| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Linliang Yu, Wei Lu, Yinan We. AcrB trimer stability and efflux activity, insight from mutagenesis studies. PloS one. vol 6. issue 12. 2012-07-20. PMID:22163011. |
we replaced p223 separately with five residues, including ala, val, tyr, asn, and gly, and found that acrb(p223g) was the least active. |
2012-07-20 |
2023-08-12 |
Not clear |
| Nannan Li, Liang Tan, Lin Yang, Ge Shi, Zhiping Wang, Zhi Lia. Purification, cDNA clone and recombinant expression of foot protein-3 from Mytilus coruscus. Protein and peptide letters. vol 18. issue 12. 2012-07-03. PMID:21787281. |
these precursors contain a putative signal peptide of 24 residues, a mature peptide sequence of 41-56 amino acids rich in tyr, gly, pro, and asn. |
2012-07-03 |
2023-08-12 |
Not clear |
| Swagata Chakraborty, P M Krishna Mohan, Ramakrishna V Hosu. Residual structure and dynamics in DMSO-d6 denatured dynein light chain protein. Biochimie. vol 94. issue 1. 2012-04-16. PMID:22079190. |
the hsqc spectrum shows the presence of two sets of peaks for the residues met 1, ser 2, arg 4, ala 11, met 17, thr 26, lys 44, tyr 50, asn 51, trp 54, his 55, val 58, gly 59, ser 64, tyr 65, his 68, phe 86, lys 87 indicating the presence of slow conformational transition in the heterogeneous ensemble. |
2012-04-16 |
2023-08-12 |
Not clear |
| Elżbieta Dąbrowska-Maś, Tomasz Frączyk, Tomasz Ruman, Karolina Radziszewska, Piotr Wilk, Joanna Cieśla, Zbigniew Zieliński, Agata Jurkiewicz, Barbara Gołos, Patrycja Wińska, Elżbieta Wałajtys-Rode, Andrzej Leś, Joanna Nizioł, Adam Jarmuła, Piotr Stefanowicz, Zbigniew Szewczuk, Wojciech Rod. Tyrosine nitration affects thymidylate synthase properties. Organic & biomolecular chemistry. vol 10. issue 2. 2012-04-10. PMID:22072032. |
nitration under the same conditions of model tripeptides of a general formula h(2)n-gly-x-gly-cooh (x = phe, tyr, trp, lys, arg, his, ser, thr, cys, gly), monitored by nmr spectroscopy, showed formation of nitro-species only for h-gly-tyr-gly-oh and h-gly-phe-gly-oh peptides, the chemical shifts for nitrated h-gly-tyr-gly-oh peptide being in a very good agreement with the strongest peak found in (15)n-(1)h hmbc spectrum of nitrated protein. |
2012-04-10 |
2023-08-12 |
mouse |
| Kevin A W Le. Molecular recognition by the EWS transcriptional activation domain. Advances in experimental medicine and biology. vol 725. 2012-04-10. PMID:22399321. |
the transcriptional activation domain (ead) of oncogenic ewing's sarcoma fusion proteins (efps) is an ≈280 residue idr with a biased composition restricted to ala, gly, gln, pro, ser, thr and tyr. |
2012-04-10 |
2023-08-12 |
Not clear |
| Marilda Rigobello-Masini, Jorge C Masin. Sequential injection chromatography for fluorimetric determination of intracellular amino acids in marine microalgae. Methods in molecular biology (Clifton, N.J.). vol 828. 2012-03-25. PMID:22125154. |
at a flow rate of 30 μl/s, a 25 mm long-column coupled to 5-mm guard column is capable to separate aspartic acid (asp), glutamic acid (glu), asparagine (asn), serine (ser), glycine (gly), threonine (thr), citrulline (ctr), arginine (arg), alanine (ala), tyrosine (tyr), phenylalanine (phe), ornithine (orn), and lysine (lys). |
2012-03-25 |
2023-08-12 |
Not clear |
| Tobias Härtel, Eva Eylert, Christian Schulz, Lothar Petruschka, Philipp Gierok, Stephanie Grubmüller, Michael Lalk, Wolfgang Eisenreich, Sven Hammerschmid. Characterization of central carbon metabolism of Streptococcus pneumoniae by isotopologue profiling. The Journal of biological chemistry. vol 287. issue 6. 2012-03-25. PMID:22167202. |
