Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D M Sherry, S Yazull. GABA and glycine in retinal amacrine cells: combined Golgi impregnation and immunocytochemistry. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 342. issue 1302. 1994-03-25. PMID:7509492. |
postembedding immunocytochemistry for tyrosine hydroxylase (the synthetic enzyme for catecholamines) and gaba on serial sections demonstrated colocalization of gaba and a catecholamine, probably dopamine, in a bistratified amacrine cell type. |
1994-03-25 |
2023-08-12 |
Not clear |
S J Augood, K Westmore, P J McKenna, P C Emso. Co-expression of dopamine transporter mRNA and tyrosine hydroxylase mRNA in ventral mesencephalic neurones. Brain research. Molecular brain research. vol 20. issue 4. 1994-03-25. PMID:7906851. |
co-expression of dopamine transporter mrna and tyrosine hydroxylase mrna in ventral mesencephalic neurones. |
1994-03-25 |
2023-08-12 |
rat |
M Navarro, F Rodríguez de Fonseca, M L Hernández, J A Ramos, J J Fernández-Rui. Motor behavior and nigrostriatal dopaminergic activity in adult rats perinatally exposed to cannabinoids. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:7906890. |
in the second experiment, we evaluated neurochemical indices--dopamine (da) and l-3,4-dihydroxyphenylacetic acid (dopac) contents, tyrosine hydroxylase (th) activity, and number and affinity of d1 and d2 dopaminergic receptors in the striatum--and behavioral parameters--spontaneous locomotor activity and spontaneous and induced stereotypic behavior--both indicating nigrostriatal dopaminergic activity, in adult female and male rats perinatally exposed to hashish extract. |
1994-03-25 |
2023-08-12 |
rat |
J R Simon, J A Richter, B Ghett. Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. Journal of neurochemistry. vol 62. issue 2. 1994-03-02. PMID:7905025. |
age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. |
1994-03-02 |
2023-08-12 |
mouse |
J R Simon, J A Richter, B Ghett. Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. Journal of neurochemistry. vol 62. issue 2. 1994-03-02. PMID:7905025. |
dopamine content and tyrosine hydroxylase activity were significantly decreased in the homozygous weaver at all ages studied except postnatal days 7 and 10. |
1994-03-02 |
2023-08-12 |
mouse |
J Zhou, I Date, K Sakai, Y Yoshimoto, T Furuta, S Asari, T Ohmot. Xenogeneic dopaminergic grafts reverse behavioral deficits induced by 6-OHDA in rodents: effect of 15-deoxyspergualin treatment. Neuroscience letters. vol 163. issue 1. 1994-03-02. PMID:8295740. |
the immunohistochemical staining of tyrosine hydroxylase (th) revealed large numbers of surviving dopamine neurons and abundant fibers in the grafted animals. |
1994-03-02 |
2023-08-12 |
mouse |
M Navarro, J J Fernández-Ruiz, R de Miguel, M L Hernández, M Cebeira, J A Ramo. An acute dose of delta 9-tetrahydrocannabinol affects behavioral and neurochemical indices of mesolimbic dopaminergic activity. Behavioural brain research. vol 57. issue 1. 1994-02-25. PMID:8292253. |
neurochemical analyses consisted of measurements of dopamine (da) and l-3,4-dihydroxyphenylacetic acid (dopac) contents, tyrosine hydroxylase activity, in vitro da release and number and affinity of d1 receptors in the limbic forebrain. |
1994-02-25 |
2023-08-12 |
rat |
M G De Montis, C Gambarana, D Melon. Alpha-methyl-para-tyrosine antagonizes the effect of chronic imipramine on learned helplessness in rats. European journal of pharmacology. vol 249. issue 2. 1994-02-24. PMID:7904563. |
alpha-methyl-para-tyrosine, co-administered with imipramine to rats at a dose that only partially inhibits tyrosine hydroxylase, has been found to prevent completely the decrease of dopamine d1 receptor function. |
1994-02-24 |
2023-08-12 |
rat |
C Solà, G Mengod, W C Low, J Norton, B Ghetti, J M Palacios, L C Triarho. Regional distribution of amyloid beta-protein precursor, growth-associated phosphoprotein-43 and microtubule-associated protein 2 messenger RNAs in the nigrostriatal system of normal and Weaver mutant mice and effects of ventral mesencephalic grafts. The European journal of neuroscience. vol 5. issue 11. 1994-02-22. PMID:8287193. |
the survival of dopamine neurons in unilateral intrastriatal grafts was documented by methamphetamine-induced rotational asymmetry tests and by tyrosine hydroxylase immunocytochemistry. |
1994-02-22 |
2023-08-12 |
mouse |
D S Knight, H W Russell, C W Stevens, J A Bea. Transitory noradrenergic and peptidergic nerves in the cat kidney. Journal of the autonomic nervous system. vol 45. issue 2. 1994-02-16. PMID:7904276. |
indirect immunohistochemical methods were used to visualize nerves immunoreactive for tyrosine hydroxylase (th), dopamine beta hydroxylase (dbh), neuropeptide y, (npy) and calcitonin gene-related peptide (cgrp) in sections of the kidneys of cats of different ages. |
1994-02-16 |
2023-08-12 |
cat |
S R Sesack, C Aoki, V M Picke. Ultrastructural localization of D2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:7904306. |
