| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marilda Rigobello-Masini, José C P Penteado, Cleber W Liria, M Terêsa M Miranda, Jorge C Masin. Implementing stepwise solvent elution in sequential injection chromatography for fluorimetric determination of intracellular free amino acids in the microalgae Tetraselmis gracilis. Analytica chimica acta. vol 628. issue 2. 2008-11-12. PMID:18929000. |
at a flow rate of 10 microl s(-1) a 25 mm long-column was able to separate aspartic acid (asp), glutamic acid (glu), asparagine (asn), serine (ser), glutamine (gln), glycine (gly), threonine (thr), citruline (ctr), arginine (arg), alanine (ala), tyrosine (tyr), phenylalanine (phe), ornithine (orn) and lysine (lys) with resolution >1.2 as well as methionine (met) and valine (val) with resolution of 0.6. |
2008-11-12 |
2023-08-12 |
Not clear |
| Irena Jelínkova, Vojtech Vávra, Marie Jindrichova, Tomas Obsil, Hana W Zemkova, Hana Zemkova, Stanko S Stojilkovi. Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin. Pflugers Archiv : European journal of physiology. vol 456. issue 5. 2008-10-27. PMID:18427835. |
in contrast, the ivm-independent hits met(31), tyr(42), gly(45), val(49), gly(340), leu(343), ala(344), gly(347), thr(350), asp(354), and val(357) map on the opposite side of their helices, probably facing the pore of receptor or protein and playing important roles in gating. |
2008-10-27 |
2023-08-12 |
rat |
| Marija L Mihajlovic, Petar M Mitrasinovi. Another look at the molecular mechanism of the resistance of H5N1 influenza A virus neuraminidase (NA) to oseltamivir (OTV). Biophysical chemistry. vol 136. issue 2-3. 2008-09-26. PMID:18584938. |
using the crystal structure of the complex of h5n1 na with otv (pdb id: 2hu0) as the starting point, the question, how mutations at his274 by both smaller side chain (gly, ser, asn, gln) and larger side chain (phe, tyr) residues influence the sensitivity of n1 to oseltamivir, was addressed and correlated with the experimental data. |
2008-09-26 |
2023-08-12 |
Not clear |
| N V Mozhina, O A Burmistrova, D V Pupov, G N Rudenskaia, Ia E Dunaevskiĭ, I V Demidiuk, S V Kostro. [Isolation and properties of cysteine protease from Serratia proteamaculans 94]. Bioorganicheskaia khimiia. vol 34. issue 3. 2008-09-12. PMID:18672676. |
unlike gingipains r, spcp displays a double substrate specificity and cleaves bonds formed by carboxylic groups of arg, hydrophobic amino acid residues (val, leu, ala, tyr, and phe), pro, and gly. |
2008-09-12 |
2023-08-12 |
Not clear |
| Marc A Gauthier, Harm-Anton Klo. Peptide/protein-polymer conjugates: synthetic strategies and design concepts. Chemical communications (Cambridge, England). issue 23. 2008-08-26. PMID:18535687. |
addressed topics include the residue- and/or site-specific modification of peptides/proteins at arg, asp, cys, gln, glu, gly, his, lys, met, phe, ser, thr, trp, tyr and val residues and methods for producing peptides/proteins containing non-canonical amino acids by peptide synthesis and protein engineering. |
2008-08-26 |
2023-08-12 |
Not clear |
| b' M Gredicak, A Koloni\\xc4\\x87, I Jeri\\xc4\\x8. Novel chloroenyne-modified amino acid derivatives. Amino acids. vol 35. issue 1. 2008-08-19. PMID:17619116.' |
chloroenyne moiety was attached at the n- or c-terminal amino acid (tyr, phe, val, gly, lys) position carrying different protecting groups. |
2008-08-19 |
2023-08-12 |
Not clear |
| M Katane, T Hanai, T Furuchi, M Sekine, H Homm. Hyperactive mutants of mouse D-aspartate oxidase: mutagenesis of the active site residue serine 308. Amino acids. vol 35. issue 1. 2008-08-19. PMID:18235994. |
recombinant mdaspo carrying a substitution of gly, ala, or tyr for ser-308 was generated, and fused to either his (his-mdaspo), or glutathione s-transferase, his, and s (ghs-mdaspo) at its n-terminus. |
2008-08-19 |
