| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven H Zeise. The supply of choline is important for fetal progenitor cells. Seminars in cell & developmental biology. vol 22. issue 6. 2012-02-09. PMID:21693194. |
it is likely that these mechanisms explain why, in rodent models, maternal dietary intake of choline influences both angiogenesis and neurogenesis in fetal hippocampus, and results in life-long changes in memory function. |
2012-02-09 |
2023-08-12 |
Not clear |
| Steven H Zeise. What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. Molecular neurobiology. vol 44. issue 2. 2012-01-23. PMID:21259123. |
maternal diets low in choline alter development of the mouse hippocampus, and decrement memory for life. |
2012-01-23 |
2023-08-12 |
mouse |
| Idun Uhl, Paraskevi Mavrogiorgou, Christine Norra, Frank Forstreuter, Michael Scheel, Henning Witthaus, Seza Ozgürdal, Yehonala Gudlowski, Georg Bohner, Jürgen Gallinat, Randolf Klingebiel, Andreas Heinz, Georg Jucke. 1 H-MR spectroscopy in ultra-high risk and first episode stages of schizophrenia. Journal of psychiatric research. vol 45. issue 9. 2011-12-23. PMID:21397254. |
n-acetylaspartate, choline and creatine were measured in hippocampus, anterior cingulate gyrus (acc) and medial prefrontal cortex (mpfc) of 24 first episode and 30 ultra-high risk patients. |
2011-12-23 |
2023-08-12 |
Not clear |
| André Luis Nunes-Freitas, Anderson Ribeiro-Carvalho, Carla Soares Lima, Ana Carolina Dutra-Tavares, Alex C Manhães, Patricia C Lisboa, Elaine Oliveira, Egberto Gaspar de Moura, Cláudio C Filgueiras, Yael Abreu-Villaç. Nicotine exposure during the third trimester equivalent of human gestation: time course of effects on the central cholinergic system of rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 123. issue 1. 2011-12-20. PMID:21633116. |
in the cerebral cortex, midbrain, and hippocampus, we assessed nicotinic acetylcholine receptor (nachr) binding, [(3)h]hemicholinium-3 (hc-3) binding to the high-affinity choline transporter, choline acetyltransferase (chat), and acetylcholinesterase (ache) activities. |
2011-12-20 |
2023-08-12 |
human |
| John G Mielke, Tarun K Ahuja, Tanya Comas, Geoffrey A R Mealin. Choline-mediated depression of hippocampal synaptic transmission. Nutritional neuroscience. vol 14. issue 5. 2011-12-20. PMID:22005282. |
however, little is known about how choline affects neuronal activity at the population level; therefore, we used extracellular recordings to assess its influence upon synaptic transmission in acutely prepared hippocampal slices. |
2011-12-20 |
2023-08-12 |
Not clear |
| John G Mielke, Tarun K Ahuja, Tanya Comas, Geoffrey A R Mealin. Choline-mediated depression of hippocampal synaptic transmission. Nutritional neuroscience. vol 14. issue 5. 2011-12-20. PMID:22005282. |
our study provides evidence that choline can depress population-level activity, quite likely by facilitating the release of gaba from interneurons, and may thereby influence hippocampal function. |
2011-12-20 |
2023-08-12 |
Not clear |
| Christy M Kelley, Sylvia E Perez, Cassia R Overk, David Wynick, Elliott J Mufso. Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice. Journal of Alzheimer's disease : JAD. vol 25. issue 3. 2011-11-15. PMID:21471639. |
neocortical and hippocampal tissue harvested from 3- and 12-month-old amyloid-β protein precursor (aβpp)swe/ps1Δe9 transgenic (tg) mice were dual-immunolabeled with antibodies against either choline acetyltransferace and aβ (10d5) or galanin (gal) and aβ. |
2011-11-15 |
2023-08-12 |
mouse |
| Laura Ricceri, Bianca De Filippis, Andrea Fuso, Giovanni Laviol. Cholinergic hypofunction in MeCP2-308 mice: beneficial neurobehavioural effects of neonatal choline supplementation. Behavioural brain research. vol 221. issue 2. 2011-09-09. PMID:21457731. |
choline supplementation increased striatal chat activity and also enhanced ngf and bdnf expression in cortical and hippocampal regions. |
2011-09-09 |
2023-08-12 |
mouse |
| Pravinkumar Bhutada, Yogita Mundhada, Kuldeep Bansod, Santosh Tawari, Shaktipal Patil, Pankaj Dixit, Sudhir Umathe, Dharmendra Mundhad. Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21262264. |
lipid peroxidation and glutathione levels as parameters of oxidative stress and choline esterase (che) activity as marker of cholinergic function were assessed in the cerebral cortex and hippocampus. |
2011-07-15 |
2023-08-12 |
rat |
| M M Boccia, M G Blake, M C Krawczyk, C M Baratt. Hippocampal α7 nicotinic receptors modulate memory reconsolidation of an inhibitory avoidance task in mice. Neuroscience. vol 171. issue 2. 2011-02-17. PMID:20832455. |
immediately after the retention test, mice were given intra-dorsal hippocampus infusions of either choline (ch, an α7 nicotinic acetylcholine receptor (α7nachr) agonist, 0.08-1.30 μg/hippocampus), or methyllycaconitine (mla, an α7nachr antagonist, 1.0-30.0 μg/hippocampus). |
