| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kazula, J Z Nowak, P M Iuvon. Regulation of melatonin and dopamine biosynthesis in chick retina: the role of GABA. Visual neuroscience. vol 10. issue 4. 1993-08-30. PMID:8101728. |
the rate of dopamine synthesis, estimated from in situ tyrosine hydroxylase activity, was higher in light-exposed retinas than in darkness. |
1993-08-30 |
2023-08-12 |
chicken |
| K Vrecko, J G Birkmayer, J Krain. Stimulation of dopamine biosynthesis in cultured PC 12 phaeochromocytoma cells by the coenzyme nicotinamide adeninedinucleotide (NADH). Journal of neural transmission. Parkinson's disease and dementia section. vol 5. issue 2. 1993-08-20. PMID:8101444. |
the experiment shows that nadh is able to increase the activity of the tyrosine hydroxylase and dopamine - production in pc 12 cells up to 6 times. |
1993-08-20 |
2023-08-12 |
rat |
| T Nagats. Enzymatic stimulation and enzymatic inhibition in Parkinson's disease. Acta neurologica Scandinavica. Supplementum. vol 146. 1993-08-18. PMID:8101411. |
in order to supplement the deficient catecholamine neurotransmitters, dopamine and noradrenaline, in parkinsonian brains, the following strategies have been tried: (1) the precursor amino acids, l-dopa and l-threo-dihydroxyphenylserine (dops), (2) 6r-l-erythro-tetrahydrobiopterin (bph4) as tyrosine hydroxylase (th) cofactor and nicotinamide adenine dinucleotide (nadh) as cofactor of dihydropteridine reductase to stimulate th, (3) brain transplant of th-containing cells, (4) inhibitors of monoamine oxidase (mao) and/or catechol o-methyltransferase (comt) with or without l-dopa or l-dops, and (5) dopamine receptor agonists. |
1993-08-18 |
2023-08-12 |
Not clear |
| M Navarro, J J Fernández-Ruiz, R De Miguel, M L Hernández, M Cebeira, J A Ramo. Motor disturbances induced by an acute dose of delta 9-tetrahydrocannabinol: possible involvement of nigrostriatal dopaminergic alterations. Pharmacology, biochemistry, and behavior. vol 45. issue 2. 1993-08-11. PMID:8392200. |
neurochemical analyses were measurements of presynaptic activity--dopamine (da) and l-3,4-dihydroxyphenylacetic acid (dopac) contents, tyrosine hydroxylase (th) activity, and in vitro da release--and postsynaptic sensitivity--number and affinity of d1 and d2 receptors--in the striatum. |
1993-08-11 |
2023-08-12 |
rat |
| L C Doerin. Peripheral nerve segments promote consistent long-term survival of adrenal medulla transplants in the brain. Experimental neurology. vol 118. issue 3. 1993-08-06. PMID:1363982. |
the grafts consist of a stable population of approximately 2.0 x 10(3) chromaffin cells that survive for at least 6 months (longest time point studied): immunoreactivity to catecholamine-related enzymes (tyrosine hydroxylase, dopamine beta-hydroxylase) and the low-affinity ngf receptor (192-igg) are expressed by the chromaffin cells. |
1993-08-06 |
2023-08-11 |
Not clear |
| M Sakai, I Nagats. Alteration of carnosine expression in olfactory system of mouse after unilateral naris closure and partial bulbectomy. Journal of neuroscience research. vol 34. issue 6. 1993-07-23. PMID:8100280. |
after unilateral naris closure, carnosine staining showed no alteration, but immunoreactivity of tyrosine hydroxylase (th), the rate-limiting enzyme for biosynthesis of dopamine in dopaminergic neurons, decreased dramatically in periglomerular neurons. |
1993-07-23 |
2023-08-12 |
mouse |
| M Fillenz, S C Stanford, B G Cole. Changes in sympathetic nerve terminals in the heart of cold-exposed rats. Journal of neurochemistry. vol 61. issue 1. 1993-07-22. PMID:8515259. |
as a measure of tyrosine hydroxylase activity, whole ventricular noradrenaline, dopamine, and dihydroxyphenylacetic acid content were used. |
1993-07-22 |
2023-08-12 |
rat |
