| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dasiel O Borroto-Escuela, Karolina Wydra, Ramon Fores-Pons, Lakshmi Vasudevan, Wilber Romero-Fernandez, Małgorzata Frankowska, Luca Ferraro, Sarah Beggiato, Minerva Crespo-Ramirez, Alicia Rivera, Luisa L Rocha, Miguel Perez de la Mora, Christophe Stove, Małgorzata Filip, Kjell Fux. The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders. Frontiers in pharmacology. vol 12. 2021-04-02. PMID:33790790. |
the balance of mu-opioid, dopamine d2 and adenosine a2a heteroreceptor complexes in the ventral striatal-pallidal gaba antireward neurons may have a significant role in morphine and cocaine use disorders. |
2021-04-02 |
2023-08-13 |
Not clear |
| Sunny Zhihong Jiang, Sean Sweat, Sam P Dahlke, Kathleen Loane, Gunner Drossel, Wenqin Xu, Hugo A Tejeda, Charles R Gerfen, Lee E Eide. Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 4. 2021-03-26. PMID:33268547. |
elucidation of the mechanism of dopamine signaling to erk that underlies plasticity in dopamine d1 receptor-expressing neurons leading to acquired cocaine preference is incomplete. |
2021-03-26 |
2023-08-13 |
mouse |
| Ching Mei Wu, Ted Weita La. Microglia depletion by PLX3397 has no effect on cocaine-induced behavioral sensitization in male mice. Brain research. vol 1761. 2021-03-21. PMID:33639199. |
for instance, cocaine can directly bind to surface receptors on microglia and trigger their release of interleukin-1β, which promotes addictive behaviors; however, cocaine also indirectly stimulates microglia by elevating dopamine, which causes microglia to impair long-lasting neuronal changes related to cocaine use. |
2021-03-21 |
2023-08-13 |
mouse |
| Susana Barbosa-Méndez, Alberto Salazar-Juáre. Prenatal and postnatal cocaine exposure enhances the induction and expression of locomotor sensitization to cocaine in rats. Reproductive toxicology (Elmsford, N.Y.). vol 93. 2021-03-19. PMID:32173415. |
it also produces changes in cocaine-induced dopamine release and increases cocaine self-administration and cocaine-induced conditioned place preference. |
2021-03-19 |
2023-08-13 |
rat |
| Wendy J Lynch, Anousheh Bakhti-Suroosh, Jean M Abel, Camilla Davi. Shifts in the neurobiological mechanisms motivating cocaine use with the development of an addiction-like phenotype in male rats. Psychopharmacology. vol 238. issue 3. 2021-03-15. PMID:33241478. |
the development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (nac) dopamine d |
2021-03-15 |
2023-08-13 |
rat |
| Sunil U Nayak, Stephanie Cicalese, Chris Tallarida, Chicora F Oliver, Scott M Rawl. Chemokine CCR5 and cocaine interactions in the brain: Cocaine enhances mesolimbic CCR5 mRNA levels and produces place preference and locomotor activation that are reduced by a CCR5 antagonist. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31557508. |
evidence that ccr5 knockout mice display fewer dopamine neurons, lower striatal dopamine levels, and reduced locomotor activation compared to wild types also suggest a link between ccr5 receptors and cocaine dependence. |
2021-03-08 |
2023-08-13 |
mouse |
| Rajesh Narendran, Neale Scott Mason, Michael L Himes, W Gordon Frankl. Imaging Cortical Dopamine Transmission in Cocaine Dependence: A [ Biological psychiatry. vol 88. issue 10. 2021-03-08. PMID:32507390. |
imaging cortical dopamine transmission in cocaine dependence: a [ positron emission tomography studies have demonstrated less dopamine d |
2021-03-08 |
2023-08-13 |
Not clear |
| Nicholas L Mervosh, Rashaun Wilson, Navin Rauniyar, Rebecca S Hofford, Munir Gunes Kutlu, Erin S Calipari, TuKiet T Lam, Drew D Kiral. Granulocyte-Colony-Stimulating Factor Alters the Proteomic Landscape of the Ventral Tegmental Area. Proteomes. vol 6. issue 4. 2021-02-18. PMID:30249060. |
cocaine addiction is characterized by aberrant plasticity of the mesolimbic dopamine circuit, leading to dysregulation of motivation to seek and take drug. |
2021-02-18 |
2023-08-13 |
mouse |
| Nicholas L Mervosh, Rashaun Wilson, Navin Rauniyar, Rebecca S Hofford, Munir Gunes Kutlu, Erin S Calipari, TuKiet T Lam, Drew D Kiral. Granulocyte-Colony-Stimulating Factor Alters the Proteomic Landscape of the Ventral Tegmental Area. Proteomes. vol 6. issue 4. 2021-02-18. PMID:30249060. |
we have recently identified granulocyte-colony stimulating factor (g-csf) as a soluble cytokine that alters the behavioral response to cocaine and which increases dopamine release from the ventral tegmental area (vta). |
2021-02-18 |
2023-08-13 |
mouse |
| Camilla Nicolucci, Mariana Lapo Pais, A C Santos, Fabiana M Ribeiro, Pedro M C C Encarnação, Ana L M Silva, I F Castro, Pedro M M Correia, João F C A Veloso, Julie Reis, Marina Z Lopes, Maria F Botelho, Frederico C Pereira, Denise G Prioll. Single Low Dose of Cocaine-Structural Brain Injury Without Metabolic and Behavioral Changes. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584173. |
