| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dawn N Albertson, Barb Pruetz, Carl J Schmidt, Donald M Kuhn, Gregory Kapatos, Michael J Banno. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009677. |
gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. |
2004-03-30 |
2023-08-12 |
human |
| Dawn N Albertson, Barb Pruetz, Carl J Schmidt, Donald M Kuhn, Gregory Kapatos, Michael J Banno. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009677. |
this study was undertaken to identify those transcripts differentially regulated in the nucleus accumbens of human cocaine abusers. |
2004-03-30 |
2023-08-12 |
human |
| Dawn N Albertson, Barb Pruetz, Carl J Schmidt, Donald M Kuhn, Gregory Kapatos, Michael J Banno. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009677. |
as expected, gene expression of cocaine- and amphetamine-regulated transcript (cart) was increased in the nucleus accumbens of cocaine abusers. |
2004-03-30 |
2023-08-12 |
human |
| Dawn N Albertson, Barb Pruetz, Carl J Schmidt, Donald M Kuhn, Gregory Kapatos, Michael J Banno. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009677. |
in addition, immunohistochemical experiments revealed a decrease in the number of mbp-immunoreactive oligodendrocytes present in the nucleus accumbens and surrounding white matter of cocaine abusers. |
2004-03-30 |
2023-08-12 |
human |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
a single dose of cocaine did not alter the density of presynaptic nerve terminal glutamate immunoreactivity in the nucleus accumbens (nac) or ventral tegmental area (vta). |
2004-03-24 |
2023-08-12 |
rat |
| Cynthia A Crawford, Fiona Y Choi, Jodi L Kohutek, Shelly T Yoshida, Sanders A McDougal. Changes in PKA activity and Gs alpha and Golf alpha levels after amphetamine- and cocaine-induced behavioral sensitization. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696012. |
studies relevant to this hypothesis have provided conflicting evidence, however, because repeated cocaine and amphetamine treatment has been alternately reported to either increase or decrease protein kinase a (pka) activity in the nucleus accumbens and dorsal striatum. |
2004-03-24 |
2023-08-12 |
rat |
| Cynthia A Crawford, Fiona Y Choi, Jodi L Kohutek, Shelly T Yoshida, Sanders A McDougal. Changes in PKA activity and Gs alpha and Golf alpha levels after amphetamine- and cocaine-induced behavioral sensitization. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696012. |
g(salpha) levels were unaffected by psychostimulant exposure, while g(olfalpha) levels in the nucleus accumbens declined significantly after amphetamine or cocaine pretreatment. |
2004-03-24 |
2023-08-12 |
rat |
| Yun Liu, Hai-Rong He, Jian-Hua Ding, Bing Gu, Hai Wang, Gang H. Iptkalim inhibits cocaine challenge-induced enhancement of dopamine levels in nucleus accumbens and striatum of rats by up-regulating Kir6.1 and Kir6.2 mRNA expression. Acta pharmacologica Sinica. vol 24. issue 6. 2004-03-22. PMID:12791178. |
iptkalim inhibits cocaine challenge-induced enhancement of dopamine levels in nucleus accumbens and striatum of rats by up-regulating kir6.1 and kir6.2 mrna expression. |
2004-03-22 |
2023-08-12 |
rat |
| Yun Liu, Hai-Rong He, Jian-Hua Ding, Bing Gu, Hai Wang, Gang H. Iptkalim inhibits cocaine challenge-induced enhancement of dopamine levels in nucleus accumbens and striatum of rats by up-regulating Kir6.1 and Kir6.2 mRNA expression. Acta pharmacologica Sinica. vol 24. issue 6. 2004-03-22. PMID:12791178. |
to investigate the effect and mechanism of novel atp-sensitive potassium channel opener (kco) iptkalim (ipt) on acute and cocaine challenge-induced alterations in the levels of dopamine (da) and glutamate (glu) from nucleus accumbens (nac), striatum, and prefrontal cortex (pfc) in rats. |
