| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryousuke Ito, Yukari Masukawa, Chika Nakada, Kanako Amari, Chiaki Nakano, Tsutomu Hoshin. β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade. Organic & biomolecular chemistry. vol 12. issue 23. 2015-04-17. PMID:24695673. |
nine site-specific variants with gly, ala, val, leu, met, tyr, trp, his, and thr were constructed. |
2015-04-17 |
2023-08-13 |
Not clear |
| I A Malanicheva, D G Kozlov, T A Efimenko, V A Zenkova, G S Kastrukha, M I Reznikova, A M Korolev, L N Borshchevskaia, O D Tarasova, S P Sineokiĭ, O V Efremenkov. [New antibiotics produced by Bacillus subtilis strains]. Mikrobiologiia. vol 83. issue 4. 2015-04-17. PMID:25844455. |
strain ina 01086 produced also a cyclic polypeptide antibiotic containing asp, gly, leu, pro, tyr, thr, trp, and phe, while the antibiotic of strain ina 01085 contained, apart from these, two unidentified nonproteinaceous amino acids. |
2015-04-17 |
2023-08-13 |
Not clear |
| Zihao Chen, Tao Gao, Shuping Liang, Kexue Liu, Mingguo Zhou, Changjun Che. Molecular mechanism of resistance of Fusarium fujikuroi to benzimidazole fungicides. FEMS microbiology letters. vol 357. issue 1. 2015-04-16. PMID:24913566. |
in this study, we determined that although β1 tub and β2 -tubulin (β2 tub) in f. fujikuroi have high homology with β1 tub and β2 tub in f. verticillioides, mbc resistance in f. fujikuroi results from mutations in β2 tub [gag(glu)→gtg(val) at codon 198, ttc(phe)→tac(tyr) at codon 200, and ggc(gly)→ggt(gly) at codon 235] but not in β1 tub. |
2015-04-16 |
2023-08-13 |
Not clear |
| Arturo E Gonzalez-Iglesias, Patrick A Fletcher, José A Arias-Cristancho, Ruth Cristancho-Gordo, Cleyde V Helena, Richard Bertram, Joël Taba. Direct stimulatory effects of oxytocin in female rat gonadotrophs and somatotrophs in vitro: comparison with lactotrophs. Endocrinology. vol 156. issue 2. 2015-03-24. PMID:25406939. |
in these three cell types, the effects on hormone release and intracellular ca(2+) of both ot and [thr(4),gly(7)]oxytocin were abolished by the specific ot receptor antagonist desgly-nh2-d(ch2)5[d-tyr(2),thr(4)]ovt but not by the highly selective vasopressin v1a receptor antagonist, d(ch2)5[tyr(me)(2),dab(5)]avp. |
2015-03-24 |
2023-08-13 |
rat |
| Jong-Min Lim, Jayaraman Vikramathithan, Kwon Hwangbo, Joon-Woo Ahn, Youn-Il Park, Dong-Woog Choi, Won-Joong Jeon. Threonine 286 of fatty acid desaturase 7 is essential for ω-3 fatty acid desaturation in the green microalga Chlamydomonas reinhardtii. Frontiers in microbiology. vol 6. 2015-02-20. PMID:25699037. |
a ser substitution in position 286 was able to partially complement the phenotype of the ω-3 fatty acid deficiency, but other substitution variants, such as tyr, his, cys, and gly, failed to do so. |
2015-02-20 |
2023-08-13 |
Not clear |
| Hiroshi Ueno, Takahiro Yamaguchi, Saori Fukunaga, Yuki Okada, Yoshiaki Yano, Masaru Hoshino, Katsumi Matsuzak. Comparison between the aggregation of human and rodent amyloid β-proteins in GM1 ganglioside clusters. Biochemistry. vol 53. issue 48. 2015-02-13. PMID:25399921. |
rodent aβ (raβ) differs from human aβ (haβ) only in the three substitutions of arg to gly, tyr to phe, and his to arg at positions 5, 10, and 13, respectively. |
2015-02-13 |
2023-08-13 |
human |
| Xiaohui Liu, Ayami Matsushima, Miki Shimohigashi, Yasuyuki Shimohigash. A characteristic back support structure in the bisphenol A-binding pocket in the human nuclear receptor ERRγ. PloS one. vol 9. issue 6. 2015-02-12. PMID:24978476. |
when errγ-asn346 was replaced by the corresponding gly and tyr in errα and errβ, respectively, the binding affinity of bpa and even 4-hydroxytamxifen (4-oht) is much reduced. |
2015-02-12 |
2023-08-13 |