cocaine addicts have shown glucose metabolism changes related to dopamine brain activity and reduced volume of striatal gray matter. |
2021-02-16 |
2023-08-13 |
mouse |
| Gregory L Powell, Mark D Namba, Annika Vannan, John Paul Bonadonna, Andrew Carlson, Rachel Mendoza, Peng-Jen Chen, Robert R Luetdke, Benjamin E Blass, Janet L Neisewande. The Long-Acting D3 Partial Agonist MC-25-41 Attenuates Motivation for Cocaine in Sprague-Dawley Rats. Biomolecules. vol 10. issue 7. 2021-02-12. PMID:32708461. |
the dopamine d3 receptor is a prime target for developing treatments for cocaine use disorders (cuds). |
2021-02-12 |
2023-08-13 |
rat |
| Silvia Corongiu, Christian Dessì, Cristina Cadon. Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse. Addiction biology. vol 25. issue 1. 2021-02-10. PMID:30779271. |
adolescent rats showed greater increase of dopamine in the nac shell following nicotine (0.4 mg/kg), thc (1.0 mg/kg), and morphine (1.0 mg/kg), in the nac core following nicotine and morphine, and in the dls following thc, morphine, and cocaine (10 mg/kg). |
2021-02-10 |
2023-08-13 |
rat |
| Emily M Black, Rodrigo A Españ. D-amphetamine maintenance treatment goes a long way: lasting therapeutic effects on cocaine behavioral effects and cocaine potency at the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-02-05. PMID:32859997. |
d-amphetamine maintenance treatment goes a long way: lasting therapeutic effects on cocaine behavioral effects and cocaine potency at the dopamine transporter. |
2021-02-05 |
2023-08-13 |
Not clear |
| Zachary D Brodnik, Wei Xu, Aashita Batra, Stacia I Lewandowski, Christina M Ruiz, Ole V Mortensen, Sandhya Kortagere, Stephen V Mahler, Rodrigo A Españ. Chemogenetic Manipulation of Dopamine Neurons Dictates Cocaine Potency at Distal Dopamine Transporters. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 45. 2021-02-01. PMID:33046544. |
chemogenetic manipulation of dopamine neurons dictates cocaine potency at distal dopamine transporters. |
2021-02-01 |
2023-08-13 |
Not clear |
| Zachary D Brodnik, Wei Xu, Aashita Batra, Stacia I Lewandowski, Christina M Ruiz, Ole V Mortensen, Sandhya Kortagere, Stephen V Mahler, Rodrigo A Españ. Chemogenetic Manipulation of Dopamine Neurons Dictates Cocaine Potency at Distal Dopamine Transporters. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 45. 2021-02-01. PMID:33046544. |
the reinforcing efficacy of cocaine is largely determined by its capacity to inhibit the dopamine transporter (dat), and emerging evidence suggests that differences in cocaine potency are linked to several symptoms of cocaine use disorder. |
2021-02-01 |
2023-08-13 |
Not clear |
| Carolyn G Sweeney, Patrick J Kearney, Rita R Fagan, Lindsey A Smith, Nicholas C Bolden, Rubing Zhao-Shea, Iris V Rivera, Jenya Kolpakova, Jun Xie, Guangping Gao, Andrew R Tapper, Gilles E Martin, Haley E Melikia. Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 2. 2020-12-28. PMID:31277075. |
conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for rit2 gtpase in acute cocaine response and striatal function. |
2020-12-28 |
2023-08-13 |
Not clear |
| Zachary D Brodnik, Emily M Black, Rodrigo A Españ. Accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 3. 2020-12-28. PMID:31539899. |
accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress. |
2020-12-28 |
2023-08-13 |
rat |
| Zachary D Brodnik, Emily M Black, Rodrigo A Españ. Accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 3. 2020-12-28. PMID:31539899. |
we paired this model with in vivo fast scan cyclic voltammetry in freely moving rats to test for differences in dopamine signaling in the nucleus accumbens core at baseline, in response to a single dose of cocaine, and in response to cocaine-paired cues. |
2020-12-28 |
2023-08-13 |
rat |
| Zachary D Brodnik, Emily M Black, Rodrigo A Españ. Accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 3. 2020-12-28. PMID:31539899. |
together, our studies demonstrate that susceptibility to traumatic stress is associated with a cocaine use-vulnerable phenotype and suggests that differences in phasic dopamine signaling architecture may contribute to the process by which this vulnerability occurs. |
2020-12-28 |
2023-08-13 |
rat |
| Clifford M Cassidy, Kenneth M Carpenter, Anna B Konova, Victoria Cheung, Alexander Grassetti, Luigi Zecca, Anissa Abi-Dargham, Diana Martinez, Guillermo Horg. Evidence for Dopamine Abnormalities in the Substantia Nigra in Cocaine Addiction Revealed by Neuromelanin-Sensitive MRI. The American journal of psychiatry. vol 177. issue 11. 2020-12-14. PMID:32854531. |
evidence for dopamine abnormalities in the substantia nigra in cocaine addiction revealed by neuromelanin-sensitive mri. |
2020-12-14 |
2023-08-13 |
human |