2023-08-12 |
mouse |
| M Zarrabi, H Naderi-Manes. The investigation of interactions of kappa-Hefutoxin1 with the voltage-gated potassium channels: a computational simulation. Proteins. vol 71. issue 3. 2008-08-15. PMID:18076029. |
lys 19, tyr 5, arg 6, trp 9, or arg 10 in the toxin and residues asp 402, his 404, thr 407,gly 401, and asp 386 in each subunit of the kv potassium channel are the key residues for the toxin-channel recognition. |
2008-08-15 |
2023-08-12 |
Not clear |
| Angela Bachi, Carolina Simó, Umberto Restuccia, Luc Guerrier, Frederic Fortis, Egisto Boschetti, Marco Masseroli, Pier Giorgio Righett. Performance of combinatorial peptide libraries in capturing the low-abundance proteome of red blood cells. 2. Behavior of resins containing individual amino acids. Analytical chemistry. vol 80. issue 10. 2008-08-11. PMID:18410134. |
sixteen different amino acids (arg, asn, asp, gln, glu, gly, his, ile, lys, phe, pro, ser, thr, trp, tyr, val) have been separately linked to chromatographic beads and used for studying the mechanism of binding of such baits to proteins, as represented by the cytoplasmic proteome of the human red blood cell (rbc). |
2008-08-11 |
2023-08-12 |
human |
| V L Bonfim, L A Ponce-Soto, D Martins de Souza, G H M F Souza, P A Baldasso, M N Eberlin, S Marangon. Structural and functional characterization of myotoxin, Cr-IV 1, a phospholipase A2 D49 from the venom of the snake Calloselasma rhodostoma. Biologicals : journal of the International Association of Biological Standardization. vol 36. issue 3. 2008-08-04. PMID:18249006. |
the sample was determined to have a molecular mass of 13,870.94 da maldi-tof by mass spectrometry, and the amino acid composition showed that cr-iv 1 presented a high content of lys, tyr, gly, pro, and 14 half-cys residues, typical of a basic pla(2). |
2008-08-04 |
2023-08-12 |
mouse |
| Yan-Lin Tao, Xun-Jia Cheng, Yong-Feng Fu, Hideo Tsukamoto, Eisaku Yoshihara, Hiroshi Tachiban. Modification of a human monoclonal antibody Fab fragment specific for Plasmodium falciparum 19-kDa C-terminal merozoite surface protein 1 by site-directed mutagenesis. Parasitology research. vol 103. issue 2. 2008-07-29. PMID:18446371. |
no effective replacements for tyr(92) and val(101) were found, but possible substitutions of ile(97) with gly, leu, glu, ala and ser, and of trp(107) with arg and ser were demonstrated. |
2008-07-29 |
2023-08-12 |
human |
| Norbert Stoppacher, Susanne Zeilinger, Markus Omann, Paul-Gerhard Lassahn, Andreas Roitinger, Rudolf Krska, Rainer Schuhmache. Characterisation of the peptaibiome of the biocontrol fungus Trichoderma atroviride by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. vol 22. issue 12. 2008-07-23. PMID:18470867. |
while the amino acid sequences of the novel peptaibiotics showed typical microheterogeneity and consisted of the amino acids leu/ile, aib, ser, val/iva, gly, ac-aib, tyr and phe, the mass increments at the c-termini of the peptides were not assignable to any residues described in the literature. |
2008-07-23 |
2023-08-12 |
Not clear |
| Sara Birtalan, Yingnan Zhang, Frederic A Fellouse, Lihua Shao, Gabriele Schaefer, Sachdev S Sidh. The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies. Journal of molecular biology. vol 377. issue 5. 2008-07-01. PMID:18336836. |
synthetic antibody libraries with restricted chemical diversity were used to explore the intrinsic contributions of four amino acids (tyr, ser, gly and arg) to the affinity and specificity of antigen recognition. |
2008-07-01 |
2023-08-12 |
Not clear |
| Sara Birtalan, Yingnan Zhang, Frederic A Fellouse, Lihua Shao, Gabriele Schaefer, Sachdev S Sidh. The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies. Journal of molecular biology. vol 377. issue 5. 2008-07-01. PMID:18336836. |
