| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Egor Dzyubenko, Daniel Manrique-Castano, Matthias Pillath-Eilers, Paraskevi Vasileiadou, Jacqueline Reinhard, Andreas Faissner, Dirk M Herman. Tenascin-C restricts reactive astrogliosis in the ischemic brain. Matrix biology : journal of the International Society for Matrix Biology. 2022-04-17. PMID:35430380. |
we explored the role of tenascin-c (tnc), an extracellular matrix component involved in wound healing and remodeling of injured tissues, in mice exposed to ischemic stroke induced by transient intraluminal middle cerebral artery occlusion. |
2022-04-17 |
2023-08-13 |
mouse |
| Elena Schaberg, Magdalena Götz, Andreas Faissne. The extracellular matrix molecule tenascin-C modulates cell cycle progression and motility of adult neural stem/progenitor cells from the subependymal zone. Cellular and molecular life sciences : CMLS. vol 79. issue 5. 2022-04-17. PMID:35430697. |
the stem cell niche of the sez provides a privileged environment composed of a specialized extracellular matrix (ecm) that comprises the glycoproteins tenascin-c (tnc) and laminin-1 (ln1). |
2022-04-17 |
2023-08-13 |
Not clear |
| Ilnaz Rahimmanesh, Razieh Fatehi, Hossein Khanahma. Identification of Significant Genes and Pathways Associated with Tenascin-C in Cancer Progression by Bioinformatics Analysis. Advanced biomedical research. vol 11. 2022-04-07. PMID:35386538. |
tenascin-c (tnc) is a large glycoprotein of the extracellular matrix which associated with poor clinical outcomes in several malignancies. |
2022-04-07 |
2023-08-13 |
Not clear |
| Chao Liu, Zi-Qing Gao, Juan Li, Qi Zho. Identification of novel therapeutic targets for Fuchs' endothelial corneal dystrophy based on gene bioinformatics analysis. PloS one. vol 17. issue 3. 2022-03-03. PMID:35239706. |
both collagen-containing extracellular matrix and extracellular matrix hit to anxa1, vcan, gpc3, tnc, igfbp7, matn3, and sparcl1 genes in the go cellular components. |
2022-03-03 |
2023-08-13 |
Not clear |
| Thomas Loustau, Chérine Abou-Faycal, William Erne, Pia Abel Zur Wiesch, Ayoub Ksouri, Thomas Imhof, Matthias Mörgelin, Chengbei Li, Malaurie Mathieu, Nathalie Salomé, Gerard Crémel, Sayda Dhaouadi, Balkiss Bouhaouala-Zahar, Manuel Koch, Gertraud Oren. Modulating tenascin-C functions by targeting the MAtrix REgulating MOtif, "MAREMO". Matrix biology : journal of the International Society for Matrix Biology. 2022-03-01. PMID:35227929. |
the extracellular matrix molecule tenascin-c (tnc) promotes cancer and chronic inflammation by multiple mechanisms. |
2022-03-01 |
2023-08-13 |
Not clear |
| Thomas Loustau, Chérine Abou-Faycal, William Erne, Pia Abel Zur Wiesch, Ayoub Ksouri, Thomas Imhof, Matthias Mörgelin, Chengbei Li, Malaurie Mathieu, Nathalie Salomé, Gerard Crémel, Sayda Dhaouadi, Balkiss Bouhaouala-Zahar, Manuel Koch, Gertraud Oren. Modulating tenascin-C functions by targeting the MAtrix REgulating MOtif, "MAREMO". Matrix biology : journal of the International Society for Matrix Biology. 2022-03-01. PMID:35227929. |
we further demonstrated that the m-motif mimetic peptides blocked several functions of tnc, such as binding of tnc to fn, cell rounding on a mixed fn/tnc substratum, fn matrix expression and subsequent assembly, tnc-induced signaling and gene expression, tnc chemokine binding and dendritic cell retention, thus providing novel opportunities to inhibit tnc actions. |
2022-03-01 |
2023-08-13 |
Not clear |
