| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sama Abdulmalik, Daisy Ramos, Swetha Rudraiah, Yeshavanth Kumar Banasavadi-Siddegowda, Sangamesh G Kumba. The glucagon-like peptide 1 receptor agonist Exendin-4 induces tenogenesis in human mesenchymal stem cells. Differentiation; research in biological diversity. vol 120. 2021-08-23. PMID:34062407. |
collectively, the levels of tendon-related transcription factors (mkx and scx) and extracellular matrix (col-i, dcn, bgn, and tnc) genes and proteins were elevated compared to media without ex-4 and other controls including insulin and igf-1 treatments. |
2021-08-23 |
2023-08-13 |
human |
| Yuichiro Shiomi, Miki Yokokawa, Hiroyasu Uzui, Kaori Hisazaki, Tetsuji Morishita, Kentaro Ishida, Yoshitomo Fukuoka, Kanae Hasegawa, Hiroyuki Ikeda, Naoto Tama, Kenichi Kaseno, Shinsuke Miyazaki, Naoki Amaya, Hiroshi Tad. Serum tenascin-C levels in atrium predict atrial structural remodeling processes in patients with atrial fibrillation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. vol 59. issue 2. 2021-08-18. PMID:31820271. |
serum concentrations of tenascin-c (tnc), an extracellular matrix glycoprotein, and of high-sensitivity c-reactive protein (crp) might serve as a marker of remodeling and progressive inflammation of the aorta and in myocardial diseases. |
2021-08-18 |
2023-08-13 |
Not clear |
| Saori Yonebayashi, Kazuko Tajiri, Mari Hara, Hiromitsu Saito, Noboru Suzuki, Satoshi Sakai, Taizo Kimura, Akira Sato, Akiyo Sekimoto, Satoshi Fujita, Ryuji Okamoto, Robert J Schwartz, Toshimichi Yoshida, Kyoko Imanaka-Yoshid. Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C. Frontiers in immunology. vol 12. 2021-06-25. PMID:33763067. |
generation of transgenic mice that conditionally overexpress tenascin-c. tenascin-c (tnc) is an extracellular matrix glycoprotein that is expressed during embryogenesis. |
2021-06-25 |
2023-08-13 |
mouse |
| Dunja Bijelić, Marija Adžić, Mina Perić, Igor Jakovčevski, Eckart Förster, Melitta Schachner, Pavle R Andju. Different Functions of Recombinantly Expressed Domains of Tenascin-C in Glial Scar Formation. Frontiers in immunology. vol 11. 2021-06-24. PMID:33679718. |
extracellular matrix glycoprotein tenascin-c (tnc) is highly expressed in vertebrates during embryonic development and thereafter transiently in tissue niches undergoing extensive remodeling during regeneration after injury. |
2021-06-24 |
2023-08-13 |
mouse |
| Dunja Bijelić, Marija Adžić, Mina Perić, Igor Jakovčevski, Eckart Förster, Melitta Schachner, Pavle R Andju. Different Functions of Recombinantly Expressed Domains of Tenascin-C in Glial Scar Formation. Frontiers in immunology. vol 11. 2021-06-24. PMID:33679718. |
upon central nervous system injury, tnc is upregulated and secreted into the extracellular matrix mainly by astrocytes. |
2021-06-24 |
2023-08-13 |
mouse |
| Mariska T Meijer, Alex F de Vos, Brendon P Scicluna, Joris J Roelofs, Chérine Abou Fayçal, Gertraud Orend, Fabrice Uhel, Tom van der Pol. Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Frontiers in immunology. vol 12. 2021-06-23. PMID:33776992. |
tenascin-c deficiency is associated with reduced bacterial outgrowth during tenascin c (tnc) is an extracellular matrix glycoprotein that recently emerged as an immunomodulator. |
2021-06-23 |
2023-08-13 |
Not clear |
