| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Riley J Mangan, Lisa Stamper, Tomoo Ohashi, Joshua A Eudailey, Eden P Go, Frederick H Jaeger, Hannah L Itell, Brian E Watts, Genevieve G Fouda, Harold P Erickson, S Munir Alam, Heather Desaire, Sallie R Perma. Determinants of Tenascin-C and HIV-1 envelope binding and neutralization. Mucosal immunology. vol 12. issue 4. 2020-04-10. PMID:30976088. |
tenascin-c (tnc) is a large, hexameric extracellular matrix glycoprotein identified in breast milk and genital fluids that broadly neutralizes hiv-1 via interaction with the hiv-1 envelope (env) variable 3 (v3) loop. |
2020-04-10 |
2023-08-13 |
Not clear |
| Zhaoting Yang, Chengye Zhang, Ying Feng, Wenbo Qi, Yan Cui, Yanhua Xua. Tenascin-C is involved in promotion of cancer stemness via the Akt/HIF1ɑ axis in esophageal squamous cell carcinoma. Experimental and molecular pathology. vol 109. 2020-02-25. PMID:30904401. |
although tenascin-c (tnc), an extracellular matrix protein, has been shown to be widely expressed in stromal fibroblasts in various cancers, the role of its expression in esophageal squamous cell carcinoma (escc) cells remains unclear. |
2020-02-25 |
2023-08-13 |
Not clear |
| Hiroyuki Kato, Sergio Duarte, Mary G Miller, Ronald W Busuttil, Ana J Coit. Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 25. issue 2. 2020-02-14. PMID:30358115. |
tnc is an endogenous danger signal extracellular matrix molecule involved in various aspects of immunity and tissue injury. |
2020-02-14 |
2023-08-13 |
mouse |
| Hao Li, Xinlan Ge, Ke Pan, Minghao Sui, Huayong Cai, Chao Cui, Chonghui Li, Shichun L. The Predictive Role of Tenascin-C and Cellular Communication Network Factor 3 (CCN3) in Post Hepatectomy Liver Failure in a Rat Model and 50 Patients Following Partial Hepatectomy. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-12. PMID:31494663. |
background matricellular proteins of the extracellular matrix (ecm) include tenascin-c (tnc) and cellular communication network factor 3 (ccn3). |
2020-02-12 |
2023-08-13 |
rat |
| Larissa Cotrim-Sousa, Amanda Freire-Assis, Nicole Pezzi, Pedro Paranhos Tanaka, Ernna Hérida Oliveira, Geraldo Aleixo Passo. Adhesion between medullary thymic epithelial cells and thymocytes is regulated by miR-181b-5p and miR-30b. Molecular immunology. vol 114. 2020-01-21. PMID:31539668. |
analysis of broad mtec transcriptional expression showed that dicer kd led to the modulation of 114 mirnas and 422 mrnas, including those encoding cell adhesion or extracellular matrix proteins, such as lgals9, lgals3pb, tnc and cd47. |
2020-01-21 |
2023-08-13 |
Not clear |
| Jun Cai, Shaoxia Du, Hui Wang, Beibei Xin, Juan Wang, Wenyuan Shen, Wei Wei, Zhongkui Guo, Xiaohong She. Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer. Oncotarget. vol 8. issue 43. 2019-11-20. PMID:29088796. |
tenascin-c (tnc), a large extracellular matrix glycoprotein, has been reported to be associated with metastasis and poor prognosis in pancreatic cancer. |
2019-11-20 |
2023-08-13 |
Not clear |
| Arda Çetinkaya, Ekim Taşkıran, Tutku Soyer, Pelin Özlem Şimşek-Kiper, Gülen Eda Utine, Gökhan Tunçbilek, Koray Boduroğlu, Mehmet Alikaşifoğl. Dermal fibroblast transcriptome indicates contribution of WNT signaling pathways in the pathogenesis of Apert syndrome. The Turkish journal of pediatrics. vol 59. issue 6. 2019-11-20. PMID:30035392. |
