| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Charles W Schindler, Gilberto N Carmon. Effects of dopamine agonists and antagonists on locomotor activity in male and female rats. Pharmacology, biochemistry, and behavior. vol 72. issue 4. 2003-01-08. PMID:12062575. |
these results suggest that the differences between males and females in their locomotor response to cocaine can be at least partially attributed to differences in the function of dopamine d1 and d2 receptors. |
2003-01-08 |
2023-08-12 |
rat |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
the effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
the current experiment evaluated the duration-dependent nature of the induction of behavioral tolerance and changes in dopamine autoreceptor function by continuously administering cocaine for different durations. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
continuous cocaine administration did induce dopamine autoreceptor supersensitivity. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
different continuous cocaine durations may induce differential degrees of dopamine autoreceptor supersensitivity. |
2003-01-08 |
2023-08-12 |
human |
| Ashwin A Patkar, Kevin P Hill, Robert C Sterling, Edward Gottheil, Wade H Berrettini, Stephen P Weinstei. Serum prolactin and response to treatment among cocaine-dependent individuals. Addiction biology. vol 7. issue 1. 2002-12-23. PMID:11900622. |
we investigated whether basal serum prolactin, a measure of central dopamine activity, differed between cocaine-dependent subjects and controls, and whether prolactin levels among cocaine patients were related to their response to treatment. |
2002-12-23 |
2023-08-12 |
human |
| Robert Ranaldi, William L Woolverto. Self-administration of cocaine: scopolamine combinations by rhesus monkeys. Psychopharmacology. vol 161. issue 4. 2002-12-23. PMID:12073173. |
several halogenated analogs of benztropine (bzt) have previously been characterized as potent dopamine (da) uptake inhibitors with diminished reinforcing effects relative to cocaine. |
2002-12-23 |
2023-08-12 |
monkey |
| J W Grimm, Y Shaham, B T Hop. Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394414. |
effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. |
2002-12-23 |
2023-08-12 |
rat |
| J W Grimm, Y Shaham, B T Hop. Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394414. |
we also examined whether the time-dependent changes in cocaine seeking correlate with the levels of the dopamine transporter (dat) and tyrosine hydroxylase (th) proteins in the amygdala, nucleus accumbens, prefrontal cortex and orbitofrontal cortex. |
2002-12-23 |
2023-08-12 |
rat |
| Monica L Andersen, Sergio Tufi. Distinct effects of paradoxical sleep deprivation and cocaine administration on sexual behavior in male rats. Addiction biology. vol 7. issue 2. 2002-12-19. PMID:12006221. |
these findings are due probably to psd causing supersensitivity of dopamine (da) receptors exacerbating the cocaine actions on dopaminergic pathways inducing penile erection and ejaculation. |
2002-12-19 |
2023-08-12 |
rat |
| Monica L Andersen, Magda Bignotto, Ricardo Borges Machado, Sergio Tufi. Does paradoxical sleep deprivation and cocaine induce penile erection and ejaculation in old rats? Addiction biology. vol 7. issue 3. 2002-12-19. PMID:12126487. |
the interaction of psd and cocaine probably enhances dopamine transmission in the brain and may elicit penile erection in old rats. |
2002-12-19 |
2023-08-12 |
rat |
| S Ikemot. Ventral striatal anatomy of locomotor activity induced by cocaine, D-amphetamine, dopamine and D1/D2 agonists. Neuroscience. vol 113. issue 4. 2002-11-27. PMID:12182899. |
ventral striatal anatomy of locomotor activity induced by cocaine, d-amphetamine, dopamine and d1/d2 agonists. |
2002-11-27 |
2023-08-12 |
Not clear |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
in the medial prefrontal cortex, repeated cocaine produces tolerance of the extracellular dopamine response to subsequent cocaine injection. |
2002-11-26 |
2023-08-12 |
Not clear |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
these studies characterized the influence of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors on the medial prefrontal cortex dopamine response to acute cocaine, amphetamine and potassium chloride as a first step to assess whether these receptor subtypes may be candidates for mediating dopamine tolerance after repeated cocaine. |
2002-11-26 |
2023-08-12 |
Not clear |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
local medial prefrontal cortex infusion of the 30 microm dose blocked the small increase in dopamine levels elicited by systemic saline injection (maximum of 26%), as well as the much larger increase in response to acute cocaine injection (maximum of 340%). |
2002-11-26 |
2023-08-12 |
Not clear |
| Stanislav R Vorel, Charles R Ashby, Mousumi Paul, Xinhe Liu, Robert Hayes, Jim J Hagan, Derek N Middlemiss, Geoffrey Stemp, Eliot L Gardne. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 21. 2002-11-25. PMID:12417684. |
dopamine d3 receptor is preferentially localized to the mesocorticolimbic dopaminergic system and has been hypothesized to play a role in cocaine addiction. |
2002-11-25 |
2023-08-12 |
rat |
| Stanislav R Vorel, Charles R Ashby, Mousumi Paul, Xinhe Liu, Robert Hayes, Jim J Hagan, Derek N Middlemiss, Geoffrey Stemp, Eliot L Gardne. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 21. 2002-11-25. PMID:12417684. |
these data suggest an important role for d3 receptors in mediating the addictive properties of cocaine and suggest that blockade of dopamine d3 receptors may constitute a new and useful target for prospective pharmacotherapies for cocaine addiction. |
2002-11-25 |
2023-08-12 |
rat |
| Tangui Maurice, Rémi Martin-Fardon, Pascal Romieu, Rae R Matsumot. Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicity. Neuroscience and biobehavioral reviews. vol 26. issue 4. 2002-11-22. PMID:12204195. |
current therapeutic strategies focus on counteracting the cocaine effects directly on the dopamine transporter, through post-synaptic d(1), d(2) or d(3) receptors or through the glutamatergic, serotoninergic, opioid or corticotropin-releasing hormone systems. |
2002-11-22 |
2023-08-12 |
Not clear |
| Joshua A Lile, Drake Morgan, Anne M Birmingham, Zhixia Wang, William L Woolverton, Huw M L Davies, Michael A Nade. The reinforcing efficacy of the dopamine reuptake inhibitor 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388646. |
the time of onset for dopamine transporter (dat) occupancy of the long-acting, high-affinity dat blocker 2beta-propanoyl-3beta-(4-tolyl)-tropane (ptt) was measured using an ex vivo binding assay in rodents and was determined to be significantly longer than for cocaine (30 min versus 2 min). |
2002-11-22 |
2023-08-12 |
monkey |
| Christian P Müller, Maria A De Souza Silva, Gail DePalma, Carlos Tomaz, Robert J Carey, Joseph P Husto. The selective serotonin(1A)-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase. Behavioural brain research. vol 134. issue 1-2. 2002-11-19. PMID:12191821. |
the selective serotonin(1a)-receptor antagonist way 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase. |
2002-11-19 |
2023-08-12 |
rat |