2004-03-22 |
2023-08-12 |
rat |
| Sara Jane Ward, Thomas J Martin, David C S Robert. Beta-funaltrexamine affects cocaine self-administration in rats responding on a progressive ratio schedule of reinforcement. Pharmacology, biochemistry, and behavior. vol 75. issue 2. 2004-03-17. PMID:12873620. |
microinjection of betafna into the ventral tegmental area (vta) or the nucleus accumbens (nacc) had no effect on cocaine self-administration under a fixed ratio (fr) schedule of reinforcement. |
2004-03-17 |
2023-08-12 |
rat |
| Aiko Ikegami, Christine L Duvauchell. Nucleus accumbens and medial prefrontal cortex dopaminergic response to self-administered cocaine in naive rats. Neuroscience letters. vol 354. issue 3. 2004-03-08. PMID:14700732. |
nucleus accumbens and medial prefrontal cortex dopaminergic response to self-administered cocaine in naive rats. |
2004-03-08 |
2023-08-12 |
rat |
| Aiko Ikegami, Christine L Duvauchell. Nucleus accumbens and medial prefrontal cortex dopaminergic response to self-administered cocaine in naive rats. Neuroscience letters. vol 354. issue 3. 2004-03-08. PMID:14700732. |
cocaine reinforcement is strongly associated with increased nucleus accumbens dopamine (nacc da). |
2004-03-08 |
2023-08-12 |
rat |
| Wilfrid Noel Raby, Siobhan Coomaraswam. Gabapentin reduces cocaine use among addicts from a community clinic sample. The Journal of clinical psychiatry. vol 65. issue 1. 2004-03-02. PMID:14744174. |
gabapentin was hypothesized to reduce cocaine use by restoring inhibitory gabaergic feedback on ascending dopaminergic projections to nucleus accumbens neurons. |
2004-03-02 |
2023-08-12 |
Not clear |
| D A Baker, H Shen, P W Kaliva. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino acids. vol 23. issue 1-3. 2004-02-26. PMID:12373531. |
repeated administration of cocaine lowers the basal extracellular levels of glutamate in the nucleus accumbens as measured by microdialysis. |
2004-02-26 |
2023-08-12 |
Not clear |
| Patricia A Broderick, Omotola Hope, Catherine Okonji, David N Rahni, Yueping Zho. Clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687870. |
clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. |
2004-02-18 |
2023-08-12 |
rat |
| M Behnam Ghasemzadeh, Lindsay K Permenter, Russel W Lake, Peter W Kaliva. Nucleus accumbens Homer proteins regulate behavioral sensitization to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684470. |
nucleus accumbens homer proteins regulate behavioral sensitization to cocaine. |
2004-02-13 |
2023-08-12 |
Not clear |
| Joshua M Gulley, Brian R Hoover, Gaynor A Larson, Nancy R Zahnise. Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12902997. |
in rats classified as lcrs or hcrs after 10 mg/kg cocaine injection, we found no differences in (1) novelty-induced locomotion, (2) cocaine levels in dorsal striatum or nucleus accumbens (nac), (3) dat number or affinity in nac, or (4) dat affinity for cocaine in nac. |
2004-02-10 |
2023-08-12 |
rat |
| Francesco Leri, Joseph Flores, Heshmat Rajabi, Jane Stewar. Effects of cocaine in rats exposed to heroin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12955094. |
in response to cocaine, however, da activity in the acb was significantly lower in rats withdrawn from the highest dose of heroin. |
2004-02-10 |
2023-08-12 |
rat |
| Jason N Jaworski, Marie A Kozel, Kelly B Philpot, Michael J Kuha. Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaine-induced locomotor activity. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14551286. |
in summary, these data suggest that cart peptides in the nucleus accumbens would tend to oppose the actions of cocaine. |
2004-01-29 |
2023-08-12 |
rat |