| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Kawabat. Paraganglia of the gallbladder: a report of two cases with an immunohistochemical study. Pathology, research and practice. vol 195. issue 11. 2000-01-13. PMID:10605699. |
tyrosine hydroxylase (in two of three), dopamine beta-hydroxylase (in one of three), methionine-enkephalin (in two of three), and leucine-enkephalin (in two of three) were also positive in a small amount of the chief cells. |
2000-01-13 |
2023-08-12 |
Not clear |
| D B Carr, P O'Donnell, J P Card, S R Sesac. Dopamine terminals in the rat prefrontal cortex synapse on pyramidal cells that project to the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594085. |
to address this question, retrograde transport of an attenuated strain of pseudorabies virus (prv) from the nucleus accumbens was combined with immunoperoxidase labeling of tyrosine hydroxylase (th) to identify dopamine terminals in the pfc. |
2000-01-06 |
2023-08-12 |
rat |
| B Caronti, G Tanda, C Colosimo, S Ruggieri, C Calderaro, G Palladini, F E Pontieri, G Di Chiar. Reduced dopamine in peripheral blood lymphocytes in Parkinson's disease. Neuroreport. vol 10. issue 14. 2000-01-04. PMID:10549795. |
here we show that dopamine content and tyrosine hydroxylase immunoreactivity are reduced in peripheral blood lymphocytes (pbl) in the early stages of pd. |
2000-01-04 |
2023-08-12 |
Not clear |
| T Hida, Y Hasegawa, R Ara. Histochemical study of dopamine-degrading monoamine oxidase activity in dopaminergic neurons of rat brain. Brain research. vol 842. issue 2. 1999-12-21. PMID:10526149. |
we employed a double-labeling procedure combining immunohistochemistry for tyrosine hydroxylase (th) and enzyme histochemistry for mao activity using dopamine as a substrate. |
1999-12-21 |
2023-08-12 |
rat |
| D M Kuhn, C W Aretha, T J Gedde. Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575026. |
tyrosine hydroxylase (th) is the initial and rate-limiting enzyme in the biosynthesis of dopamine (da). |
1999-12-17 |
2023-08-12 |
Not clear |
| B B Nankova, A W Tank, E L Sabba. Transient or sustained transcriptional activation of the genes encoding rat adrenomedullary catecholamine biosynthetic enzymes by different durations of immobilization stress. Neuroscience. vol 94. issue 3. 1999-12-17. PMID:10579571. |
the impact of stress on the transcription of rat adrenal tyrosine hydroxylase and dopamine beta-hydroxylase genes was examined. |
1999-12-17 |
2023-08-12 |
rat |
| B B Nankova, A W Tank, E L Sabba. Transient or sustained transcriptional activation of the genes encoding rat adrenomedullary catecholamine biosynthetic enzymes by different durations of immobilization stress. Neuroscience. vol 94. issue 3. 1999-12-17. PMID:10579571. |
parallel changes in the steady-state messenger rna levels for tyrosine hydroxylase and dopamine beta-hydroxylase were also observed. |
1999-12-17 |
2023-08-12 |
rat |
| C Bräutigam, G C Steenbergen-Spanjers, G F Hoffmann, C Dionisi-Vici, L P van den Heuvel, J A Smeitink, R A Wever. Biochemical and molecular genetic characteristics of the severe form of tyrosine hydroxylase deficiency. Clinical chemistry. vol 45. issue 12. 1999-12-17. PMID:10585338. |
tyrosine hydroxylase (th) catalyzes the rate-limiting step in the biosynthesis of the catecholamines dopamine, norepinephrine, and epinephrine. |
1999-12-17 |
2023-08-12 |
Not clear |
| H J Choi, S Y Park, O Hwan. Differential involvement of PKA and PKC in regulation of catecholamine enzyme genes by PACAP. Peptides. vol 20. issue 7. 1999-12-16. PMID:10477081. |
roles of protein kinase a (pka) and protein kinase c (pkc) in regulation of tyrosine hydroxylase, dopamine beta-hydroxylase, and phenylethanolamine n-methyltransferase expression by pituitary adenylate cyclase-activating polypeptide (pacap) were determined in primary cultured bovine chromaffin cells. |
1999-12-16 |
2023-08-12 |
cattle |
| H J Choi, S Y Park, O Hwan. Differential involvement of PKA and PKC in regulation of catecholamine enzyme genes by PACAP. Peptides. vol 20. issue 7. 1999-12-16. PMID:10477081. |
pacap increased tyrosine hydroxylase and dopamine beta-hydroxylase activities, but slightly lowered phenylethanolamine n-methyltransferase activity, resulting in a preferential rise in norepinephrine over epinephrine. |
1999-12-16 |
2023-08-12 |
cattle |
| Y Q Wang, X D Cao, G C W. Role of dopamine receptors and the changes of the tyrosine hydroxylase mRNA in acupuncture analgesia in rats. Acupuncture & electro-therapeutics research. vol 24. issue 2. 1999-12-13. PMID:10579240. |
