| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yael Abreu-Villaça, Frederic J Seidler, Dan Qiao, Charlotte A Tate, Mandy M Cousins, Indira Thillai, Theodore A Slotki. Short-term adolescent nicotine exposure has immediate and persistent effects on cholinergic systems: critical periods, patterns of exposure, dose thresholds. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 11. 2004-01-28. PMID:12784097. |
in the cerebral cortex, midbrain, and hippocampus, we assessed nicotinic cholinergic receptor (nachr) binding, choline acetyltransferase (chat) activity, a constitutive marker for cholinergic nerve terminals, and [(3)h]hemicholinium-3 (hc-3) binding to the high-affinity choline transporter, which responds to cholinergic synaptic stimulation. |
2004-01-28 |
2023-08-12 |
rat |
| Ivan Tkác, Raghavendra Rao, Michael K Georgieff, Rolf Gruette. Developmental and regional changes in the neurochemical profile of the rat brain determined by in vivo 1H NMR spectroscopy. Magnetic resonance in medicine. vol 50. issue 1. 2003-11-20. PMID:12815675. |
the most sensitive markers for developmental and regional variations between hippocampus, striatum, and cerebral cortex were n-acetylaspartate, myo-inositol, taurine, glutamate, and choline compounds. |
2003-11-20 |
2023-08-12 |
rat |
| J Klein, O Weichel, M Hilgert, J Rupp, S S Chatterjee, H Nawrat. Excitotoxic hippocampal membrane breakdown and its inhibition by bilobalide: role of chloride fluxes. Pharmacopsychiatry. vol 36 Suppl 1. 2003-10-15. PMID:13130393. |
in our experiments, substitution of chloride in the superfusion medium fully blocked the effect of nmda on choline release from hippocampal slices, while the presence of chloride transport inhibitors (furosemide, dids) was partially antagonistic. |
2003-10-15 |
2023-08-12 |
rat |
| Michael J Valenzuela, Megan Jones, Wei Wen, Caroline Rae, Scott Graham, Ronald Shnier, Perminder Sachde. Memory training alters hippocampal neurochemistry in healthy elderly. Neuroreport. vol 14. issue 10. 2003-09-26. PMID:12876468. |
recall of a test-word list of > 23 items was achieved accompanied by elevation of creatine and choline signals in the hippocampus. |
2003-09-26 |
2023-08-12 |
Not clear |
| Thomas Obergriesser, Gabriele Ende, Dieter F Braus, Fritz A Hen. Long-term follow-up of magnetic resonance-detectable choline signal changes in the hippocampus of patients treated with electroconvulsive therapy. The Journal of clinical psychiatry. vol 64. issue 7. 2003-09-23. PMID:12934977. |
long-term follow-up of magnetic resonance-detectable choline signal changes in the hippocampus of patients treated with electroconvulsive therapy. |
2003-09-23 |
2023-08-12 |
Not clear |
| A K Agrawal, Adip Roy, K Seth, Ram Raghubir, P K Set. Restorative potential of cholinergic rich transplants in cholchicine induced lesioned rats: a comparative study of single and multiple micro-transplantation approach. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 21. issue 4. 2003-08-14. PMID:12781786. |
animals were studied for neuro behavioural and neurochemical recovery at 4 and 24 weeks post-transplantation and electrophysiological (single cell recording) and immunohistochemical parameters, choline acetyl transferase (chat) expression was studied in hippocampus at 24 weeks post-transplantation. |
2003-08-14 |
2023-08-12 |
rat |
| A Birthelmer, J Stemmelin, R Jackisch, J-C Casse. Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments. Brain research bulletin. vol 60. issue 3. 2003-08-08. PMID:12754090. |
electrically evoked overflow of tritium was assessed in hippocampal slices preloaded with [3h]choline or [3h]serotonin (5-ht). |
2003-08-08 |
2023-08-12 |
rat |
| Alexander Sartorius, Claudia Neumann-Haefelin, Barbara Vollmayr, Mathias Hoehn, Fritz A Hen. Choline rise in the rat hippocampus induced by electroconvulsive shock treatment. Biological psychiatry. vol 53. issue 7. 2003-07-11. PMID:12679241. |
choline rise in the rat hippocampus induced by electroconvulsive shock treatment. |
2003-07-11 |
2023-08-12 |
human |
| Alexander Sartorius, Claudia Neumann-Haefelin, Barbara Vollmayr, Mathias Hoehn, Fritz A Hen. Choline rise in the rat hippocampus induced by electroconvulsive shock treatment. Biological psychiatry. vol 53. issue 7. 2003-07-11. PMID:12679241. |
human hippocampal choline decreases in major depression episodes. |
2003-07-11 |
2023-08-12 |
human |
