| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudia A Chiriboga, Louise Kuhn, Gail A Wasserma. Neurobehavioral and Developmental Traiectories Associated with Level of Prenatal Cocaine Exposure. Journal of neurology and psychology. vol 2. issue 3. 2020-10-01. PMID:25664330. |
in experimental models, prenatal cocaine exposure has been found to perturb gaba and dopamine development. |
2020-10-01 |
2023-08-13 |
Not clear |
| Takato Hiranita, Gregory T Collin. Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies. Journal of alcoholism and drug dependence. vol 3. issue 4. 2020-10-01. PMID:27390753. |
differential roles for dopamine d1-like and d2-like receptors in mediating the reinforcing effects of cocaine: convergent evidence from pharmacological and genetic studies. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kenneth Blum, Peter K Thanos, Marlene Oscar-Berman, Marcelo Febo, David Baron, Rajendra D Badgaiyan, Eliot Gardner, Zsolt Demetrovics, Claudia Fahlke, Brett C Haberstick, Kristina Dushaj, Mark S Gol. Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction. Journal of reward deficiency syndrome. vol 1. issue 3. 2020-10-01. PMID:27398406. |
shows that in a self-administration paradigm, (chronic) excessive use of cocaine is caused by decreased phasic dopamine signaling in the striatum. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ravi Doobay, Lili Sun, Amish Shah, Pardeep Masuta, Zachary Shepher. SSRI Facilitated Crack Dancing. Case reports in neurological medicine. vol 2017. 2020-10-01. PMID:28487792. |
it consists of uncontrolled writhing movements secondary to excess dopamine from cocaine use. |
2020-10-01 |
2023-08-13 |
Not clear |
| Etienne Cartier, Jennie Garcia-Olivares, Eric Janezic, Juan Viana, Michael Moore, Min Landon Lin, Jeffrey L Caplan, Gonzalo Torres, Yong-Hwan Ki. The SUMO-Conjugase Ubc9 Prevents the Degradation of the Dopamine Transporter, Enhancing Its Cell Surface Level and Dopamine Uptake. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:30828290. |
the dat is the molecular target for cocaine and amphetamine as well as a number of pathological conditions including autism spectrum disorders, attention-deficit hyperactivity disorder (adhd), dopamine transporter deficiency syndrome (dtds), and parkinson's disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sameer Taywade, Madhavi Tripathi, Vivek Tandon, Chandan Jyoti Das, Nishikant Avinash Damle, Shamim Ahmed Shamim, Parul Thukral, Chandrasekhar Ba. Tc-99m TRODAT uptake in an osteoid tumor of clivus. Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. vol 31. issue 4. 2020-09-30. PMID:27833323. |
tc-99m trodat is cocaine analog and binds to the dopamine transporter |
2020-09-30 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Jens Carlsson, Patricia Ambrogini, Manuel Narváez, Karolina Wydra, Alexander O Tarakanov, Xiang Li, Carmelo Millón, Luca Ferraro, Riccardo Cuppini, Sergio Tanganelli, Fang Liu, Malgorzata Filip, Zaida Diaz-Cabiale, Kjell Fux. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28270751. |
neuromodulation of neuronal networks in cocaine use disorder via dopamine (da) and adenosine signals involve a2ar-d2r and a2ar-d2r-sigma1r heteroreceptor complexes in the dorsal and ventral striatum. |
2020-09-30 |
2023-08-13 |
Not clear |
| Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. |
the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. |
2020-09-30 |
2023-08-13 |
mouse |
| Beth Ann Rice, Raza Tariq, Chana K Akin. Intramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization. Current psychopharmacology. vol 6. issue 1. 2020-09-30. PMID:29104856. |
in animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ahmed Hasbi, Melissa L Perreault, Maurice Y F Shen, Theresa Fan, Tuan Nguyen, Mohammed Alijaniaram, Tomek J Banasikowski, Anthony A Grace, Brian F O'Dowd, Paul J Fletcher, Susan R Georg. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29354053. |
activation of dopamine d1-d2 receptor complex attenuates cocaine reward and reinstatement of cocaine-seeking through inhibition of darpp-32, erk, and Δfosb. |
2020-09-30 |
2023-08-13 |
rat |
