| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reinaldo Fraga Vidal, Claire Moulis, Pierre Escalier, Magali Remaud-Siméon, Pierre Monsa. Isolation of a gene from Leuconostoc citreum B/110-1-2 encoding a novel dextransucrase enzyme. Current microbiology. vol 62. issue 4. 2011-07-18. PMID:21229247. |
however, the variable region is longer than in other gtfs (by 100 amino acids) and two apy repeats (a 79 residue long motif with a high number of conserved glycine and aromatic residues, characterized by the presence of the three consecutive residues ala, pro, and tyr) were identified in the glucan binding domain. |
2011-07-18 |
2023-08-12 |
Not clear |
| Yunpeng Ye, Baogang Xu, Gregory V Nikiforovich, Sharon Bloch, Samuel Achilef. Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging. Bioorganic & medicinal chemistry letters. vol 21. issue 7. 2011-07-11. PMID:21349709. |
this was confirmed experimentally, which further showed that substitution of gly with pro, val and tyr in 1 remarkably hampered the α(v)β(3) binding. |
2011-07-11 |
2023-08-12 |
Not clear |
| Alessia P M Barbagallo, Zilai Wang, Hui Zheng, Luciano D'Adami. A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. The Journal of biological chemistry. vol 286. issue 11. 2011-05-16. PMID:21266574. |
to dissect the functions of this sequence in vivo, we created an app knock-in allele mutating tyr(682) to gly (y682g). |
2011-05-16 |
2023-08-12 |
mouse |
| Colin T Mant, Dziuleta Cepeniene, Robert S Hodge. Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns. Journal of separation science. vol 33. issue 19. 2011-02-10. PMID:21038458. |
thus, we have designed and synthesized two series of synthetic peptide standards with the sequence gly-gly-leu-gly-gly-ala-leu-gly-x-leu-lys-lys-amide, where the n-terminal either contains a free α-amino group (amc series) or is n(α)-acetylated (acc series) and where position x is substituted by gly, ala, val, ile, phe or tyr. |
2011-02-10 |
2023-08-12 |
Not clear |
| Colin T Mant, Dziuleta Cepeniene, Robert S Hodge. Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns. Journal of separation science. vol 33. issue 19. 2011-02-10. PMID:21038458. |
these represent series of peptides with single substitutions of n-alkyl (glytyr) and a side-chain also with polar character (tyr). |
2011-02-10 |
2023-08-12 |
Not clear |
| Z Sheng, M Prorok, F J Castellin. Specific determinants of conantokins that dictate their selectivity for the NR2B subunit of N-methyl-D-aspartate receptors. Neuroscience. vol 170. issue 3. 2011-01-11. PMID:20688135. |
tyr at position 5 broadens the nr2 selectivity, and recovery of nr2b selectivity in tyr5 peptides was achieved by incorporating ala or gly at position 8. |
2011-01-11 |
2023-08-12 |
human |
| Akikazu Murakami, Yuka Takahashi, Miyuki Nishimura, Takeyuki Shimizu, Takachika Azum. The amino acid residue at position 95 and the third CDR region in the H chain determine the ceiling affinity and the maturation pathway of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody. Molecular immunology. vol 48. issue 1-3. 2011-01-03. PMID:20961619. |
two groups of anti-(4-hydroxy-3-nitrophenyl)acetyl (np) abs each possessing a different amino acid, tyr or gly, at position 95, appeared respectively at early and late stages of immunization. |
2011-01-03 |
2023-08-12 |
Not clear |
| Adrien Lugari, Stephane Betzi, Etienne Decroly, Emmanuel Bonnaud, Aurélie Hermant, Jean-Claude Guillemot, Claire Debarnot, Jean-Paul Borg, Mickaël Bouvet, Bruno Canard, Xavier Morelli, Patrick Lécin. Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16. The Journal of biological chemistry. vol 285. issue 43. 2010-11-24. PMID:20699222. |
alanine-scanning mutagenesis, bioinformatics, and molecular modeling were used to identify several "hot spots," such as val(42), met(44), ala(71), lys(93), gly(94), and tyr(96), forming a continuous protein-protein surface of about 830 Å(2), bearing very conserved amino acids among coronaviruses. |
2010-11-24 |
2023-08-12 |
human |
| Eva J Helmerhorst, Georges Traboulsi, Erdjan Salih, Frank G Oppenhei. Mass spectrometric identification of key proteolytic cleavage sites in statherin affecting mineral homeostasis and bacterial binding domains. Journal of proteome research. vol 9. issue 10. 2010-10-29. PMID:20731414. |
the main and primary cleavage sites were located in the n-terminal half of statherin, specifically after arg(9), arg(10), and arg(13); after phe(14) and tyr(18); and after gly(12), gly(15), gly(17) and gly(19) while the c-terminal half of statherin remained intact. |
2010-10-29 |
2023-08-12 |
human |
| Shuji Ohno, Masanori Ohta, Yoko Honda, Shizuo Nakaji. Sequence and expression of 11beta-hydroxysteroid dehydrogenase type 1 cDNA cloned from pig testis. Molecular and cellular biochemistry. vol 338. issue 1-2. 2010-10-21. PMID:20020184. |
amino acid sequence, deduced from cloned cdna, also had a conserved triad of catalytically important ser, tyr and lys residues for the short-chain dehydrogenase/reductase family, a membrane-spanning domain consisting of hydrophobic amino acid and a glycine motif in the cofactor binding region. |
2010-10-21 |
2023-08-12 |
human |
