| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dasiel O Borroto-Escuela, Jens Carlsson, Patricia Ambrogini, Manuel Narváez, Karolina Wydra, Alexander O Tarakanov, Xiang Li, Carmelo Millón, Luca Ferraro, Riccardo Cuppini, Sergio Tanganelli, Fang Liu, Malgorzata Filip, Zaida Diaz-Cabiale, Kjell Fux. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28270751. |
neuromodulation of neuronal networks in cocaine use disorder via dopamine (da) and adenosine signals involve a2ar-d2r and a2ar-d2r-sigma1r heteroreceptor complexes in the dorsal and ventral striatum. |
2020-09-30 |
2023-08-13 |
Not clear |
| Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. |
the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. |
2020-09-30 |
2023-08-13 |
mouse |
| Beth Ann Rice, Raza Tariq, Chana K Akin. Intramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization. Current psychopharmacology. vol 6. issue 1. 2020-09-30. PMID:29104856. |
in animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ahmed Hasbi, Melissa L Perreault, Maurice Y F Shen, Theresa Fan, Tuan Nguyen, Mohammed Alijaniaram, Tomek J Banasikowski, Anthony A Grace, Brian F O'Dowd, Paul J Fletcher, Susan R Georg. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29354053. |
activation of dopamine d1-d2 receptor complex attenuates cocaine reward and reinstatement of cocaine-seeking through inhibition of darpp-32, erk, and Δfosb. |
2020-09-30 |
2023-08-13 |
rat |
| Sheng Zhang, Wuyi Wang, Simon Zhornitsky, Chiang-Shan R L. Resting State Functional Connectivity of the Lateral and Medial Hypothalamus in Cocaine Dependence: An Exploratory Study. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30100886. |
the role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and mdma. |
2020-09-30 |
2023-08-13 |
Not clear |
| Suchan Chang, Yeonhee Ryu, Yu Fan, Se Kyun Bang, Nam Jun Kim, Jin Gyeom Lee, Jin Mook Kim, Bong Hyo Lee, Chae Ha Yang, Hee Young Ki. Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31555084. |
our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating gaba neurons in the ventral tegmental area (vta) and dopamine (da) release in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
Not clear |
| Karen Brami-Cherrier, Robert G Lewis, Marlene Cervantes, Yu Liu, Paola Tognini, Pierre Baldi, Paolo Sassone-Corsi, Emiliana Borrell. Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation. Nature communications. vol 11. issue 1. 2020-09-30. PMID:32895370. |
addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. |
2020-09-30 |
2023-08-13 |
mouse |
| Takato Hiranit. DAT Conformation Does Not Predict the Ability of Atypical Dopamine Uptake Inhibitors to Substitute for Cocaine. Journal of alcoholism and drug dependence. vol 4. issue 4. 2020-09-29. PMID:27588299. |
dat conformation does not predict the ability of atypical dopamine uptake inhibitors to substitute for cocaine. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kenneth Blum, Rajendra D Badgaiyan, Eric R Braverman, Kristina Dushaj, Mona Li, Peter K Thanos, Zsolt Demetrovics, Marcelo Feb. Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. Journal of reward deficiency syndrome and addiction science. vol 2. issue 1. 2020-09-29. PMID:28317038. |
it is also well accepted that psychostimulants such as cocaine affect not only the release of neuronal dopamine at the nucleus accumbens (nac), but also has powerful inhibitory actions on the dopamine transporter system. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rick E Bernardi, Laura Broccoli, Natalie Hirth, Nicholas J Justice, Jan M Deussing, Anita C Hansson, Rainer Spanage. Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:29180955. |
we then studied cocaine sensitization, self-administration, and reinstatement in inducible crhr1 knockouts using the creert2/loxp in either dopamine transporter (dat)-containing neurons (dat-crhr1) or dopamine receptor 1 (d1)-containing neurons (d1-crhr1). |
2020-09-29 |
2023-08-13 |
mouse |
| Katie E Yoest, Jennifer A Cummings, Jill B Becke. Oestradiol influences on dopamine release from the nucleus accumbens shell: sex differences and the role of selective oestradiol receptor subtypes. British journal of pharmacology. vol 176. issue 21. 2020-09-21. PMID:30381823. |