ala, ser, asp, and thr displayed high (13)c enrichments, whereas phe, tyr, and gly were only slightly labeled. |
2012-03-25 |
2023-08-12 |
Not clear |
| H Zhai, O Adeol. Apparent and standardized ileal digestibilities of amino acids for pigs fed corn- and soybean meal-based diets at varying crude protein levels. Journal of animal science. vol 89. issue 11. 2012-02-28. PMID:21724945. |
there were linear increases in aid of n, arg, gly, ile, lys, ser, thr, tyr, and val (p ≤ 0.05) as cp increased and linear decreases in sid of n and all aa measured in this study except lys, met, and pro (p ≤ 0.05). |
2012-02-28 |
2023-08-12 |
Not clear |
| Li Wang, Kai Zhang, Lianfeng Wu, Shengwu Liu, Honglian Zhang, Qiangjun Zhou, Liang Tong, Fei Sun, Zusen Fa. Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 2. 2012-02-21. PMID:22156497. |
the thr(189), gly(216), and gly(226) specificity triad in the s1 pocket of gzmh defines its preference for bulky, aromatic residues (tyr and phe) at the p1 position. |
2012-02-21 |
2023-08-12 |
human |
| Pooja Gupta, Susheel Duran. Aromatic interactions at atom-to-atom contact and just beyond: a case study of protein interactions of NAD⁺/NADP⁺. International journal of biological macromolecules. vol 49. issue 5. 2012-02-10. PMID:21903128. |
the order of enrichments over the contacted residues is tyr>cys>thr>his>asn>ser>met>ile>phe against nicotinamide-π(+) structure and asp>ile>thr>his>arg>tyr>gly>val against adenine-π structure, while the order over the non-contacted residues is trp>gly>his>asn>cys>met>tyr>ser>thr>phe against nicotinamide-π(+) structure and asn>thr>ser>gly>cys>his>val against adenine-π structure. |
2012-02-10 |
2023-08-12 |
Not clear |
| Pooja Gupta, Susheel Duran. Aromatic interactions at atom-to-atom contact and just beyond: a case study of protein interactions of NAD⁺/NADP⁺. International journal of biological macromolecules. vol 49. issue 5. 2012-02-10. PMID:21903128. |
neutral trp, his, tyr, and phe, but not cationic arg, are thus the non-contacted residues enriched specifically against nicotinamide-π(+) structure, while asn, gly, thr, ser, and cys are the non-contacted residues enriched generically against both the nicotinamide-π(+) and adenine-π aromatic structures. |
2012-02-10 |
2023-08-12 |
Not clear |
| b' Bart Vandormael, Danai-Dionysia Fourla, Alexandra Gramowski-Voss, Piotr Kosson, Dieter G Weiss, Olaf H-U Schr\\xc3\\xb6der, Andrzej Lipkowski, Zafiroula Georgoussi, Dirk Tourw\\xc3\\xa. Superpotent [Dmt\\xc2\\xb9] dermorphin tetrapeptides containing the 4-aminotetrahydro-2-benzazepin-3-one scaffold with mixed \\xce\\xbc/\\xce\\xb4 opioid receptor agonistic properties. Journal of medicinal chemistry. vol 54. issue 22. 2012-02-07. PMID:21978284.' |
novel dermorphin tetrapeptides are described in which tyr(1) is replaced by dmt(1), where d-ala(2) and gly(4) are n-methylated, and where phe(3)-gly(4) residue is substituted by the constrained aba(3)-gly(4) peptidomimetic. |
2012-02-07 |
2023-08-12 |
Not clear |
| Camilla Höglund, Nina Sneitz, Anna Radominska-Pandya, Liisa Laakonen, Moshe Fine. Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens. Steroids. vol 76. issue 13. 2012-02-03. PMID:21846474. |
in order to further understand and extend our earlier findings with phenylalanines 90 and 93 of ugt1a10, we have replaced each of them with gly, ala, val, leu, ile or tyr, and tested the activity of the resulting 12 mutants toward eight different substrates. |
2012-02-03 |
2023-08-12 |
human |
| Fred F Damberger, Barbara Christen, Daniel R Pérez, Simone Hornemann, Kurt Wüthric. Cellular prion protein conformation and function. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 42. 2011-12-30. PMID:21987789. |
