| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C W Kerr, L J Lee, A A Romero, N D Stull, L Iacovitt. Purification of dopamine neurons by flow cytometry. Brain research. vol 665. issue 2. 1995-04-25. PMID:7895066. |
nearly all cells recovered as fluorescent positive (> 98%) were also immunoreactive for the dopamine specific enzyme tyrosine hydroxylase (80%-96%). |
1995-04-25 |
2023-08-12 |
rat |
| H Moukhles, M Amalric, A Nieoullon, A Daszut. Behavioural recovery of rats grafted with dopamine cells after partial striatal dopaminergic depletion in a conditioned reaction-time task. Neuroscience. vol 63. issue 1. 1995-04-25. PMID:7898663. |
these differences in the performance deficits appeared to be in relation to the extent of the dopamine denervation within the striatum assessed by the tyrosine hydroxylase immunostaining. |
1995-04-25 |
2023-08-12 |
rat |
| B J Ciliax, C Heilman, L L Demchyshyn, Z B Pristupa, E Ince, S M Hersch, H B Niznik, A I Leve. The dopamine transporter: immunochemical characterization and localization in brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 1. 1995-04-20. PMID:7534339. |
however, certain mismatches between immunocytochemical distributions of dat and tyrosine hydroxylase were apparent, indicating that dopaminergic systems are heterogeneous and may use independent mechanisms for the regulation of dopamine levels in brain. |
1995-04-20 |
2023-08-12 |
human |
| J R Simon, B Ghett. The weaver mutant mouse as a model of nigrostriatal dysfunction. Molecular neurobiology. vol 9. issue 1-3. 1995-04-18. PMID:7888095. |
striatal tyrosine hydroxylase and dopamine content are reduced by 60-70%, and dopamine uptake is reduced by as much as 95%. |
1995-04-18 |
2023-08-12 |
mouse |
| E H Stotz, J M Palacios, B Landwehrmeyer, J Norton, B Ghetti, J R Simon, L C Triarho. Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse. Journal of neural transmission. General section. vol 97. issue 1. 1995-04-17. PMID:7888149. |
in the striatum of the homozygous weaver mutant mouse (wv/wv), dopamine content, uptake and tyrosine hydroxylase activity are decreased compared to wild-type (+/+) mice. |
1995-04-17 |
2023-08-12 |
mouse |
| X H Zhong, J W Haycock, K Shannak, Y Robitaille, J Fratkin, A H Koeppen, O Hornykiewicz, S J Kis. Striatal dihydroxyphenylalanine decarboxylase and tyrosine hydroxylase protein in idiopathic Parkinson's disease and dominantly inherited olivopontocerebellar atrophy. Movement disorders : official journal of the Movement Disorder Society. vol 10. issue 1. 1995-04-13. PMID:7885342. |
we measured the levels of dopamine, tyrosine hydroxylase (th) protein, and dihydroxyphenylalanine (dopa) decarboxylase (ddc) protein in the striatum of 10 patients with idiopathic parkinson's disease (pd) and 23 patients with dominantly inherited olivopontocerebellar atrophy (opca). |
1995-04-13 |
2023-08-12 |
human |
| T Gasull, M Giralt, A Garcia, J Hidalg. Regulation of metallothionein-I+II levels in specific brain areas and liver in the rat: role of catecholamines. Glia. vol 12. issue 2. 1995-03-27. PMID:7868187. |
the inhibition of tyrosine hydroxylase with alpha-methyl-p-tyrosine (mpt), which depletes brain dopamine, noradrenaline, and adrenaline, increased mt levels in all brain areas studied (frontal cortex, cortex, medulla oblongata plus pons, midbrain, striatum, hippocampus, hypothalamus, and cerebellum) when considering the results of two separate experiments. |
1995-03-27 |
2023-08-12 |
human |
| J Liptrot, D Holdup, O Phillipso. 1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol inhibits tyrosine hydroxylase activity in rat striatal synaptosomes. Journal of neural transmission. General section. vol 96. issue 1. 1995-03-22. PMID:7857591. |
1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (tmiq), a tetrahydroisoquinoline derivative of adrenaline, was tested for potency as an analog of the dopamine depleting agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) in assays of tyrosine hydroxylase (th) activity in the striatal synaptosome preparation. |
1995-03-22 |
2023-08-12 |
rat |
| L Medina, L Puelles, W J Smeet. Development of catecholamine systems in the brain of the lizard Gallotia galloti. The Journal of comparative neurology. vol 350. issue 1. 1995-03-20. PMID:7860800. |
for a better insight into general and derived traits of developmental aspects of catecholaminergic (ca) systems in amniotes, we have studied the development of these systems in the brain of a lizard, gallotia galloti, with tyrosine hydroxylase (th)- and dopamine (da) immunohistochemical techniques. |
1995-03-20 |
2023-08-12 |
Not clear |
| A Smargiassi, C Biagini, A Mutti, E Bergamaschi, A Bacchini, R Alinovi, S Cavazzin. Multiple interferences on catecholamine metabolism by tetrahydroisoquinolines (TIQs). Neurotoxicology. vol 15. issue 3. 1995-03-16. PMID:7854617. |
the activities of tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) were measured by hplc-based methods following exposure to variable concentrations of tiqs. |
