| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Suzuki, K Hirooka, K Kanda, H Uesaka, H Hirooka, K Furusaw. Characterization of the neurochemical effects of N-[2-(1-azabicyclo[3,3,0]octan-5-yl)ethyl]2-nitroaniline fumarate (SK-946) as a cognition activator. Biological & pharmaceutical bulletin. vol 21. issue 7. 1998-10-22. PMID:9703253. |
using in vivo microdialysis, it was found that relatively low concentrations (<10(-7) m) of sk-946 increased acetylcholine release and decreased choline content in that hippocampal area in rats. |
1998-10-22 |
2023-08-12 |
human |
| R Goldbach, C Allgaier, B Heimrich, R Jackisc. Postnatal development of muscarinic autoreceptors modulating acetylcholine release in the septohippocampal cholinergic system. I. Axon terminal region: hippocampus. Brain research. Developmental brain research. vol 108. issue 1-2. 1998-10-21. PMID:9693780. |
to this end, hippocampal slices (350 microns thick) from rats of various postnatal ages (postnatal day 3 [p3] to p16) were preincubated with [3h]choline and stimulated twice (s1, s2: 360 pulses, 2 ms, 3 hz, 60 ma) during superfusion with physiological buffer containing hemicholinium-3 (10 microm). |
1998-10-21 |
2023-08-12 |
rat |
| R Goldbach, C Allgaier, B Heimrich, R Jackisc. Postnatal development of muscarinic autoreceptors modulating acetylcholine release in the septohippocampal cholinergic system. I. Axon terminal region: hippocampus. Brain research. Developmental brain research. vol 108. issue 1-2. 1998-10-21. PMID:9693780. |
in hippocampal slices preincubated with [3h]choline, the electrically evoked overflow of 3h at s1 increased from 0.11 (p3) to 0.81% of tissue 3h (p16), the latter value being still much lower than that of hippocampal slices from adult rats (2.89% of tissue 3h). |
1998-10-21 |
2023-08-12 |
rat |
| b' Z Kristofikov\\xc3\\xa1, J Klaschka, H Tejkalov\\xc3\\xa. Effects of K+-depolarization, arachidonic acid, ethanol, and aging on the high-affinity choline transport in rat hippocampus. Neurochemical research. vol 23. issue 7. 1998-10-09. PMID:9690733.' |
effects of k+-depolarization, arachidonic acid, ethanol, and aging on the high-affinity choline transport in rat hippocampus. |
1998-10-09 |
2023-08-12 |
rat |
| b' Z Kristofikov\\xc3\\xa1, J Klaschka, H Tejkalov\\xc3\\xa. Effects of K+-depolarization, arachidonic acid, ethanol, and aging on the high-affinity choline transport in rat hippocampus. Neurochemical research. vol 23. issue 7. 1998-10-09. PMID:9690733.' |
the na+-dependent high-affinity choline uptake (hacu) transport and the [3h]hemicholinium-3 ([3h]hc-3) specific binding were measured on hippocampal synaptosomes of young (3-6 months) and old (22 months) wistar rats. |
1998-10-09 |
2023-08-12 |
rat |
| C Erb, J Klei. Enhancement of brain choline levels by nicotinamide: mechanism of action. Neuroscience letters. vol 249. issue 2-3. 1998-09-30. PMID:9682829. |
in hippocampal slices, nicotinamide (1-10 mm) induced choline release in a calcium- and mepacrine-sensitive manner and, in [3h]choline-labelled slices, increased the levels of [3h]lyso-phosphatidylcholine and [3h]glycerophosphocholine. |
1998-09-30 |
2023-08-12 |
Not clear |
| C D Albright, A Y Tsai, M H Mar, S H Zeise. Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochemical research. vol 23. issue 5. 1998-06-19. PMID:9566615. |
choline availability modulates the expression of tgfbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. |
1998-06-19 |
2023-08-12 |
rat |
| C D Albright, A Y Tsai, M H Mar, S H Zeise. Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochemical research. vol 23. issue 5. 1998-06-19. PMID:9566615. |
choline availability influences long-term memory in concert with changes in the spatial organization and morphology of septal neurons, however little is known concerning the effects of choline on the hippocampus, a region of the brain also important for memory performance. |
1998-06-19 |
2023-08-12 |
rat |
| C D Albright, A Y Tsai, M H Mar, S H Zeise. Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochemical research. vol 23. issue 5. 1998-06-19. PMID:9566615. |
gap43 and nse were localized to peripheral nervous tissue but not hippocampus, indicating that the maturation of axons and neurite outgrowth in embryonic hippocampus were unaffected by the availability of choline in the diet. |