role of dopamine receptors and the changes of the tyrosine hydroxylase mrna in acupuncture analgesia in rats. |
1999-12-13 |
2023-08-12 |
rat |
| M Jaber, B Dumartin, C Sagné, J W Haycock, C Roubert, B Giros, B Bloch, M G Caro. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. The European journal of neuroscience. vol 11. issue 10. 1999-12-08. PMID:10564358. |
differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. |
1999-12-08 |
2023-08-12 |
mouse |
| M Jaber, B Dumartin, C Sagné, J W Haycock, C Roubert, B Giros, B Bloch, M G Caro. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. The European journal of neuroscience. vol 11. issue 10. 1999-12-08. PMID:10564358. |
in order to determine the anatomical and functional integrity of the dopaminergic system, we examined the expression of tyrosine hydroxylase (th), the rate-limiting enzyme of dopamine synthesis as well as dopa decarboxylase and vesicular monoamine transporter. |
1999-12-08 |
2023-08-12 |
mouse |
| G E Meredith, T Farrell, P Kellaghan, Y Tan, D S Zahm, S Totterdel. Immunocytochemical characterization of catecholaminergic neurons in the rat striatum following dopamine-depleting lesions. The European journal of neuroscience. vol 11. issue 10. 1999-12-08. PMID:10564366. |
following such depletions, striatal neurons immunoreactive for tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc) or dopamine appear. |
1999-12-08 |
2023-08-12 |
rat |
| N Tümer, C S Broxson, J S LaRochelle, P J Scarpac. Induction of tyrosine hydroxylase and neuropeptide Y by carbachol: modulation with age. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 54. issue 10. 1999-12-06. PMID:10568524. |
this may be related to the increased basal levels of dopamine beta-hydroxylase (dbetah) and tyrosine hydroxylase (th) mrna levels and th enzyme activity in the adrenal medulla of senescent compared with younger animals. |
1999-12-06 |
2023-08-12 |
rat |
| B Ferger, P Teismann, C D Earl, K Kuschinsky, W H Oerte. Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 3. 1999-12-03. PMID:10543426. |
analysis of striatal dopamine and metabolites as well as immunostaining for tyrosine hydroxylase of nigral sections was performed 7 days after mptp treatment. |
1999-12-03 |
2023-08-12 |
mouse |
| E C Mallard, A Rehn, S Rees, M Tolcos, D Copolo. Ventriculomegaly and reduced hippocampal volume following intrauterine growth-restriction: implications for the aetiology of schizophrenia. Schizophrenia research. vol 40. issue 1. 1999-11-30. PMID:10541002. |
in contrast, there were no significant alterations in the optical density of tyrosine hydroxylase (th), a rate-limiting enzyme in the biosynthesis of catecholamines and the dopamine transporter (dat) in the striatum in growth-restricted animals compared with controls. |
1999-11-30 |
2023-08-12 |
Not clear |
| E D Clarkson, J Edwards-Prasad, C R Freed, K N Prasa. Immortalized dopamine neurons: A model to study neurotoxicity and neuroprotection. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 222. issue 2. 1999-11-30. PMID:10564540. |
recently, a clonal line of immortalized dopamine (da) neurons (1rb3an27), which expresses varying levels of tyrosine hydroxylase, dopamine transporter, neuron specific enolase, and nestin, was established. |
1999-11-30 |
2023-08-12 |
rat |
| M S Szczypka, M A Rainey, D S Kim, W A Alaynick, B T Marck, A M Matsumoto, R D Palmite. Feeding behavior in dopamine-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 21. 1999-11-24. PMID:10518589. |
mice that cannot make dopamine (da), a condition caused by the selective inactivation of tyrosine hydroxylase in dopaminergic neurons, are born normal but gradually become hypoactive and hypophagic, and die at 3 weeks of age. |
1999-11-24 |
2023-08-12 |
mouse |
| L Serova, E Danailov, F Chamas, E L Sabba. Nicotine infusion modulates immobilization stress-triggered induction of gene expression of rat catecholamine biosynthetic enzymes. The Journal of pharmacology and experimental therapeutics. vol 291. issue 2. 1999-11-24. PMID:10525113. |
multiple injections of nicotine bitartrate (5 mg/kg) elevated mrna levels for the catecholamine biosynthetic enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase, and of preproneuropeptide y in rat adrenal medulla more than did 1 mg/kg of nicotine bitartrate. |
1999-11-24 |
2023-08-12 |
rat |