human |
| Alexandre Beautrait, Kevin R Michalski, Thomas S Lopez, Katelynn M Mannix, Devin J McDonald, Amber R Cutter, Christopher B Medina, Aaron M Hebert, Charnelle J Francis, Michel Bouvier, John J G Tesmer, Rachel Sterne-Mar. Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays. The Journal of biological chemistry. vol 289. issue 36. 2015-01-28. PMID:25049229. |
we suggest that a surface of grk2, including leu(4), val(7), leu(8), val(11), and ser(12), directly interacts with receptors, whereas residues such as asp(10), tyr(13), ala(16), met(17), gly(475), val(477), and ile(485) are more important for kinase domain closure and activation. |
2015-01-28 |
2023-08-13 |
Not clear |
| Dariusz Wasyl, Andrzej Hoszowski, Magdalena Zają. Prevalence and characterisation of quinolone resistance mechanisms in Salmonella spp. Veterinary microbiology. vol 171. issue 3-4. 2015-01-15. PMID:24613291. |
amplification and sequencing of quinolone resistance determining region of topoisomerases genes in 44 isolates identified multiple amino-acid substitutions in gyra at positions ser83 (n=22; → leu, → phe, → tyr), asp87 (n=22; → asn, → gly, → tyr) and parc (thr57ser, n=23; ala141ser, n=1). |
2015-01-15 |
2023-08-12 |
Not clear |
| M Yamakado, T Tanaka, K Nagao, Y Ishizaka, T Mitushima, M Tani, A Toda, E Toda, M Okada, H Miyano, H Yamamot. Plasma amino acid profile is associated with visceral fat accumulation in obese Japanese subjects. Clinical obesity. vol 2. issue 1-2. 2015-01-15. PMID:25586045. |
what this study adds • a specific formula incorporating six amino acid values (ala, gly, glu, trp, tyr and branched-chain amino acid) was developed for discrimination of subjects with high visceral fat area by multivariate logistic regression analyses. |
2015-01-15 |
2023-08-13 |
human |
| Shalon E Babbitt, Brian San Francisco, Deanna L Mendez, Gudrun S Lukat-Rodgers, Kenton R Rodgers, Eric C Bretsnyder, Robert G Kran. Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme attachment site, Cys-XX-Cys-His. The Journal of biological chemistry. vol 289. issue 42. 2014-12-22. PMID:25170082. |
substitutions of his-19 in cytochrome c to seven other residues (gly, ala, met, arg, lys, cys, and tyr) were used with various approaches to establish other roles played by his-19. |
2014-12-22 |
2023-08-13 |
human |
| Vladislav Victorovich Khrustalev, Eugene Victorovich Barkovsky, Tatyana Aleksandrovna Khrustalev. The influence of flanking secondary structures on amino Acid content and typical lengths of 3/10 helices. International journal of proteomics. vol 2014. 2014-11-05. PMID:25371821. |
the highest number of significant differences in amino acid usage was found between 3/10 helices containing bridges connecting two beta strands (they have increased phe, tyr, met, ile, leu, val, and his usages but decreased usages of asp, asn, gly, and pro) and those without 3/10 helices. |
2014-11-05 |
2023-08-13 |
Not clear |
| Sang-Mo Kang, Ramalingam Radhakrishnan, Young-Hyun You, Gil-Jae Joo, In-Jung Lee, Ko-Eun Lee, Jin-Ho Ki. Phosphate Solubilizing Bacillus megaterium mj1212 Regulates Endogenous Plant Carbohydrates and Amino Acids Contents to Promote Mustard Plant Growth. Indian journal of microbiology. vol 54. issue 4. 2014-10-16. PMID:25320441. |
in the biochemical analysis revealed that chlorophyll, sucrose, glucose, fructose and amino acids (asp, thr, ser, glu, gly, ala, cys, val, met, ilu, leu, tyr, phe, lys, his, arg and pro) were higher in b. megaterium mj1212 treated plants, when compared to their control. |
2014-10-16 |
2023-08-13 |
Not clear |
| Lei Zhang, Thor Bernt Melø, Heng Li, K Razi Naqvi, Chunhong Yan. The inter-monomer interface of the major light-harvesting chlorophyll a/b complexes of photosystem II (LHCII) influences the chlorophyll triplet distribution. Journal of plant physiology. vol 171. issue 5. 2014-09-24. PMID:24484957. |