1998-06-19 |
2023-08-12 |
rat |
| C D Albright, A Y Tsai, M H Mar, S H Zeise. Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochemical research. vol 23. issue 5. 1998-06-19. PMID:9566615. |
these data suggest that the availability of choline affects the differentiation of specific regions of developing hippocampus. |
1998-06-19 |
2023-08-12 |
rat |
| R F Deicken, L Zhou, N Schuff, G Fein, M W Weine. Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy. Biological psychiatry. vol 43. issue 7. 1998-06-08. PMID:9547926. |
this study measured naa, choline, and creatine in the hippocampal region of patients with schizophrenia using in vivo proton magnetic resonance spectroscopic imaging (1h mrsi). |
1998-06-08 |
2023-08-12 |
Not clear |
| A Zapata, J L Capdevila, R Trulla. Region-specific and calcium-dependent increase in dialysate choline levels by NMDA. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 10. 1998-06-01. PMID:9570791. |
nmda increased extracellular choline levels four- to fivefold in prefrontal cortex and hippocampus, produced a slight increase in neostriatum, and did not modify dialysate choline in cerebellum. |
1998-06-01 |
2023-08-12 |
Not clear |
| G K Pyapali, D A Turner, C L Williams, W H Meck, H S Swartzwelde. Prenatal dietary choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats. Journal of neurophysiology. vol 79. issue 4. 1998-05-27. PMID:9535948. |
we hypothesized that prenatal (e12-e17) choline supplementation in the rat would lead to an enhancement of hippocampal synaptic plasticity as assessed by long-term potentiation (ltp) at 3-4 mo of age. |
1998-05-27 |
2023-08-12 |
rat |
| S Kar, A M Issa, D Seto, D S Auld, B Collier, R Quirio. Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. Journal of neurochemistry. vol 70. issue 5. 1998-05-18. PMID:9572306. |
amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. |
1998-05-18 |
2023-08-12 |
rat |
| S Kar, A M Issa, D Seto, D S Auld, B Collier, R Quirio. Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. Journal of neurochemistry. vol 70. issue 5. 1998-05-18. PMID:9572306. |
in the present study, we have further characterized a beta-mediated inhibition of ach release and also measured the effects of these peptides on choline acetyltransferase (chat) activity and high-affinity choline uptake (hacu) in hippocampal, cortical, and striatal regions of the rat brain. |
1998-05-18 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, W S Cortes, A Maelicke, E X Albuquerqu. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517478. |
in the present study, we demonstrate that choline, a precursor of acetylcholine (ach) and a product of acetylcholine hydrolysis by acetylcholinesterase (ache), acts as an efficient and relatively selective agonist of alpha7-containing nicotinic acetylcholine receptors (nachr) in neurons cultured from the rat hippocampus, olfactory bulb and thalamus as well as in pc12 cells. |
1998-04-24 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, W S Cortes, A Maelicke, E X Albuquerqu. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517478. |
in contrast, choline did not activate alpha4beta2 agonist-bearing nachrs on hippocampal neurons, and acted as a partial agonist at alpha3beta4-containing nachrs on pc12 cells. |
1998-04-24 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, W S Cortes, A Maelicke, E X Albuquerqu. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517478. |
exposure of cultured hippocampal neurons for 10 min to choline (10-100 microm) resulted in desensitization of the native alpha7 nachrs. |
1998-04-24 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, W S Cortes, A Maelicke, E X Albuquerqu. Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517478. |
moreover, chronic exposure (10 days) of the cultured hippocampal neurons to a desensitizing concentration of choline (approximately 30 microm) decreased their responsiveness to ach. |
1998-04-24 |
2023-08-12 |
rat |
| J M Cermak, T Holler, D A Jackson, J K Blusztaj. Prenatal availability of choline modifies development of the hippocampal cholinergic system. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 12. issue 3. 1998-03-31. PMID:9506479. |
prenatal availability of choline modifies development of the hippocampal cholinergic system. |
1998-03-31 |
2023-08-12 |
rat |