| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aiko Ikegami, Christine L Duvauchell. Nucleus accumbens and medial prefrontal cortex dopaminergic response to self-administered cocaine in naive rats. Neuroscience letters. vol 354. issue 3. 2004-03-08. PMID:14700732. |
cocaine reinforcement is strongly associated with increased nucleus accumbens dopamine (nacc da). |
2004-03-08 |
2023-08-12 |
rat |
| Wilfrid Noel Raby, Siobhan Coomaraswam. Gabapentin reduces cocaine use among addicts from a community clinic sample. The Journal of clinical psychiatry. vol 65. issue 1. 2004-03-02. PMID:14744174. |
gabapentin was hypothesized to reduce cocaine use by restoring inhibitory gabaergic feedback on ascending dopaminergic projections to nucleus accumbens neurons. |
2004-03-02 |
2023-08-12 |
Not clear |
| D A Baker, H Shen, P W Kaliva. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino acids. vol 23. issue 1-3. 2004-02-26. PMID:12373531. |
repeated administration of cocaine lowers the basal extracellular levels of glutamate in the nucleus accumbens as measured by microdialysis. |
2004-02-26 |
2023-08-12 |
Not clear |
| Patricia A Broderick, Omotola Hope, Catherine Okonji, David N Rahni, Yueping Zho. Clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687870. |
clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. |
2004-02-18 |
2023-08-12 |
rat |
| M Behnam Ghasemzadeh, Lindsay K Permenter, Russel W Lake, Peter W Kaliva. Nucleus accumbens Homer proteins regulate behavioral sensitization to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684470. |
nucleus accumbens homer proteins regulate behavioral sensitization to cocaine. |
2004-02-13 |
2023-08-12 |
Not clear |
| Joshua M Gulley, Brian R Hoover, Gaynor A Larson, Nancy R Zahnise. Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12902997. |
in rats classified as lcrs or hcrs after 10 mg/kg cocaine injection, we found no differences in (1) novelty-induced locomotion, (2) cocaine levels in dorsal striatum or nucleus accumbens (nac), (3) dat number or affinity in nac, or (4) dat affinity for cocaine in nac. |
2004-02-10 |
2023-08-12 |
rat |
| Francesco Leri, Joseph Flores, Heshmat Rajabi, Jane Stewar. Effects of cocaine in rats exposed to heroin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12955094. |
in response to cocaine, however, da activity in the acb was significantly lower in rats withdrawn from the highest dose of heroin. |
2004-02-10 |
2023-08-12 |
rat |
| Jason N Jaworski, Marie A Kozel, Kelly B Philpot, Michael J Kuha. Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaine-induced locomotor activity. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14551286. |
in summary, these data suggest that cart peptides in the nucleus accumbens would tend to oppose the actions of cocaine. |
2004-01-29 |
2023-08-12 |
rat |
| Shigenobu Toda, Luis F Alguacil, Peter W Kaliva. Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens. Journal of neurochemistry. vol 87. issue 6. 2004-01-26. PMID:14713303. |
repeated cocaine administration changes the function and subcellular distribution of adenosine a1 receptor in the rat nucleus accumbens. |
2004-01-26 |
2023-08-12 |
rat |
| Shigenobu Toda, Luis F Alguacil, Peter W Kaliva. Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens. Journal of neurochemistry. vol 87. issue 6. 2004-01-26. PMID:14713303. |
adenosine a1 receptor (a1) protein and mrna is increased in the nucleus accumbens following repeated cocaine treatment. |
2004-01-26 |
2023-08-12 |
rat |
| Shigenobu Toda, Luis F Alguacil, Peter W Kaliva. Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens. Journal of neurochemistry. vol 87. issue 6. 2004-01-26. PMID:14713303. |
these data suggest that the sorting and recycling of a1 receptors is dysregulated in the nucleus accumbens as the consequence of repeated cocaine administration. |
2004-01-26 |
2023-08-12 |
rat |
| P J Wang, Michael Stromberg, Stephen Replenski, Alexander Snyder-Mackler, Scott A Mackle. The relationship between cocaine-induced increases in NAC1 and behavioral sensitization. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759112. |
nac1, a member of the poz/btb transcription factor family, exhibited increased mrna levels in the nucleus accumbens of the rat weeks after cocaine use. |
2004-01-07 |
2023-08-12 |
rat |
| P J Wang, Michael Stromberg, Stephen Replenski, Alexander Snyder-Mackler, Scott A Mackle. The relationship between cocaine-induced increases in NAC1 and behavioral sensitization. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759112. |
there was significantly greater expression of the long isoform, lnac1 (cocaine 1.341+/-0.641; saline 1+/-0.321; p=.044), and the short isoform, snac1 (cocaine 3.038+/-2.816; saline 1+/-0.720; p=.001), in the nucleus accumbens of cocaine-treated rats. |
2004-01-07 |
2023-08-12 |
rat |
| Stefan D Schlussman, Yong Zhang, Saul Kane, Campbell L Stewart, Ann Ho, Mary Jeanne Kree. Locomotion, stereotypy, and dopamine D1 receptors after chronic "binge" cocaine in C57BL/6J and 129/J mice. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759120. |
dopamine d(1) receptor binding in the nucleus accumbens and olfactory tubercle did not differ between strains and was not affected by chronic binge cocaine. |
2004-01-07 |
2023-08-12 |
mouse |
| Yong Zhang, Stefan D Schlussman, Ann Ho, Mary Jeanne Kree. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515336. |
effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of c57bl/6j and 129/j mice. |
2004-01-06 |
2023-08-12 |
mouse |
| Yong Zhang, Stefan D Schlussman, Ann Ho, Mary Jeanne Kree. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515336. |
in vivo microdialysis was used to measure the effect of chronic "binge" pattern cocaine administration on basal and cocaine-induced dopamine levels in the caudate putamen and nucleus accumbens of c57bl/6j and 129/j mice. |
2004-01-06 |
2023-08-12 |
mouse |
| Yong Zhang, Stefan D Schlussman, Ann Ho, Mary Jeanne Kree. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515336. |
mice were implanted with a guide cannula in the caudate putamen or nucleus accumbens and after 4 days recovery, one group received "binge" pattern cocaine administration for 13 days (15 mg/kg x 3, i.p. |
2004-01-06 |
2023-08-12 |
mouse |
| Yong Zhang, Stefan D Schlussman, Ann Ho, Mary Jeanne Kree. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515336. |
however, when expressed as percent increase over baseline, the dopamine response to cocaine in the nucleus accumbens was significantly higher in mice that received chronic than in mice that received acute cocaine administration. |
2004-01-06 |
2023-08-12 |
mouse |
| Yong Zhang, Stefan D Schlussman, Ann Ho, Mary Jeanne Kree. Effect of chronic "binge cocaine" on basal levels and cocaine-induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice. Synapse (New York, N.Y.). vol 50. issue 3. 2004-01-06. PMID:14515336. |
chronic cocaine administration led to a lowering of both basal dopamine and the absolute levels of cocaine-induced increases of dopamine in the two brain regions, but enhanced the percent increases over the baseline in response to cocaine in the nucleus accumbens of both mouse strains. |
2004-01-06 |
2023-08-12 |
mouse |
| Regina M Carelli, Joyce Wondolowsk. Selective encoding of cocaine versus natural rewards by nucleus accumbens neurons is not related to chronic drug exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 35. 2003-12-23. PMID:14657180. |
selective encoding of cocaine versus natural rewards by nucleus accumbens neurons is not related to chronic drug exposure. |
2003-12-23 |
2023-08-12 |
Not clear |