| Minhua Yan, Shaojun Liu, Min Zhang, Lingyun Lai, Qionghong Xie, Chuan-Ming Ha. Mesangial Cell-Derived Tenascin-C Contributes to Mesangial Cell Proliferation and Matrix Protein Production in IgA Nephropathy. Nephrology (Carlton, Vic.). 2022-02-25. PMID:35213087. |
tenascin-c (tnc), a non-structural extracellular matrix glycoprotein, is transiently expressed during development or after injury, playing an important role in injury and repair process. |
2022-02-25 |
2023-08-13 |
Not clear |
| M Bohlouli, K Halli, T Yin, N Gengler, S Köni. Genome-wide associations for heat stress response suggest potential candidate genes underlying milk fatty acid composition in dairy cattle. Journal of dairy science. 2022-01-31. PMID:35094857. |
genetic correlations between the same fa under tnc and hsc were smallest in the first lactation stage and ranged from 0.20 for pufa to 0.87 for sfa when modeling with the a matrix, and from 0.35 for ufa to 0.86 for sfa when modeling with the g matrix. |
2022-01-31 |
2023-08-13 |
cattle |
| Yang Li, Min Li, Caijie Qu, Yongxi Li, Zhanli Tang, Zhike Zhou, Zengzhao Yu, Xu Wang, Linlin Xin, Tongxin Sh. The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082796. |
for example, il17ra is involved in il-17 signal transduction, timp2 and mmp14 activate extracellular matrix metalloproteinases, and tnc, itgb2, and itga4 interact with cell surface integrins. |
2022-01-27 |
2023-08-13 |
Not clear |
| Chimwemwe Mwase, Thien-Khoi N Phung, Michael J O'Sullivan, Jennifer A Mitchel, Margherita De Marzio, Ayşe Kılıç, Scott T Weiss, Jeffrey J Fredberg, Jin-Ah Par. Mechanical Compression of Human Airway Epithelial Cells Induces Release of Extracellular Vesicles Containing Tenascin C. Cells. vol 11. issue 2. 2022-01-21. PMID:35053372. |
here, we examine compression-induced expression and secretion of the extracellular matrix protein tenascin c (tnc) from well-differentiated primary human bronchial epithelial (hbe) cells grown in an air-liquid interface culture. |
2022-01-21 |
2023-08-13 |
human |
| Meera Saxena, Mizue Hisano, Melanie Neutzner, Maren Diepenbruck, Robert Ivanek, Kirti Sharma, Ravi K R Kalathur, Thomas R Bürglin, Salvatore Risoli, Gerhard Christofor. The long non-coding RNA ET-20 mediates EMT by impairing desmosomes in breast cancer cells. Journal of cell science. vol 134. issue 21. 2021-12-02. PMID:34633031. |
tnc is an extracellular matrix protein that is critical for emt and metastasis formation. |
2021-12-02 |
2023-08-13 |
human |
| Rui Peng, Di Li, Yan L. Relationships Between Circulating Tenascin-C Levels and Gonadal Hormones in Male Patients with Depressive Disorder: A Retrospective, Cross-Sectional Study. Laboratory medicine. 2021-11-18. PMID:34791329. |
tenascin-c (tnc) is an extracellular matrix glycoprotein closely associated with the progression of psychiatric disorders. |
2021-11-18 |
2023-08-13 |
Not clear |
| Sandrine Gremlich, Tiziana P Cremona, Eveline Yao, Farah Chabenet, Kleanthis Fytianos, Matthias Roth-Kleiner, Johannes C Schittn. Tenascin-C: Friend or Foe in Lung Aging? Frontiers in physiology. vol 12. 2021-11-17. PMID:34777012. |
tenascin-c (tnc) is a large extracellular matrix (ecm) protein with paracrine and autocrine regulatory functions on cell migration, proliferation and differentiation. |
2021-11-17 |
2023-08-13 |
mouse |
| Mariska T Meijer, Alex F de Vos, Hessel Peters Sengers, Brendon P Scicluna, Joris J Roelofs, Chérine Abou Fayçal, Fabrice Uhel, Gertraud Orend, Tom van der Pol. Tenascin C Has a Modest Protective Effect on Acute Lung Pathology during Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia in Mice. Microbiology spectrum. vol 9. issue 1. 2021-11-09. PMID:34319124. |