| E Ottaviani, E Caselgrandi, A Franchini, C Francesch. CRF provokes the release of norepinephrine by hemocytes of Viviparus ater (Gastropoda, Prosobranchia): further evidence in favour of the evolutionary hypothesis of the mobile immune-brain. Biochemical and biophysical research communications. vol 193. issue 1. 1993-07-01. PMID:8503933. |
moreover, immunoreactive tyrosine hydroxylase and dopamine beta-hydroxylase, i.e., the enzymes involved in biogenic amine biosynthesis, have been demonstrated in hemocytes. |
1993-07-01 |
2023-08-12 |
Not clear |
| K Gebreyesus, E J Kilbourne, E L Sabba. Bradykinin elevates tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in PC12 cells. Brain research. vol 608. issue 2. 1993-06-21. PMID:8098650. |
bradykinin elevates tyrosine hydroxylase and dopamine beta-hydroxylase mrna levels in pc12 cells. |
1993-06-21 |
2023-08-12 |
Not clear |
| A Ueki, L Rosén, B Andbjer, U B Finnman, U Altamimi, A M Janson, M Goldstein, L F Agnati, K Fux. The vigilance-promoting drug modafinil counteracts the reduction of tyrosine hydroxylase immunoreactivity and of dopamine stores in nigrostriatal dopamine neurons in the male rat after a partial transection of the dopamine pathway. Experimental brain research. vol 93. issue 2. 1993-06-16. PMID:8098283. |
the vigilance-promoting drug modafinil counteracts the reduction of tyrosine hydroxylase immunoreactivity and of dopamine stores in nigrostriatal dopamine neurons in the male rat after a partial transection of the dopamine pathway. |
1993-06-16 |
2023-08-12 |
rat |
| A Ueki, L Rosén, B Andbjer, U B Finnman, U Altamimi, A M Janson, M Goldstein, L F Agnati, K Fux. The vigilance-promoting drug modafinil counteracts the reduction of tyrosine hydroxylase immunoreactivity and of dopamine stores in nigrostriatal dopamine neurons in the male rat after a partial transection of the dopamine pathway. Experimental brain research. vol 93. issue 2. 1993-06-16. PMID:8098283. |
we studied the ability of the vigilance-promoting drug modafinil to modulate the anterograde and retrograde changes in tyrosine hydroxylase (th) immunoreactivity and in dopamine (da) stores in the nigro-neostriatal da neurons, following a partial hemitransection of this ascending da system, using a combined morphometrical, biochemical and behavioural analysis. |
1993-06-16 |
2023-08-12 |
rat |
| T F Batten, P A Berry, A Maqbool, L Moons, F Vandesand. Immunolocalization of catecholamine enzymes, serotonin, dopamine and L-dopa in the brain of Dicentrarchus labrax (Teleostei). Brain research bulletin. vol 31. issue 3-4. 1993-06-11. PMID:8098256. |
antisera to serotonin (5-ht), dopamine, and l-dopa, and to the catecholamine synthesizing enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyl transferase (pnmt), were used to localize monoamine containing neurones in the brain of dicentrarchus labrax (sea bass). |
1993-06-11 |
2023-08-12 |
Not clear |
| P A Lapchak, K D Beck, D M Araujo, I Irwin, J W Langston, F Heft. Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neuroscience. vol 53. issue 3. 1993-06-08. PMID:8098137. |
the behavioral asymmetry was paralleled by reductions of striatal [3h]dopamine uptake (27%), tyrosine hydroxylase activity (68%), dopamine content (36%) and [3h]mazindol binding site density (35%) on the same side as brain-derived neurotrophic factor treatment. |
1993-06-08 |
2023-08-12 |
human |
| P A Lapchak, K D Beck, D M Araujo, I Irwin, J W Langston, F Heft. Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neuroscience. vol 53. issue 3. 1993-06-08. PMID:8098137. |
the medial forebrain lesions decreased the following markers of striatal dopaminergic function: [3h]opamine uptake (65%), tyrosine hydroxylase activity (79%), dopamine content (80%) and [3h]mazindol binding site density (52%), induced a pronounced loss of tyrosine hydroxylase-positive cell bodies within the substantia nigra and also reduced tyrosine hydroxylase messenger rna levels. |
1993-06-08 |
2023-08-12 |
human |