2011-02-17 |
2023-08-12 |
mouse |
| Natalia A Crivello, Jan K Blusztajn, James A Joseph, Barbara Shukitt-Hale, Donald E Smit. Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition research (New York, N.Y.). vol 30. issue 10. 2011-02-09. PMID:21056288. |
in adult rats, fd consumption markedly decreased choline levels in the liver, kidneys, and heart; furthermore, choline levels in the cortex and striatum were moderately elevated, although hippocampal choline levels were not affected. |
2011-02-09 |
2023-08-12 |
rat |
| Reza M Salek, Jing Xia, Amy Innes, Brian C Sweatman, Robert Adalbert, Suzanne Randle, Eileen McGowan, Piers C Emson, Julian L Griffi. A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease. Neurochemistry international. vol 56. issue 8. 2010-11-29. PMID:20398713. |
the analysis of the corresponding loading plots for these brain regions indicated a decrease in n-acetyl-l-aspartate, glutamate, glutamine, taurine (exception hippocampus), gamma-amino butyric acid, choline and phosphocholine (combined resonances), creatine, phosphocreatine and succinate in hippocampus, cortex, frontal cortex (exception gamma-amino butyric acid) and midbrain of affected animals. |
2010-11-29 |
2023-08-12 |
mouse |
| Bombi Lee, Bong-Jun Sur, Jeong-Jun Han, Insop Shim, Song Her, Hye-Jung Lee, Dae-Hyun Hah. Krill phosphatidylserine improves learning and memory in Morris water maze in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 6. 2010-11-02. PMID:20677367. |
consistent with the behavioral results, kr-ps treatments significantly alleviated age-associated losses of cholinergic immunoreactivity, and muscarinic acetylcholine receptor type 1 (machr-m1) and choline transporter (cht) mrna expression in the hippocampus. |
2010-11-02 |
2023-08-12 |
rat |
| Can-Jun Ruan, Zhan Li, Li Zhang, Di-Hua Chen, Guan-Hua Du, Lan Su. Protective effects of trans-2, 4-dimethoxystibene on cognitive, impairments induced by Abeta(25-35) in, hypercholesterolemic rats. Brain research bulletin. vol 82. issue 5-6. 2010-11-01. PMID:20451590. |
to further explore the mechanism of s3, the activities of superoxide dismutase (sod), glutathione peroxidase (gsh-px), choline acetyl transferase (chat), acetylcholine esterase (ache) and the contents of malondialdehyde (mda) in hippocampus were analyzed by spectrophotometric method. |
2010-11-01 |
2023-08-12 |
rat |
| Yael Abreu-Villaça, Cláudio Carneiro Filgueiras, Monique Guthierrez, Ana Heloisa de Medeiros, Maria Angélica Mattos, Maurício Dos Santos Pereira, Alex Christian Manhães, Regina Célia Cussa Kubrusl. Exposure to tobacco smoke containing either high or low levels of nicotine during adolescence: differential effects on choline uptake in the cerebral cortex and hippocampus. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 12. issue 7. 2010-10-18. PMID:20457645. |
exposure to tobacco smoke containing either high or low levels of nicotine during adolescence: differential effects on choline uptake in the cerebral cortex and hippocampus. |
2010-10-18 |
2023-08-12 |
Not clear |
| Can-Jun Ruan, Li Zhang, Di-Hua Chen, Zhan Li, Guan-Hua Du, Lan Su. Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Abeta(25-35) both in vitro and in vivo. Neuroscience research. vol 67. issue 3. 2010-09-13. PMID:20346380. |
at the same time, the decreased superoxide dismutase (sod) and choline acetyl transferase (chat) were markedly increased, and the increased acetylcholine esterase (ache) activity was significantly decreased in hippocampus and cortex. |
2010-09-13 |
2023-08-12 |
mouse |
| Mihai G Mehedint, Corneliu N Craciunescu, Steven H Zeise. Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 29. 2010-09-01. PMID:20624989. |
maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. |
2010-09-01 |
2023-08-12 |
mouse |
| Mihai G Mehedint, Corneliu N Craciunescu, Steven H Zeise. Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 29. 2010-09-01. PMID:20624989. |
we conclude that maternal dietary choline intake alters angiogenesis in the developing fetal hippocampus. |
2010-09-01 |
2023-08-12 |
mouse |
| Stacey Carmody, Lorraine Brenna. Effects of pentylenetetrazole-induced seizures on metabolomic profiles of rat brain. Neurochemistry international. vol 56. issue 2. 2010-07-08. PMID:19913064. |
in the hippocampus of ptz-kindled animals the metabolites changing included lactate, succinate, gaba, naa, choline and taurine. |
2010-07-08 |
2023-08-12 |
rat |
| Yanyan Huang, Wenjie Chen, Yuxin Li, Xiaoyan Wu, Xiaomei Shi, Daoying Gen. Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy. Psychiatry research. vol 182. issue 1. 2010-05-27. PMID:20227856. |
effects of antidepressant treatment on n-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)h magnetic resonance spectroscopy. |
2010-05-27 |
2023-08-12 |
human |