All Relations between cocaine and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Garret D Stuber, Mitchell F Roitman, Paul E M Phillips, Regina M Carelli, R Mark Wightma. Rapid dopamine signaling in the nucleus accumbens during contingent and noncontingent cocaine administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15549053. here, we compare the effects of contingent (response dependent) and noncontingent (response independent) cocaine on rapid dopaminergic signaling in the core of the nucleus accumbens. 2005-05-12 2023-08-12 Not clear
Xiu-Ti Hu, Kerstin Ford, Francis J Whit. Repeated cocaine administration decreases calcineurin (PP2B) but enhances DARPP-32 modulation of sodium currents in rat nucleus accumbens neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15726118. repeated cocaine administration decreases calcineurin (pp2b) but enhances darpp-32 modulation of sodium currents in rat nucleus accumbens neurons. 2005-05-12 2023-08-12 rat
Xiu-Ti Hu, Kerstin Ford, Francis J Whit. Repeated cocaine administration decreases calcineurin (PP2B) but enhances DARPP-32 modulation of sodium currents in rat nucleus accumbens neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15726118. our previous studies have demonstrated that repeated cocaine (coc) administration reduces voltage-sensitive sodium and calcium currents (i(na) or vsscs and i(ca) or vsccs, respectively) in medium spiny nucleus accumbens (nac) neurons of rats. 2005-05-12 2023-08-12 rat
Shane A Perrine, Joseph A Schroeder, Ellen M Unterwal. Behavioral sensitization to binge-pattern cocaine administration is not associated with changes in protein levels of four major G-proteins. Brain research. Molecular brain research. vol 133. issue 2. 2005-05-09. PMID:15710239. results demonstrated that galphaolf mrna expression was significantly reduced in the nucleus accumbens after 1, 3 or 14 days of cocaine, whereas galphai1 mrna was increased following 3, but not 1 or 14 days of cocaine in the caudate putamen, nucleus accumbens and cingulate cortex. 2005-05-09 2023-08-12 rat
Yosuke Morishima, Tsuyoshi Miyakawa, Tomoyuki Furuyashiki, Yasuhiro Tanaka, Hiroshi Mizuma, Shigetada Nakanish. Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 11. 2005-05-09. PMID:15753323. upon in vivo microdialysis analysis after cocaine administration, not only did extracellular levels of dopamine increase but also the response pattern of glutamate release markedly changed in the nucleus accumbens of mglur2-/- ko mice. 2005-05-09 2023-08-12 mouse
Bernard Le Foll, Jorge Diaz, Pierre Sokolof. A single cocaine exposure increases BDNF and D3 receptor expression: implications for drug-conditioning. Neuroreport. vol 16. issue 2. 2005-04-14. PMID:15671872. acute cocaine produced a transient increase in bdnf mrna in the prefrontal cortex, associated with a long-lasting increase in drd3 mrna, and a delayed and long-lasting increase in drd3 protein in the nucleus accumbens. 2005-04-14 2023-08-12 rat
Yolanda Mateo, Evgeny A Budygin, Carrie E John, Matthew L Banks, Sara R Jone. Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens. Journal of neuroscience methods. vol 140. issue 1-2. 2005-04-12. PMID:15589348. cocaine elevates dopamine (da) in the nucleus accumbens (nac) by blocking the uptake of da through the da transporter (dat). 2005-04-12 2023-08-12 mouse
P W Kalivas, N Volkow, J Seaman. Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission. Neuron. vol 45. issue 5. 2005-04-12. PMID:15748840. cellular adaptations in the glutamate projection from the prefrontal cortex (pfc) to the nucleus accumbens have been discovered in rats withdrawn from cocaine that may underlie these cardinal features of addiction. 2005-04-12 2023-08-12 rat
Rita A Fuchs, K Allison Evans, Macon C Parker, Ronald E Se. Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15138757. differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats. 2005-03-01 2023-08-12 rat
Rita A Fuchs, K Allison Evans, Macon C Parker, Ronald E Se. Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15138757. the nucleus accumbens (nac) is theorized to be a critical element of the neural circuitry that mediates relapse to cocaine seeking. 2005-03-01 2023-08-12 rat
