| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Arai, K Horiike, Y Hasegaw. Dopamine-degrading activity of monoamine oxidase in locus coeruleus and dorsal raphe nucleus neurons. A histochemical study in the rat. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696061. |
our new method, designed to minimise the non-enzymatic oxidation of dopamine, was applied in combination with tyrosine hydroxylase (th) and serotonin immunohistochemistry. |
1999-05-19 |
2023-08-12 |
rat |
| A Jansson, M Goldstein, B Tinner, M Zoli, J H Meador-Woodruff, J Y Lew, A I Levey, S Watson, L F Agnati, K Fux. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. vol 89. issue 2. 1999-05-07. PMID:10077329. |
on the distribution patterns of d1, d2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. |
1999-05-07 |
2023-08-12 |
rat |
| A Jansson, M Goldstein, B Tinner, M Zoli, J H Meador-Woodruff, J Y Lew, A I Levey, S Watson, L F Agnati, K Fux. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. vol 89. issue 2. 1999-05-07. PMID:10077329. |
the distribution of dopamine d1 and d2 receptor immunoreactivities in the nucleus accumbens and the olfactory tubercle of adult and postnatal male rats were compared with the distribution of tyrosine hydroxylase and dopamine transporter immunoreactivities. |
1999-05-07 |
2023-08-12 |
rat |
| A Jansson, M Goldstein, B Tinner, M Zoli, J H Meador-Woodruff, J Y Lew, A I Levey, S Watson, L F Agnati, K Fux. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. vol 89. issue 2. 1999-05-07. PMID:10077329. |
however, the major finding in this study was, following a more detailed analysis in coronal sections of the shell part of the nucleus accumbens, the existence of nerve cell patches of strong d1 receptor immunoreactivity associated with low d2 receptor, dopamine transporter and tyrosine hydroxylase immunoreactivities. |
1999-05-07 |
2023-08-12 |
rat |
| A Jansson, M Goldstein, B Tinner, M Zoli, J H Meador-Woodruff, J Y Lew, A I Levey, S Watson, L F Agnati, K Fux. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. vol 89. issue 2. 1999-05-07. PMID:10077329. |
these patches were mainly surrounded by areas of strong d2 receptor, tyrosine hydroxylase and dopamine transporter immunoreactivities and could be found also in the olfactory tubercle. |
1999-05-07 |
2023-08-12 |
rat |
| A I Brooks, C A Chadwick, H A Gelbard, D A Cory-Slechta, H J Federof. Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain research. vol 823. issue 1-2. 1999-05-07. PMID:10095006. |
the data indicate that paraquat like mptp elicits a dose-dependent decrease in substantia nigra dopaminergic neurons assessed by a fluoro-gold prelabeling method, a decline in striatal dopamine nerve terminal density assessed by measurement of tyrosine hydroxylase immunoreactivity; and neurobehavioral syndrome characterized by reduced ambulatory activity. |
1999-05-07 |
2023-08-12 |
mouse |
| A Nakashima, K Mori, T Suzuki, H Kurita, M Otani, T Nagatsu, A Ot. Dopamine inhibition of human tyrosine hydroxylase type 1 is controlled by the specific portion in the N-terminus of the enzyme. Journal of neurochemistry. vol 72. issue 5. 1999-05-06. PMID:10217296. |
dopamine inhibition of human tyrosine hydroxylase type 1 is controlled by the specific portion in the n-terminus of the enzyme. |
1999-05-06 |
2023-08-12 |
human |
| A Nakashima, K Mori, T Suzuki, H Kurita, M Otani, T Nagatsu, A Ot. Dopamine inhibition of human tyrosine hydroxylase type 1 is controlled by the specific portion in the N-terminus of the enzyme. Journal of neurochemistry. vol 72. issue 5. 1999-05-06. PMID:10217296. |
tyrosine hydroxylase (th), which converts l-tyrosine to l-dopa, is a rate-limiting enzyme in the biosynthesis of catecholamines; its activity is regulated by feedback inhibition by catecholamine products including dopamine. |
1999-05-06 |
2023-08-12 |
human |
| R A Furlong, J S Rubinsztein, L Ho, C Walsh, T A Coleman, W J Muir, E S Paykel, D H Blackwood, D C Rubinsztei. Analysis and metaanalysis of two polymorphisms within the tyrosine hydroxylase gene in bipolar and unipolar affective disorders. American journal of medical genetics. vol 88. issue 1. 1999-05-03. PMID:10050974. |
tyrosine hydroxylase (th) is the rate-limiting enzyme in the synthesis of dopamine and noradrenaline. |
1999-05-03 |
2023-08-12 |
Not clear |
| M Jaber, B Bloch, M G Caron, B Giro. [Behavioral, cellular and molecular consequences of the dopamine transporter gene inactivation]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 192. issue 6. 1999-05-03. PMID:10101608. |
we investigated the regulation of tyrosine hydroxylase (th), the rate limiting enzyme of dopamine synthesis, and found that this enzyme is regulated at the levels of mrna, protein, trafficking as well as in its regional, cellular and subcellular organization. |