| Tae-Hyun Kim, Shite Sebastian, Jessica T Pinkham, Robin A Ross, LeeAnn T Blalock, Dennis L Kaspe. Characterization of the O-antigen polymerase (Wzy) of Francisella tularensis. The Journal of biological chemistry. vol 285. issue 36. 2010-10-05. PMID:20605777. |
site-directed mutagenesis based on protein homology and topology, which was carried out to locate a catalytic residue of the protein, showed that modification of specific residues (gly(176), asp(177), gly(323), and tyr(324)) leads to a loss of o-ps polymerization. |
2010-10-05 |
2023-08-12 |
Not clear |
| Sara Birtalan, Robert D Fisher, Sachdev S Sidh. The functional capacity of the natural amino acids for molecular recognition. Molecular bioSystems. vol 6. issue 7. 2010-09-27. PMID:20383388. |
nine other residue types (phe, leu, ile, asn, thr, pro, cys, ala, and gly) were found to be ineffective as replacements for tyr. |
2010-09-27 |
2023-08-12 |
Not clear |
| Sara Birtalan, Robert D Fisher, Sachdev S Sidh. The functional capacity of the natural amino acids for molecular recognition. Molecular bioSystems. vol 6. issue 7. 2010-09-27. PMID:20383388. |
by replacing ser with gly or ala, we found that gly is as effective as ser for providing conformational flexibility that allows bulky tyr residues to achieve optimal binding contacts, while ala is less effective but still functional in this capacity. |
2010-09-27 |
2023-08-12 |
Not clear |
| Min S Kang, Aeran Kim, Byeong Y Jung, Moon Her, Wooseog Jeong, Young M Cho, Jae Y Oh, Young J Lee, Jun H Kwon, Yong K Kwo. Characterization of antimicrobial resistance of recent Salmonella enterica serovar Gallinarum isolates from chickens in South Korea. Avian pathology : journal of the W.V.P.A. vol 39. issue 3. 2010-09-23. PMID:20544426. |
forty-two quinolone-resistant isolates, of which the quinolone resistance-determining regions of the gyra genes were sequenced, contained a substitution of a ser to a phe or tyr at position 83 (71.4%), or a substitution of an asp to an asn, gly, or tyr at position 87 (28.6%). |
2010-09-23 |
2023-08-12 |
Not clear |
| James M Kovacs, Jonathan P Hannan, Elan Z Eisenmesser, V Michael Holer. Biophysical investigations of complement receptor 2 (CD21 and CR2)-ligand interactions reveal amino acid contacts unique to each receptor-ligand pair. The Journal of biological chemistry. vol 285. issue 35. 2010-09-17. PMID:20558730. |
with regard to gp350, the binding region of cr2 is primarily focused on scr1 and the inter-scr linker, specifically residues asn(11), arg(13), ala(22), arg(28), ser(32), arg(36), lys(41), lys(57), tyr(64), lys(67), tyr(68), arg(83), gly(84), and arg(89). |
2010-09-17 |
2023-08-12 |
human |
| James M Kovacs, Jonathan P Hannan, Elan Z Eisenmesser, V Michael Holer. Biophysical investigations of complement receptor 2 (CD21 and CR2)-ligand interactions reveal amino acid contacts unique to each receptor-ligand pair. The Journal of biological chemistry. vol 285. issue 35. 2010-09-17. PMID:20558730. |
with regard to ifnalpha, the binding is similar to the cr2-c3d interaction with specific residues being arg(13), tyr(16), arg(28), ser(42), lys(48), lys(50), tyr(68), arg(83), gly(84), and arg(89). |
2010-09-17 |
2023-08-12 |
human |
| Jorge P López-Alonso, Miguel A Pardo-Cea, Irene Gómez-Pinto, Irene Fernández, Avijit Chakrabartty, Enrique Pedroso, Carlos González, Douglas V Laurent. Putative one-pot prebiotic polypeptides with ribonucleolytic activity. Chemistry (Weinheim an der Bergstrasse, Germany). vol 16. issue 18. 2010-08-18. PMID:20232309. |
kia7, a peptide with a highly restricted set of amino acids (lys, ile, ala, gly and tyr), adopts a specifically folded structure. |
2010-08-18 |
2023-08-12 |
Not clear |
| Jorge P López-Alonso, Miguel A Pardo-Cea, Irene Gómez-Pinto, Irene Fernández, Avijit Chakrabartty, Enrique Pedroso, Carlos González, Douglas V Laurent. Putative one-pot prebiotic polypeptides with ribonucleolytic activity. Chemistry (Weinheim an der Bergstrasse, Germany). vol 16. issue 18. 2010-08-18. PMID:20232309. |
some amino acids, including lys, ile, ala, gly and his, form under the same putative prebiotic conditions, whereas different conditions are needed for producing tyr, phe and trp. |
2010-08-18 |
2023-08-12 |
Not clear |
| R Priyadharshini, D Hemalatha, P Gunasekara. Role of Val289 residue in the alpha-amylase of Bacillus amyloliquefaciens MTCC 610: an analysis by site directed mutagenesis. Journal of microbiology and biotechnology. vol 20. issue 3. 2010-07-27. PMID:20372028. |
in these mutant alpha-amylases, val289 was substituted with ile, tyr, phe, leu, gly, pro, ser, arg, glu, and asp. |
2010-07-27 |
2023-08-12 |
Not clear |
| T A Woyengo, E Kiarie, C M Nyachot. Metabolizable energy and standardized ileal digestible amino acid contents of expeller-extracted canola meal fed to broiler chicks. Poultry science. vol 89. issue 6. 2010-07-08. PMID:20460665. |
expeller-extracted canola meal had greater (p<0.05) standardized ileal digestible contents of gly, leu, ser, thr, asp, and glu and tended to have greater (p<0.10) standardized ileal digestible contents of ile, lys, phe, ala, and tyr than secm. |
2010-07-08 |
2023-08-12 |
chicken |