col11a1, comp, cpxm2, itga8, mgf and tnc are differentially expressed genes that have go terms associated with extracellular matrix (ecm) organization, while frzb, sfrp2 and wnt2 are involved in wnt signaling pathway. |
2019-11-20 |
2023-08-13 |
human |
| Marcus May, Bernd Denecke, Timm Schroeder, Magdalena Götz, Andreas Faissne. Cell tracking Biology open. vol 7. issue 7. 2019-11-20. PMID:30045859. |
previously, we have shown that the glycoprotein of the extracellular matrix (ecm) tenascin-c (tnc) modulates the expression territories of the patterning genes nkx6.1 and nkx2.2 in the developing ventral spinal cord, tunes the responsiveness of neural stem/progenitor cells towards the cytokines fgf2 and egf and thereby promotes astrocyte maturation. |
2019-11-20 |
2023-08-13 |
Not clear |
| Hidenori Suzuki, Masashi Fujimoto, Fumihiro Kawakita, Lei Liu, Fumi Nakano, Hirofumi Nishikawa, Takeshi Okada, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Masato Shib. Toll-Like Receptor 4 and Tenascin-C Signaling in Cerebral Vasospasm and Brain Injuries After Subarachnoid Hemorrhage. Acta neurochirurgica. Supplement. vol 127. 2019-10-28. PMID:31407069. |
tlr4 activation induces tenascin-c (tnc), a representative of matricellular proteins that are a class of inducible, nonstructural, secreted, and multifunctional extracellular matrix glycoproteins. |
2019-10-28 |
2023-08-13 |
Not clear |
| Ayasa Nakamura, Jyoji Morise, Keiko Yabuno-Nakagawa, Yuki Hashimoto, Hiromu Takematsu, Shogo Ok. Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1. PloS one. vol 14. issue 1. 2019-09-30. PMID:30629639. |
here, we showed that one of the major hnk-1 carrier proteins in the embryonic brain is tenascin-c (tnc), an extracellular matrix protein that regulates neurite outgrowth by interacting with the gpi-anchored protein contactin-1 (cntn). |
2019-09-30 |
2023-08-13 |
human |
| Shuangqin Chen, Haiyan Fu, Songzhao Wu, Wenjuan Zhu, Jinlin Liao, Xue Hong, Jinhua Miao, Congwei Luo, Yongping Wang, Fan Fan Hou, Lili Zhou, Youhua Li. Tenascin-C protects against acute kidney injury by recruiting Wnt ligands. Kidney international. vol 95. issue 1. 2019-08-19. PMID:30409456. |
we have previously shown that the extracellular matrix glycoprotein tenascin-c (tnc) is induced in fibrotic kidneys. |
2019-08-19 |
2023-08-13 |
mouse |
| Agata Radwanska, Dominique Grall, Sébastien Schaub, Stéphanie Beghelli-de la Forest Divonne, Delphine Ciais, Samah Rekima, Tristan Rupp, Anne Sudaka, Gertraud Orend, Ellen Van Obberghen-Schillin. Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells. Scientific reports. vol 7. issue 1. 2019-06-27. PMID:28986537. |
cellular fibronectin (fn) and tenascin-c (tnc) are prominent development- and disease-associated matrix components with pro- and anti-adhesive activity, respectively. |
2019-06-27 |
2023-08-13 |
Not clear |
| Agata Radwanska, Dominique Grall, Sébastien Schaub, Stéphanie Beghelli-de la Forest Divonne, Delphine Ciais, Samah Rekima, Tristan Rupp, Anne Sudaka, Gertraud Orend, Ellen Van Obberghen-Schillin. Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells. Scientific reports. vol 7. issue 1. 2019-06-27. PMID:28986537. |
this effect counteracts the potent anti-adhesive activity of tnc and leads to the assembly of a dense highly-branched subendothelial matrix that enhances tubulogenic activity. |
2019-06-27 |
2023-08-13 |
Not clear |
