| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susana Paredes-Zúñiga, Fernando Ormeño, Miguel L Allend. Triadimefon triggers circling behavior and conditioned place preference/aversion in zebrafish in a dose dependent manner. Neurotoxicology and teratology. vol 86. 2021-08-25. PMID:33839247. |
for vertebrates, one of its side effects is the binding to the dopamine transporter increasing the levels of synaptic dopamine, similarly to cocaine. |
2021-08-25 |
2023-08-13 |
zebrafish |
| Aaron Caccamise, Erik Van Newenhizen, John R Mantsc. Neurochemical mechanisms and neurocircuitry underlying the contribution of stress to cocaine seeking. Journal of neurochemistry. vol 157. issue 5. 2021-08-24. PMID:33660857. |
crf promotes the activation of vta dopamine neurons that innervate the prelimbic prefrontal cortex resulting in d1 receptor-dependent excitation of a pathway to the nucleus accumbens core that mediates cocaine seeking. |
2021-08-24 |
2023-08-13 |
Not clear |
| Zhijun Diao, Yuanyuan Di, Meilin Wu, Chenyang Zhai, Mengsi Kang, Yongfeng Li, Yingxun Liu, Chunling Wei, Qiaohua Zheng, Jing Han, Zhiqiang Liu, Yingfang Tian, Wei Re. Single Exposure to Cocaine Impairs Reinforcement Learning by Potentiating the Activity of Neurons in the Direct Striatal Pathway in Mice. Neuroscience bulletin. vol 37. issue 8. 2021-08-18. PMID:33905097. |
either a single exposure to cocaine or reinforcement learning potentiates the glutamatergic synapses on msns expressing the striatal dopamine 1 (d1) receptor (d1-msns). |
2021-08-18 |
2023-08-13 |
mouse |
| Patricia Rivera, Jesús Aranda, Francisco Alén, Antonio Vargas, Antonia Serrano, Francisco Javier Pavón, Laura Orio, Leticia Rubio, Rosario Moratalla, Fernando Rodríguez de Fonseca, Juan Suáre. Sex-specific behavioral and neurogenic responses to cocaine in mice lacking and blocking dopamine D1 or dopamine D2 receptors. The Journal of comparative neurology. vol 529. issue 8. 2021-08-16. PMID:33047300. |
sex-specific behavioral and neurogenic responses to cocaine in mice lacking and blocking dopamine d1 or dopamine d2 receptors. |
2021-08-16 |
2023-08-13 |
mouse |
| Patricia Rivera, Jesús Aranda, Francisco Alén, Antonio Vargas, Antonia Serrano, Francisco Javier Pavón, Laura Orio, Leticia Rubio, Rosario Moratalla, Fernando Rodríguez de Fonseca, Juan Suáre. Sex-specific behavioral and neurogenic responses to cocaine in mice lacking and blocking dopamine D1 or dopamine D2 receptors. The Journal of comparative neurology. vol 529. issue 8. 2021-08-16. PMID:33047300. |
however, the sex-specific role of dopamine d1 and d2 receptors (d1r, d2r) in the deleterious effect of cocaine on adult neurogenesis has not been described yet. |
2021-08-16 |
2023-08-13 |
mouse |
| Shannon L Cole, Ramesh Chandra, Maya Harris, Ishan Patel, Torrance Wang, Hyunjae Kim, Leah Jensen, Scott J Russo, Gustavo Turecki, Amy M Gancarz-Kausch, David M Dietz, Mary Kay Lob. Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34187517. |
further, mitochondria are differentially regulated by cocaine in dopamine receptor-1 containing medium spiny neurons (d1-msns) vs dopamine receptor-2 (d2)-msns. |
2021-08-12 |
2023-08-13 |
human |
| Fernando B de Moura, Alexander Sherwood, Thomas E Prisinzano, Carol A Paronis, Jack Bergman, Stephen J Kohu. Reinforcing effects of synthetic cathinones in rhesus monkeys: Dose-response and behavioral economic analyses. Pharmacology, biochemistry, and behavior. vol 202. 2021-08-10. PMID:33444603. |
