| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S B Blunt, P Jenner, C D Marsde. Suppressive effect of L-dopa on dopamine cells remaining in the ventral tegmental area of rats previously exposed to the neurotoxin 6-hydroxydopamine. Movement disorders : official journal of the Movement Disorder Society. vol 8. issue 2. 1993-05-18. PMID:8097279. |
at the end of the treatment period, the number of dopamine cells remaining in each of the lesioned and intact substantia nigra (sn) and vta were assessed, using tyrosine hydroxylase immunohistochemistry. |
1993-05-18 |
2023-08-12 |
rat |
| C A McCormack, B Burnsid. Light and circadian modulation of teleost retinal tyrosine hydroxylase activity. Investigative ophthalmology & visual science. vol 34. issue 5. 1993-05-14. PMID:8097190. |
the authors examined the effects of both light and circadian phase on the synthetic activity of the dopamine producing enzyme, tyrosine hydroxylase (th), in the retina of the midas cichlid (cichlasoma citrinellum). |
1993-05-14 |
2023-08-12 |
Not clear |
| K Kiuchi, K Kiuchi, N Kaneda, T Sasaoka, H Hidaka, T Nagats. Regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying human tyrosine hydroxylase gene. Neuroscience letters. vol 151. issue 1. 1993-05-13. PMID:8097033. |
regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying human tyrosine hydroxylase gene. |
1993-05-13 |
2023-08-12 |
mouse |
| K Kiuchi, K Kiuchi, N Kaneda, T Sasaoka, H Hidaka, T Nagats. Regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying human tyrosine hydroxylase gene. Neuroscience letters. vol 151. issue 1. 1993-05-13. PMID:8097033. |
we investigated the regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying multiple copies of human tyrosine hydroxylase (th). |
1993-05-13 |
2023-08-12 |
mouse |
| P Hantraye, M Varastet, M Peschanski, D Riche, P Cesaro, J C Willer, M Mazier. Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons. Neuroscience. vol 53. issue 1. 1993-05-12. PMID:8469305. |
neuropathological examination of caudate nucleus, putamen, substantia nigra and ventral tegmental area in brain sections stained for tyrosine hydroxylase showed a typical uneven striatal dopamine fibre loss and a neuronal depletion in the dopaminergic mesencephalic cell groups that reproduce those observed in idiopathic parkinson's disease. |
1993-05-12 |
2023-08-12 |
Not clear |
| K Hozawa, T Takasak. Catecholaminergic innervation in the vestibular labyrinth and vestibular nucleus of guinea pigs. Acta oto-laryngologica. Supplementum. vol 503. 1993-05-10. PMID:8097078. |
the vestibular sympathetic fibers of 20 guinea pigs were examined by immunohistochemical demonstration using tyrosine hydroxylase and dopamine b-hydroxylase. |
1993-05-10 |
2023-08-12 |
Not clear |
| S Jiao, V Gurevich, J A Wolf. Long-term correction of rat model of Parkinson's disease by gene therapy. Nature. vol 362. issue 6419. 1993-04-30. PMID:8096625. |
tyrosine hydroxylase converts tyrosine to l-dopa and endogenous decarboxylase activity then converts l-dopa to the neurotransmitter dopamine, which alleviates the symptoms of parkinson's disease. |
1993-04-30 |
2023-08-12 |
rat |
| R J Schuerger, C D Balaba. Immunohistochemical demonstration of regionally selective projections from locus coeruleus to the vestibular nuclei in rats. Experimental brain research. vol 92. issue 3. 1993-04-21. PMID:8095905. |
this study describes a regionally selective projection of tyrosine hydroxylase and dopamine beta-hydroxylase-immunoreactive fibers from locus coeruleus (lc) and the a4 region of nucleus subcoeruleus to the vestibular nuclear complex in long-evans and sprague-dawley rats. |
1993-04-21 |
2023-08-12 |
rat |
| T Bailhache, J Balthazar. The catecholaminergic system of the quail brain: immunocytochemical studies of dopamine beta-hydroxylase and tyrosine hydroxylase. The Journal of comparative neurology. vol 329. issue 2. 1993-04-19. PMID:8095939. |
the catecholaminergic system of the quail brain: immunocytochemical studies of dopamine beta-hydroxylase and tyrosine hydroxylase. |
1993-04-19 |
2023-08-12 |
Not clear |
| T Bailhache, J Balthazar. The catecholaminergic system of the quail brain: immunocytochemical studies of dopamine beta-hydroxylase and tyrosine hydroxylase. The Journal of comparative neurology. vol 329. issue 2. 1993-04-19. PMID:8095939. |
the distribution of dopamine beta-hydroxylase and tyrosine hydroxylase, two key enzymes in the biosynthesis of catecholamines, was investigated by immunocytochemistry in the brain of male and female japanese quail. |
1993-04-19 |
