| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J D Stekete. Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: behavioral and in vivo microdialysis studies. Neuropharmacology. vol 32. issue 12. 1994-05-10. PMID:8152520. |
injection of the protein kinase inhibitor h7 into the a10 dopamine region blocks the acute responses to cocaine: behavioral and in vivo microdialysis studies. |
1994-05-10 |
2023-08-12 |
Not clear |
| D D Wheeler, A M Edwards, B M Chapman, J G Ond. Effects of cocaine on sodium dependent dopamine uptake in rat striatal synaptosomes. Neurochemical research. vol 19. issue 1. 1994-04-26. PMID:8139762. |
effects of cocaine on sodium dependent dopamine uptake in rat striatal synaptosomes. |
1994-04-26 |
2023-08-12 |
rat |
| D D Wheeler, A M Edwards, B M Chapman, J G Ond. Effects of cocaine on sodium dependent dopamine uptake in rat striatal synaptosomes. Neurochemical research. vol 19. issue 1. 1994-04-26. PMID:8139762. |
initial velocity of uptake of dopamine (da) has been measured in the presence of 1 microm cocaine as a function of both [da] and [na]. |
1994-04-26 |
2023-08-12 |
rat |
| H F Luoh, T B Kuo, S H Chan, W H Pa. Power spectral analysis of electroencephalographic desynchronization induced by cocaine in rats: correlation with microdialysis evaluation of dopaminergic neurotransmission at the medial prefrontal cortex. Synapse (New York, N.Y.). vol 16. issue 1. 1994-04-19. PMID:8134898. |
samples collected by in vivo microdialysis at the medial prefrontal cortex (mpfc) and analyzed by hplc showed that the elevation of cocaine and dopamine (da) level in the dialysate reached its peak during the time interval when maximal activation of eeg occurred. |
1994-04-19 |
2023-08-12 |
rat |
| D E Weese-Mayer, J M Silvestri, D Lin, C M Buhrfiend, E S Lo, P M Carve. Effect of cocaine in early gestation on striatal dopamine and neurotrophic activity. Pediatric research. vol 34. issue 3. 1994-04-18. PMID:8134184. |
effect of cocaine in early gestation on striatal dopamine and neurotrophic activity. |
1994-04-18 |
2023-08-12 |
human |
| D E Weese-Mayer, J M Silvestri, D Lin, C M Buhrfiend, E S Lo, P M Carve. Effect of cocaine in early gestation on striatal dopamine and neurotrophic activity. Pediatric research. vol 34. issue 3. 1994-04-18. PMID:8134184. |
prenatal exposure to the dopamine (da) agonist cocaine, even if limited to early gestation, is associated with impaired developmental outcome in the human infant. |
1994-04-18 |
2023-08-12 |
human |
| D E Weese-Mayer, J M Silvestri, D Lin, C M Buhrfiend, E S Lo, P M Carve. Effect of cocaine in early gestation on striatal dopamine and neurotrophic activity. Pediatric research. vol 34. issue 3. 1994-04-18. PMID:8134184. |
cocaine exposure reduced striatal dopamine by 46% (t = 2.31; p < 0.05) and striatal 3,4-dihydroxyphenyl acetic acid by 49% (t = 2.44; p < 0.05). |
1994-04-18 |
2023-08-12 |
human |
| R W Keller, I M Maisonneuve, D M Nuccio, J N Carlson, S D Glic. Effects of prenatal cocaine exposure on the nigrostriatal dopamine system: an in vivo microdialysis study in the rat. Brain research. vol 634. issue 2. 1994-04-15. PMID:8131076. |
offspring were examined by microdialysis between postnatal days 10-125 to study the effects of prenatal cocaine exposure on the nigrostriatal dopamine (da) system. |
1994-04-15 |
2023-08-12 |
rat |
| P Jatlo. Cocaethylene: pharmacologic activity and clinical significance. Therapeutic drug monitoring. vol 15. issue 6. 1994-04-07. PMID:8122289. |
however, cocaine and cocaethylene also appear to differ in some respects, including the relative potency of their actions on the dopamine and serotonin transporters. |
1994-04-07 |
2023-08-12 |
human |
| T Brücke, J Kornhuber, P Angelberger, S Asenbaum, H Frassine, I Podrek. SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT. Binding kinetics in the human brain. Journal of neural transmission. General section. vol 94. issue 2. 1994-03-31. PMID:8110440. |
single photon emission computerized tomography (spect) studies in non-human primates have previously shown that the cocaine derivative [123i]-2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane ([123i]beta-cit) labels dopamine transporters in the striatum and serotonin transporters in the hypothalamus-midbrain area. |
1994-03-31 |
2023-08-12 |
human |