| S Becerril, A Rodríguez, V Catalán, L Méndez-Giménez, B Ramírez, N Sáinz, M Llorente, X Unamuno, J Gómez-Ambrosi, G Frühbec. Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C. International journal of obesity (2005). vol 42. issue 8. 2019-06-24. PMID:29449623. |
targeted disruption of the inos gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin c. obesity is related to a dynamic extracellular matrix (ecm) remodeling, which involves the synthesis and degradation of different proteins, such as tenascin c (tnc) in the adipose tissue (at). |
2019-06-24 |
2023-08-13 |
mouse |
| Wen Gao, Jian Li, Huanchun Ni, Haiming Shi, Zhiyong Qi, Shouguo Zhu, Chuanming Hao, Qionghong Xie, Xinping Luo, Kun Xi. Tenascin C: A Potential Biomarker for Predicting the Severity of Coronary Atherosclerosis. Journal of atherosclerosis and thrombosis. vol 26. issue 1. 2019-06-10. PMID:29769455. |
tenascin c (tnc) is an extracellular matrix glycoprotein that is found in low concentrations in normal tissues and is enhanced by a range of cardiovascular pathologies. |
2019-06-10 |
2023-08-13 |
Not clear |
| Shani Samuel, Raja Elina Ahmad, Thamil Selvee Ramasamy, Puvanan Karunanithi, Sangeetha Vasudevaraj Naveen, Tunku Kamaru. Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate. Platelets. vol 30. issue 1. 2019-03-15. PMID:29090639. |
results showed that the cells cultured in the presence of prc for 24 days maintained a chondrocytic phenotype and demonstrated minimal upregulation of cartilaginous extracellular matrix (ecm) marker genes (sox9, tnc, col2, acan, comp) and reduced expression of chondrocyte hypertrophy genes (col x, runx2) compared to the standard chondrogenic medium (p < 0.05). |
2019-03-15 |
2023-08-13 |
human |
| Juan Li, Yiqiong Liu, Yiming Wang, Wen X. Expression of tenascin-C in a rat vocal fold injury model and its regulation of fibroblasts. The Laryngoscope. vol 128. issue 9. 2019-02-08. PMID:29572861. |
tenascin-c (tnc) is an extracellular matrix (ecm) glycoprotein that plays a vital role in wound healing and fibrotic disease. |
2019-02-08 |
2023-08-13 |
rat |
| Naohide Ageyama, Hiroyuki Kurosawa, Ousuke Fujimoto, Tomoya Uehara, Michiaki Hiroe, Yasushi Arano, Toshimichi Yoshida, Yasuhiro Yasutomi, Kyoko Imanaka-Yoshid. Successful Inflammation Imaging of Non-Human Primate Hearts Using an Antibody Specific for Tenascin-C. International heart journal. vol 60. issue 1. 2019-02-07. PMID:30464121. |
tenascin-c (tnc) is an extracellular matrix molecule not normally expressed, but it is strongly upregulated when associated with active inflammation. |
2019-02-07 |
2023-08-13 |
rat |
| Chaoyong Shen, Chengshi Wang, Yuan Yin, Huijiao Chen, Xiaonan Yin, Zhaolun Cai, Zhixin Chen, Bo Zhang, Zongguang Zho. Tenascin-C expression is significantly associated with the progression and prognosis in gastric GISTs. Medicine. vol 98. issue 2. 2019-01-22. PMID:30633201. |
tenascin-c (tnc), an extracellular matrix glycoprotein, has been implicated in progression of various types of cancer. |
2019-01-22 |
2023-08-13 |
Not clear |
| Zhaoting Yang, Chengye Zhang, Wenbo Qi, Chunai Cui, Yan Cui, Yanhua Xua. Tenascin-C as a prognostic determinant of colorectal cancer through induction of epithelial-to-mesenchymal transition and proliferation. Experimental and molecular pathology. vol 105. issue 2. 2019-01-17. PMID:30170017. |
although tenascin-c (tnc) as an extracellular matrix protein involved in various cancers, the mechanisms by which tnc leads to decreased survival time remain to be clarified in crc. |
2019-01-17 |
2023-08-13 |
Not clear |