| Masahiro Hasegawa, Toshimichi Yoshida, Akihiro Sud. Tenascin-C in Osteoarthritis and Rheumatoid Arthritis. Frontiers in immunology. vol 11. 2021-06-18. PMID:33101302. |
tenascin-c (tnc) is a large multimodular glycoprotein of the extracellular matrix that consists of four distinct domains. |
2021-06-18 |
2023-08-13 |
Not clear |
| Masahiro Hasegawa, Toshimichi Yoshida, Akihiro Sud. Tenascin-C in Osteoarthritis and Rheumatoid Arthritis. Frontiers in immunology. vol 11. 2021-06-18. PMID:33101302. |
for instance, some tnc fragments including the fibrinogen-like globe domain might function as endogenous inducers of synovitis and cartilage matrix degradation through binding with toll-like receptor-4, while full-length tnc promotes cartilage repair and prevents the development of oa without exacerbating synovitis. |
2021-06-18 |
2023-08-13 |
Not clear |
| Kyoko Imanaka-Yoshid. Tenascin-C in Heart Diseases-The Role of Inflammation. International journal of molecular sciences. vol 22. issue 11. 2021-06-18. PMID:34072423. |
tenascin-c (tnc) is a large extracellular matrix (ecm) glycoprotein and an original member of the matricellular protein family. |
2021-06-18 |
2023-08-13 |
mouse |
| Xiang Cheng, Fen Li, Zezhang Ta. Tenascin-C promotes epithelial-to-mesenchymal transition and the mTOR signaling pathway in nasopharyngeal carcinoma. Oncology letters. vol 22. issue 1. 2021-06-12. PMID:34113398. |
tenascin-c (tnc) is a large extracellular matrix glycoprotein that promotes cell adhesion and tissue remodeling, and is involved in the transduction of cellular signaling pathways. |
2021-06-12 |
2023-08-13 |
Not clear |
| Xiaohong Mao, Xin Zhang, Xiaowei Zheng, Yongwu Chen, Zixue Xuan, Ping Huan. Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway. Journal of natural medicines. vol 75. issue 3. 2021-06-09. PMID:33713277. |
in addition, we also found that curcumin inhibited the extracellular matrix (ecm)-receptor interaction pathway via the downregulation of the following genes: gp1bb, col9a3, comp, agrn, itgb4, lama5, col2a1, itgb6, itga1, and tnc. |
2021-06-09 |
2023-08-13 |
Not clear |
| Susanne Wiemann, Aisha Yousf, Stephanie C Joachim, Carolin Peters, Ana M Mueller-Buehl, Natalie Wagner, Jacqueline Reinhar. Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction. Frontiers in neuroscience. vol 15. 2021-06-08. PMID:34093110. |
recently, evidence accumulated suggesting that the extracellular matrix (ecm) glycoprotein tenascin-c (tnc) plays a key role in ischemic degeneration. |
2021-06-08 |
2023-08-13 |
Not clear |
| Daniel Manrique-Castano, Egor Dzyubenko, Mina Borbor, Paraskevi Vasileiadou, Christoph Kleinschnitz, Lars Roll, Andreas Faissner, Dirk M Herman. Tenascin-C preserves microglia surveillance and restricts leukocyte and, more specifically, T cell infiltration of the ischemic brain. Brain, behavior, and immunity. vol 91. 2021-05-27. PMID:33122023. |
as an endogenous activator of toll-like receptor-4 (tlr4), the extracellular matrix glycoprotein tenascin-c (tnc) regulates chemotaxis, phagocytosis and proinflammatory cytokine production in microglia. |
2021-05-27 |
2023-08-13 |
Not clear |
| Yiwei Xu, Jing Zhou, Cuicui Liu, Sheng Zhang, Fenglin Gao, Wenjing Guo, Xiumin Sun, Chi Zhang, Heying Li, Zilong Rao, Shuai Qiu, Qingtang Zhu, Xiaolin Liu, Xiaodong Guo, Zengwu Shao, Ying Bai, Xiao Zhang, Daping Qua. Understanding the role of tissue-specific decellularized spinal cord matrix hydrogel for neural stem/progenitor cell microenvironment reconstruction and spinal cord injury. Biomaterials. vol 268. 2021-05-24. PMID:33341040. |