| S J Gatley, D W Yu, J S Fowler, R R MacGregor, D J Schlyer, S L Dewey, A P Wolf, T Martin, C E Shea, N D Volko. Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain. Journal of neurochemistry. vol 62. issue 3. 1994-03-28. PMID:8113802. |
in vitro assays with rat brain membranes showed that cocaine and 4'-fluorococaine were equipotent at the dopamine reuptake site, but that 4'-fluorococaine was about 100 times more potent at the 5-hydroxytryptamine reuptake site. |
1994-03-28 |
2023-08-12 |
rat |
| I M Maisonneuve, M J Kree. Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study. The Journal of pharmacology and experimental therapeutics. vol 268. issue 2. 1994-03-28. PMID:8114005. |
acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study. |
1994-03-28 |
2023-08-12 |
human |
| I M Maisonneuve, M J Kree. Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study. The Journal of pharmacology and experimental therapeutics. vol 268. issue 2. 1994-03-28. PMID:8114005. |
to address a growing concern about the relevance of the pattern of cocaine administration used in animal studies, the aim of the present work was to establish the dopamine (da) response of an acute cocaine "binge" that attempts to parallel as closely as possible the human drug abuse pattern. |
1994-03-28 |
2023-08-12 |
human |
| K Y Little, J A Kirkman, F I Carroll, T B Clark, G E Dunca. Cocaine use increases [3H]WIN 35428 binding sites in human striatum. Brain research. vol 628. issue 1-2. 1994-03-23. PMID:8313144. |
animal studies suggest that chronic cocaine exposure may increase the function and/or synthesis of the dopamine transporter (dat) under certain conditions, but the literature is complex. |
1994-03-23 |
2023-08-12 |
human |
| S Kitayama, J B Wang, G R Uh. Dopamine transporter mutants selectively enhance MPP+ transport. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310426. |
to help define selective molecular mechanisms by which mpp+ uptake occurs, we have tested dopamine transporters mutated in several residues for their abilities to accumulate dopamine and mpp+, and to bind a cocaine analog. |
1994-03-17 |
2023-08-12 |
Not clear |
| S Kitayama, J B Wang, G R Uh. Dopamine transporter mutants selectively enhance MPP+ transport. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310426. |
these mutations exert much more modest effects on dopamine uptake and have little impact on cocaine analog binding. |
1994-03-17 |
2023-08-12 |
Not clear |
| A L Brownell, P Hantraye, U Wullner, L Hamberg, T Shoup, D R Elmaleh, D M Frim, B K Madras, G L Brownell, B R Rose. PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates. Experimental neurology. vol 125. issue 1. 1994-03-16. PMID:7905836. |
dopamine reuptake sites and fibers assessed by the 11c-labeled cocaine analog, win 35 428 compound, and pet showed a temporary decrease in areas with mild neuronal loss and a long-term decrease in striatal regions with severe destruction. |
1994-03-16 |
2023-08-12 |
monkey |
| P A Broderic. In vivo electrochemical studies of gradient effects of (SC) cocaine on dopamine and serotonin release in dorsal striatum of conscious rats. Pharmacology, biochemistry, and behavior. vol 46. issue 4. 1994-03-15. PMID:8309978. |
in vivo electrochemical studies of gradient effects of (sc) cocaine on dopamine and serotonin release in dorsal striatum of conscious rats. |
1994-03-15 |
2023-08-12 |
rat |
| P A Broderic. In vivo electrochemical studies of gradient effects of (SC) cocaine on dopamine and serotonin release in dorsal striatum of conscious rats. Pharmacology, biochemistry, and behavior. vol 46. issue 4. 1994-03-15. PMID:8309978. |
(sc) cocaine was studied for its influence on in vivo dopamine (da) and serotonin (5-ht) release in dorsal striatum (str), with a further study of an anterior-posterior dorsal subdivision in a range of +/- 400 microns. |
1994-03-15 |
2023-08-12 |
rat |
| D French, J M Witki. Effects of the dopamine release inhibitor, CGS 10746B, on the locomotor stimulant and discriminative stimulus effects of cocaine and methamphetamine. Pharmacology, biochemistry, and behavior. vol 46. issue 4. 1994-03-15. PMID:8309980. |
effects of the dopamine release inhibitor, cgs 10746b, on the locomotor stimulant and discriminative stimulus effects of cocaine and methamphetamine. |
1994-03-15 |
2023-08-12 |
mouse |