| Sheng Zhang, Wuyi Wang, Simon Zhornitsky, Chiang-Shan R L. Resting State Functional Connectivity of the Lateral and Medial Hypothalamus in Cocaine Dependence: An Exploratory Study. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30100886. |
the role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and mdma. |
2020-09-30 |
2023-08-13 |
Not clear |
| Suchan Chang, Yeonhee Ryu, Yu Fan, Se Kyun Bang, Nam Jun Kim, Jin Gyeom Lee, Jin Mook Kim, Bong Hyo Lee, Chae Ha Yang, Hee Young Ki. Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31555084. |
our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating gaba neurons in the ventral tegmental area (vta) and dopamine (da) release in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
Not clear |
| Karen Brami-Cherrier, Robert G Lewis, Marlene Cervantes, Yu Liu, Paola Tognini, Pierre Baldi, Paolo Sassone-Corsi, Emiliana Borrell. Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation. Nature communications. vol 11. issue 1. 2020-09-30. PMID:32895370. |
addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. |
2020-09-30 |
2023-08-13 |
mouse |
| Takato Hiranit. DAT Conformation Does Not Predict the Ability of Atypical Dopamine Uptake Inhibitors to Substitute for Cocaine. Journal of alcoholism and drug dependence. vol 4. issue 4. 2020-09-29. PMID:27588299. |
dat conformation does not predict the ability of atypical dopamine uptake inhibitors to substitute for cocaine. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kenneth Blum, Rajendra D Badgaiyan, Eric R Braverman, Kristina Dushaj, Mona Li, Peter K Thanos, Zsolt Demetrovics, Marcelo Feb. Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. Journal of reward deficiency syndrome and addiction science. vol 2. issue 1. 2020-09-29. PMID:28317038. |
it is also well accepted that psychostimulants such as cocaine affect not only the release of neuronal dopamine at the nucleus accumbens (nac), but also has powerful inhibitory actions on the dopamine transporter system. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rick E Bernardi, Laura Broccoli, Natalie Hirth, Nicholas J Justice, Jan M Deussing, Anita C Hansson, Rainer Spanage. Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:29180955. |
we then studied cocaine sensitization, self-administration, and reinstatement in inducible crhr1 knockouts using the creert2/loxp in either dopamine transporter (dat)-containing neurons (dat-crhr1) or dopamine receptor 1 (d1)-containing neurons (d1-crhr1). |
2020-09-29 |
2023-08-13 |
mouse |
| Katie E Yoest, Jennifer A Cummings, Jill B Becke. Oestradiol influences on dopamine release from the nucleus accumbens shell: sex differences and the role of selective oestradiol receptor subtypes. British journal of pharmacology. vol 176. issue 21. 2020-09-21. PMID:30381823. |
in this study, we tested the acute effect of oestradiol on dopamine release in the nucleus accumbens (nac) shell after cocaine administration and investigated which oestradiol receptors (ers) contribute to sex differences in the response to cocaine. |
2020-09-21 |
2023-08-13 |
Not clear |
| Lillian J Brady, Rebecca S Hofford, Jennifer Tat, Erin S Calipari, Drew D Kiral. Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice. ACS chemical neuroscience. vol 10. issue 10. 2020-09-04. PMID:31479229. |
g-csf treatment enhanced the ability of cocaine to inhibit dopamine clearance; however, this effect was observed specifically during pro/estrus, when circulating ovarian hormone levels were high. |
2020-09-04 |
2023-08-13 |
mouse |
| Jin Cheng, Siyi Wang, Weiwei Lin, Nan Wu, Yuanqiang Wang, Maozi Chen, Xiang-Qun Xie, Zhiwei Fen. Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose. ACS chemical neuroscience. vol 10. issue 8. 2020-08-18. PMID:31257858. |
sequentially, we looked into the detail of (1) the addiction to cocaine and fentanyl by binding to the dopamine transporter and the μ opioid receptor (dat and μor, respectively), (2) the potential drug-drug interaction of cocaine and fentanyl via p-glycoprotein (p-gp) efflux, (3) the metabolism of cocaine and fentanyl in cyp3a4, and (4) the physiologically based pharmacokinetic (pbpk) model for two drugs and their drug-drug interaction at the absorption, distribution, metabolism, and excretion (adme) level. |
2020-08-18 |
2023-08-13 |
Not clear |