| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K T Delle Donne, P K Sonsall. Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996441. |
meth-induced decrements in neostriatal dopamine content and tyrosine hydroxylase activity in mice were potentiated by concurrent treatment with caffeine, a nonselective adenosine antagonist that blocks both a1 and a2 adenosine receptors. |
1995-01-17 |
2023-08-12 |
mouse |
| A M Myers, P S Charifson, C E Owens, N S Kula, A T McPhail, R J Baldessarini, R G Booth, S D Wyric. Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor. Journal of medicinal chemistry. vol 37. issue 24. 1995-01-09. PMID:7990111. |
molecular modeling studies were carried out on a series of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes (phenylaminotetralins, pats), several pat structural analogs, and various non-pat ligands that demonstrate a range of affinities for a novel sigma 3 receptor linked to stimulation of tyrosine hydroxylase and dopamine synthesis in rodent brain. |
1995-01-09 |
2023-08-12 |
Not clear |
| W Maier, S Schwab, J Hallmayer, M A Ertl, J Minges, M Ackenheil, D Lichtermann, D Wildenaue. Absence of linkage between schizophrenia and the dopamine D4 receptor gene. Psychiatry research. vol 53. issue 1. 1995-01-09. PMID:7991733. |
the dopamine d4 receptor gene and the closely placed tyrosine hydroxylase (th) receptor gene are important candidate genes for schizophrenia; both are located on the short arm of chromosome 11. |
1995-01-09 |
2023-08-12 |
Not clear |
| T Guarnieri, M Virgili, S Carraro, L Villan. Quinolinic acid but not MK-801 protects the dopaminergic system from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced toxicity in goldfish retina. Neurochemistry international. vol 24. issue 6. 1995-01-03. PMID:7981638. |
the toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, intravitreally injected in goldfish eye, involves interplexiform retinal neurons and depletes tyrosine hydroxylase immunoreactivity and dopamine levels. |
1995-01-03 |
2023-08-12 |
Not clear |
| O Hwang, M L Kim, J D Le. Differential induction of gene expression of catecholamine biosynthetic enzymes and preferential increase in norepinephrine by forskolin. Biochemical pharmacology. vol 48. issue 10. 1994-12-30. PMID:7986204. |
we examined the effect of forskolin, an adenylate cyclase activator, on gene expression and the activities of the three enzymes specific for catecholamine biosynthesis [tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh) and phenylethanolamine n-methyltransferase (pnmt)] and on the amounts of available catecholamines in primary cultured bovine adrenomedullary chromaffin cells. |
1994-12-30 |
2023-08-12 |
cattle |
| M J During, J R Naegele, K L O'Malley, A I Gelle. Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science (New York, N.Y.). vol 266. issue 5189. 1994-12-23. PMID:7669103. |
biochemical recovery included increases in both striatal tyrosine hydroxylase enzyme activity and in extracellular dopamine concentrations. |
1994-12-23 |
2023-08-12 |
human |
| K E Vrana, S J Walker, P Rucker, X Li. A carboxyl terminal leucine zipper is required for tyrosine hydroxylase tetramer formation. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964718. |
tyrosine hydroxylase catalyzes the rate-limiting reaction in the biosynthesis of the catecholamine neurotransmitters and hormones (dopamine, norepinephrine, and epinephrine). |
1994-12-23 |
2023-08-12 |
rat |
| I Merchenthale. Induction of enkephalin in tuberoinfundibular dopaminergic neurons of pregnant, pseudopregnant, lactating and aged female rats. Neuroendocrinology. vol 60. issue 2. 1994-12-20. PMID:7969776. |
in cycling female rats these regoins contain only scattered enkephalin-immunoreactive (enk-i) neurons some of which coexpress dopamine, detected by immunostaining for tyrosine hydroxylase (th). |
1994-12-20 |
2023-08-12 |
rat |
| T Hayakawa, K Zy. Fine structure of the supramammillary nucleus of the rat: analysis of the ultrastructural character of dopaminergic neurons. The Journal of comparative neurology. vol 346. issue 1. 1994-12-15. PMID:7962707. |
to determine the morphological features of dopaminergic neurons, we examined the ultrastructural localization of tyrosine hydroxylase (th) immunoreactivity, which is the synthetic enzyme of dopamine, and compared th-immunoreactive neurons to non-th-immunoreactive neurons. |
1994-12-15 |
2023-08-12 |
rat |
| A González, O Marín, R Tuinhof, W J Smeet. Ontogeny of catecholamine systems in the central nervous system of anuran amphibians: an immunohistochemical study with antibodies against tyrosine hydroxylase and dopamine. The Journal of comparative neurology. vol 346. issue 1. 1994-12-15. PMID:7962712. |