proteomics analyses suggest that dscm specific extracellular matrix proteins, such as the tenascin family (tnc) and some soluble growth factor (fgf2) may contribute to these regulations. |
2021-05-24 |
2023-08-13 |
Not clear |
| Milena Tucić, Vera Stamenković, Pavle Andju. The Extracellular Matrix Glycoprotein Tenascin C and Adult Neurogenesis. Frontiers in cell and developmental biology. vol 9. 2021-05-18. PMID:33996833. |
tenascin c (tnc) is a glycoprotein highly expressed in the extracellular matrix (ecm) during development and in the adult central nervous system (cns) in regions of active neurogenesis, where neuron development is a tightly regulated process orchestrated by extracellular matrix components. |
2021-05-18 |
2023-08-13 |
Not clear |
| Mariska T Meijer, Fabrice Uhel, Olaf L Cremer, Marcus J Schultz, Tom van der Pol. Tenascin C Plasma Levels in Critically Ill Patients with or Without Sepsis: A Multicenter Observational Study. Shock (Augusta, Ga.). vol 54. issue 1. 2021-05-14. PMID:31764620. |
tenascin c (tnc) is an extracellular matrix protein able to modulate the immune response. |
2021-05-14 |
2023-08-13 |
human |
| Young Eun Choi, Min Ji Song, Mari Hara, Kyoko Imanaka-Yoshida, Dong Hun Lee, Jin Ho Chung, Seung-Taek Le. Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. International journal of molecular sciences. vol 21. issue 22. 2021-03-04. PMID:33217999. |
tenascin c (tnc) is an element of the extracellular matrix (ecm) of various tissues, including the skin, and is involved in modulating ecm integrity and cell physiology. |
2021-03-04 |
2023-08-13 |
Not clear |
| Satoru Furuhashi, Takanori Sakaguchi, Tomohiro Murakami, Mayu Fukushima, Yoshifumi Morita, Koji Ikegami, Hirotoshi Kikuchi, Mitsutoshi Setou, Hiroya Takeuch. Tenascin C in the Tumor-Nerve Microenvironment Enhances Perineural Invasion and Correlates With Locoregional Recurrence in Pancreatic Ductal Adenocarcinoma. Pancreas. vol 49. issue 3. 2021-02-25. PMID:32132519. |
tenascin c (tnc), an extracellular matrix glycoprotein, modulates tumor progression. |
2021-02-25 |
2023-08-13 |
Not clear |
| Sayda Dhaouadi, Devadarssen Murdamoothoo, Asma Tounsi, William Erne, Rahma Benabderrazek, Zakaria Benlasfar, Lotfi Hendaoui, Ruth Chiquet-Ehrismann, Samir Boubaker, Gertraud Orend, Ismaïl Hendaoui, Balkiss Bouhaouala-Zaha. Generation and characterization of dromedary Tenascin-C and Tenascin-W specific antibodies. Biochemical and biophysical research communications. vol 530. issue 2. 2021-02-25. PMID:32593416. |
we show that immune sera from immunized dromedaries are able to specifically bind native tnc and tnw by elisa and also to detect tnc and tnw in matrix tracks of mammary tumors by immunostaining. |
2021-02-25 |
2023-08-13 |
Not clear |
| Reza Mirzaei, Susobhan Sarkar, Lauren Dzikowski, Khalil S Rawji, Lubaba Khan, Andreas Faissner, Pinaki Bose, V Wee Yon. Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity. Oncoimmunology. vol 7. issue 10. 2021-01-12. PMID:30288344. |
we present evidence that btics produce the extracellular matrix protein tenascin-c (tnc) to inhibit t cell activity in live co-culture. |
2021-01-12 |
2023-08-13 |
human |