| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeffrey L Barr, Elena Deliu, G Cristina Brailoiu, Pingwei Zhao, Guang Yan, Mary E Abood, Ellen M Unterwald, Eugen Brailoi. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell calcium. vol 58. issue 2. 2016-04-19. PMID:26077147. |
mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. |
2016-04-19 |
2023-08-13 |
Not clear |
| Jeffrey L Barr, Elena Deliu, G Cristina Brailoiu, Pingwei Zhao, Guang Yan, Mary E Abood, Ellen M Unterwald, Eugen Brailoi. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell calcium. vol 58. issue 2. 2016-04-19. PMID:26077147. |
cocaine promotes addictive behavior primarily by blocking the dopamine transporter, thus increasing dopamine transmission in the nucleus accumbens (nacc); however, additional mechanisms are continually emerging. |
2016-04-19 |
2023-08-13 |
Not clear |
| Kathryn B Holroyd, Martin F Adrover, Robert L Fuino, Roland Bock, Alanna R Kaplan, Christina M Gremel, Marcelo Rubinstein, Veronica A Alvare. Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 6. 2016-03-29. PMID:25547712. |
here, we show that selective loss of d2 autoreceptors impairs the feedback inhibition of da release and amplifies the effect of cocaine on da transmission in the nucleus accumbens (nac) in vitro. |
2016-03-29 |
2023-08-13 |
mouse |
| Ivan Diamond, Lina Ya. From Ancient Chinese Medicine to a Novel Approach to Treat Cocaine Addiction. CNS & neurological disorders drug targets. vol 14. issue 6. 2016-03-23. PMID:26022266. |
we have synthesized highly selective novel aldh2 inhibitors (aldh2i) that block alcohol- and cocaine cue-induced surges in nucleus accumbens (nac) da and prevent reinstatement of alcohol heavy drinking, cocaine self-administration and reinstatement of cocaine relapse-like behavior. |
2016-03-23 |
2023-08-13 |
human |
| Kevin R Coffey, David J Barker, Nick Gayliard, Julianna M Kulik, Anthony P Pawlak, Joshua P Stamos, Mark O Wes. Electrophysiological evidence of alterations to the nucleus accumbens and dorsolateral striatum during chronic cocaine self-administration. The European journal of neuroscience. vol 41. issue 12. 2016-03-16. PMID:25952463. |
electrophysiological evidence of alterations to the nucleus accumbens and dorsolateral striatum during chronic cocaine self-administration. |
2016-03-16 |
2023-08-13 |
Not clear |
| Eun Young Jang, Yeon-Hee Ryu, Bong Hyo Lee, Su-Chan Chang, Mi Jin Yeo, Sang Hyun Kim, Ryan J Folsom, Nathan D Schilaty, Kwang Joong Kim, Chae Ha Yang, Scott C Steffensen, Hee Young Ki. Involvement of reactive oxygen species in cocaine-taking behaviors in rats. Addiction biology. vol 20. issue 4. 2016-02-29. PMID:24975938. |
the aim of this study was to evaluate cocaine enhancement of brain metabolic activity and the effects of ros scavengers on cocaine self-administration behavior, cocaine-induced ros production in the nucleus accumbens (nac) and cocaine enhancement of da release in the nac. |
2016-02-29 |
2023-08-13 |
rat |
| Yvonne E Ogbonmwan, Natale R Sciolino, Jessica L Groves-Chapman, Kimberly G Freeman, Jason P Schroeder, Gaylen L Edwards, Philip V Holmes, David Weinshenke. The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex. Addiction biology. vol 20. issue 4. 2016-02-29. PMID:25053279. |
we found that galnon attenuated cocaine-induced motor activity, reinstatement and da overflow in the frontal cortex at a dose that did not reduce baseline motor activity, stable self-administration of cocaine, baseline extracellular da levels or cocaine-induced da overflow in the nucleus accumbens (nac). |
2016-02-29 |
2023-08-13 |
rat |
| Martin Grosshans, Jochen Mutschler, Falk Kiefe. Treatment of cocaine craving with as-needed nalmefene, a partial κ opioid receptor agonist: first clinical experience. International clinical psychopharmacology. vol 30. issue 4. 2016-02-26. PMID:25647453. |
it should be noted that patients addicted to cocaine show a considerable increase in κ receptors in the nucleus accumbens. |
2016-02-26 |
2023-08-13 |
Not clear |
| Gregory C Sartor, Samuel K Powell, Shaun P Brothers, Claes Wahlested. Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 45. 2016-02-22. PMID:26558777. |
of the bet proteins, brd4, but not brd2 or brd3, was significantly elevated in the nucleus accumbens (nac) of mice and rats following repeated cocaine injections and self-administration. |
2016-02-22 |
2023-08-13 |
mouse |
| Danielle Zheng, Soledad Cabeza de Vaca, Zachary Jurkowski, Kenneth D Car. Nucleus accumbens AMPA receptor involvement in cocaine-conditioned place preference under different dietary conditions in rats. Psychopharmacology. vol 232. issue 13. 2016-02-02. PMID:25589145. |