in this study, we tested the acute effect of oestradiol on dopamine release in the nucleus accumbens (nac) shell after cocaine administration and investigated which oestradiol receptors (ers) contribute to sex differences in the response to cocaine. |
2020-09-21 |
2023-08-13 |
Not clear |
| Lillian J Brady, Rebecca S Hofford, Jennifer Tat, Erin S Calipari, Drew D Kiral. Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice. ACS chemical neuroscience. vol 10. issue 10. 2020-09-04. PMID:31479229. |
g-csf treatment enhanced the ability of cocaine to inhibit dopamine clearance; however, this effect was observed specifically during pro/estrus, when circulating ovarian hormone levels were high. |
2020-09-04 |
2023-08-13 |
mouse |
| Jin Cheng, Siyi Wang, Weiwei Lin, Nan Wu, Yuanqiang Wang, Maozi Chen, Xiang-Qun Xie, Zhiwei Fen. Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose. ACS chemical neuroscience. vol 10. issue 8. 2020-08-18. PMID:31257858. |
sequentially, we looked into the detail of (1) the addiction to cocaine and fentanyl by binding to the dopamine transporter and the μ opioid receptor (dat and μor, respectively), (2) the potential drug-drug interaction of cocaine and fentanyl via p-glycoprotein (p-gp) efflux, (3) the metabolism of cocaine and fentanyl in cyp3a4, and (4) the physiologically based pharmacokinetic (pbpk) model for two drugs and their drug-drug interaction at the absorption, distribution, metabolism, and excretion (adme) level. |
2020-08-18 |
2023-08-13 |
Not clear |
| Alex B Kawa, Alec C Valenta, Robert T Kennedy, Terry E Robinso. Incentive and dopamine sensitization produced by intermittent but not long access cocaine self-administration. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:30968487. |
incentive and dopamine sensitization produced by intermittent but not long access cocaine self-administration. |
2020-08-11 |
2023-08-13 |
rat |
| Alex B Kawa, Alec C Valenta, Robert T Kennedy, Terry E Robinso. Incentive and dopamine sensitization produced by intermittent but not long access cocaine self-administration. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:30968487. |
to further address this issue, we compared the effects of long access (lga) cocaine self-administration, which is widely used to model the transition to addiction, with intermittent access (inta), which is thought to better reflect the pattern of drug use in humans, on the ability of a single, self-administered injection of cocaine to increase dopamine (da) overflow in the core of the nucleus accumbens (using in vivo microdialysis), and to produce addiction-like behavior. |
2020-08-11 |
2023-08-13 |
rat |
| Cody A Siciliano, Madelyn I Mauterer, Steve C Fordahl, Sara R Jone. Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:31111573. |
modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats. |
2020-08-11 |
2023-08-13 |
human |
| Cody A Siciliano, Madelyn I Mauterer, Steve C Fordahl, Sara R Jone. Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:31111573. |
although it has been suggested that amphetamine treatment reduces cocaine intake as an agonist replacement therapy, we have shown recently that multiple aspects of dopamine signaling are altered by cocaine self-administration and returned to pre-cocaine function by amphetamine treatment in the nucleus accumbens of male rats. |
2020-08-11 |
2023-08-13 |
human |
| Nadia R P W Hutten, Laura Steenbergen, Lorenza S Colzato, Bernhard Hommel, Eef L Theunissen, Johannes G Ramaekers, Kim P C Kuyper. Cocaine enhances figural, but impairs verbal 'flexible' divergent thinking. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 7. 2020-08-10. PMID:31255395. |
given that cocaine is likely to enhance dopamine (da) levels, which in turn are positively associated with divergent thinking (dt); is a possibility that is tested in the present study. |
2020-08-10 |
2023-08-13 |
rat |
| Ellie-Anna Minogianis, Waqqas M Shams, Omar S Mabrouk, Jenny-Marie T Wong, Wayne G Brake, Robert T Kennedy, Patrick du Souich, Anne-Noël Samah. Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum. The European journal of neuroscience. vol 50. issue 3. 2020-06-30. PMID:29757478. |
varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum. |
2020-06-30 |
2023-08-13 |
rat |