| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A L Bittencourt, R N Takahash. Mazindol and lidocaine are antinociceptives in the mouse formalin model: involvement of dopamine receptor. European journal of pharmacology. vol 330. issue 2-3. 1997-09-22. PMID:9253942. |
), a dopamine d2 receptor antagonist, reduced the antinociceptive actions of mazindol and cocaine, while sch 23390, r(+)-7-chloro 8-hydroxy-3methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3 benzazepine (0.03 mg/kg, i.p. |
1997-09-22 |
2023-08-12 |
mouse |
| T E Schlaepfer, G D Pearlson, D F Wong, S Marenco, R F Dannal. PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects. The American journal of psychiatry. vol 154. issue 9. 1997-09-18. PMID:9286178. |
pet study of competition between intravenous cocaine and [11c]raclopride at dopamine receptors in human subjects. |
1997-09-18 |
2023-08-12 |
human |
| T E Schlaepfer, G D Pearlson, D F Wong, S Marenco, R F Dannal. PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects. The American journal of psychiatry. vol 154. issue 9. 1997-09-18. PMID:9286178. |
animal data suggest that the strong euphoriant effects of cocaine are related to the drug's enhancement of available dopamine at the synaptic cleft. |
1997-09-18 |
2023-08-12 |
human |
| A E Morgan, B Horan, S L Dewey, C R Ashb. Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 331. issue 1. 1997-09-12. PMID:9274936. |
repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. |
1997-09-12 |
2023-08-12 |
rat |
| A E Morgan, B Horan, S L Dewey, C R Ashb. Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 331. issue 1. 1997-09-12. PMID:9274936. |
cocaine produced a 400% increase in extracellular nucleus accumbens dopamine levels in control rats, whereas in 3,4-methylenedioxymethamphetamine treated rats the increase produced by cocaine was 800%, which was significantly different from controls. |
1997-09-12 |
2023-08-12 |
rat |
| C Xu, M E Reit. WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter. The Journal of pharmacology and experimental therapeutics. vol 282. issue 2. 1997-09-11. PMID:9262359. |
it has been suggested that cocaine and mazindol bind to separate sites on the dopamine transporter. |
1997-09-11 |
2023-08-12 |
human |
| C Xu, M E Reit. WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter. The Journal of pharmacology and experimental therapeutics. vol 282. issue 2. 1997-09-11. PMID:9262359. |
in the present study, we address this issue by examining the inhibition by mazindol of the binding of [3h]win 35,428 ([3h]2beta-carbomethyoxy-3beta-(4-fluorophenyl)-tropane), a phenyltropane analog of cocaine, and the inhibition by win 35,428 of [3h]mazindol binding to the cloned human dopamine transporter expressed in c6 glioma cells. |
1997-09-11 |
2023-08-12 |
human |
| C Xu, M E Reit. WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter. The Journal of pharmacology and experimental therapeutics. vol 282. issue 2. 1997-09-11. PMID:9262359. |
the present results suggest that complex interactions reported between cocaine and mazindol in inhibiting dopamine transport are beyond the level of ligand recognition. |
1997-09-11 |
2023-08-12 |
human |
| S Singh, G P Basmadjian, K S Avor, B Pouw, T W Seal. Synthesis and ligand binding studies of 4'-iodobenzoyl esters of tropanes and piperidines at the dopamine transporter. Journal of medicinal chemistry. vol 40. issue 16. 1997-09-10. PMID:9258354. |
an iodo group substitution at the 4'-position of cocaine decreased dopamine transporter binding potency, while a hydroxy or acetoxy group at the 2'-position exhibited increased binding potency for the dopamine transporter compared to cocaine (10- and 3.58-fold, respectively). |
1997-09-10 |
2023-08-12 |
Not clear |
| A E Morgan, S P Porter, F A Clarkson, N D Volkow, J S Fowler, S L Dewe. Direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215601. |
direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter. |
1997-09-09 |
2023-08-12 |
rat |
| A E Morgan, S P Porter, F A Clarkson, N D Volkow, J S Fowler, S L Dewe. Direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215601. |
using in vivo microdialysis techniques, the effects of rti-55 and/or cocaine on extracellular dopamine (da) concentrations were measured in the nucleus accumbens (nacc) of freely moving rats. |
1997-09-09 |
2023-08-12 |
rat |
| A E Morgan, S P Porter, F A Clarkson, N D Volkow, J S Fowler, S L Dewe. Direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215601. |
these findings indicate that rti-55, a drug that binds directly to the dopamine transporter (dat) with higher affinity than cocaine, does not appear to be effective in attenuating cocaine's effects on nacc dopamine levels. |
1997-09-09 |
2023-08-12 |
rat |
| N E Goeder. A neuroendocrine role in cocaine reinforcement. Psychoneuroendocrinology. vol 22. issue 4. 1997-09-05. PMID:9226728. |
in particular, the medial prefrontal cortex appears to be at least one brain region where dopamine and adrenocorticosteroids may interact to affect cocaine reinforcement. |
1997-09-05 |
2023-08-12 |
rat |
| S G Howard, R Fisher, C F Landr. Alterations in the spontaneous release of dopamine and the density of the DA D2 receptor mRNA after chronic postnatal exposure to cocaine. Brain research bulletin. vol 43. issue 1. 1997-09-04. PMID:9205803. |
alterations in the spontaneous release of dopamine and the density of the da d2 receptor mrna after chronic postnatal exposure to cocaine. |
1997-09-04 |
2023-08-12 |
rat |
| S G Howard, R Fisher, C F Landr. Alterations in the spontaneous release of dopamine and the density of the DA D2 receptor mRNA after chronic postnatal exposure to cocaine. Brain research bulletin. vol 43. issue 1. 1997-09-04. PMID:9205803. |
the influence of cocaine administration on dopamine (da) release and d2 dopamine receptor mrna levels was examined in developing rat brain. |
1997-09-04 |
2023-08-12 |
rat |
| Z Sarnyai, G L Kovác. Role of oxytocin in the neuroadaptation to drugs of abuse. Psychoneuroendocrinology. vol 19. issue 1. 1997-08-26. PMID:9210215. |
both morphine tolerance and dependence, and cocaine administration, increased dopamine utilization in the mesencephalon and in the nucleus accumbens, respectively. |
1997-08-26 |
2023-08-12 |
mouse |
| F Ferrari, D Giulian. Involvement of dopamine D2 receptors in the effect of cocaine on sexual behaviour and stretching-yawning of male rats. Neuropharmacology. vol 36. issue 6. 1997-08-18. PMID:9225304. |
involvement of dopamine d2 receptors in the effect of cocaine on sexual behaviour and stretching-yawning of male rats. |
1997-08-18 |
2023-08-12 |
rat |
| M S Kleven, W Koe. Discriminative stimulus properties of cocaine: enhancement by beta-adrenergic receptor antagonists. Psychopharmacology. vol 131. issue 3. 1997-08-14. PMID:9203242. |
although many of the behavioral effects of cocaine are widely believed to be mediated by blockade of dopamine transporters, recent studies suggest that norepinephrine (ne) may play a modulatory role. |
1997-08-14 |
2023-08-12 |
rat |
| J R Glowa, W E Fantegross. Effects of dopaminergic drugs on food- and cocaine-maintained responding. IV: Continuous cocaine infusions. Drug and alcohol dependence. vol 45. issue 1-2. 1997-08-01. PMID:9179509. |
as such, the effects of continuous infusions of cocaine are similar to those of other, longer-acting dopamine agonists. |
1997-08-01 |
2023-08-12 |
monkey |
| D M Wilson, A P Ferko, E J Barbieri, G J DiGregorio, E Bobyock, R McMichae. The interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164556. |
the interaction of dopamine, cocaine, and cocaethylene with ethanol on central nervous system depression in mice. |
1997-07-30 |
2023-08-12 |
mouse |