| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Lewis Liu, Jaewoong Moo. A novel NADPH-dependent aldehyde reductase gene from Saccharomyces cerevisiae NRRL Y-12632 involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion. Gene. vol 446. issue 1. 2009-08-31. PMID:19577617. |
based on the deduced amino acid sequence and the most conserved functional motif analyses including closely related reductases from five other yeast species to this date, ygl157w was identified as a member of the subclass 'intermediate' of the sdr (short-chain dehydrogenase/reductase) superfamily with the following typical characteristics: the most conserved catalytic site to lie at tyr(169)-x-x-x-lys(173); an indispensable reduction catalytic triad at ser(131), tyr(169), and lys(173), and an approved cofactor-binding motif at gly(11)-x-x-gly(14)-x-x-ala(17) near the n-terminus. |
2009-08-31 |
2023-08-12 |
Not clear |
| Dustin K Williams, Clare Stokes, Nicole A Horenstein, Roger L Papk. Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site. The Journal of pharmacology and experimental therapeutics. vol 330. issue 1. 2009-07-27. PMID:19339660. |
alpha7 receptors with trp55 mutated to gly or tyr became less responsive to 4oh-gts-21, whereas mutation of the homologous trp57 in beta2 to gly, tyr, phe, or ala resulted in alpha4beta2 receptors that showed increased responses to 4oh-gts-21. |
2009-07-27 |
2023-08-12 |
human |
| Denise Wätzlich, Markus J Bröcker, Frank Uliczka, Markus Ribbe, Simone Virus, Dieter Jahn, Jürgen Mose. Chimeric nitrogenase-like enzymes of (bacterio)chlorophyll biosynthesis. The Journal of biological chemistry. vol 284. issue 23. 2009-07-13. PMID:19336405. |
surface-exposed residues tyr(127) of subunit chll, leu(70) and val(107) of subunit chln, and gly(66) of subunit chlb were found essential for p. marinus dpor activity. |
2009-07-13 |
2023-08-12 |
Not clear |
| Yawei Kong, Gu Jing, Zhenguang Yan, Changzhong Li, Ningping Gong, Fangjie Zhu, Dongxian Li, Yaorun Zhang, Guilan Zheng, Hongzhong Wang, Liping Xie, Rongqing Zhan. Cloning and characterization of Prisilkin-39, a novel matrix protein serving a dual role in the prismatic layer formation from the oyster Pinctada fucata. The Journal of biological chemistry. vol 284. issue 16. 2009-06-18. PMID:19233851. |
prisilkin-39 is a highly repetitive protein with an unusual composition of gly, tyr, and ser residues. |
2009-06-18 |
2023-08-12 |
Not clear |
| James M Kovacs, Jonathan P Hannan, Elan Z Eisenmesser, V Michael Holer. Mapping of the C3d ligand binding site on complement receptor 2 (CR2/CD21) using nuclear magnetic resonance and chemical shift analysis. The Journal of biological chemistry. vol 284. issue 14. 2009-06-01. PMID:19164292. |
with regard to c3d, the binding surface includes regions of scr1, scr2, and the inter-scr linker, specifically residues arg(13), tyr(16), arg(28), tyr(29), ser(32), thr(34), lys(48), asp(56), lys(57), tyr(68), arg(83), gly(84), asn(101), asn(105), and ser(109). |
2009-06-01 |
2023-08-12 |
Not clear |
| James M Kovacs, Jonathan P Hannan, Elan Z Eisenmesser, V Michael Holer. Mapping of the C3d ligand binding site on complement receptor 2 (CR2/CD21) using nuclear magnetic resonance and chemical shift analysis. The Journal of biological chemistry. vol 284. issue 14. 2009-06-01. PMID:19164292. |
titration with c3dp1 yielded chemical shift changes (arg(13), tyr(16), thr(34), lys(48), asp(56), lys(57), tyr(68), arg(83), gly(84), asn(105), and ser(109)) overlapping with c3d, indicating that c3dp1 interacts at the same cr2 site as c3d. |
2009-06-01 |
2023-08-12 |
Not clear |