the reinforcing effects of selected cathinones (e.g., mdpv, αpvp, mcat, and methylone) with a range of pharmacological effects at dopamine and serotonin transporters were compared to cocaine and mdma using dose-response analysis under a simple fr schedule and behavioral economic procedures that generated demand curves for two doses of each drug. |
2021-08-10 |
2023-08-13 |
human |
| Anna Terem, Ben Jerry Gonzales, Noa Peretz-Rivlin, Reut Ashwal-Fluss, Noa Bleistein, Maria Del Mar Reus-Garcia, Diptendu Mukherjee, Maya Groysman, Ami Citr. Claustral Neurons Projecting to Frontal Cortex Mediate Contextual Association of Reward. Current biology : CB. vol 30. issue 18. 2021-08-09. PMID:32707061. |
this strategy resolves the role of a defined network of claustrum neurons expressing dopamine d1 receptors and projecting to frontal cortex in the acquisition of cocaine conditioned-place preference and real-time optogenetic conditioned-place preference. |
2021-08-09 |
2023-08-13 |
Not clear |
| Jing Deng, Kyungbo Kim, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane. Addiction biology. 2021-08-07. PMID:34363291. |
cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane. |
2021-08-07 |
2023-08-13 |
rat |
| Jing Deng, Kyungbo Kim, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane. Addiction biology. 2021-08-07. PMID:34363291. |
cocaine blocks dopamine uptake via dopamine transporter (dat) on plasma membrane of neuron cells and, as a result, produces the high and induces dat trafficking to plasma membrane which contributes to the drug seeking or craving. |
2021-08-07 |
2023-08-13 |
rat |
| Ahmed Hasbi, Meenalochani Sivasubramanian, Marija Milenkovic, Kristina Komarek, Bertha K Madras, Susan R Georg. Dopamine D1-D2 receptor heteromer expression in key brain regions of rat and higher species: Upregulation in rat striatum after cocaine administration. Neurobiology of disease. vol 143. 2021-08-05. PMID:32679312. |
dopamine d1-d2 receptor heteromer expression in key brain regions of rat and higher species: upregulation in rat striatum after cocaine administration. |
2021-08-05 |
2023-08-13 |
rat |
| Marie A Doyle, Vedrana Bali, Andrew L Eagle, Ali R Stark, Barbara Fallon, Rachael L Neve, A J Robison, Michelle S Mazei-Robiso. Serum- and glucocorticoid-inducible kinase 1 activity in ventral tegmental area dopamine neurons regulates cocaine conditioned place preference but not cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 9. 2021-08-04. PMID:34007042. |
serum- and glucocorticoid-inducible kinase 1 activity in ventral tegmental area dopamine neurons regulates cocaine conditioned place preference but not cocaine self-administration. |
2021-08-04 |
2023-08-13 |
Not clear |
| Horia Pribiag, Sora Shin, Eric Hou-Jen Wang, Fangmiao Sun, Paul Datta, Alexander Okamoto, Hayden Guss, Akanksha Jain, Xiao-Yun Wang, Bruna De Freitas, Patrick Honma, Stefan Pate, Varoth Lilascharoen, Yulong Li, Byung Kook Li. Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking. Neuron. vol 109. issue 13. 2021-07-23. PMID:34048697. |
ventral pallidum drd3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking. |
2021-07-23 |
2023-08-13 |
Not clear |
| Horia Pribiag, Sora Shin, Eric Hou-Jen Wang, Fangmiao Sun, Paul Datta, Alexander Okamoto, Hayden Guss, Akanksha Jain, Xiao-Yun Wang, Bruna De Freitas, Patrick Honma, Stefan Pate, Varoth Lilascharoen, Yulong Li, Byung Kook Li. Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking. Neuron. vol 109. issue 13. 2021-07-23. PMID:34048697. |
