| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heather L Kimmel, F Ivy Carroll, Michael J Kuha. Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 304. issue 1. 2003-01-23. PMID:12490570. |
withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. |
2003-01-23 |
2023-08-12 |
rat |
| Heather L Kimmel, F Ivy Carroll, Michael J Kuha. Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 304. issue 1. 2003-01-23. PMID:12490570. |
several studies have shown that repeated cocaine administration, followed by withdrawal, alters dopamine transporter (dat) levels in the rat. |
2003-01-23 |
2023-08-12 |
rat |
| Heather L Kimmel, F Ivy Carroll, Michael J Kuha. Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 304. issue 1. 2003-01-23. PMID:12490570. |
these initial studies showed that: 1) the half-life of the transporter was between 2 and 3 days in these two brain regions; 2) pretreatment with dopamine d1 and d2 receptor agonists and antagonists over several days differentially altered dat half-lives in the striatum and nucleus accumbens; and 3) pretreatment with cocaine for several days increased the half-life of dat by decreasing the degradation rate constant in both brain regions. |
2003-01-23 |
2023-08-12 |
rat |
| Charles W Bradberr. Dynamics of extracellular dopamine in the acute and chronic actions of cocaine. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 8. issue 4. 2003-01-15. PMID:12194500. |
dynamics of extracellular dopamine in the acute and chronic actions of cocaine. |
2003-01-15 |
2023-08-12 |
rat |
| Charles W Bradberr. Dynamics of extracellular dopamine in the acute and chronic actions of cocaine. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 8. issue 4. 2003-01-15. PMID:12194500. |
this review will provide a brief overview of extracellular dopamine dynamics associated with cocaine. |
2003-01-15 |
2023-08-12 |
rat |
| Charles W Schindler, Gilberto N Carmon. Effects of dopamine agonists and antagonists on locomotor activity in male and female rats. Pharmacology, biochemistry, and behavior. vol 72. issue 4. 2003-01-08. PMID:12062575. |
male and female sprague-dawley rats were treated with cocaine, the specific dopamine uptake inhibitor gbr 12909, the dopamine d1 agonist skf 82958 or the dopamine d2 agonist quinpirole. |
2003-01-08 |
2023-08-12 |
rat |
| Charles W Schindler, Gilberto N Carmon. Effects of dopamine agonists and antagonists on locomotor activity in male and female rats. Pharmacology, biochemistry, and behavior. vol 72. issue 4. 2003-01-08. PMID:12062575. |
these results suggest that the differences between males and females in their locomotor response to cocaine can be at least partially attributed to differences in the function of dopamine d1 and d2 receptors. |
2003-01-08 |
2023-08-12 |
rat |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
the effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
the current experiment evaluated the duration-dependent nature of the induction of behavioral tolerance and changes in dopamine autoreceptor function by continuously administering cocaine for different durations. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
continuous cocaine administration did induce dopamine autoreceptor supersensitivity. |
2003-01-08 |
2023-08-12 |
human |
| George R King, Gail Pinto, Jennifer Konen, Craig Hillburn, Sophie Tran, Wees Love, Rachel Cayse, Gene Castr. The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function. European journal of pharmacology. vol 446. issue 1-3. 2003-01-08. PMID:12098592. |
different continuous cocaine durations may induce differential degrees of dopamine autoreceptor supersensitivity. |
2003-01-08 |
2023-08-12 |
human |
| Ashwin A Patkar, Kevin P Hill, Robert C Sterling, Edward Gottheil, Wade H Berrettini, Stephen P Weinstei. Serum prolactin and response to treatment among cocaine-dependent individuals. Addiction biology. vol 7. issue 1. 2002-12-23. PMID:11900622. |
we investigated whether basal serum prolactin, a measure of central dopamine activity, differed between cocaine-dependent subjects and controls, and whether prolactin levels among cocaine patients were related to their response to treatment. |
2002-12-23 |
2023-08-12 |
human |
| Robert Ranaldi, William L Woolverto. Self-administration of cocaine: scopolamine combinations by rhesus monkeys. Psychopharmacology. vol 161. issue 4. 2002-12-23. PMID:12073173. |
several halogenated analogs of benztropine (bzt) have previously been characterized as potent dopamine (da) uptake inhibitors with diminished reinforcing effects relative to cocaine. |
2002-12-23 |
2023-08-12 |
monkey |
| J W Grimm, Y Shaham, B T Hop. Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394414. |
effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. |
2002-12-23 |
2023-08-12 |
rat |
| J W Grimm, Y Shaham, B T Hop. Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394414. |
we also examined whether the time-dependent changes in cocaine seeking correlate with the levels of the dopamine transporter (dat) and tyrosine hydroxylase (th) proteins in the amygdala, nucleus accumbens, prefrontal cortex and orbitofrontal cortex. |
2002-12-23 |
2023-08-12 |
rat |
| Monica L Andersen, Sergio Tufi. Distinct effects of paradoxical sleep deprivation and cocaine administration on sexual behavior in male rats. Addiction biology. vol 7. issue 2. 2002-12-19. PMID:12006221. |
these findings are due probably to psd causing supersensitivity of dopamine (da) receptors exacerbating the cocaine actions on dopaminergic pathways inducing penile erection and ejaculation. |
2002-12-19 |
2023-08-12 |
rat |
| Monica L Andersen, Magda Bignotto, Ricardo Borges Machado, Sergio Tufi. Does paradoxical sleep deprivation and cocaine induce penile erection and ejaculation in old rats? Addiction biology. vol 7. issue 3. 2002-12-19. PMID:12126487. |
the interaction of psd and cocaine probably enhances dopamine transmission in the brain and may elicit penile erection in old rats. |
2002-12-19 |
2023-08-12 |
rat |
| S Ikemot. Ventral striatal anatomy of locomotor activity induced by cocaine, D-amphetamine, dopamine and D1/D2 agonists. Neuroscience. vol 113. issue 4. 2002-11-27. PMID:12182899. |
ventral striatal anatomy of locomotor activity induced by cocaine, d-amphetamine, dopamine and d1/d2 agonists. |
2002-11-27 |
2023-08-12 |
Not clear |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
in the medial prefrontal cortex, repeated cocaine produces tolerance of the extracellular dopamine response to subsequent cocaine injection. |
2002-11-26 |
2023-08-12 |
Not clear |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
these studies characterized the influence of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors on the medial prefrontal cortex dopamine response to acute cocaine, amphetamine and potassium chloride as a first step to assess whether these receptor subtypes may be candidates for mediating dopamine tolerance after repeated cocaine. |
2002-11-26 |
2023-08-12 |
Not clear |