we mutated the amino acid at site 123 located in this region to gly, pro, gln, thr and tyr, respectively, and recorded fluorescence excitation spectra, triplet-minus-singlet (tms) spectra and kinetics of carotenoid triplet decay for wild type and all the mutants. |
2014-09-24 |
2023-08-12 |
Not clear |
| Katsutaka Oishi, Saori Yamamoto, Nanako Itoh, Koyomi Miyazaki, Tadashi Nemoto, Yasukazu Nakakita, Hirotaka Kaned. Disruption of behavioral circadian rhythms induced by psychophysiological stress affects plasma free amino acid profiles without affecting peripheral clock gene expression in mice. Biochemical and biophysical research communications. vol 450. issue 1. 2014-09-21. PMID:24971530. |
nocturnal increases in branched-chain amino acids such as ile, leu, and val were further augmented in csd mice, while daytime increases in gly, ala, ser, thr, lys, arg, his, tyr, met, cys, glu, and asn were significantly attenuated. |
2014-09-21 |
2023-08-13 |
mouse |
| Vinod K Kannaujiya, Rajesh P Rastogi, Rajeshwar P Sinh. GC constituents and relative codon expressed amino acid composition in cyanobacterial phycobiliproteins. Gene. vol 546. issue 2. 2014-09-04. PMID:24933001. |
the coding selection pressure of amino acids such as ala, thr, tyr, asp, gly, ile, leu, asn, and ser in α and β subunits of pbps was more elaborated at g3c3 position. |
2014-09-04 |
2023-08-13 |
Not clear |
| Michael P Mullen, Fuller W Bazer, Guoyao Wu, Mervyn H Parr, Alexander C O Evans, Mark A Crowe, Michael G Diski. Effects of systemic progesterone during the early luteal phase on the availabilities of amino acids and glucose in the bovine uterine lumen. Reproduction, fertility, and development. vol 26. issue 2. 2014-09-02. PMID:23374643. |
total recoverable neutral (ser, gln, gly, thr, cit, β-ala, tau, ala, tyr, trp, met, val, phe, ile, leu, pro and cys), acidic (glu) and basic (his, arg, orn and lys) amino acids were greater (p<0.05) on day 13 than on day 7. |
2014-09-02 |
2023-08-12 |
cattle |
| Svetlana A Kholodar, Gregory Tombline, Juan Liu, Zhesen Tan, C Leigh Allen, Andrew M Gulick, Andrew S Murki. Alteration of the flexible loop in 1-deoxy-D-xylulose-5-phosphate reductoisomerase boosts enthalpy-driven inhibition by fosmidomycin. Biochemistry. vol 53. issue 21. 2014-07-21. PMID:24825256. |
we report that while mutation to ala or gly abolishes activity, mutation to phe and tyr only modestly impacts kcat and km. |
2014-07-21 |
2023-08-13 |
Not clear |
| Huaxi Yi, Xue Han, Yanyan Yang, Wenli Liu, Hui Liu, Yingchun Zhang, Kai Sun, Lanwei Zhang, Fang M. Effect of exogenous factors on bacteriocin production from Lactobacillus paracasei J23 by using a resting cell system. International journal of molecular sciences. vol 14. issue 12. 2014-07-15. PMID:24351821. |
cys and gly could stimulate the production of bacteriocin, while no stimulus effect was observed for glu, tyr and ala. glycerol and pyruvic acid increased bacteriocin production and the optimum concentrations were 1% and 30 g/l, respectively. |
2014-07-15 |
2023-08-12 |
Not clear |
| Hiroshi Kiyota, Masami Yokota Hirai, Masahiko Ikeuch. NblA1/A2-Dependent Homeostasis of Amino Acid Pools during Nitrogen Starvation in Synechocystis sp. PCC 6803. Metabolites. vol 4. issue 3. 2014-07-02. PMID:24983765. |
our study demonstrates that changes in the pool size of many amino acids during nitrogen starvation can be categorized as nbla1/a2-dependent (gln, glu, glutathione, gly, ile, leu, met, phe, pro, ser, thr, tyr and val) and nbla1/a2-independent (ala, asn, lys, and trp). |
2014-07-02 |
2023-08-13 |
Not clear |