| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patrick J Mulholland, Rachel L Self, Barton R Harris, John M Littleton, Mark A Prendergas. Choline exposure reduces potentiation of N-methyl-D-aspartate toxicity by corticosterone in the developing hippocampus. Brain research. Developmental brain research. vol 153. issue 2. 2005-01-13. PMID:15527888. |
choline exposure reduces potentiation of n-methyl-d-aspartate toxicity by corticosterone in the developing hippocampus. |
2005-01-13 |
2023-08-12 |
rat |
| Patrick J Mulholland, Rachel L Self, Barton R Harris, John M Littleton, Mark A Prendergas. Choline exposure reduces potentiation of N-methyl-D-aspartate toxicity by corticosterone in the developing hippocampus. Brain research. Developmental brain research. vol 153. issue 2. 2005-01-13. PMID:15527888. |
organotypic hippocampal slice cultures derived from neonatal rat were pre-treated for 72 h with corticosterone (100 nm) alone or with choline (0.1-10 mm), prior to a brief (1 h) nmda exposure (5 microm). |
2005-01-13 |
2023-08-12 |
rat |
| Eugene P Brandon, Tiffany Mellott, Donald P Pizzo, Nicole Coufal, Kevin A D'Amour, Kevin Gobeske, Mark Lortie, Ignacio López-Coviella, Brygida Berse, Leon J Thal, Fred H Gage, Jan Krzysztof Blusztaj. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 24. 2004-12-20. PMID:15201317. |
however, the amount of choline taken up by cht1 and ach synthesized de novo from choline transported by cht1 in hippocampal slices, as well as levels of cht1 mrna in the septum and cht1 protein in several regions of the cns, were 50-100% higher in chat+/- than in chat+/+ mice. |
2004-12-20 |
2023-08-12 |
mouse |
| C Ayala-Grosso, J Tam, S Xanthoudakis, Y Bureau, S Roy, D W Nicholson, G S Robertso. Effects of fimbria-fornix transection on calpain and choline acetyl transferase activities in the septohippocampal pathway. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207327. |
radioenzymatically determined choline acetyl transferase (chat) activity was elevated in the septum at day 5, but reduced in the dorsal hippocampus at days 3, 5 and 7, after axotomy. |
2004-10-08 |
2023-08-12 |
rat |
| Corneliu N Craciunescu, Craig D Albright, Mei-Heng Mar, Jiannan Song, Steven H Zeise. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. The Journal of nutrition. vol 133. issue 11. 2004-08-24. PMID:14608083. |
choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. |
2004-08-24 |
2023-08-12 |
mouse |
| Corneliu N Craciunescu, Craig D Albright, Mei-Heng Mar, Jiannan Song, Steven H Zeise. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. The Journal of nutrition. vol 133. issue 11. 2004-08-24. PMID:14608083. |
previously, we reported that dietary choline influences development of the hippocampus in fetal rat brain. |
2004-08-24 |
2023-08-12 |
mouse |
| Ori Vatury, Jacob Barg, Theodore A Slotkin, Joseph Yana. Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure. Brain research bulletin. vol 63. issue 1. 2004-07-06. PMID:15121236. |
altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure. |
2004-07-06 |
2023-08-12 |
mouse |
| Zdena Kristofiková, Frantisek Stástný, Vera Bubeniková, Rastislav Druga, Jan Klaschka, Filip Spanie. Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders. Neurochemical research. vol 29. issue 4. 2004-06-03. PMID:15098928. |
our experiments indicate for the first time functional lateralization of the high-affinity choline uptake (hacu) system directly associated with a synthesis of acetylcholine in the hippocampus of wistar rats. |
2004-06-03 |
2023-08-12 |
human |
| Zdena Kristofiková, Frantisek Stástný, Vera Bubeniková, Rastislav Druga, Jan Klaschka, Filip Spanie. Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders. Neurochemical research. vol 29. issue 4. 2004-06-03. PMID:15098928. |
in summary, our results indicate a symmetrical drop in the number of choline carriers of lesioned male rats but a asymmetrical decrease in the activity of remaing carriers, suggesting defects in processes of sexual brain differentiation, leading under normal conditions to the higher activity of carriers in the left hippocampus. |
2004-06-03 |
2023-08-12 |
human |
| Tiffany J Mellott, Christina L Williams, Warren H Meck, Jan Krzysztof Blusztaj. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715695. |
prenatal choline supplementation advances hippocampal development and enhances mapk and creb activation. |
2004-06-01 |
2023-08-12 |
rat |
| Tiffany J Mellott, Christina L Williams, Warren H Meck, Jan Krzysztof Blusztaj. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715695. |
here we show that prenatal choline supplementation causes a 3-day advancement in the ability of juvenile rats to use relational cues in a water maze task, indicating that the treatment accelerates hippocampal maturation. |
