| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Peris, S J Boyson, W A Cass, P Curella, L P Dwoskin, G Larson, L H Lin, R P Yasuda, N R Zahnise. Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. The Journal of pharmacology and experimental therapeutics. vol 253. issue 1. 1990-05-30. PMID:2329520. |
the purpose of this study was to test whether persistent changes consistent with behavioral sensitization occur in dopamine (da) uptake, release or receptors following repeated cocaine administration. |
1990-05-30 |
2023-08-11 |
rat |
| M J Kuhar, J W Boja, E J Con. Phencyclidine binding to striatal cocaine receptors. Neuropharmacology. vol 29. issue 3. 1990-05-24. PMID:2158002. |
pcp and related compounds inhibit 3h-mazindol binding to the cocaine receptor on dopamine transporters. |
1990-05-24 |
2023-08-11 |
Not clear |
| S L Peterson, S A Olsta, R T Matthew. Cocaine enhances medial prefrontal cortex neuron response to ventral tegmental area activation. Brain research bulletin. vol 24. issue 2. 1990-05-24. PMID:2322861. |
this study provides evidence that systemic but not microiontophoretic cocaine administration enhances dopamine receptor-mediated inhibitory vta input to a select population of mpfc efferent neurons. |
1990-05-24 |
2023-08-11 |
rat |
| L A Dolkart, M A Plessinger, J R Wood. Effect of alpha 1 receptor blockade upon maternal and fetal cardiovascular responses to cocaine. Obstetrics and gynecology. vol 75. issue 5. 1990-05-18. PMID:2158025. |
although cocaine produces uterine artery vasoconstriction primarily by alpha 1 adrenergic receptor stimulation, its vasoconstrictive effects may involve other vasoactive neurotransmitters, such as dopamine or serotonin. |
1990-05-18 |
2023-08-11 |
Not clear |
| C B Hubner, G F Koo. Bromocriptine produces decreases in cocaine self-administration in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 2. 1990-05-07. PMID:2317262. |
bromocriptine, a dopamine agonist, produced dose-dependent decreases in cocaine self-administration at doses of 4.0, 8.0, 16.0, and 32.0 mg/kg. |
1990-05-07 |
2023-08-11 |
rat |
| P Berger, J D Elsworth, M E Reith, D Tanen, R H Rot. Complex interaction of cocaine with the dopamine uptake carrier. European journal of pharmacology. vol 176. issue 2. 1990-04-26. PMID:2311671. |
complex interaction of cocaine with the dopamine uptake carrier. |
1990-04-26 |
2023-08-11 |
Not clear |
| Y L Hurd, F Weiss, G Koob, U Ungersted. The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen. Neuroscience letters. vol 109. issue 1-2. 1990-04-25. PMID:2314639. |
the influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen. |
1990-04-25 |
2023-08-11 |
rat |
| Y L Hurd, F Weiss, G Koob, U Ungersted. The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen. Neuroscience letters. vol 109. issue 1-2. 1990-04-25. PMID:2314639. |
presynaptic dopamine and acetylcholine transmission in the anteroventral (limbic) caudate-putamen were studied by microdialysis in freely moving rats during cocaine self-administration sessions. |
1990-04-25 |
2023-08-11 |
rat |
| Y L Hurd, F Weiss, G Koob, U Ungersted. The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen. Neuroscience letters. vol 109. issue 1-2. 1990-04-25. PMID:2314639. |
acute cocaine exposure elevated dopamine (da) overflow in drug-naive animals. |
1990-04-25 |
2023-08-11 |
rat |
| Y L Hurd, F Weiss, G Koob, U Ungersted. The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen. Neuroscience letters. vol 109. issue 1-2. 1990-04-25. PMID:2314639. |
the diminished dopamine response in repeatedly treated animals while self-administering cocaine was speculated to be due to increased activity of da transport carrier and/or supersensitive receptors modulating da release. |
1990-04-25 |
2023-08-11 |
rat |
| J W Boja, M J Kuha. [3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625137. |
[3h]cocaine binding and inhibition of [3h]dopamine uptake is similar in both the rat striatum and nucleus accumbens. |
1990-04-12 |
2023-08-11 |
rat |
| J W Boja, M J Kuha. [3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625137. |
cocaine binds with high affinity to the dopamine transporter in both the striatum and the nucleus accumbens. |
1990-04-12 |
2023-08-11 |
rat |
| J W Boja, M J Kuha. [3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625137. |
we examined na(+)-dependent [3h]cocaine binding, mazindol inhibition of [3h]cocaine binding and cocaine inhibition of [3h]dopamine uptake in both rat brain areas. |
1990-04-12 |
2023-08-11 |
rat |
| J W Boja, M J Kuha. [3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625137. |
likewise, cocaine inhibited [3h]dopamine uptake in both brain regions with equivalent efficacy. |
1990-04-12 |
2023-08-11 |
rat |
| M S Ahmed, D H Zhou, D Maulik, M E Eldefraw. Characterization of a cocaine binding protein in human placenta. Life sciences. vol 46. issue 8. 1990-04-06. PMID:2155365. |
the binding of this protein to norcocaine, pseudococaine, nomifensine, imipramine, desipramine, amphetamine and dopamine indicates that it shares some, but not all, the properties of the brain cocaine receptor. |
1990-04-06 |
2023-08-11 |
human |
| M C Ritz, E J Cone, M J Kuha. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life sciences. vol 46. issue 9. 1990-04-06. PMID:2308472. |
cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. |
1990-04-06 |
2023-08-11 |
Not clear |
| M C Ritz, E J Cone, M J Kuha. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life sciences. vol 46. issue 9. 1990-04-06. PMID:2308472. |
structure-activity relationships for cocaine and analog binding at the dopamine, norepinephrine and serotonin transporters were determined. |
1990-04-06 |
2023-08-11 |
Not clear |
| M C Ritz, E J Cone, M J Kuha. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life sciences. vol 46. issue 9. 1990-04-06. PMID:2308472. |
in general, our results indicate that unique structural requirements exist for each transporter site, but that cocaine binding at norepinephrine and dopamine transporters can be described by more similar structure-activity relationships than those found for the serotonin transporter. |
1990-04-06 |
2023-08-11 |
Not clear |
| M C Ritz, E J Cone, M J Kuha. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life sciences. vol 46. issue 9. 1990-04-06. PMID:2308472. |
requirements for cocaine binding to the dopamine transporter, which we have previously shown to be associated with the reinforcing effects of cocaine, include levorotatory stereospecificity, the benzene ring at c3, at least some portions of the tropane ring, and the presence of the c2 methyl ester group in the beta conformation. |
1990-04-06 |
2023-08-11 |
Not clear |
| K A Cunningham, J M Lakosk. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 1. 1990-04-05. PMID:2137698. |
a selective inhibitor of uptake for 5-ht (fluoxetine; id50 = 1.8 +/- 0.5 mg/kg), but not norepinephrine (desipramine) or dopamine (gbr 12909), mimicked cocaine, as did the monoamine releaser amphetamine (id50 = 2.86 +/- 0.46 mg/kg). |
1990-04-05 |
2023-08-11 |
rat |