| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L T Weiss-Wunder, M F Chessele. Acute and repeated administration of fluphenazine-N-mustard alters levels of tyrosine hydroxylase mRNA in subsets of mesencephalic dopaminergic neurons. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359452. |
acute treatment with fluphenazine-n-mustard induced an increase in both striatal dopamine turnover and the level of tyrosine hydroxylase mrna in the substantia nigra but not the ventral tegmental area. |
1992-12-14 |
2023-08-11 |
mouse |
| L T Weiss-Wunder, M F Chessele. Acute and repeated administration of fluphenazine-N-mustard alters levels of tyrosine hydroxylase mRNA in subsets of mesencephalic dopaminergic neurons. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359452. |
after two days of repeated drug injections (twice daily), tyrosine hydroxylase mrna was decreased in the substantia nigra despite the persistence of an elevated dopamine turnover in the striatum. |
1992-12-14 |
2023-08-11 |
mouse |
| L T Weiss-Wunder, M F Chessele. Acute and repeated administration of fluphenazine-N-mustard alters levels of tyrosine hydroxylase mRNA in subsets of mesencephalic dopaminergic neurons. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359452. |
the following decrease in mrna levels precedes desensitization to the effects of the drug on dopamine turnover, further illustrating a lack of correspondence between increased neurotransmission and levels of tyrosine hydroxylase mrna in catecholaminergic neurons of the central nervous system. |
1992-12-14 |
2023-08-11 |
mouse |
| G H Paalzo. L-dopa induces opposing effects on pain in intact rats: (-)-sulpiride, SCH 23390 or alpha-methyl-DL-p-tyrosine methylester hydrochloride reveals profound hyperalgesia in large antinociceptive doses. The Journal of pharmacology and experimental therapeutics. vol 263. issue 2. 1992-12-08. PMID:1432683. |
moreover, profound hyperalgesia is revealed by either dopamine (da) d1 and d2 receptor blockade by means of sch 23390 [r-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetra-hydro-1h- 3-benzazepine hydrochloride] or (-)-sulpiride, respectively, as well as after a reduction of the presynaptic synthesis of catecholamines after pretreatment of the animals with the tyrosine hydroxylase inhibitor alpha-methyl-dl-p-tyrosine (alpha-mpt). |
1992-12-08 |
2023-08-11 |
rat |
| P Ribeiro, Y Wang, B A Citron, S Kaufma. Regulation of recombinant rat tyrosine hydroxylase by dopamine. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 20. 1992-11-17. PMID:1357665. |
regulation of recombinant rat tyrosine hydroxylase by dopamine. |
1992-11-17 |
2023-08-11 |
rat |
| P Ribeiro, Y Wang, B A Citron, S Kaufma. Regulation of recombinant rat tyrosine hydroxylase by dopamine. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 20. 1992-11-17. PMID:1357665. |
labeled dopamine binds to tyrosine hydroxylase with high affinity (kd = 1 microm) but low stoichiometry (r = 0.08 mol/mol of enzyme subunit). |
1992-11-17 |
2023-08-11 |
rat |
| H K Choi, L Won, J D Roback, B H Wainer, A Helle. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 19. 1992-11-10. PMID:1357658. |
when mn9d cells were coaggregated with primary embryonic cells of optic tectum, a brain region that does not receive a dopaminergic innervation, there was a marked reduction in their dopamine content, tyrosine hydroxylase immunoreactivity, and tyrosine hydroxylase mrna. |
1992-11-10 |
2023-08-11 |
Not clear |
| D A Wilson, J G Woo. Functional consequences of unilateral olfactory deprivation: time-course and age sensitivity. Neuroscience. vol 49. issue 1. 1992-11-06. PMID:1357586. |
in addition, an attempt was made to correlate these physiological measures with olfactory bulb dopamine and norepinephrine levels and tyrosine hydroxylase immunoreactivity. |
1992-11-06 |
2023-08-11 |
rat |
| J A Richter, E H Stotz, B Ghetti, J R Simo. Comparison of alterations in tyrosine hydroxylase, dopamine levels, and dopamine uptake in the striatum of the weaver mutant mouse. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1356243. |
comparison of alterations in tyrosine hydroxylase, dopamine levels, and dopamine uptake in the striatum of the weaver mutant mouse. |
1992-10-22 |
2023-08-11 |
mouse |
| G D Crawford, W D Le, R G Smith, W J Xie, E Stefani, S H Appe. A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 9. 1992-10-19. PMID:1356145. |
the cell line contains tyrosine hydroxylase, which is identifiable both by biochemical and immunological methods and synthesizes dopamine, but no other catecholamine. |
1992-10-19 |
2023-08-11 |
rat |
| G D Crawford, W D Le, R G Smith, W J Xie, E Stefani, S H Appe. A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 9. 1992-10-19. PMID:1356145. |