| Akihito Ochiai, Takafumi Itoh, Bunzo Mikami, Wataru Hashimoto, Kousaku Murat. Structural determinants responsible for substrate recognition and mode of action in family 11 polysaccharide lyases. The Journal of biological chemistry. vol 284. issue 15. 2009-05-20. PMID:19193638. |
the yesw amino acid residues such as asn(152), asp(172), asn(532), gly(533), thr(534), and tyr(595) in the active cleft bind to rhamnose molecules through hydrogen bonds and van der waals contacts. |
2009-05-20 |
2023-08-12 |
Not clear |
| Ahmad B Maarouf, Nan Sheng, Jingxin Chen, Katie L Winarski, Sora Okumura, Marcelo D Carattino, Cary R Boyd, Thomas R Kleyman, Shaohu Shen. Novel determinants of epithelial sodium channel gating within extracellular thumb domains. The Journal of biological chemistry. vol 284. issue 12. 2009-05-14. PMID:19158091. |
fourteen substitutions (ala, arg, asp, cys, gln, glu, his, ile, phe, pro, ser, thr, tyr, and val) significantly suppressed na(+) self-inhibition, whereas three mutations (asn, gly, and leu) moderately enhanced the inhibition. |
2009-05-14 |
2023-08-12 |
mouse |
| Zhao-Zhen Ren, Yuan Zheng, Mi Sun, Jun-Zhong Liu, Yue-Jun Wan. [Purification and properties of an antimicrobial substance from marine Brevibacillus laterosporus Lh-1]. Wei sheng wu xue bao = Acta microbiologica Sinica. vol 47. issue 6. 2009-05-05. PMID:18271253. |
amino acid analysis of the purified r-1 showed that it was composed of leu, tyr, val, ile, lys, gly, met, ser and ala. |
2009-05-05 |
2023-08-12 |
Not clear |
| I Luque, A Echeita, J León, S Herrera-León, C Tarradas, R González-Sanz, B Huerta, R J Astorg. Salmonella Indiana as a cause of abortion in ewes: Genetic diversity and resistance patterns. Veterinary microbiology. vol 134. issue 3-4. 2009-04-14. PMID:18823722. |
among the r-nx strains, a substitution of gly to cys at position 81 (gly81àcys) of the gyra gene in 10 strains isolated from wild birds and ovine foetuses, and of asp to tyr at position 87 (asp87àtyr) in one strain isolated from ewe faeces, were revealed by sequencing the gene. |
2009-04-14 |
2023-08-12 |
pigeon |
| Yanqiang Zhang, Suojiang Zhang, Xingmei Lu, Qing Zhou, Wei Fan, XiangPing Zhan. Dual amino-functionalised phosphonium ionic liquids for CO2 capture. Chemistry (Weinheim an der Bergstrasse, Germany). vol 15. issue 12. 2009-04-01. PMID:19185037. |
a series of 20 dual amino-functionalised phosphonium ionic liquids, (3-aminopropyl)tributylphosphonium amino acid salts ([ap(4443)][aa], in which [aa](-) = [ala](-), [arg](-), [asn](-), [asp](-), [cys](-), [gln](-), [glu](-), [gly](-), [his](-), [ile](-), [leu](-), [lys](-), [met](-), [phe](-), [pro](-), [ser](-), [thr](-), [trp](-), [tyr](-) and [val](-)), has been prepared. |
2009-04-01 |
2023-08-12 |
Not clear |
| Cynthia Perrine, Tongzhong Ju, Richard D Cummings, Thomas A Gerke. Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-alpha-GalNAc beta 3 galactosyltransferase (T-synthase). Glycobiology. vol 19. issue 3. 2009-03-24. PMID:19073881. |
from these studies, elevated preferences for gly at the +1 position with moderately high preferences for phe and tyr in the +3 position relative to the acceptor thr-o-galnac were found. |
2009-03-24 |
2023-08-12 |
human |
| Yoshinobu Shiose, Hiroshi Kuga, Hitoshi Ohki, Masahiro Ikeda, Fumiyoshi Yamashita, Mitsuru Hashid. Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates. Bioconjugate chemistry. vol 20. issue 1. 2009-03-23. PMID:19090781. |
225 conjugates of carboxymethyldextran polyalcohol (cm-dex-pa) as water-soluble carrier and a dansyl derivative (n-(4-aminobutyl)-5-(dimethylamino)-1-naphthalenesulfonamide, dns) as the model drug linked with different tetrapeptide spacers (gly-gly-p(2)-p(1), p(2), p(1): ala, asn, gly, cit, gln, ile, leu, met, phe, pro, ser, thr, trp, tyr, and val) were combinatorially synthesized. |