ontogeny of catecholamine systems in the central nervous system of anuran amphibians: an immunohistochemical study with antibodies against tyrosine hydroxylase and dopamine. |
1994-12-15 |
2023-08-12 |
xenopus_laevis |
| A González, O Marín, R Tuinhof, W J Smeet. Ontogeny of catecholamine systems in the central nervous system of anuran amphibians: an immunohistochemical study with antibodies against tyrosine hydroxylase and dopamine. The Journal of comparative neurology. vol 346. issue 1. 1994-12-15. PMID:7962712. |
antisera against tyrosine hydroxylase (th) and dopamine (da) revealed that catecholamine systems are already present at early embryonic stages. |
1994-12-15 |
2023-08-12 |
xenopus_laevis |
| M J Lundell, J Hirs. Temporal and spatial development of serotonin and dopamine neurons in the Drosophila CNS. Developmental biology. vol 165. issue 2. 1994-11-29. PMID:7958407. |
we present a high-resolution profile of the temporal and spatial immunoreactivity for dopamine and serotonin in the drosophila embryonic cns and the expression pattern of two enzymes important in their biosynthesis, dopa decarboxylase (ddc) and tyrosine hydroxylase (th). |
1994-11-29 |
2023-08-12 |
drosophila_melanogaster |
| W Maruyama, A Ota, A Takahashi, T Nagatsu, M Nao. Food-derived heterocyclic amines, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole and related amines, as inhibitors of monoamine metabolism. Journal of neural transmission. Supplementum. vol 41. 1994-11-23. PMID:7931246. |
after culture of a dopamine cell model, clonal pheochromocytoma pc12h cells, with trp-p-1 activity of tyrosine hydroxylase was decreased by reduction of its affinity to the biopterin cofactor. |
1994-11-23 |
2023-08-12 |
Not clear |
| A Bonnin, R de Miguel, J J Fernández-Ruiz, M Cebeira, J A Ramo. Possible role of the cytochrome P450-linked monooxygenase system in preventing delta 9-tetrahydrocannabinol-induced stimulation of tuberoinfundibular dopaminergic activity in female rats. Biochemical pharmacology. vol 48. issue 7. 1994-11-23. PMID:7945437. |
it was found that the administration of thc to ovariectomized rats acutely replaced with estradiol (to discard problems derived from differences in the estrogenic status) did not affect either dopamine and l-3,4-dihydroxyphenylacetic acid (dopac) contents and tyrosine hydroxylase activity in the medial basal hypothalamus or the density of d2-dopaminergic receptors in the anterior pituitary. |
1994-11-23 |
2023-08-12 |
rat |
| R Cervini, S Berrard, S Bejanin, J Malle. Regulation by CDF/LIF and retinoic acid of multiple ChAT mRNAs produced from distinct promoters. Neuroreport. vol 5. issue 11. 1994-11-22. PMID:7919195. |
in particular, these molecules alter the activities of the biosynthetic enzymes choline acetyltransferase (chat), tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh). |
1994-11-22 |
2023-08-12 |
rat |
| Y Oomori, H Iuchi, K Ishikawa, Y Satoh, K On. Immunocytochemical study of tyrosine hydroxylase and dopamine beta-hydroxylase immunoreactivities in the rat pancreas. Histochemistry. vol 101. issue 5. 1994-11-21. PMID:7523336. |
immunocytochemical study of tyrosine hydroxylase and dopamine beta-hydroxylase immunoreactivities in the rat pancreas. |
1994-11-21 |
2023-08-12 |
rat |
| Y Oomori, H Iuchi, K Ishikawa, Y Satoh, K On. Immunocytochemical study of tyrosine hydroxylase and dopamine beta-hydroxylase immunoreactivities in the rat pancreas. Histochemistry. vol 101. issue 5. 1994-11-21. PMID:7523336. |
an immunohistochemical and immunoelectron microscopic study was used to demonstrate tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) immunoreactivities in the rat pancreas. |
1994-11-21 |
2023-08-12 |
rat |
| J Mallet, R Meloni, C Lauren. Catecholamine metabolism and psychiatric or behavioral disorders. Current opinion in genetics & development. vol 4. issue 3. 1994-11-18. PMID:7919920. |
other promising results concern the tyrosine hydroxylase gene in manic depressive illness and the dopamine d2 receptor in alcoholism. |
1994-11-18 |
2023-08-12 |
Not clear |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
we examined the synaptic basis for 5-ht modulation of neurons in the ventral tegmental area which either (i) project to the nucleus accumbens or (ii) contain the catecholamine synthesizing enzyme tyrosine hydroxylase, a marker of dopamine neurons in this brain region. |
1994-11-10 |
2023-08-12 |
rat |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
the prominence of asymmetric junctions formed by 5-ht-labeled terminals on neurons projecting to the nucleus accumbens and those containing tyrosine hydroxylase in the ventral tegmental area suggests a cellular basis for serotonergic excitation of mesoaccumbens dopamine neurons. |
1994-11-10 |
2023-08-12 |
rat |