at least three neuronal features, namely, tyrosine hydroxylase, dopamine synthesis, and omega-conotoxin receptor expression, are quantitatively elevated after sustained treatment with camp analogs. |
1992-10-19 |
2023-08-11 |
rat |
| A R Green, R J De Souza, J L Williams, T K Murray, A J Cros. The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole. Neuropharmacology. vol 31. issue 4. 1992-10-09. PMID:1381816. |
this procedure produced a 66% loss of striatal dopamine and a 50% loss of tyrosine hydroxylase activity 3 days later. |
1992-10-09 |
2023-08-11 |
mouse |
| A R Green, R J De Souza, J L Williams, T K Murray, A J Cros. The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole. Neuropharmacology. vol 31. issue 4. 1992-10-09. PMID:1381816. |
), given 15 min before each dose of methamphetamine, totally prevented the methamphetamine-induced loss of tyrosine hydroxylase activity and partly prevented the loss of dopamine. |
1992-10-09 |
2023-08-11 |
mouse |
| S A Berry, G A Gudelsk. Evidence for protein kinase-C mediation of the neurotensin-induced activation of tyrosine hydroxylase in tuberoinfundibular dopaminergic neurons. Endocrinology. vol 131. issue 3. 1992-09-22. PMID:1354601. |
the purpose of the present study was to determine whether neurotensin acts within the arcuate nucleus/median eminence to activate tyrosine hydroxylase (th) within tuberoinfundibular dopamine neurons. |
1992-09-22 |
2023-08-11 |
Not clear |
| D A Ruggiero, M Anwar, P M Gootma. Presumptive adrenergic neurons containing phenylethanolamine N-methyltransferase immunoreactivity in the medulla oblongata of neonatal swine. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1354561. |
pnmt-immunoreactive (ir) neuronal somata, however, were largely confined to the reticular formation in the ventrolateral quadrant and the nucleus tractus solitarii (nts) and more restricted in distribution than those expressing tyrosine hydroxylase (th) and dopamine beta-hydroxylase (d beta h)-ir on serial transverse sections. |
1992-09-18 |
2023-08-11 |
human |
| C F Phelix, Z Liposits, W K Paul. Monoamine innervation of bed nucleus of stria terminalis: an electron microscopic investigation. Brain research bulletin. vol 28. issue 6. 1992-08-28. PMID:1379113. |
a comparison of axons immunoreactive (ir) for a catecholamine synthetic enzyme [tyrosine hydroxylase (th) or dopamine beta-hydroxylase (dbh) or phenylethanolamine-n-methyl transferase (pnmt)] or serotonin (5-ht) was performed. |
1992-08-28 |
2023-08-11 |
human |
| B S Mitchell, E Ahme. An immunohistochemical study of the catecholamine synthesizing enzymes and neuropeptides in the female guinea-pig uterus and vagina. The Histochemical journal. vol 24. issue 6. 1992-08-25. PMID:1353070. |
the uterus and vagina of the guinea pig have been examined, region by region, for acetylcholinesterase, tyrosine hydroxylase, dopamine beta-hydroxylase and aromatic amino acid decarboxylase activity, as well as for the neuropeptides, neuropeptide y, vasoactive intestinal peptide, substance p, enkephalin and somatostatin. |
1992-08-25 |
2023-08-11 |
Not clear |
| B S Mitchell, E Ahme. An immunohistochemical study of the catecholamine synthesizing enzymes and neuropeptides in the female guinea-pig uterus and vagina. The Histochemical journal. vol 24. issue 6. 1992-08-25. PMID:1353070. |
of the catecholamine-synthesizing enzymes, tyrosine hydroxylase and dopamine beta-hydroxylase activity was found virtually throughout the reproductive tract, whereas aromatic amino acid decarboxylase activity was restricted in its distribution. |
1992-08-25 |
2023-08-11 |
Not clear |
| L E Annett, D C Rogers, T D Hernandez, S B Dunnet. Behavioural analysis of unilateral monoamine depletion in the marmoset. Brain : a journal of neurology. vol 115 ( Pt 3). 1992-08-19. PMID:1352726. |
unilateral stereotaxic injections of 6-hydroxydopamine (6-ohda) into the nigrostriatal bundle of marmosets (callithrix jacchus) produced substantial losses of tyrosine hydroxylase immunoreactive neurons from the substantia nigra, and mean dopamine (da) depletions of 98-99% in the caudate nucleus, putamen and nucleus accumbens, and of 91-97% in frontal cortex, on the side of the lesion. |
1992-08-19 |
2023-08-11 |
monkey |
| J W Polli, R L Kincaid, J Torris, M L Billingsle. Expression of calmodulin-dependent enzymes in developing rat striatum is not affected by perturbation of dopaminergic systems. Synapse (New York, N.Y.). vol 9. issue 2. 1992-08-19. PMID:1821485. |
this observation and the demonstration that expression of several cam-dependent enzymes in developing striatum occurred with a spatial and temporal pattern similar to that seen for dopamine and tyrosine hydroxylase suggested that the nigrostriatal pathway may influence the expression of cam-binding proteins (cam-bps) during striatal development. |
1992-08-19 |
2023-08-11 |
rat |