| Alexander Sartorius, Claudia Neumann-Haefelin, Barbara Vollmayr, Mathias Hoehn, Fritz A Hen. Choline rise in the rat hippocampus induced by electroconvulsive shock treatment. Biological psychiatry. vol 53. issue 7. 2003-07-11. PMID:12679241. |
we hypothesized a hippocampal choline increase in the rat brain under electroconvulsive shock (ecs) treatment. |
2003-07-11 |
2023-08-12 |
human |
| Zdena Kristofiková, Veronika Platilová, Jan Klaschk. Age- and sex-dependent effects of ethanol on hippocampal hemicholinium-3 sensitive choline carriers during postnatal development of rats. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675122. |
age- and sex-dependent effects of ethanol on hippocampal hemicholinium-3 sensitive choline carriers during postnatal development of rats. |
2003-06-18 |
2023-08-12 |
rat |
| Zdena Kristofiková, Veronika Platilová, Jan Klaschk. Age- and sex-dependent effects of ethanol on hippocampal hemicholinium-3 sensitive choline carriers during postnatal development of rats. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675122. |
our results suggest the noncompetitive binding of alcohol to choline carriers from immature male tissue and correspond with data reporting significant sexual dimorphism of postnatal hippocampal neurons. |
2003-06-18 |
2023-08-12 |
rat |
| Craig D Albright, Donald F Siwek, Corneliu N Craciunescu, Mei-Heng Mar, Neil W Kowall, Christina L Williams, Steven H Zeise. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutritional neuroscience. vol 6. issue 2. 2003-05-16. PMID:12722989. |
choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. |
2003-05-16 |
2023-08-12 |
mouse |
| Craig D Albright, Donald F Siwek, Corneliu N Craciunescu, Mei-Heng Mar, Neil W Kowall, Christina L Williams, Steven H Zeise. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutritional neuroscience. vol 6. issue 2. 2003-05-16. PMID:12722989. |
importantly, decreased calretinin protein was still detectable in hippocampus in aged, 24-month-old mice, born of choline supplemented-dams and maintained since birth on a control diet. |
2003-05-16 |
2023-08-12 |
mouse |
| Craig D Albright, Donald F Siwek, Corneliu N Craciunescu, Mei-Heng Mar, Neil W Kowall, Christina L Williams, Steven H Zeise. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutritional neuroscience. vol 6. issue 2. 2003-05-16. PMID:12722989. |
thus, alterations in the level of calretinin protein in fetal brain hippocampus could underlie the known, life long effects of maternal dietary choline availability on brain development and behavior. |
2003-05-16 |
2023-08-12 |
mouse |
| Anja Birthelmer, Theresa Schweizer, Hélène Jeltsch, Rolf Jackisch, Jean-Christophe Casse. 5,7-Dihydroxytryptamine lesions enhance and serotonergic grafts normalize the evoked overflow of acetylcholine in rat hippocampal slices. The European journal of neuroscience. vol 16. issue 10. 2003-03-05. PMID:12453047. |
about 11 months later, we assessed baseline and electrically evoked release of tritium ([3h]) in hippocampal slices, preloaded with tritiated ([3h])choline or [3h]serotonin (5-ht), in the presence or absence of the 5-ht1b receptor agonist cp-93,129 and the 5-ht receptor antagonist methiothepine. |
2003-03-05 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
in the present study, we have characterized the possible involvement of gaba in igf-i-mediated inhibition of ach release and measured the effects of this growth factor on choline acetyltransferase (chat) activity and high-affinity choline uptake in the hippocampus of the adult rat brain. |
2003-01-23 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
additionally, in contrast to ach release, igf-i did not alter either the activity of the enzyme chat or the uptake of choline in the hippocampus. |
2003-01-23 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
these results, taken together, indicate that igf-i, under acute conditions, can decrease hippocampal ach release by acting on the typical igf-i/irs receptor complex while having no direct effect on chat activity or the uptake of choline. |
2003-01-23 |
2023-08-12 |
rat |
| Jenny Apelt, Ashok Kumar, Reinhard Schlieb. Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human beta-amyloid precursor protein. Brain research. vol 953. issue 1-2. 2003-01-10. PMID:12384234. |
however, high-affinity choline uptake was reduced in the hippocampus of 21-month-old transgenic mice. |
2003-01-10 |
2023-08-12 |
mouse |