| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shao-Ting Chou, Fang Jung, Shih-Hsing Yang, Hwei-Ling Chou, Guey-Mei Jow, Jau-Chen Li. Antofine suppresses endotoxin-induced inflammation and metabolic disorder via AMP-activated protein kinase. Pharmacology research & perspectives. vol 5. issue 4. 2021-01-09. PMID:28805975. |
in addition, antofine can suppress the expressions of several inflammation-related genes (such as arg-1, il1f9, il-10, and il-33) and extracellular matrix genes (such as tnc and hyal1), as well as a vasopressor gene (edn1) in activated macrophage cells, that are induced by lps stimulation. |
2021-01-09 |
2023-08-13 |
human |
| Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Kanako Takano, Moriaki Kusakabe, Tatsuya Higash. Proof of Concept Study for Increasing Tenascin-C-Targeted Drug Delivery to Tumors Previously Subjected to Therapy: X-Irradiation Increases Tumor Uptake. Cancers. vol 12. issue 12. 2020-12-26. PMID:33291427. |
we selected the extracellular matrix glycoprotein tenascin-c (tnc) as such a molecule, and three antibodies recognizing human and murine tnc were employed to evaluate x-irradiation-induced changes in tnc uptake by subcutaneous tumors. |
2020-12-26 |
2023-08-13 |
human |
| Kyoko Imanaka-Yoshida, Isao Tawara, Toshimichi Yoshid. Tenascin-C in cardiac disease: a sophisticated controller of inflammation, repair, and fibrosis. American journal of physiology. Cell physiology. vol 319. issue 5. 2020-12-16. PMID:32845719. |
tenascin-c (tnc) is a large extracellular matrix glycoprotein classified as a matricellular protein that is generally upregulated at high levels during physiological and pathological tissue remodeling and is involved in important biological signaling pathways. |
2020-12-16 |
2023-08-13 |
mouse |
| Inbar Angel, Ori Pilo Kerman, Liat Rousso-Noori, Dinorah Friedmann-Morvinsk. Tenascin C promotes cancer cell plasticity in mesenchymal glioblastoma. Oncogene. vol 39. issue 46. 2020-12-11. PMID:33077835. |
our results uncover a link between nf-κb activation in mes gbm and high levels of tnc in gbm extracellular matrix. |
2020-12-11 |
2023-08-13 |
Not clear |
| Guoqiang Xu, Jianing Wei, Bing Huangfu, Jiping Gao, Xiaotang Wang, Lanfei Xiao, Ruijing Xuan, Zhaoyang Chen, Guohua Son. Animal model and bioinformatics analyses suggest the TIMP1/MMP9 axis as a potential biomarker in oral squamous cell carcinoma. Molecular carcinogenesis. vol 59. issue 11. 2020-12-01. PMID:33006223. |
gepia and ppi network analysis revealed that spp1, tnc, and acta1 were significantly related to tumor staging; spp1, tissue inhibitors of matrix metallopeptidases (mmps) 1 (timp1), and acta1 were closely related to prognosis. |
2020-12-01 |
2023-08-13 |
Not clear |
| Sandrine Gremlich, Matthias Roth-Kleiner, Lucile Equey, Kleanthis Fytianos, Johannes C Schittny, Tiziana P Cremon. Tenascin-C inactivation impacts lung structure and function beyond lung development. Scientific reports. vol 10. issue 1. 2020-11-25. PMID:32198404. |
tenascin-c (tnc) is an extracellular matrix protein expressed at high levels during lung organogenesis. |
2020-11-25 |
2023-08-13 |
mouse |
| Kei Hagiwara, Norifumi Harimoto, Takehiko Yokobori, Ryo Muranushi, Kouki Hoshino, Dorgormaa Gantumur, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Hiroshi Tanaka, Akira Watanabe, Norio Kubo, Kenichiro Araki, Yasuo Hosouchi, Ken Shirab. High Co-expression of Large Tenascin C Splice Variants in Stromal Tissue and Annexin A2 in Cancer Cell Membranes is Associated with Poor Prognosis in Pancreatic Cancer. Annals of surgical oncology. vol 27. issue 3. 2020-11-24. PMID:31463696. |
