| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Lyons, L J Porrin. Dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. Brain research. vol 753. issue 1. 1997-07-17. PMID:9125433. |
thus, the present study describes functional evidence of the link between the rostral accumbens and the extended amygdala and demonstrates that dopamine in the rostral accumbens plays an important role in the central response to cocaine. |
1997-07-17 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
in the first experiment, the effect of cocaine injections on vp dopamine was examined by microdialysis. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
injections of cocaine 5-20 mg/kg dose-dependently increased the extracellular dopamine level in vp 2.5-4.5-fold. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
in addition, intra-vp perfusion of 20 microm cocaine induced a 12-fold increase of dopamine locally. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
however, rats with more than 60% depletion in vp dopamine did not develop cpp to cocaine at either dose. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
it was concluded that vp dopamine may play a critical role in the initial rewarding effect of cocaine. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
dopamine concentration in vp did not correlate with the locomotor activation response to cocaine at either dose. |
1997-07-15 |
2023-08-12 |
rat |
| N H Chen, Y L Wang, M E Reit. Binding of the [125I]3 beta-(iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester to the dopamine transporter at a physiologically relevant temperature: mutually exclusive binding and different ionic requirements for various uptake blockers and substrates. Synapse (New York, N.Y.). vol 25. issue 2. 1997-07-07. PMID:9021896. |
the present study describes the binding of cocaine analog [125i]3 beta-(iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester ([125i]rti-121), a highly selective ligand for the dopamine transporter (dat), to rat striatal synaptosomal membranes at 37 degrees c. saturation analysis of [125i]rti-121 binding revealed a single binding site with similar affinity for rti-121 at both 50 and 134 mm nacl. |
1997-07-07 |
2023-08-12 |
rat |
| N H Chen, Y L Wang, M E Reit. Binding of the [125I]3 beta-(iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester to the dopamine transporter at a physiologically relevant temperature: mutually exclusive binding and different ionic requirements for various uptake blockers and substrates. Synapse (New York, N.Y.). vol 25. issue 2. 1997-07-07. PMID:9021896. |
at 134 mm nacl, the copresence of gbr12935, btcp, cocaine, amphetamine, or dopamine decreased the affinity of rti-121 to the extent predicted by a model in which the binding of all compounds is mutually exclusive. |
1997-07-07 |
2023-08-12 |
rat |
| J W Tidey, K A Micze. Acquisition of cocaine self-administration after social stress: role of accumbens dopamine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151353. |
acquisition of cocaine self-administration after social stress: role of accumbens dopamine. |
1997-07-07 |
2023-08-12 |
rat |
| M S Matell, G R Kin. 5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151358. |
5-ht3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. |
1997-07-07 |
2023-08-12 |
rat |
| M S Matell, G R Kin. 5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151358. |
the present experiment examined changes in the ability of the selective 5-ht3 receptor agonist, 1-(m-chlorophenyl)-biguanide (mcpbg), to facilitate k(+)-induced dopamine (da) release during withdrawal from continuous cocaine administration. |
1997-07-07 |
2023-08-12 |
rat |
| S H Yen, C J Lai, J Y Lin, J T Pa. Inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. Brain research bulletin. vol 42. issue 5. 1997-07-01. PMID:9092875. |
inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. |
1997-07-01 |
2023-08-12 |
rat |
| C E Maggos, R Spangler, Y Zhou, S D Schlussman, A Ho, M J Kree. Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. Synapse (New York, N.Y.). vol 26. issue 1. 1997-06-27. PMID:9097405. |
quantitation of dopamine transporter mrna in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. |
1997-06-27 |
2023-08-12 |
rat |
| C E Maggos, R Spangler, Y Zhou, S D Schlussman, A Ho, M J Kree. Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. Synapse (New York, N.Y.). vol 26. issue 1. 1997-06-27. PMID:9097405. |
as cocaine binds to and inhibits the activity of the dopamine transporter, we sought to determine if there were differences in dopamine transporter mrna levels between saline- and cocaine-injected rats or rats withdrawn from a chronic "binge" pattern (15 mg/kg per dose i.p. |
1997-06-27 |
2023-08-12 |
rat |
| A K Lienau, K Kuschinsk. Sensitization phenomena after repeated administration of cocaine or D-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 4. 1997-06-27. PMID:9109371. |
sensitization phenomena after repeated administration of cocaine or d-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. |
1997-06-27 |
2023-08-12 |
rat |
| A K Lienau, K Kuschinsk. Sensitization phenomena after repeated administration of cocaine or D-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 4. 1997-06-27. PMID:9109371. |
estimation of the extracellular dopamine using microdialysis in the striatum showed no significant differences between the three cocaine groups in the moderate increases. |
1997-06-27 |
2023-08-12 |
rat |
| V P Dhopesh, P M Yagnik, W W Weddingto. Can cocaine abuse cause parkinsonism? The American journal on addictions. vol 6. issue 2. 1997-06-25. PMID:9134080. |
dopamine deficiency is found in both chronic cocaine abusers and parkinson's disease. |
1997-06-25 |
2023-08-12 |
human |
| D C Mas. Are neuroadaptations in D3 dopamine receptors linked to the development of cocaine dependence? Molecular psychiatry. vol 2. issue 1. 1997-06-25. PMID:9154209. |
are neuroadaptations in d3 dopamine receptors linked to the development of cocaine dependence? |
1997-06-25 |
2023-08-12 |
Not clear |
| D E Comings, R Gade, S Wu, C Chiu, G Dietz, D Muhleman, G Saucier, L Ferry, R J Rosenthal, H R Lesieur, L J Rugle, P MacMurra. Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors. Molecular psychiatry. vol 2. issue 1. 1997-06-25. PMID:9154217. |
recent studies by self and coworkers have suggested an important interaction between the dopamine d1 and d2 receptors in cocaine abuse. |
1997-06-25 |
2023-08-12 |
human |