2004-06-01 |
2023-08-12 |
rat |
| Tiffany J Mellott, Christina L Williams, Warren H Meck, Jan Krzysztof Blusztaj. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715695. |
moreover, phosphorylation and therefore activation of hippocampal mitogen-activated protein kinase (mapk) and camp-response element binding protein (creb) in response to stimulation by glutamate, n-methyl-d-aspartate, or depolarizing concentrations of k+ were increased by prenatal choline supplementation and reduced by prenatal choline deficiency. |
2004-06-01 |
2023-08-12 |
rat |
| Tiffany J Mellott, Christina L Williams, Warren H Meck, Jan Krzysztof Blusztaj. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715695. |
these data provide the first evidence that developmental plasticity of the hippocampal mapk and creb signaling pathways is controlled by the supply of a single essential nutrient, choline, during fetal development and point to these pathways as candidate mechanisms for the developmental and long-term cognitive enhancement induced by prenatal choline supplementation. |
2004-06-01 |
2023-08-12 |
rat |
| Sabrina Cavallini, Silvia Marino, Lorenzo Beani, Clementina Bianchi, Anna Siniscalch. Nociceptin inhibition of acetylcholine efflux from different brain areas. Neuroreport. vol 14. issue 17. 2004-05-25. PMID:14625441. |
the effects of nociceptin on [3h]choline [3h](ch) efflux from electrically-stimulated rat cortical, hippocampal and caudatal slices as well as from kcl-depolarized synaptosomes and tetrodotoxin-pretreated slices have been studied. |
2004-05-25 |
2023-08-12 |
rat |
| Qiang Li, Shirley Guo-Ross, Darrell V Lewis, Dennis Turner, Aaron M White, Wilkie A Wilson, H Scott Swartzwelde. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. Journal of neurophysiology. vol 91. issue 4. 2004-05-17. PMID:14645379. |
dietary prenatal choline supplementation alters postnatal hippocampal structure and function. |
2004-05-17 |
2023-08-12 |
rat |
| Qiang Li, Shirley Guo-Ross, Darrell V Lewis, Dennis Turner, Aaron M White, Wilkie A Wilson, H Scott Swartzwelde. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. Journal of neurophysiology. vol 91. issue 4. 2004-05-17. PMID:14645379. |
specifically, prenatal choline supplementation has been shown to enhance working memory and hippocampal long-term potentiation (ltp) in adult offspring. |
2004-05-17 |
2023-08-12 |
rat |
| E Düzel, J Kaufmann, S Guderian, A Szentkuti, B Schott, N Bodammer, M Hopf, M Kanowski, C Tempelmann, H J Heinz. Measures of hippocampal volumes, diffusion and 1H MRS metabolic abnormalities in temporal lobe epilepsy provide partially complementary information. European journal of neurology. vol 11. issue 3. 2004-04-27. PMID:15009165. |
volumes, apparent diffusion coefficients (adc) and ratios of n-acetyl-aspartate (naa) to creatine/phosphocreatine (cr) and choline (cho) were measured from each hippocampus during one magnetic resonance imaging (mri) session in patients with tle. |
2004-04-27 |
2023-08-12 |
Not clear |
| Corneliu N Craciunescu, Elliott C Brown, Mei-Heng Mar, Craig D Albright, Marie R Nadeau, Steven H Zeise. Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. The Journal of nutrition. vol 134. issue 1. 2004-02-20. PMID:14704311. |
in mice and rats, maternal dietary choline intake during late pregnancy modulates mitosis and apoptosis in progenitor cells of the fetal hippocampus and septum. |
2004-02-20 |
2023-08-12 |
mouse |
| Jack Knight-Scott, Andreana P Haley, Sarah R Rossmiller, Elana Farace, Vu M Mai, John M Christopher, Carol A Manning, Virginia I Simnad, Helmy M Sirag. Molality as a unit of measure for expressing 1H MRS brain metabolite concentrations in vivo. Magnetic resonance imaging. vol 21. issue 7. 2004-02-19. PMID:14559344. |
using internal water referencing, a two-compartment water model, a simulated brain spectrum for peak identification, and a spectroscopic bi-exponential spin-spin relaxation segmentation technique, we measured the absolute concentrations for the four common 1h brain metabolites: choline (cho), myo-inositol (mino), phosphocreatine + creatine (cr), and n-acetyl-aspartate (naa), in the hippocampal region (n = 26) and along the sylvian fissure (n = 61) of 35 healthy adults. |
2004-02-19 |
2023-08-12 |
Not clear |
| Theresa Schweizer, Anja Birthelmer, Anelise Lazaris, Jean-Christophe Cassel, Rolf Jackisc. 3,4-DAP-evoked transmitter release in hippocampal slices of aged rats with impaired memory. Brain research bulletin. vol 62. issue 2. 2004-02-06. PMID:14638386. |
the experiment compared the accumulation and 3,4-dap-evoked (or nicotine-evoked) overflow of [3h] in hippocampal slices preincubated with [3h]choline, [3h]noradrenaline, or [3h]serotonin. |
2004-02-06 |
2023-08-12 |
rat |