Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S H Yen, C J Lai, J Y Lin, J T Pa. Inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. Brain research bulletin. vol 42. issue 5. 1997-07-01. PMID:9092875. |
inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. |
1997-07-01 |
2023-08-12 |
rat |
C E Maggos, R Spangler, Y Zhou, S D Schlussman, A Ho, M J Kree. Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. Synapse (New York, N.Y.). vol 26. issue 1. 1997-06-27. PMID:9097405. |
quantitation of dopamine transporter mrna in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. |
1997-06-27 |
2023-08-12 |
rat |
C E Maggos, R Spangler, Y Zhou, S D Schlussman, A Ho, M J Kree. Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal. Synapse (New York, N.Y.). vol 26. issue 1. 1997-06-27. PMID:9097405. |
as cocaine binds to and inhibits the activity of the dopamine transporter, we sought to determine if there were differences in dopamine transporter mrna levels between saline- and cocaine-injected rats or rats withdrawn from a chronic "binge" pattern (15 mg/kg per dose i.p. |
1997-06-27 |
2023-08-12 |
rat |
A K Lienau, K Kuschinsk. Sensitization phenomena after repeated administration of cocaine or D-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 4. 1997-06-27. PMID:9109371. |
sensitization phenomena after repeated administration of cocaine or d-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. |
1997-06-27 |
2023-08-12 |
rat |
A K Lienau, K Kuschinsk. Sensitization phenomena after repeated administration of cocaine or D-amphetamine in rats: associative and non-associative mechanisms and the role of dopamine in the striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 4. 1997-06-27. PMID:9109371. |
estimation of the extracellular dopamine using microdialysis in the striatum showed no significant differences between the three cocaine groups in the moderate increases. |
1997-06-27 |
2023-08-12 |
rat |
V P Dhopesh, P M Yagnik, W W Weddingto. Can cocaine abuse cause parkinsonism? The American journal on addictions. vol 6. issue 2. 1997-06-25. PMID:9134080. |
dopamine deficiency is found in both chronic cocaine abusers and parkinson's disease. |
1997-06-25 |
2023-08-12 |
human |
D C Mas. Are neuroadaptations in D3 dopamine receptors linked to the development of cocaine dependence? Molecular psychiatry. vol 2. issue 1. 1997-06-25. PMID:9154209. |
are neuroadaptations in d3 dopamine receptors linked to the development of cocaine dependence? |
1997-06-25 |
2023-08-12 |
Not clear |
D E Comings, R Gade, S Wu, C Chiu, G Dietz, D Muhleman, G Saucier, L Ferry, R J Rosenthal, H R Lesieur, L J Rugle, P MacMurra. Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors. Molecular psychiatry. vol 2. issue 1. 1997-06-25. PMID:9154217. |
recent studies by self and coworkers have suggested an important interaction between the dopamine d1 and d2 receptors in cocaine abuse. |
1997-06-25 |
2023-08-12 |
human |
K Tatsch, J Schwarz, P D Mozley, R Linke, O Pogarell, W H Oertel, R S Fieber, K Hahn, H F Kun. Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [123I]IPT and single-photon emission tomography. European journal of nuclear medicine. vol 24. issue 4. 1997-06-24. PMID:9096093. |
ipt [n-(3-iodopropen-2-yl)- 2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane] is a new cocaine analogue which allows the presynaptic dopamine transporters to be imaged with single-photon emission tomography (spet) as early as 1-2 h post injection. |
1997-06-24 |
2023-08-12 |
Not clear |
M C Ritz, F R Georg. Cocaine toxicity: concurrent influence of dopaminergic, muscarinic and sigma receptors in mediating cocaine-induced lethality. Psychopharmacology. vol 129. issue 4. 1997-06-19. PMID:9085400. |
the dopamine reuptake inhibitor bupropion increased the number of occurrences of lethality produced by (-) cocaine, while the dopaminergic d1 antagonist sch 23390, the muscarinic m1 antagonist pirenzepine, and the sigma ligand (+) skf 10047 all significantly, but only partially, antagonized (-) cocaine-induced lethality. |
