| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X F Zhang, X T Hu, F J Whit. Whole-cell plasticity in cocaine withdrawal: reduced sodium currents in nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 1. 1998-01-16. PMID:9412525. |
because nucleus accumbens neurons are normally recruited to coordinate response patterns of movement and affect, the decreased excitability during cocaine withdrawal may be related to symptoms such as anergia, anhedonia, and depression. |
1998-01-16 |
2023-08-12 |
rat |
| A J Uzwiak, F X Guyette, M O West, L L People. Neurons in accumbens subterritories of the rat: phasic firing time-locked within seconds of intravenous cocaine self-infusion. Brain research. vol 767. issue 2. 1998-01-15. PMID:9367270. |
individual neurons were recorded extracellularly in the nucleus accumbens (nacc) of rats during cocaine self-administration sessions. |
1998-01-15 |
2023-08-12 |
rat |
| F J White, X T Hu, X F Zhan. Neuroadaptations in nucleus accumbens neurons resulting from repeated cocaine administration. Advances in pharmacology (San Diego, Calif.). vol 42. 1997-11-25. PMID:9328068. |
neuroadaptations in nucleus accumbens neurons resulting from repeated cocaine administration. |
1997-11-25 |
2023-08-12 |
Not clear |
| J K Staley, R B Rothman, K C Rice, J Partilla, D C Mas. Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334398. |
the number of kappa2 receptors in the nucleus accumbens and other limbic brain regions from cocaine fatalities was increased twofold as compared with age-matched and drug-free control subjects. |
1997-11-20 |
2023-08-12 |
human |
| S E Hemby, C Co, T R Koves, J E Smith, S I Dworki. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology. vol 133. issue 1. 1997-11-14. PMID:9335075. |
differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. |
1997-11-14 |
2023-08-12 |
human |
| S E Hemby, C Co, T R Koves, J E Smith, S I Dworki. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology. vol 133. issue 1. 1997-11-14. PMID:9335075. |
studies indicate that nucleus accumbens (nacc) dopamine neurotransmission is involved in the reinforcing and direct effects of cocaine. |
1997-11-14 |
2023-08-12 |
human |
| P M Callahan, R De La Garza, K A Cunningha. Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems. Pharmacology, biochemistry, and behavior. vol 57. issue 3. 1997-10-23. PMID:9218282. |
only infusion of cocaine into the nucleus accumbens has been demonstrated to substitute fully for the systemic effects of this psychostimulant. |
1997-10-23 |
2023-08-12 |
rat |
| P M Callahan, R De La Garza, K A Cunningha. Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems. Pharmacology, biochemistry, and behavior. vol 57. issue 3. 1997-10-23. PMID:9218282. |
6-hydroxydopamine lesions of da terminals in the nucleus accumbens also attenuated the dose-effect curve for systemic administration of cocaine. |
1997-10-23 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
the increase in nucleus accumbens glutamate levels following cocaine (30 mg/kg) was calcium-dependent and was blocked by pretreatment with dopamine antagonists; haloperidol (0.2 mg/kg, i.p. |
1997-10-21 |
2023-08-12 |
rat |
| X B Wang, M Funada, Y Imai, R S Revay, H Ujike, D J Vandenbergh, G R Uh. rGbeta1: a psychostimulant-regulated gene essential for establishing cocaine sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221795. |
antisense oligonucleotide treatments that attenuate rgbeta1 expression in regions including the nucleus accumbens abolish the development of behavioral sensitization when they are administrated during the repeated cocaine exposures that establish sensitization. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
nac-1, a rat brain mrna, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
a combined in situ transcription-pcr amplification strategy was used to isolate a novel mrna, nac-1, from the nucleus accumbens of rats 3 weeks after discontinuing 3 weeks of intravenous cocaine self-administration. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
in rats that self-administered cocaine, levels of nac-1 were increased approximately 50% in the nucleus accumbens but not in the dorsal striatum or hippocampus, when compared with levels from yoked-saline controls. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
in situ hybridization analysis demonstrated increased numbers of nac-1-expressing cells in the nucleus accumbens of rats who had self-administered cocaine. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
nac-1 mrna levels were also increased in the nucleus accumbens 1 week after 6 d of noncontingent cocaine treatments. |
1997-10-03 |
2023-08-12 |
rat |
| X Y Cha, R C Pierce, P W Kalivas, S A Mackle. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278521. |
regulation of nac-1 mrna in the nucleus accumbens demonstrates a long-term effect of cocaine use on cellular function that may be relevant in behavioral sensitization or cocaine self-administration. |
1997-10-03 |
2023-08-12 |
rat |
| b' L Jaworska-Feil, B Budziszewska, W Laso\\xc5\\x8. Effects of repeated cocaine administration on the thyrotropin-releasing hormone level and receptors in the rat brain. Neuropeptides. vol 31. issue 3. 1997-09-29. PMID:9243522.' |
in vitro cocaine (10(-6)-10(-4) m) inhibited the k(+)-stimulated release in a concentration-dependent manner, but had no effect on the basal release of trh from the striatum and nucleus accumbens of naive rats. |
1997-09-29 |
2023-08-12 |
rat |
| b' L Jaworska-Feil, B Budziszewska, W Laso\\xc5\\x8. Effects of repeated cocaine administration on the thyrotropin-releasing hormone level and receptors in the rat brain. Neuropeptides. vol 31. issue 3. 1997-09-29. PMID:9243522.' |
the bmax and affinity of trh receptors following repeated cocaine remained unchanged in the nucleus accumbens. |
1997-09-29 |
2023-08-12 |
rat |
| S L Povlock, J O Schen. A multisubstrate kinetic mechanism of dopamine transport in the nucleus accumbens and its inhibition by cocaine. Journal of neurochemistry. vol 69. issue 3. 1997-09-25. PMID:9282932. |
a multisubstrate kinetic mechanism of dopamine transport in the nucleus accumbens and its inhibition by cocaine. |
1997-09-25 |
2023-08-12 |
Not clear |
| J D Stekete. Intra-ventral tegmental area administration of H7 delays, but does not prevent the development of cocaine-induced sensitization. Brain research bulletin. vol 43. issue 6. 1997-09-23. PMID:9254028. |
pretreatment with h7 in the vta attenuated the acute motor stimulant response to cocaine as well as the cocaine-induced increase in extracellular dopamine in the nucleus accumbens. |
1997-09-23 |
2023-08-12 |
Not clear |