here, it is shown that this local dynamic conformational polymorphism in mouse prp(c) is eliminated through exchange of tyr169 by ala or gly, but is preserved after exchange of tyr 169 with phe. |
2011-12-30 |
2023-08-12 |
mouse |
| Pradyot Koley, Michael G B Drew, Animesh Pramani. Salts responsive nanovesicles through pi-stacking induced self-assembly of backbone modified tripeptides. Journal of nanoscience and nanotechnology. vol 11. issue 8. 2011-12-19. PMID:22103076. |
a set of backbone modified peptides of general formula boc-xx-m-aba-yy-ome where m-aba is meta-aminobenzoic acid and xx and yy are natural amino acids such as phe, gly, pro, leu, ile, tyr and trp etc., are found to self-assemble into soft nanovesicular structures in methanol-water solution (9:1 by v/v). |
2011-12-19 |
2023-08-12 |
Not clear |
| Kimitsuna Watanabe, Shin-Ichi Yokobor. tRNA Modification and Genetic Code Variations in Animal Mitochondria. Journal of nucleic acids. vol 2011. 2011-11-10. PMID:22007289. |
they are uga (termination codon in the universal genetic code changes to trp codon in all animal mitochondria), aua (ile to met in most metazoan mitochondria), aaa (lys to asn in echinoderm and some platyhelminth mitochondria), aga/agg (arg to ser in most invertebrate, arg to gly in tunicate, and arg to termination in vertebrate mitochondria), and uaa (termination to tyr in a planaria and a nematode mitochondria, but conclusive evidence is lacking in this case). |
2011-11-10 |
2023-08-12 |
Not clear |
| Andy Chevigné, Aurélie Fischer, Julie Mathu, Manuel Counson, Nadia Beaupain, Jean-Marc Plesséria, Jean-Claude Schmit, Sabrina Dero. Selection of a CXCR4 antagonist from a human heavy chain CDR3-derived phage library. The FEBS journal. vol 278. issue 16. 2011-10-03. PMID:21651727. |
the hcdr3 length varied from 3 to 21 residues and displayed a biased amino acid content with a predominant proportion of tyr, gly, ser and asp. |
2011-10-03 |
2023-08-12 |
human |
| Hridoy R Bairagya, Bishnu P Mukhopadhyay, Asim K Ber. Conserved water mediated recognition and the dynamics of active site Cys 331 and Tyr 411 in hydrated structure of human IMPDH-II. Journal of molecular recognition : JMR. vol 24. issue 1. 2011-07-27. PMID:20135634. |
the stabilization of active site residues asn 303, gly 324, ser 329, cys 331, asp 364, and tyr 411 through variable h-bonding coordination from the conserved water molecular center seems interesting in the uninhibited hydrated form of human impdh-ii structures. |
2011-07-27 |
2023-08-12 |
human |
| Reinaldo Fraga Vidal, Claire Moulis, Pierre Escalier, Magali Remaud-Siméon, Pierre Monsa. Isolation of a gene from Leuconostoc citreum B/110-1-2 encoding a novel dextransucrase enzyme. Current microbiology. vol 62. issue 4. 2011-07-18. PMID:21229247. |
however, the variable region is longer than in other gtfs (by 100 amino acids) and two apy repeats (a 79 residue long motif with a high number of conserved glycine and aromatic residues, characterized by the presence of the three consecutive residues ala, pro, and tyr) were identified in the glucan binding domain. |
2011-07-18 |
2023-08-12 |
Not clear |
| Yunpeng Ye, Baogang Xu, Gregory V Nikiforovich, Sharon Bloch, Samuel Achilef. Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging. Bioorganic & medicinal chemistry letters. vol 21. issue 7. 2011-07-11. PMID:21349709. |
this was confirmed experimentally, which further showed that substitution of gly with pro, val and tyr in 1 remarkably hampered the α(v)β(3) binding. |
2011-07-11 |
2023-08-12 |
Not clear |