1997-06-19 |
2023-08-12 |
mouse |
W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
the present study investigated one of the functional aspects of dopaminergic system in neonatal rats exposed prenatally to a binge-like alcohol paradigm by measuring dopamine concentrations following a single postnatal cocaine challenge. |
1997-06-19 |
2023-08-12 |
rat |
W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
basal dopamine levels (0 mg/kg cocaine group) did not alter as a function of prenatal alcohol treatment in either region. |
1997-06-19 |
2023-08-12 |
rat |
W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
however, acute cocaine injection increased the dopamine content in nac, but not in sn/vta, in ad lib-fed animals, and this elevation in dopamine level was significantly attenuated by prenatal alcohol treatment in both female and male animals, and by prenatal pair-fed treatment in male animals. |
1997-06-19 |
2023-08-12 |
rat |
H Nakamura, T Hishinuma, Y Tomioka, S Ishiwata, T Ido, R Iwata, Y Funaki, M Itoh, T Fujiwara, K Yanai, M Sato, Y Numachi, S Yoshida, M Mizugak. Effects of haloperidol and cocaine pretreatments on brain distribution and kinetics of [11C]methamphetamine in methamphetamine sensitized dog: application of PET to drug pharmacokinetic study. Nuclear medicine and biology. vol 24. issue 2. 1997-06-19. PMID:9190247. |
in behavioral studies, haloperidol (a dopamine d2 receptor antagonist) prevents map-induced behavioral sensitization, and cocaine (a dopamine reuptake blocker) has the cross-behavioral sensitization with map. |
1997-06-19 |
2023-08-12 |
dog |
S R Letchworth, J B Daunais, A A Hedgecock, L J Porrin. Effects of chronic cocaine administration on dopamine transporter mRNA and protein in the rat. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098547. |
effects of chronic cocaine administration on dopamine transporter mrna and protein in the rat. |
1997-06-17 |
2023-08-12 |
rat |
S R Letchworth, J B Daunais, A A Hedgecock, L J Porrin. Effects of chronic cocaine administration on dopamine transporter mRNA and protein in the rat. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098547. |
chronic cocaine administration resulted in dose-dependent decreases in the density of dopamine transporter (dat) mrna in both the substantia nigra pars compacta and ventral tegmental area as shown by in situ hybridization histochemistry. |
1997-06-17 |
2023-08-12 |
rat |
B P Bowman, B Blatt, C M Kuh. Ontogeny of the behavioral response to dopamine agonists after chronic cocaine. Psychopharmacology. vol 129. issue 2. 1997-06-16. PMID:9040117. |
ontogeny of the behavioral response to dopamine agonists after chronic cocaine. |
1997-06-16 |
2023-08-12 |
rat |
B P Bowman, B Blatt, C M Kuh. Ontogeny of the behavioral response to dopamine agonists after chronic cocaine. Psychopharmacology. vol 129. issue 2. 1997-06-16. PMID:9040117. |
the behavioral response to separate and combined administration of dopamine d1 and d2 receptor agonists was assessed acutely and after chronic cocaine exposure (30 mg/kg s.c. b.i.d. |
1997-06-16 |
2023-08-12 |
rat |
R P Hammer, Y Egilmez, M W Emmett-Oglesb. Neural mechanisms of tolerance to the effects of cocaine. Behavioural brain research. vol 84. issue 1-2. 1997-06-13. PMID:9079787. |
the mechanism underlying this effect may involve an absolute or relative attenuation of dopamine response to cocaine challenge after frequent or repeated treatment in the nucleus accumbens (nac). |
1997-06-13 |
2023-08-12 |
human |
R P Hammer, Y Egilmez, M W Emmett-Oglesb. Neural mechanisms of tolerance to the effects of cocaine. Behavioural brain research. vol 84. issue 1-2. 1997-06-13. PMID:9079787. |
thus, a combination of various pharmacodynamic mechanisms and the attenuation of dopamine response induced by sufficient dose, duration and frequency of cocaine exposure ultimately invoke the transient development of tolerance to the reinforcing effects of cocaine. |
1997-06-13 |
2023-08-12 |
human |