1995-03-16 |
2023-08-12 |
human |
| I Irwin, L E DeLanney, T McNeill, P Chan, L S Forno, G M Murphy, D A Di Monte, M S Sandy, J W Langsto. Aging and the nigrostriatal dopamine system: a non-human primate study. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 3. issue 4. 1995-03-09. PMID:7531106. |
finally, because the number of tyrosine hydroxylase (th) positive cells remains constant with age, these results raise the possibility that therapeutic strategies aimed at increasing dopamine concentrations may benefit elderly individuals. |
1995-03-09 |
2023-08-12 |
monkey |
| Y Wakabayashi, Y Makiura, T Tomoyoshi, K Kitahama, M Geffard, T Maed. Adrenergic innervation of the urinary bladder body in the cat with special reference to structure of the detrusor muscle: an immunohistochemical study of noradrenaline and its synthesizing enzymes. Archives of histology and cytology. vol 57. issue 3. 1995-02-16. PMID:7818951. |
the distribution of adrenergic nerves in the body detrusor muscle of the cat urinary bladder was studied by means of the immunohistochemical identification of noradrenaline (na) and the na synthesizing enzymes tyrosine hydroxylase, aromatic l-aminoacid decarboxylase and dopamine beta-hydroxylase. |
1995-02-16 |
2023-08-12 |
cat |
| S F Ali, S N David, G D Newport, J L Cadet, W Slikke. MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels. Synapse (New York, N.Y.). vol 18. issue 1. 1995-02-16. PMID:7825121. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) causes marked depletion of dopamine (da) levels and reduction in the activity of tyrosine hydroxylase (th) in the nigrostriatal da pathway. |
1995-02-16 |
2023-08-12 |
mouse |
| A González, M Muñoz, A Muñoz, O Marin, W J Smeet. On the basal ganglia of amphibians: dopaminergic mesostriatal projections. European journal of morphology. vol 32. issue 2-4. 1995-01-31. PMID:7803178. |
immunohistochemistry with antibodies against tyrosine hydroxylase (th) and dopamine (da) demonstrated some remarkable differences in the distribution of da fibers within the basal forebrain. |
1995-01-31 |
2023-08-12 |
Not clear |
| J K Andersen, D M Frim, O Isacson, M F Beal, X O Breakefiel. Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Brain research. vol 656. issue 1. 1995-01-31. PMID:7804823. |
levels of striatal dopamine (da) and its metabolite 3,4-dihydroxyphenylacetic acid (dopac), as well as tyrosine hydroxylase (th)-immunopositive cell numbers in the substantia nigra (sn) were compared 1 week later between transgenics and controls. |
1995-01-31 |
2023-08-12 |
mouse |
| J Zhou, H F Bradford, G M Ster. The response of human and rat fetal ventral mesencephalon in culture to the brain-derived neurotrophic factor treatment. Brain research. vol 656. issue 1. 1995-01-31. PMID:7804829. |
dopaminergic neuron viability and phenotypic expression were monitored by tyrosine hydroxylase (th) immunohistochemistry and measurement of dopamine (da) content with hplc, respectively. |
1995-01-31 |
2023-08-12 |
human |
| P Onali, E Mosca, M C Oliana. Presynaptic dopamine autoreceptors and second messengers controlling tyrosine hydroxylase activity in rat brain. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365463. |
presynaptic dopamine autoreceptors and second messengers controlling tyrosine hydroxylase activity in rat brain. |
1995-01-30 |
2023-08-11 |
rat |
| P Onali, E Mosca, M C Oliana. Presynaptic dopamine autoreceptors and second messengers controlling tyrosine hydroxylase activity in rat brain. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365463. |
in brain areas enriched of dopaminergic nerve terminals presynaptic dopamine (da) autoreceptors control the state of activation of tyrosine hydroxylase (th) by regulating the extent of phosphorylation of the enzyme. |
1995-01-30 |
2023-08-11 |
rat |
| Y Oomori, K Nakaya, H Tanaka, H Iuchi, K Ishikawa, Y Satoh, K On. Immunohistochemical and histochemical evidence for the presence of noradrenaline, serotonin and gamma-aminobutyric acid in chief cells of the mouse carotid body. Cell and tissue research. vol 278. issue 2. 1995-01-25. PMID:8001081. |
the immunohistochemical study revealed tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt), serotonin, glutamate decarboxylase (gad) and gamma-aminobutyric acid (gaba) immunoreactivities in the mouse carotid body. |
1995-01-25 |
2023-08-12 |
mouse |
| A Chéramy, J M Desce, G Godeheu, J Glowinsk. Presynaptic control of dopamine synthesis and release by excitatory amino acids in rat striatal synaptosomes. Neurochemistry international. vol 25. issue 2. 1995-01-19. PMID:7994195. |
the inhibition of [3h]dopamine synthesis resulting from the stimulation of nmda receptors was prevented when synaptosomes were continuously superfused with adenosine deaminase and quinpirole, a combined treatment known to markedly reduce the phosphorylation of tyrosine hydroxylase by camp-dependent protein kinase. |
1995-01-19 |
2023-08-12 |
rat |