2009-03-23 |
2023-08-12 |
mouse |
| Vinitha R Pai, V Rajaram, Shveta Bisht, B S Bhavani, N Appaji Rao, M R N Murthy, H S Savithr. Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding. The Biochemical journal. vol 418. issue 3. 2009-03-16. PMID:19046138. |
in the present study, the residues asn(341), tyr(60) and phe(351), which are likely to influence thf binding, were mutated to alanine, alanine and glycine respectively, to elucidate the role of these residues in thf-dependent and -independent reactions catalysed by shmt. |
2009-03-16 |
2023-08-12 |
Not clear |
| Priscila Randazzo-Moura, L A Ponce-Soto, Léa Rodrigues-Simioni, Sérgio Marangon. Structural characterization and neuromuscular activity of a new Lys49 phospholipase A(2) homologous (Bp-12) isolated from Bothrops pauloensis snake venom. The protein journal. vol 27. issue 6. 2009-01-06. PMID:18769889. |
the amino acids composition showed that bp-12 presented high content of lys, tyr, gly, pro, and 14 half-cys residues, typical of a basic pla(2). |
2009-01-06 |
2023-08-12 |
mouse |
| Sudha Anand, Anand Anbarasu, Rao Sethumadhava. Influence of C-H...pi hydrogen bonds in interleukins. In silico biology. vol 8. issue 3-4. 2008-12-22. PMID:19032161. |
significant contribution to c-h...pi interactions was only from asp, gly, his, lys, phe, pro, ser, thr, trp and tyr in interleukins. |
2008-12-22 |
2023-08-12 |
Not clear |
| Lisa A Bruce, Jeffrey A Sigman, Danica Randall, Scott Rodriguez, Michelle M Song, Yi Dai, Donald E Elmore, Amanda Pabon, Marc J Glucksman, Adele J Wolfso. Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection. The FEBS journal. vol 275. issue 22. 2008-12-10. PMID:18959747. |
this study describes mutant forms of thimet oligopeptidase in which gly or tyr residues in the 599-611 loop region were replaced, individually and in combination, to elucidate the mechanism of substrate selection by this enzyme. |
2008-12-10 |
2023-08-12 |
cat |
| Lisa A Bruce, Jeffrey A Sigman, Danica Randall, Scott Rodriguez, Michelle M Song, Yi Dai, Donald E Elmore, Amanda Pabon, Marc J Glucksman, Adele J Wolfso. Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection. The FEBS journal. vol 275. issue 22. 2008-12-10. PMID:18959747. |
this distinction suggests that the role of gly residues in the loop is to properly orientate these tyr residues in order to accommodate varying substrate structures. |
2008-12-10 |
2023-08-12 |
cat |
| Mina Jahandideh, Seyyed Mohsen Hosseini Barkooie, Samad Jahandideh, Parviz Abdolmaleki, Mohammad Mehdi Movahedi, Somayyeh Hoseini, Ebrahim Barzegari Asadabadi, Fatemeh Javani Jouni, Zahra Karami, Nader Hodjati Firoozabad. Elucidating the protein cold-adaptation: Investigation of the parameters enhancing protein psychrophilicity. Journal of theoretical biology. vol 255. issue 1. 2008-12-05. PMID:18718477. |
in addition, our results provided new quantitative information about the trends in the substitution preference of ile, phe, tyr, lys, arg, his, glu and leu with most of amino acids and substitution avoidance of gly, thr and ala with most of amino acids. |
2008-12-05 |
2023-08-12 |
Not clear |
| Olivier R Bolduc, Jean-François Masso. Monolayers of 3-mercaptopropyl-amino acid to reduce the nonspecific adsorption of serum proteins on the surface of biosensors. Langmuir : the ACS journal of surfaces and colloids. vol 24. issue 20. 2008-11-13. PMID:18823086. |
the nonspecific adsorption of serum proteins on the 3-mpa-amino acids increases in the following order: asp < asn < ser < met < glu < gln < thr < gly < his < cys < arg < phe < trp < val < pro < ile < leu < ala < tyr. |
2008-11-13 |
2023-08-12 |
cattle |