and dopamine d3 receptor-mediated inhibition of cocaine seeking in male rats. |
2023-03-13 |
2023-08-14 |
human |
| Paul W Czoty, Aaron M Tryhus, Kiran K Solingapuram Sai, Susan H Nader, Phillip M Epperl. Association of dopamine D2-like and D Brain research. 2023-03-13. PMID:36914041. |
because of their importance in mediating the abuse-related effects of cocaine, brain dopamine receptors are logical candidates for investigation. |
2023-03-13 |
2023-08-14 |
Not clear |
| Brooke N Bender, Mary M Torregross. Intermittent cocaine self-administration has sex-specific effects on addiction-like behaviors in rats. Neuropharmacology. 2023-03-08. PMID:36889433. |
in subsets of rats, we evaluated: the ability of pavlovian cue extinction to reduce cue-induced drug seeking; motivation for cocaine using a progressive ratio procedure; punishment-resistant cocaine taking by pairing cocaine infusions with footshocks; and dependence of drug-seeking on dls dopamine (a measure of habit-like behavior) with the dopamine antagonist cis-flupenthixol. |
2023-03-08 |
2023-08-14 |
human |
| Kanako Matsumura, In Bae Choi, Meera Asokan, Nathan N Le, Luis Natividad, Lauren K Dobb. Striatal enkephalin supports maintenance of conditioned cocaine reward during extinction. bioRxiv : the preprint server for biology. 2023-03-03. PMID:36865224. |
we generated mice with a targeted deletion of enkephalin from dopamine d2-receptor expressing msns (d2-penkko) and tested them for cocaine cpp. |
2023-03-03 |
2023-08-14 |
mouse |
| Kristin Elfers, Laura Menne, Luca Colnaghi, Susanne Hoppe, Gemma Mazzuoli-Webe. Short- and Long-Term Effects of Cocaine on Enteric Neuronal Functions. Cells. vol 12. issue 4. 2023-02-25. PMID:36831246. |
the central mechanism through which cocaine initially leads to improved performance, followed by addictive behavior, has already been intensively studied and includes effects on the homeostasis of the neurotransmitters dopamine, partly mediated via nicotinic acetylcholine receptors, and serotonin. |
2023-02-25 |
2023-08-14 |
Not clear |
| Maciej M Jankowski, Bogna M Ignatowska-Jankowska, Wojciech Glac, Marek Wiergowski, Paulina Kazmierska-Grebowska, Artur H Swiergie. Intravenous haloperidol and cocaine alter the distribution of T CD3 Clinical and experimental pharmacology & physiology. 2023-02-21. PMID:36802086. |
intravenous haloperidol and cocaine alter the distribution of t cd3 the modulation of dopamine transmission evokes strong behavioral effects that can be achieved by commonly used psychoactive drugs such as haloperidol or cocaine. |
2023-02-21 |
2023-08-14 |
rat |
| Maciej M Jankowski, Bogna M Ignatowska-Jankowska, Wojciech Glac, Marek Wiergowski, Paulina Kazmierska-Grebowska, Artur H Swiergie. Intravenous haloperidol and cocaine alter the distribution of T CD3 Clinical and experimental pharmacology & physiology. 2023-02-21. PMID:36802086. |
cocaine non-specifically increases dopamine transmission by blocking dopamine active transporter (dat) and evokes behavioral arousal, while haloperidol is a non-specific d2-like dopamine receptor antagonist with sedative effects. |
2023-02-21 |
2023-08-14 |
rat |