pancreatic cancer tissue contains abundant stromal components, including extracellular matrix proteins such as tenascin c (tnc), which exists as large (tnc-l) and non-large splice variants. |
2020-11-24 |
2023-08-13 |
human |
| Bastian L Gruber, Michael J Mienaltowski, James N MacLeod, Johannes Schittny, Stephanie Kasper, Martin Flüc. Tenascin-C expression controls the maturation of articular cartilage in mice. BMC research notes. vol 13. issue 1. 2020-11-23. PMID:32066496. |
expression of the de-adhesive extracellular matrix protein tenascin-c (tnc) is associated with the early postnatal development of articular cartilage which is both load-dependent and associated with chondrocyte differentiation. |
2020-11-23 |
2023-08-13 |
mouse |
| Dariusz Wawrzyniak, Małgorzata Grabowska, Paweł Głodowicz, Konrad Kuczyński, Bogna Kuczyńska, Agnieszka Fedoruk-Wyszomirska, Katarzyna Roll. Down-regulation of tenascin-C inhibits breast cancer cells development by cell growth, migration, and adhesion impairment. PloS one. vol 15. issue 8. 2020-10-15. PMID:32817625. |
tenascin-c (tnc) is an extracellular matrix (ecm) glycoprotein that plays an important role in cell proliferation, migration, and tumour invasion in various cancers. |
2020-10-15 |
2023-08-13 |
Not clear |
| Fatih Yalcin, Omar Dzaye, Shuli Xi. Tenascin-C Function in Glioma: Immunomodulation and Beyond. Advances in experimental medicine and biology. vol 1272. 2020-10-13. PMID:32845507. |
first identified in the 1980s, tenascin-c (tnc) is a multi-domain extracellular matrix glycoprotein abundantly expressed during the development of multicellular organisms. |
2020-10-13 |
2023-08-13 |
Not clear |
| Mina Yasuda, Norihiro Harada, Sonoko Harada, Ayako Ishimori, Yoko Katsura, Yukinari Itoigawa, Kei Matsuno, Fumihiko Makino, Jun Ito, Junya Ono, Kazunori Tobino, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Kazuhisa Takahash. Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology. vol 14. 2020-10-01. PMID:30473714. |
characterization of tenascin-c as a novel biomarker for asthma: utility of tenascin-c in combination with periostin or immunoglobulin e. extracellular matrix proteins tenascin-c (tnc) and periostin, which were identified as t-helper cell type 2 cytokine-induced genes in human bronchial epithelial cells, accumulate in the airway basement membrane of asthmatic patients. |
2020-10-01 |
2023-08-13 |
human |
| Fabio Morellini, Aleksey Malyshev, Maxim Volgushev, Marina Chistiakova, Giorgi Papashvili, Laetitia Fellini, Ralf Kleene, Melitta Schachner, Alexander Dityate. Impaired Fear Extinction Due to a Deficit in Ca Frontiers in integrative neuroscience. vol 11. 2020-09-30. PMID:28824389. |
impaired fear extinction due to a deficit in ca mice deficient in the extracellular matrix glycoprotein tenascin-c (tnc |
2020-09-30 |
2023-08-13 |
mouse |
| M A Codesido, Y Weil, M Liebergall, R Mosheiff, A Khour. Femoral neck pseudoarthrosis in a polio patient treated with closed reduction and cell therapy. Trauma case reports. vol 8. 2020-09-29. PMID:29644312. |
we report the case of a femoral neck fracture non-union after a missed femoral neck fracture in a polio affected leg treated with cannulated screws and percutaneous autologous injection of processed total nuclear cells (tnc) mixed with putty demineralized bone matrix. |
2020-09-29 |
2023-08-13 |
Not clear |
| Prachi Mishra, Michael A Kiebish, Jennifer Cullen, Alagarsamy Srinivasan, Aliyah Patterson, Rangaprasad Sarangarajan, Niven R Narain, Albert Dob. Genomic alterations of Tenascin C in highly aggressive prostate cancer: a meta-analysis. Genes & cancer. vol 10. issue 5-6. 2020-09-28. PMID:31798767. |