tenascin c (tnc) is an extracellular matrix protein with immunomodulatory properties that plays a major role during tissue injury and repair. |
2021-11-09 |
2023-08-13 |
mouse |
| Ouafa Hamza, Attila Kiss, Anne-Margarethe Kramer, Sandra Trojanek, Dietmar Abraham, Eylem Acar, Felix Nagel, Verena Eva Tretter, Melitta Kitzwögerer, Bruno K Podesse. Tenascin C promotes valvular remodeling in two large animal models of ischemic mitral regurgitation. Basic research in cardiology. vol 115. issue 6. 2021-10-18. PMID:33258993. |
tenascin c (tnc), an extracellular matrix glycoprotein involved in cardiovascular remodeling and fibrosis, was also identified in inducing epithelial-to-mesenchymal transition. |
2021-10-18 |
2023-08-13 |
Not clear |
| Motomichi Fujita, Hideo Suzuki, Fumio Fuka. Involvement of integrin-activating peptides derived from tenascin-C in colon cancer progression. World journal of gastrointestinal oncology. vol 13. issue 9. 2021-10-08. PMID:34616507. |
tenascin-c (tnc) is an adhesion modulatory protein present in the extracellular matrix that is highly expressed in several malignancies, including colon cancer. |
2021-10-08 |
2023-08-13 |
Not clear |
| Sayda Dhaouadi, Rahma Ben Abderrazek, Thomas Loustau, Chérine Abou-Faycal, Ayoub Ksouri, William Erne, Devadarssen Murdamoothoo, Matthias Mörgelin, Andreas Kungl, Alain Jung, Sonia Ledrappier, Zakaria Benlasfar, Sandrine Bichet, Ruth Chiquet-Ehrismann, Ismaïl Hendaoui, Gertraud Orend, Balkiss Bouhaouala-Zaha. Novel Human Tenascin-C Function-Blocking Camel Single Domain Nanobodies. Frontiers in immunology. vol 12. 2021-09-21. PMID:33790905. |
the extracellular matrix (ecm) molecule tenascin-c (tnc) is well-known to promote tumor progression by multiple mechanisms. |
2021-09-21 |
2023-08-13 |
human |
| Caroline Spenlé, Thomas Loustau, Hélène Burckel, Gilles Riegel, Chérine Abou Faycal, Chengbei Li, Alev Yilmaz, Luciana Petti, Fanny Steinbach, Constance Ahowesso, Camille Jost, Nicodème Paul, Raphael Carapito, Georges Noël, Fabienne Anjuère, Nathalie Salomé, Gertraud Oren. Impact of Tenascin-C on Radiotherapy in a Novel Syngeneic Oral Squamous Cell Carcinoma Model With Spontaneous Dissemination to the Lymph Nodes. Frontiers in immunology. vol 12. 2021-09-20. PMID:34290694. |
by investigating expression of the extracellular matrix molecule tenascin-c (tnc), an indicator of an immune suppressive tme, we observed high local tnc expression and til infiltration in the irradiated tumors. |
2021-09-20 |
2023-08-13 |
human |
| Di Zhang, Zhi Liu, Qianqian Liu, Honghai Lan, Jinjin Peng, Xiaowei Liu, Wei Li. Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating TLR4 and TGF-β Signaling Pathways. Inflammation. 2021-08-31. PMID:34463846. |
in vivo, tnc mostly located at the extracellular matrix of thickened alveolar septum, especially at sites of injury, together with the increasing of tlr4, nf-κb p65, tgf-β1, and α-sma. |
2021-08-31 |
2023-08-13 |
mouse |
| Jing Song, Anja Schwenzer, Alicia Wong, Sara Turcinov, Cliff Rims, Lorena Rodriguez Martinez, David Arribas-Layton, Christina Gerstner, Virginia S Muir, Kim S Midwood, Vivianne Malmström, Eddie A James, Jane H Buckne. Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis. JCI insight. vol 6. issue 5. 2021-08-23. PMID:33507879. |
tenascin-c (tnc), an extracellular matrix protein that has proinflammatory properties, is a recently described antibody target in rheumatoid arthritis (ra). |
2021-08-23 |
2023-08-13 |
human |