1999-05-03 |
2023-08-12 |
mouse |
| M J Prud'homme, E Houdeau, R Serghini, Y Tillet, M Schemann, J P Roussea. Small intensely fluorescent cells of the rat paracervical ganglion synthesize adrenaline, receive afferent innervation from postganglionic cholinergic neurones, and contain muscarinic receptors. Brain research. vol 821. issue 1. 1999-04-22. PMID:10064798. |
immunolabelling for tyrosine hydroxylase (th), dopamine beta-hydroxylase and phenylethanolamine-n-methyl transferase (pnmt) occurred in all sif cells of the pcg, thus demonstrating the presence of all the enzymes required for adrenaline biosynthesis. |
1999-04-22 |
2023-08-12 |
rat |
| W S Neckameye. Dopamine modulates female sexual receptivity in Drosophila melanogaster. Journal of neurogenetics. vol 12. issue 2. 1999-04-19. PMID:10197160. |
newly eclosed drosophila melanogaster flies were systemically depleted of dopamine by feeding an inhibitor of the biosynthetic enzyme, tyrosine hydroxylase, and analyzed for abnormalities in courtship behavior. |
1999-04-19 |
2023-08-12 |
drosophila_melanogaster |
| W S Neckameye. Dopamine modulates female sexual receptivity in Drosophila melanogaster. Journal of neurogenetics. vol 12. issue 2. 1999-04-19. PMID:10197160. |
female receptivity may be regulated via interactions with hormonal pathways, since depletion of dopamine levels via inhibition of tyrosine hydroxylase activity in drosophila melanogaster adult females has established that dopamine is required for normal ovarian maturation and fecundity. |
1999-04-19 |
2023-08-12 |
drosophila_melanogaster |
| W S Joo, B K Jin, C W Park, S H Maeng, Y S Ki. Melatonin increases striatal dopaminergic function in 6-OHDA-lesioned rats. Neuroreport. vol 9. issue 18. 1999-04-13. PMID:9926859. |
compared with sham-operated controls and expressed as a ratio relative to the contralateral side, there was an increase in the lipid peroxidation product malondialdehyde (mda, 142%) and a significant reduction in tyrosine hydroxylase (th) enzyme activity (28%) and dopamine (da, 32%) and its metabolite dihydroxyphenylacetic acid (dopac, 50%) 2 weeks after 6-ohda injection. |
1999-04-13 |
2023-08-12 |
rat |
| M Tor. Biological research on schizophrenia. Psychiatry and clinical neurosciences. vol 52 Suppl. 1999-04-07. PMID:9895138. |
measurement of tyrosine hydroxylase activity and dopamine d2 receptor in the schizophrenic brain provided evidence of hyperdopaminergia. |
1999-04-07 |
2023-08-12 |
Not clear |
| E Bezard, C E Gross, M C Fournier, S Dovero, B Bloch, M Jabe. Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter. Experimental neurology. vol 155. issue 2. 1999-04-07. PMID:10072302. |
for this we have used tyrosine hydroxylase immunoreactivity (th-ir) labeling of dopamine cells of the substantia nigra compacta in wild-type, heterozygote, and homozygote mice that were given either saline or mptp treatments (two ip injections of 30 mg/kg, 10 h apart). |
1999-04-07 |
2023-08-12 |
mouse |
| G T Ramesh, A L Jadha. Region-specific alterations in tyrosine hydroxylase activity in rats exposed to lead. Molecular and cellular biochemistry. vol 189. issue 1-2. 1999-03-23. PMID:9879649. |
previous studies from our laboratory showed that subchronic exposure to low levels of pb resulted in significant decrease in dopamine (da) content, attenuation of stimulus-induced release of da in the dopaminergic projection area of nucleus accumbens (na), and alterations in tyrosine hydroxylase (th) activity in rat whole brain homogenates. |
1999-03-23 |
2023-08-12 |
rat |
| B B Nankova, S Y Fuchs, L I Serova, Z Ronai, D Wild, E L Sabba. Selective in vivo stimulation of stress-activated protein kinase in different rat tissues by immobilization stress. Stress (Amsterdam, Netherlands). vol 2. issue 4. 1999-03-12. PMID:9876260. |
in adrenal medulla, the activation of jnk by single immobilization stress is correlated with increased transcription of stress-responsive genes, tyrosine hydroxylase and dopamine beta-hydroxylase. |
1999-03-12 |
2023-08-12 |
rat |
| Y Xu, A H Stokes, R Roskoski, K E Vran. Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. Journal of neuroscience research. vol 54. issue 5. 1999-03-11. PMID:9843160. |
dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. |
1999-03-11 |
2023-08-12 |
Not clear |
| Y Xu, A H Stokes, R Roskoski, K E Vran. Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. Journal of neuroscience research. vol 54. issue 5. 1999-03-11. PMID:9843160. |
one of the potential targets in brain for dopamine quinone damage is tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis. |
1999-03-11 |
2023-08-12 |
Not clear |