tenascin c (tnc), an extra-cellular matrix (ecm) family gene, is expressed in several cancer tissues of breast, lung, colon, and gastrointestinal tract leading to proliferation, migration, invasion, angiogenesis and metastasis, but its role in tumorigenesis of prostate cancer is poorly understood. |
2020-09-28 |
2023-08-13 |
Not clear |
| Zhaoting Yang, Chengye Zhang, Ying Feng, Mingji Quan, Yan Cui, Yanhua Xua. Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway. Cancer cell international. vol 20. 2020-09-28. PMID:32322169. |
tenascin-c (tnc) is an extracellular matrix protein that is widely expressed in the stromal fibroblasts of various cancers. |
2020-09-28 |
2023-08-13 |
Not clear |
| Juan L Vivero-Escoto, Hemapriyadarshini Vadarevu, Ridhima Juneja, Laura W Schrum, Jennifer H Benbo. Nanoparticle mediated silencing of tenascin C in hepatic stellate cells: effect on inflammatory gene expression and cell migration. Journal of materials chemistry. B. vol 7. issue 46. 2020-09-22. PMID:31701111. |
a pivotal event in the progression of liver fibrosis and cirrhosis is hepatic stellate cell (hsc) activation and secretion of extracellular matrix proteins, including tenascin-c (tnc). |
2020-09-22 |
2023-08-13 |
Not clear |
| Verena Haage, Nirmeen Elmadany, Lars Roll, Andreas Faissner, David H Gutmann, Marcus Semtner, Helmut Kettenman. Tenascin C regulates multiple microglial functions involving TLR4 signaling and HDAC1. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31271872. |
tenascin c (tnc) is an extracellular matrix glycoprotein, expressed in the cns during development, as well as in the setting of inflammation, fibrosis and cancer, which operates as an activator of toll-like receptor 4 (tlr4). |
2020-08-14 |
2023-08-13 |
Not clear |
| Kumiko Izumi, Nagisa Miyazaki, Hideshi Okada, Akiko Tsujimoto, Jun Matsumoto-Miyazaki, Junko Naito, Gakuro Yoshida, Ichijiro Murata, Kenshi Nagashima, Michiya Ohno, Kyoko Imanaka-Yoshida, Hiroyuki Okura, Hiroshige Ohashi, Genzou Takemur. Tenascin-C expression in renal biopsies from patients with tubulointerstitial nephritis and its relation to disease activity and prognosis. International journal of clinical and experimental pathology. vol 13. issue 7. 2020-08-14. PMID:32782713. |
tenascin-c (tnc) is an extracellular matrix protein that is transiently expressed in close association with tissue remodeling in various organs. |
2020-08-14 |
2023-08-13 |
Not clear |
| Longui Ning, Sha Li, Jianguo Gao, Liang Ding, Chenhui Wang, Wenguo Chen, Guodong Shan, Fenming Zhang, Jinghua Yu, Guoqiang X. Tenascin-C Is Increased in Inflammatory Bowel Disease and Is Associated with response to Infliximab Therapy. BioMed research international. vol 2019. 2020-05-13. PMID:31886172. |
tenascin-c (tnc) is an extracellular matrix glycoprotein expressed in response to inflammation and tissue damage. |
2020-05-13 |
2023-08-13 |
Not clear |
| J Qi, D R Esfahani, T Huang, P Ozark, E Bartom, R Hashizume, E R Bonner, S An, C M Horbinski, C D James, A M Saratsi. Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease. Acta neuropathologica communications. vol 7. issue 1. 2020-04-21. PMID:31092287. |
tnc is an extracellular matrix (ecm) glycoprotein that mediates cell-matrix interactions, guides migrating neurons during normal brain development and is thought to maintain the periventricular stem cell niche in the developing brain. |
2020-04-21 |
2023-08-13 |
Not clear |