Giuliano Grignaschi, Silvia Burbassi, Eleonora Zennaro, Caterina Bendotti, Luigi Cerv. A single high dose of cocaine induces behavioural sensitization and modifies mRNA encoding GluR1 and GAP-43 in rats. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548228. single dose of 20 but not 10 mg/kg cocaine 48 h before scheduled death significantly enhanced glur1 and gap-43 mrna expression in the nucleus accumbens (nac), both shell and core subregions, and ventral tegmental area (vta). 2005-03-01 2023-08-12 rat
Yolanda Mateo, Evgeny A Budygin, Drake Morgan, David C S Roberts, Sara R Jone. Fast onset of dopamine uptake inhibition by intravenous cocaine. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548229. in vivo voltammetry in the nucleus accumbens of anesthetized rats was used to investigate the time of onset of dopamine uptake inhibition by intravenous cocaine. 2005-03-01 2023-08-12 rat
Nobuyoshi Suto, Lauren M Tanabe, Jennifer D Austin, Elizabeth Creekmore, Chauchau T Pham, Paul Vezin. Previous exposure to psychostimulants enhances the reinstatement of cocaine seeking by nucleus accumbens AMPA. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15266353. previous exposure to psychostimulants enhances the reinstatement of cocaine seeking by nucleus accumbens ampa. 2005-02-14 2023-08-12 rat
Nobuyoshi Suto, Lauren M Tanabe, Jennifer D Austin, Elizabeth Creekmore, Chauchau T Pham, Paul Vezin. Previous exposure to psychostimulants enhances the reinstatement of cocaine seeking by nucleus accumbens AMPA. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15266353. the effect of previous exposure to psychostimulants on the subsequent self-administration of cocaine as well as reinstatement of this behavior by priming infusions of ampa into the nucleus accumbens (nacc) was examined. 2005-02-14 2023-08-12 rat
Lawrence Fourgeaud, Susana Mato, Delphine Bouchet, Agnès Hémar, Paul F Worley, Olivier J Manzon. A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 31. 2005-02-07. PMID:15295029. a single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. 2005-02-07 2023-08-12 mouse
Peter W Kalivas, Karen K Szumlinski, Paul Worle. Homer2 gene deletion in mice produces a phenotype similar to chronic cocaine treated rats. Neurotoxicity research. vol 6. issue 5. 2005-01-26. PMID:15545022. homer2 deletion also caused mice to show reduced basal extracellular glutamate in the nucleus accumbens and a sensitized increase in extracellular glutamate in response to a cocaine injection. 2005-01-26 2023-08-12 mouse
L E O'Dell, L H Parson. Serotonin1B receptors in the ventral tegmental area modulate cocaine-induced increases in nucleus accumbens dopamine levels. The Journal of pharmacology and experimental therapeutics. vol 311. issue 2. 2005-01-25. PMID:15226384. this study used dual probe microdialysis to investigate whether activation of serotonin(1b) (5-ht(1b)) receptors in the ventral tegmental area (vta) alters the ability of peripherally administered cocaine to elevate dopamine (da) levels in the ipsilateral nucleus accumbens (nacc) of drug-naive wistar rats. 2005-01-25 2023-08-12 rat
Heather Trantham-Davidson, Antonieta Lavi. Acute cocaine administration depresses cortical activity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15138440. indeed, there is considerable evidence that acute administration of cocaine alters cellular processes at the level of the nucleus accumbens and the ventral tegmental area (vta). 2005-01-11 2023-08-12 Not clear
David W Self, Kwang-Ho Choi, Diana Simmons, John R Walker, Cynthia S Smagul. Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 5. 2005-01-06. PMID:15466321. extinction training normalizes tyrosine hydroxylase levels in the nucleus accumbens (nac) shell, an effect that could help ameliorate dysphoria and depression associated with withdrawal from chronic cocaine use. 2005-01-06 2023-08-12 rat
Yilin Li, Martin J Acerbo, Terry E Robinso. The induction of behavioural sensitization is associated with cocaine-induced structural plasticity in the core (but not shell) of the nucleus accumbens. The European journal of neuroscience. vol 20. issue 6. 2004-12-20. PMID:15355332. repeated exposure to cocaine increases the density of dendritic spines on medium spiny neurons in the nucleus accumbens (acb) and pyramidal cells in the medial prefrontal cortex (mpfc). 2004-12-20 2023-08-12 rat