there was no correlation between nonspecific binding and the content of tyr, ser or gly in the antigen-binding site, and in fact, the most specific antibodies were those with the highest tyr content. |
2008-07-01 |
2023-08-12 |
Not clear |
| Sara Birtalan, Yingnan Zhang, Frederic A Fellouse, Lihua Shao, Gabriele Schaefer, Sachdev S Sidh. The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies. Journal of molecular biology. vol 377. issue 5. 2008-07-01. PMID:18336836. |
we combined tyr, ser and gly to generate highly specific synthetic antibodies with affinities in the subnanomolar range, showing that the high abundance of tyr, ser and gly in natural antibody germ line sequences reflects the intrinsic capacity of these residues to work together to mediate antigen recognition. |
2008-07-01 |
2023-08-12 |
Not clear |
| David B Dahl, Zach Bohannan, Qianxing Mo, Marina Vannucci, Jerry Tsa. Assessing side-chain perturbations of the protein backbone: a knowledge-based classification of residue Ramachandran space. Journal of molecular biology. vol 378. issue 3. 2008-06-13. PMID:18377931. |
there were seven general groups based on the clusters from the complete ramachandran data: nonpolar/beta-branched (ile and val), asx (asn and asp), long (met, gln, arg, glu, lys, and leu), aromatic (phe, tyr, his, and cys), small (ala and ser), bulky (thr and trp), and, lastly, the singletons of gly and pro. |
2008-06-13 |
2023-08-12 |
Not clear |
| Shouichi Higashi, Kaoru Miyazak. Identification of amino acid residues of the matrix metalloproteinase-2 essential for its selective inhibition by beta-amyloid precursor protein-derived inhibitor. The Journal of biological chemistry. vol 283. issue 15. 2008-05-28. PMID:18238779. |
studies of chimeric proteases, consisting of various parts of the mmp-2 catalytic domain and those of mmp-7 (matrilysin) or mmp-9 (gelatinase b), further revealed that ala(88) and gly(94) in the non-prime side and tyr(145) and thr(146) in the prime side of the substrate-binding cleft of mmp-2 contribute separately to the selective inhibition. |
2008-05-28 |
2023-08-12 |
Not clear |
| Orathai Jirapongsananuruk, Deborah Noack, Siribangon Boonchoo, Charin Thepthai, Kulkanya Chokephaibulkit, Nualanong Visitsunthorn, Pakit Vichyanond, Voravich Luangwedchakarn, Surachai Likasitwattanakul, Surapon Piboonpocanu. A novel mutation of the CYBB gene resulting in severe form of X-linked chronic granulomatous disease. Asian Pacific journal of allergy and immunology. vol 25. issue 4. 2008-05-21. PMID:18402299. |
as a result, 3 amino acids tyr 511, gly 512 and arg 513 were deleted and replaced by 2 amino acids, phe and gln. |
2008-05-21 |
2023-08-12 |
Not clear |
| Satoshi Maruta, Kaoru Yamaoka, Mari Yotsu-Yamashit. Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity. Toxicon : official journal of the International Society on Toxinology. vol 51. issue 3. 2008-05-13. PMID:18067939. |
we previously showed that asn-383 and thr-1569 residues of p-loop regions in domains i and iv, respectively, of the puffer fish, fugu pardialis, skeletal muscle na(v) (fna(v)1.4a), are anomalous to those of other species of ttx-sensitive na(+) channels, where the aromatic residues of phe or tyr, and gly are the counterparts [yotsu-yamashita, m., nishimori, k., nitanai, y., isemura, m., sugimoto, a., yasumoto, t., 2000. |
2008-05-13 |
2023-08-12 |
Not clear |
| Nicole M Very, Jeffrey D Kittilson, Sarah E Klein, Mark A Sherida. Somatostatin inhibits basal and growth hormone-stimulated hepatic insulin-like growth factor-I production. Molecular and cellular endocrinology. vol 281. issue 1-2. 2008-04-14. PMID:18006145. |
all ss isofoms tested, including the n-terminally extended form of ss-14-i, ss-28-i, and the [tyr(7), gly(10)]-substituted forms of ss, ss-14-ii, ss-25-ii and ss-28-ii, inhibited gh-stimulated igf-i mrna expression. |
2008-04-14 |
2023-08-12 |
Not clear |