here, we demonstrate that dopamine receptor d3 (drd3)-dependent plasticity in the ventral pallidum (vp) drives potentiation of dopamine release in the nucleus accumbens during relapse to cocaine seeking after abstinence. |
2021-07-23 |
2023-08-13 |
Not clear |
| Marco Leyto. Ubiquitous Dopamine Deficit Hypotheses in Cocaine Use Disorder Lack Support. The American journal of psychiatry. vol 178. issue 5. 2021-07-22. PMID:33979542. |
ubiquitous dopamine deficit hypotheses in cocaine use disorder lack support. |
2021-07-22 |
2023-08-13 |
Not clear |
| Clifford M Cassidy, Anna B Konova, Anissa Abi-Dargham, Diana Martinez, Guillermo Horg. Ubiquitous Dopamine Deficit Hypotheses in Cocaine Use Disorder Lack Support: Response to Leyton. The American journal of psychiatry. vol 178. issue 5. 2021-07-22. PMID:33979543. |
ubiquitous dopamine deficit hypotheses in cocaine use disorder lack support: response to leyton. |
2021-07-22 |
2023-08-13 |
Not clear |
| J R Melchior, R E Perez, G J Salimando, J R Luchsinger, A Basu, D G Winde. Cocaine Augments Dopamine Mediated Inhibition of Neuronal Activity in the Dorsal Bed Nucleus of the Stria Terminalis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021-07-11. PMID:34035141. |
cocaine augments dopamine mediated inhibition of neuronal activity in the dorsal bed nucleus of the stria terminalis. |
2021-07-11 |
2023-08-13 |
Not clear |
| Regina Célia Cussa Kubrusly, Robertta Silva Martins, Lisiane de Santana Souza, Mariana Pinheiro de Carvalho, Vladimir Pedro Peralva Borges-Martins, Matheus Figueiredo Sathler, Danielle Dias Pinto Ferreira, Maurício Dos Santos Pereira, Ney Ronner Peccinalli, Pablo Pandolfo, Ricardo Augusto de Melo Reis, Gustavo Costa Ferreira, Alex Christian Manhãe. Single Cocaine Exposure Inhibits GABA Uptake via Dopamine D1-Like Receptors in Adolescent Mice Frontal Cortex. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32696437. |
single cocaine exposure inhibits gaba uptake via dopamine d1-like receptors in adolescent mice frontal cortex. |
2021-07-09 |
2023-08-13 |
mouse |
| Regina Célia Cussa Kubrusly, Robertta Silva Martins, Lisiane de Santana Souza, Mariana Pinheiro de Carvalho, Vladimir Pedro Peralva Borges-Martins, Matheus Figueiredo Sathler, Danielle Dias Pinto Ferreira, Maurício Dos Santos Pereira, Ney Ronner Peccinalli, Pablo Pandolfo, Ricardo Augusto de Melo Reis, Gustavo Costa Ferreira, Alex Christian Manhãe. Single Cocaine Exposure Inhibits GABA Uptake via Dopamine D1-Like Receptors in Adolescent Mice Frontal Cortex. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32696437. |
cocaine (coc) is a psychostimulant that acts by increasing catecholaminergic neurotransmission mainly due to its effects on the dopamine transporter (dat). |
2021-07-09 |
2023-08-13 |
mouse |
| Christopher W Tschumi, Anna W Daszkowski, Amanda L Sharpe, Marta Trzeciak, Michael J Beckstea. A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine. Addiction biology. vol 25. issue 4. 2021-06-28. PMID:31062485. |
ethanol acutely increases dopamine neuron excitability, and psychostimulants such as cocaine or methamphetamine increase extracellular dopamine through inhibition of uptake through the dopamine transporter (dat) and/or vesicular monoamine transporter 2 (vmat2). |
2021-06-28 |
2023-08-13 |
mouse |