when ad libitum-fed (al) rats undergo cocaine place preference conditioning (cpp) but are switched to food restriction (fr) for testing, cpp is enhanced and preference scores correlate with phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glua1 at ser845 in nucleus accumbens (nac) core. |
2016-02-02 |
2023-08-13 |
rat |
| Yoko H Ohnishi, Yoshinori N Ohnishi, Takanori Nakamura, Mizuki Ohno, Pamela J Kennedy, Yasuyuki Ohkawa, Ohkawa Yasuyuki, Akinori Nishi, Rachael Neve, Teruhisa Tsuzuki, Eric J Nestle. PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. PloS one. vol 10. issue 5. 2016-02-02. PMID:25962134. |
psmc5, a 19s proteasomal atpase, regulates cocaine action in the nucleus accumbens. |
2016-02-02 |
2023-08-13 |
Not clear |
| Yoko H Ohnishi, Yoshinori N Ohnishi, Takanori Nakamura, Mizuki Ohno, Pamela J Kennedy, Yasuyuki Ohkawa, Ohkawa Yasuyuki, Akinori Nishi, Rachael Neve, Teruhisa Tsuzuki, Eric J Nestle. PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. PloS one. vol 10. issue 5. 2016-02-02. PMID:25962134. |
Δfosb is a stable transcription factor which accumulates in the nucleus accumbens (nac), a key part of the brain's reward circuitry, in response to chronic exposure to cocaine or other drugs of abuse. |
2016-02-02 |
2023-08-13 |
Not clear |
| Yijing Li, Yanfang Zuo, Peng Yu, Xingjie Ping, Cailian Cu. Role of basolateral amygdala dopamine D2 receptors in impulsive choice in acute cocaine-treated rats. Behavioural brain research. vol 287. 2016-01-19. PMID:25823760. |
moreover, bilateral microinjection of eticlopride (1 μg/side) into the basolateral amygdala (bla) but not the nucleus accumbens (nac) core reversed the inhibitory effect of acute cocaine on impulsive choice. |
2016-01-19 |
2023-08-13 |
rat |
| Casey E O'Neill, Sophia C Levis, Drew C Schreiner, Jose Amat, Steven F Maier, Ryan K Bachtel. Effects of adolescent caffeine consumption on cocaine sensitivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25328052. |
we identified the effects of adolescent caffeine consumption on cocaine sensitivity and determined neurobiological changes within the nucleus accumbens (nac) that may underlie caffeine-induced hypersensitivity to cocaine. |
2016-01-05 |
2023-08-13 |
rat |
| Yan Li, Ruiming Zhu, Wenjing Wang, Dengqi Fu, Jing Hou, Sen Ji, Bo Chen, Zhengtao Hu, Xue Shao, Xuri Yu, Qian Zhao, Baolai Zhang, Changman Du, Qian Bu, Chunyan Hu, Yun Tang, Lei Zhong, Shengyong Yang, Yinglan Zhao, Xiaobo Ce. Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 37. 2016-01-04. PMID:26377474. |
arginine methyltransferase 1 in the nucleus accumbens regulates behavioral effects of cocaine. |
2016-01-04 |
2023-08-13 |
mouse |
| Yan Li, Ruiming Zhu, Wenjing Wang, Dengqi Fu, Jing Hou, Sen Ji, Bo Chen, Zhengtao Hu, Xue Shao, Xuri Yu, Qian Zhao, Baolai Zhang, Changman Du, Qian Bu, Chunyan Hu, Yun Tang, Lei Zhong, Shengyong Yang, Yinglan Zhao, Xiaobo Ce. Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 37. 2016-01-04. PMID:26377474. |
here, we demonstrate that repeated noncontingent cocaine injections increase prmt1 activity in the nucleus accumbens (nac) of c57bl/6 mice. |
2016-01-04 |
2023-08-13 |
mouse |
| Adeline Cathala, Céline Devroye, Marlène Maitre, Pier Vincenzo Piazza, Djoher Nora Abrous, Jean-Michel Revest, Umberto Spampinat. Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24661380. |
serotonin2c receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine. |
2016-01-01 |
2023-08-12 |
Not clear |
| Bo Chen, Yao Wang, Xiaodong Liu, Zheng Liu, Yan Dong, Yanhua H Huan. Sleep Regulates Incubation of Cocaine Craving. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 39. 2015-12-28. PMID:26424879. |
incubation of cocaine craving is partially mediated by progressive accumulation of calcium-permeable ampa receptors (cp-ampars) in the nucleus accumbens (nac). |
2015-12-28 |
2023-08-13 |
rat |
| Bo Chen, Yao Wang, Xiaodong Liu, Zheng Liu, Yan Dong, Yanhua H Huan. Sleep Regulates Incubation of Cocaine Craving. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 39. 2015-12-28. PMID:26424879. |
we further demonstrate that glutamatergic synapses in the nucleus accumbens are potential neuronal targets for sleep intervention to influence cocaine craving after withdrawal. |
2015-12-28 |
2023-08-13 |
rat |
| Pavel I Ortinski, Lisa A Briand, R Christopher Pierce, Heath D Schmid. Cocaine-seeking is associated with PKC-dependent reduction of excitatory signaling in accumbens shell D2 dopamine receptor-expressing neurons. Neuropharmacology. vol 92. 2015-12-01. PMID:25596492. |
stimulation of d1-like dopamine receptors (d1drs) or d2-like dopamine receptors (d2drs) in the nucleus accumbens (nac) shell reinstates cocaine seeking in rats, an animal model of relapse. |
2015-12-01 |
2023-08-13 |
mouse |