potential cellular substrates for functions ascribed to the dopamine d2 receptor were examined in rat brain using immunoperoxidase for localization of a d2 receptor peptide and immunogold staining for the catecholamine biosynthetic enzyme tyrosine hydroxylase (th). |
1994-02-16 |
2023-08-12 |
rat |
C Hyman, M Juhasz, C Jackson, P Wright, N Y Ip, R M Lindsa. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283241. |
dopaminergic neuron number and phenotypic expression were monitored by tyrosine hydroxylase (th) immunocytochemistry, and measurement of high-affinity dopamine uptake activity and dopamine content, respectively. |
1994-02-16 |
2023-08-12 |
rat |
D Otto, K Unsicke. FGF-2 modulates dopamine and dopamine-related striatal transmitter systems in the intact and MPTP-lesioned mouse. The European journal of neuroscience. vol 5. issue 7. 1994-02-15. PMID:7506615. |
four micrograms fgf-2 soaked into gel foam and placed onto the right striatum partially and bilaterally restored dopamine levels and tyrosine hydroxylase activity after 2 weeks, when the treatment started simultaneously or 1 day after the toxin lesion. |
1994-02-15 |
2023-08-12 |
mouse |
M Zoli, L F Agnati, B Tinner, H W Steinbusch, K Fux. Distribution of dopamine-immunoreactive neurons and their relationships to transmitter and hypothalamic hormone-immunoreactive neuronal systems in the rat mediobasal hypothalamus. A morphometric and microdensitometric analysis. Journal of chemical neuroanatomy. vol 6. issue 5. 1994-02-10. PMID:7506039. |
morphometric and densitometric analysis of dopamine, tyrosine hydroxylase and growth hormone-releasing factor-immunoreactive neurons in the arcuate nucleus showed that dopamine/tyrosine hydroxylase-containing and growth hormone-releasing factor/tyrosine hydroxylase-containing neuronal populations are two largely segregated cell groups with specific localization in the arcuate region, rostrocaudal extension and tyrosine hydroxylase-immunoreactivity content. |
1994-02-10 |
2023-08-12 |
rat |
M Takada, T Kon. 3-Acetylpyridine neurotoxicity to the nigrostriatal dopamine system in mice. Neuroscience letters. vol 161. issue 2. 1994-02-03. PMID:7903802. |
employing tyrosine hydroxylase (th) immunohistochemistry, the neurotoxic effects of 3-acetylpyridine (3-ap), a potent neurotoxin selective to olivocerebellar climbing fibers, on the mesencephalic dopamine systems were investigated in mice. |
1994-02-03 |
2023-08-12 |
mouse |
R G Booth, S D Wyrick, R J Baldessarini, N S Kula, A M Myers, R B Mailma. New sigma-like receptor recognized by novel phenylaminotetralins: ligand binding and functional studies. Molecular pharmacology. vol 44. issue 6. 1994-01-26. PMID:8264560. |
the 6,7-unsubstituted congener (+/-)-(trans)-1-phenyl-3-dimethylamino-1,2,3,4- tetrahydronaphthalene stimulated tyrosine hydroxylase by as much as 50-60% over basal activity, without displacement of dopamine. |
1994-01-26 |
2023-08-12 |
rat |
P Gaspar, A Febvret, J Colomb. Serotonergic sprouting in primate MTP-induced hemiparkinsonism. Experimental brain research. vol 96. issue 1. 1994-01-04. PMID:7902292. |
immunocytochemistry to serotonin, dopamine beta hydroxylase (dbh), and tyrosine hydroxylase (th) was studied in the brains of 2 cebus monkeys that had developed permanent hemiparkinsonism after intracarotid injection of 1.2 mg n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), and were sacrificed after 10-12 months. |
1994-01-04 |
2023-08-12 |
monkey |
S L Vrana, K E Vrana, T R Koves, J E Smith, S I Dworki. Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels. Journal of neurochemistry. vol 61. issue 6. 1993-12-23. PMID:7902421. |
tyrosine hydroxylase (th) and tryptophan hydroxylase (tph) catalyze the rate-limiting steps in dopamine and serotonin biosynthesis, respectively, and are the subject of dynamic regulatory mechanisms that could be sensitive to the actions of cocaine. |
1993-12-23 |
2023-08-12 |
human |
S Kikuchi, H Muramatsu, T Muramatsu, S U Ki. Midkine, a novel neurotrophic factor, promotes survival of mesencephalic neurons in culture. Neuroscience letters. vol 160. issue 1. 1993-12-23. PMID:7902544. |
mk at the optimal concentration of 10 ng/ml promoted the survival of mouse mesencephalic neurons in culture as demonstrated by the increased number of microtubule-associated protein-2 (map2) immunostaining-positive and tyrosine hydroxylase immunostaining-positive neurons and an elevated uptake of radiolabeled dopamine. |
1993-12-23 |
2023-08-12 |
mouse |
A González, R Tuinhof, W J Smeet. Distribution of tyrosine hydroxylase and dopamine immunoreactivities in the brain of the South African clawed frog Xenopus laevis. Anatomy and embryology. vol 187. issue 2. 1993-12-13. PMID:7902028. |
distribution of tyrosine hydroxylase and dopamine immunoreactivities in the brain of the south african clawed frog xenopus laevis. |
1993-12-13 |
2023-08-12 |
xenopus_laevis |