| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D M Wilson, A P Ferko, E J Barbieri, G J DiGregorio, E Bobyock, R McMichae. The interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164556. |
the interactions between dopamine, cocaine, cocaethylene, and ethanol were studied in swiss-webster mice. |
1997-07-30 |
2023-08-12 |
mouse |
| D M Wilson, A P Ferko, E J Barbieri, G J DiGregorio, E Bobyock, R McMichae. The interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164556. |
immediately upon regaining of the righting reflex, mice were injected intracerebroventricularly (icv) with saline, dopamine (0.1, 0.5, or 1.0 mumol/kg), cocaine (1, 15, or 25 mumol/kg), or cocaethylene (1, 15, or 25 mumol/kg). |
1997-07-30 |
2023-08-12 |
mouse |
| D M Wilson, A P Ferko, E J Barbieri, G J DiGregorio, E Bobyock, R McMichae. The interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164556. |
the results of this study showed that the neurotransmitter dopamine and both cocaine and cocaethylene can promote further cns depression in the presence of systemic ethanol, and that dopamine was significantly more potent than cocaine and cocaethylene as measured by the return to the lorr. |
1997-07-30 |
2023-08-12 |
mouse |
| S L Dewey, C S Chaurasia, C E Chen, N D Volkow, F A Clarkson, S P Porter, R M Straughter-Moore, D L Alexoff, D Tedeschi, N B Russo, J S Fowler, J D Brodi. GABAergic attenuation of cocaine-induced dopamine release and locomotor activity. Synapse (New York, N.Y.). vol 25. issue 4. 1997-07-24. PMID:9097399. |
using in vivo microdialysis techniques we examined this modulatory role and the extent to which three different gabaergic drugs can attenuate cocaine's ability to increase extracellular dopamine concentrations and gross locomotor activity. |
1997-07-24 |
2023-08-12 |
Not clear |
| M E Reith, C Xu, N H Che. Pharmacology and regulation of the neuronal dopamine transporter. European journal of pharmacology. vol 324. issue 1. 1997-07-24. PMID:9137907. |
dopamine and blockers of uptake such as cocaine probably bind to both shared and separate domains on the transporter, which can be influenced dramatically by the presence of cations. |
1997-07-24 |
2023-08-12 |
Not clear |
| P M Callahan, K A Cunningha. Modulation of the discriminative stimulus properties of cocaine: comparison of the effects of fluoxetine with 5-HT1A and 5-HT1B receptor agonists. Neuropharmacology. vol 36. issue 3. 1997-07-24. PMID:9175616. |
the ability of buspirone, but not gepirone, to attenuate the cocaine stimulus probably reflects its dopamine (da) d2 receptor antagonist properties and not its efficacy at 5-ht1a receptors. |
1997-07-24 |
2023-08-12 |
rat |
| C P Silvia, M Jaber, G R King, E H Ellinwood, M G Caro. Cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135047. |
cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides. |
1997-07-21 |
2023-08-12 |
rat |
| C P Silvia, M Jaber, G R King, E H Ellinwood, M G Caro. Cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135047. |
we have developed an antisense oligodeoxynucleotide to the dopamine transporter and used it to discriminate the behavioral properties of amphetamine and cocaine. |
1997-07-21 |
2023-08-12 |
rat |
| C P Silvia, M Jaber, G R King, E H Ellinwood, M G Caro. Cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135047. |
using various psychostimulants that target the dopamine transporter and increase dopamine levels, we found that the antisense-treated animals consistently rotated contralaterally in response to amphetamine (2 mg/kg), but not to cocaine (10 mg/kg) or nomifensine (10 mg/kg). |
1997-07-21 |
2023-08-12 |
rat |
| C P Silvia, M Jaber, G R King, E H Ellinwood, M G Caro. Cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135047. |
these results bring in vivo evidence for a different mode of action of amphetamine and cocaine on the dopamine transporter and lend direct support to the view that amphetamine acts as a dopamine releaser, whereas cocaine acts by blocking dopamine transport. |
1997-07-21 |
2023-08-12 |
rat |
| M J Nirenberg, J Chan, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 14. 1997-07-21. PMID:9204909. |
dat is also a major binding site for cocaine and other stimulants, the psychoactive effects of which are associated primarily with the inhibition of dopamine reuptake within mesocorticolimbic dopaminergic neurons. |
1997-07-21 |
2023-08-12 |
rat |
| M J Nirenberg, J Chan, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 14. 1997-07-21. PMID:9204909. |
these findings suggest that intermediate and distal dendrites are both the primary sites of dopamine reuptake and the principal targets of cocaine and related psychostimulants within dopaminergic neurons in the vta. |
1997-07-21 |
2023-08-12 |
rat |
| S J Boyson, C E Adam. D1 and D2 dopamine receptors in perinatal and adult basal ganglia. Pediatric research. vol 41. issue 6. 1997-07-18. PMID:9167195. |
cocaine acts as a stimulant of dopamine receptors and may cause long-term abnormalities in children exposed in utero. |
1997-07-18 |
2023-08-12 |
human |
| D Lyons, L J Porrin. Dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. Brain research. vol 753. issue 1. 1997-07-17. PMID:9125433. |
dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. |
1997-07-17 |
2023-08-12 |
rat |
| D Lyons, L J Porrin. Dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. Brain research. vol 753. issue 1. 1997-07-17. PMID:9125433. |
thus, the present study describes functional evidence of the link between the rostral accumbens and the extended amygdala and demonstrates that dopamine in the rostral accumbens plays an important role in the central response to cocaine. |
1997-07-17 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
in the first experiment, the effect of cocaine injections on vp dopamine was examined by microdialysis. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
injections of cocaine 5-20 mg/kg dose-dependently increased the extracellular dopamine level in vp 2.5-4.5-fold. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
in addition, intra-vp perfusion of 20 microm cocaine induced a 12-fold increase of dopamine locally. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
however, rats with more than 60% depletion in vp dopamine did not develop cpp to cocaine at either dose. |
1997-07-15 |
2023-08-12 |
rat |
| W Gong, D Neill, J B Justic. 6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134965. |
it was concluded that vp dopamine may play a critical role in the initial rewarding effect of cocaine. |
1997-07-15 |
2023-08-12 |
rat |