2023-08-12 |
Not clear |
| T Bailhache, J Balthazar. The catecholaminergic system of the quail brain: immunocytochemical studies of dopamine beta-hydroxylase and tyrosine hydroxylase. The Journal of comparative neurology. vol 329. issue 2. 1993-04-19. PMID:8095939. |
cells or fibers showing dopamine beta-hydroxylase and tyrosine hydroxylase immunoreactivity were considered to be noradrenergic or adrenergic, while all structures showing only tyrosine hydroxylase immunoreactivity were tentatively considered to be dopaminergic. |
1993-04-19 |
2023-08-12 |
Not clear |
| B A Bennett, C E Hyde, J R Pecora, J E Clodfelte. Differing neurotoxic potencies of methamphetamine, mazindol, and cocaine in mesencephalic cultures. Journal of neurochemistry. vol 60. issue 4. 1993-04-19. PMID:8095976. |
likewise, treatment of the cultures with mazindol (10(-6) m) resulted in reduced dopamine uptake while not significantly affecting neuron-specific enolase or tyrosine hydroxylase immunostaining. |
1993-04-19 |
2023-08-12 |
Not clear |
| A M Persico, C W Schindler, M T Brannock, A M Gonzalez, C K Surratt, G R Uh. Dopaminergic gene expression during amphetamine withdrawal. Neuroreport. vol 4. issue 1. 1993-04-16. PMID:8095821. |
amphetamine withdrawal could involve the dopaminergic systems that are thought to underlie psychostimulant rewarding effects, and may thus conceivably alter expression of key genes for dopaminergic transmission, including those encoding tyrosine hydroxylase (th), the membrane dopamine transporter (dat) and the synaptic vesicle amine transporter (svat). |
1993-04-16 |
2023-08-12 |
rat |
| E Magal, P Burnham, S Varon, J C Loui. Convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra. Neuroscience. vol 52. issue 4. 1993-04-15. PMID:8095711. |
convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra. |
1993-04-15 |
2023-08-12 |
rat |
| E Magal, P Burnham, S Varon, J C Loui. Convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra. Neuroscience. vol 52. issue 4. 1993-04-15. PMID:8095711. |
ciliary neurotrophic factor and dopamine were found to enhance the expression of tyrosine hydroxylase immunoreactivity in cultured neurons from the substantia nigra of 16-day-old rat fetuses. |
1993-04-15 |
2023-08-12 |
rat |
| E Magal, P Burnham, S Varon, J C Loui. Convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra. Neuroscience. vol 52. issue 4. 1993-04-15. PMID:8095711. |
these results suggest that dopamine and ciliary neurotrophic factor, alone or in combination, are not able to support the survival of tyrosine hydroxylase-positive neurons, but reduce their apparent numerical loss by enhancing the expression of tyrosine hydroxylase. |
1993-04-15 |
2023-08-12 |
rat |
| V M Pickel, J Chan, S R Sesac. Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. Brain research. vol 602. issue 2. 1993-04-13. PMID:8095430. |
we also more directly examined the relationship between dynorphin terminals and dopamine neurons in vta and sn by combining immunoperoxidase labeling of rabbit dynorphin antiserum and immunogold-silver detection of mouse antibodies against tyrosine hydroxylase (th) in single sections through the vta and sn. |
1993-04-13 |
2023-08-12 |
mouse |
| L Iacovitti, M J Evinger, N D Stul. Muscle-derived differentiation factor increases expression of the tyrosine hydroxylase gene and enzyme activity in cultured dopamine neurons from the rat midbrain. Brain research. Molecular brain research. vol 16. issue 3-4. 1993-04-01. PMID:1363326. |
muscle-derived differentiation factor increases expression of the tyrosine hydroxylase gene and enzyme activity in cultured dopamine neurons from the rat midbrain. |
1993-04-01 |
2023-08-11 |
rat |
| C Suri, B P Fung, A S Tischler, D M Chikaraish. Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 3. 1993-03-30. PMID:7680068. |
brain (cath.a) and adrenal (path.1 and path.2) cell lines have been established that synthesize abundant dopamine and norepinephrine and express the appropriate catecholaminergic biosynthetic enzymes, tyrosine hydroxylase (th) and dopamine beta-hydroxylase. |
1993-03-30 |
2023-08-12 |
mouse |
| K T Kim, D H Park, T H Jo. Parallel up-regulation of catecholamine biosynthetic enzymes by dexamethasone in PC12 cells. Journal of neurochemistry. vol 60. issue 3. 1993-03-24. PMID:8436980. |
the levels of mrnas of tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), and dopamine beta-hydroxylase (dbh) were examined at 0, 6, 12, 24, and 48 h after dexamethasone (5 microm) treatment to pc12 cells. |
1993-03-24 |
2023-08-12 |
Not clear |