| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J D Stekete. Intra-ventral tegmental area administration of H7 delays, but does not prevent the development of cocaine-induced sensitization. Brain research bulletin. vol 43. issue 6. 1997-09-23. PMID:9254028. |
in addition, the augmented increase in dopamine in the nucleus accumbens of cocaine-sensitized animals was prevented in animals pretreated with h7 before each of their daily cocaine injections, when tested after a 24 h withdrawal. |
1997-09-23 |
2023-08-12 |
Not clear |
| J D Stekete. Intra-ventral tegmental area administration of H7 delays, but does not prevent the development of cocaine-induced sensitization. Brain research bulletin. vol 43. issue 6. 1997-09-23. PMID:9254028. |
however, when tested after a 1 week withdrawal, animals demonstrated sensitization to both the cocaine-induced increase in motor activity and the cocaine-induced increase in dopamine in the nucleus accumbens regardless of whether they received intra-vta saline or h7 before each of their daily cocaine injections. |
1997-09-23 |
2023-08-12 |
Not clear |
| A E Morgan, B Horan, S L Dewey, C R Ashb. Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 331. issue 1. 1997-09-12. PMID:9274936. |
repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. |
1997-09-12 |
2023-08-12 |
rat |
| A E Morgan, B Horan, S L Dewey, C R Ashb. Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 331. issue 1. 1997-09-12. PMID:9274936. |
cocaine produced a 400% increase in extracellular nucleus accumbens dopamine levels in control rats, whereas in 3,4-methylenedioxymethamphetamine treated rats the increase produced by cocaine was 800%, which was significantly different from controls. |
1997-09-12 |
2023-08-12 |
rat |
| A E Morgan, S P Porter, F A Clarkson, N D Volkow, J S Fowler, S L Dewe. Direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215601. |
using in vivo microdialysis techniques, the effects of rti-55 and/or cocaine on extracellular dopamine (da) concentrations were measured in the nucleus accumbens (nacc) of freely moving rats. |
1997-09-09 |
2023-08-12 |
rat |
| L L Peoples, A J Uzwiak, F Gee, M O Wes. Operant behavior during sessions of intravenous cocaine infusion is necessary and sufficient for phasic firing of single nucleus accumbens neurons. Brain research. vol 757. issue 2. 1997-08-25. PMID:9200758. |
operant behavior during sessions of intravenous cocaine infusion is necessary and sufficient for phasic firing of single nucleus accumbens neurons. |
1997-08-25 |
2023-08-12 |
rat |
| D M Segal, C T Moraes, D C Mas. Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities. Brain research. Molecular brain research. vol 45. issue 2. 1997-08-07. PMID:9149110. |
up-regulation of d3 dopamine receptor mrna in the nucleus accumbens of human cocaine fatalities. |
1997-08-07 |
2023-08-12 |
human |
| D M Segal, C T Moraes, D C Mas. Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities. Brain research. Molecular brain research. vol 45. issue 2. 1997-08-07. PMID:9149110. |
the effects of chronic cocaine use on d3 receptor mrna expression in the human nucleus accumbens was assessed by reverse transcription-polymerase chain reaction. |
1997-08-07 |
2023-08-12 |
human |
| D M Segal, C T Moraes, D C Mas. Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities. Brain research. Molecular brain research. vol 45. issue 2. 1997-08-07. PMID:9149110. |
d3 receptor/cyclophilin mrna ratios in the nucleus accumbens were increased 6-fold in cocaine overdose victims as compared to age-matched and drug-free control subjects. |
1997-08-07 |
2023-08-12 |
human |
| D Lyons, L J Porrin. Dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. Brain research. vol 753. issue 1. 1997-07-17. PMID:9125433. |
dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat. |
1997-07-17 |
2023-08-12 |
rat |
| C Betancur, W Rostène, A Béro. Chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073175. |
chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum. |
1997-07-08 |
2023-08-12 |
rat |
| C Betancur, W Rostène, A Béro. Chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073175. |
repeated administration of cocaine induced a specific increase in the expression of nt mrna in the shell of the nucleus accumbens whereas no changes were observed in the core compartment. |
1997-07-08 |
2023-08-12 |
rat |
| C Betancur, W Rostène, A Béro. Chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073175. |
these findings demonstrate that cocaine affects nt mrna expression in discrete populations of neurons confined to the shell of the nucleus accumbens and dorsomedial and ventrolateral striatum of the rat. |
1997-07-08 |
2023-08-12 |
rat |
| C Betancur, W Rostène, A Béro. Chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum. Brain research. Molecular brain research. vol 44. issue 2. 1997-07-08. PMID:9073175. |
the shell of the nucleus accumbens is a limbic area considered the locus of the reinforcing and locomotor activating properties of cocaine while the dorsal striatum is implicated in the regulation of motor output, and appears to be involved in the stereotypies induced by cocaine. |
1997-07-08 |
2023-08-12 |
rat |
| M S Matell, G R Kin. 5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151358. |
5-ht3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. |
1997-07-07 |
2023-08-12 |
rat |
| M S Matell, G R Kin. 5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151358. |
rats were withdrawn from continuous cocaine administration (40 mg/kg per day cocaine for 14 days) for 7 days, and then slices from the nucleus accumbens obtained. |
1997-07-07 |
2023-08-12 |
rat |
| M S Matell, G R Kin. 5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine. Psychopharmacology. vol 130. issue 3. 1997-07-07. PMID:9151358. |
these results suggest that continuous cocaine administration functionally down-regulates 5-ht3 receptors in the nucleus accumbens. |
1997-07-07 |
2023-08-12 |
rat |
| R P Hammer, Y Egilmez, M W Emmett-Oglesb. Neural mechanisms of tolerance to the effects of cocaine. Behavioural brain research. vol 84. issue 1-2. 1997-06-13. PMID:9079787. |
the mechanism underlying this effect may involve an absolute or relative attenuation of dopamine response to cocaine challenge after frequent or repeated treatment in the nucleus accumbens (nac). |
1997-06-13 |
2023-08-12 |
human |
| R C Pierce, P W Kaliva. Repeated cocaine modifies the mechanism by which amphetamine releases dopamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 9. 1997-05-22. PMID:9096158. |
when the concentration of extracellular dopamine in the nucleus accumbens was elevated by blocking the plasmallemal dopamine transporter with gbr-12909, the augmented increase in extracellular dopamine in rats sensitized to repeated cocaine was blocked by a cam-kii inhibitor. |
1997-05-22 |
2023-08-12 |
rat |
| N D Volkow, G J Wang, J S Fowler, J Logan, S J Gatley, R Hitzemann, A D Chen, S L Dewey, N Pappa. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature. vol 386. issue 6627. 1997-05-22. PMID:9126741. |
this leads to an increase in extracellular dopamine; the reinforcing effect of cocaine is associated with elevated dopamine levels in the nucleus accumbens. |
1997-05-22 |
2023-08-12 |
human |