| A Maqbool, T F Batten, P A Berry, P N McWillia. Distribution of dopamine-containing neurons and fibres in the feline medulla oblongata: a comparative study using catecholamine-synthesizing enzyme and dopamine immunohistochemistry. Neuroscience. vol 53. issue 3. 1993-06-08. PMID:8098139. |
the distribution of dopamine-immunoreactive neurons and fibres in the feline medulla oblongata was examined by immunocytochemistry with antisera to the catecholamine-synthesizing enzymes tyrosine hydroxylase, dopamine-beta-hydroxylase and phenylethanolamine-n-methyltransferase, and with antisera to the catecholamines dopamine and l-dihydroxyphenylalanine. |
1993-06-08 |
2023-08-12 |
Not clear |
| A Maqbool, T F Batten, P A Berry, P N McWillia. Distribution of dopamine-containing neurons and fibres in the feline medulla oblongata: a comparative study using catecholamine-synthesizing enzyme and dopamine immunohistochemistry. Neuroscience. vol 53. issue 3. 1993-06-08. PMID:8098139. |
double-staining studies with antisera to the enzymes indicated that a population of neurons within both regions were immunoreactive for tyrosine hydroxylase but not dopamine-beta-hydroxylase or phenylethanolamine-n-methyltransferase, implying that they synthesize dopamine. |
1993-06-08 |
2023-08-12 |
Not clear |
| C B Watt, V J Florac. A double-label analysis demonstrating the non-coexistence of tyrosine hydroxylase-like and GABA-like immunoreactivities in amacrine cells of the larval tiger salamander retina. Neuroscience letters. vol 148. issue 1-2. 1993-05-26. PMID:1363755. |
previous studies have localized tyrosine hydroxylase, the rate-limiting enzyme for the production of dopamine, and gamma-aminobutyric acid (gaba) to amacrine cell populations in the larval tiger salamander retina. |
1993-05-26 |
2023-08-11 |
Not clear |
| Y Tillet, J Thibaul. Morphological relationships between tyrosine hydroxylase-immunoreactive neurons and dopamine-beta-hydroxylase-immunoreactive fibres in dopamine cell group A15 of the sheep. Journal of chemical neuroanatomy. vol 6. issue 2. 1993-05-26. PMID:8097398. |
double immunocytochemical labelling with antibodies raised against tyrosine hydroxylase (th) and dopamine-beta-hydroxylase was used on semi-thin sections of sheep hypothalamus to investigate possible morphological relationships between dopamine neurons of group a15 and noradrenaline afferents to this area. |
1993-05-26 |
2023-08-12 |
Not clear |
| T Scimonelli, M Marucco, M E Celi. Evidence for catecholaminergic control of alpha-melanotropin (alpha-MSH) content in hypothalamic areas. Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia. vol 42. issue 2. 1993-05-25. PMID:1363745. |
the tyrosine hydroxylase inhibitor alpha-methyl-para-tyrosine (300mg/kg) increased the hypothalamic alpha-msh content in medial basal hypothalamus and preoptic hypothalamic area when it was measured at 22:00 h. diethyldithiocarbamate (600mg/kg), which inhibits dopamine beta-hydroxylase, as well as 2-3-dichloromethylbenzylamide (25mg/kg), which acts on the phenylethanolamine-nch3 transferase also increased the alpha-msh content in the above mentioned discrete areas. |
1993-05-25 |
2023-08-11 |
rat |
| M S Davidoff, W Schulze, R Middendorff, A F Holstei. The Leydig cell of the human testis--a new member of the diffuse neuroendocrine system. Cell and tissue research. vol 271. issue 3. 1993-05-20. PMID:8472301. |
we were able to reveal immunoreactivity for enzymes involved in the synthesis of the catecholamines dopamine and noradrenaline (tyrosine hydroxylase, aromatic l-amino acid decarboxylase, dopamine-beta-hydroxylase), for the indolamine 5-hydroxytryptamine (serotonin), as well as for a number of well-known neuronal markers such as the neurofilament protein 200, synaptophysin, chromogranin a + b, the neural cell-adhesion molecule (n-cam), the microtubule-associated protein (map-2), and the calcium-binding proteins: s-100, calbindin and parvalbumin. |
1993-05-20 |
2023-08-12 |
human |