| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideo Suzuki, Manabu Sasada, Sadahiro Kamiya, Yuka Ito, Hikaru Watanabe, Yuko Okada, Kazuma Ishibashi, Takuya Iyoda, Akinori Yanaka, Fumio Fuka. The Promoting Effect of the Extracellular Matrix Peptide TNIIIA2 Derived from Tenascin-C in Colon Cancer Cell Infiltration. International journal of molecular sciences. vol 18. issue 1. 2017-04-24. PMID:28106752. |
the extracellular matrix (ecm) molecule tenascin c (tnc) is known to be highly expressed under various pathological conditions such as inflammation and cancer. |
2017-04-24 |
2023-08-13 |
Not clear |
| Chengzhi Li, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Huaxin Wang, Liang Shi, Jinxiang Ha. Tenascin C affects mineralization of SaOS2 osteoblast-like cells through matrix vesicles. Drug discoveries & therapeutics. vol 10. issue 2. 2017-01-24. PMID:26961327. |
tenascin c (tnc) is an extracellular matrix glycoprotein involved in osteogenesis and bone mineralization. |
2017-01-24 |
2023-08-13 |
Not clear |
| Chengzhi Li, Yazhou Cui, Jing Luan, Xiaoyan Zhou, Haiying Li, Huaxin Wang, Liang Shi, Jinxiang Ha. Tenascin C affects mineralization of SaOS2 osteoblast-like cells through matrix vesicles. Drug discoveries & therapeutics. vol 10. issue 2. 2017-01-24. PMID:26961327. |
in a previous study, we identified tnc protein located in the matrix vesicles (mvs) of osteoblasts. |
2017-01-24 |
2023-08-13 |
Not clear |
| Shuli Xia, Bachchu Lal, Brian Tung, Shervin Wang, C Rory Goodwin, John Laterr. Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation. Neuro-oncology. vol 18. issue 4. 2016-12-13. PMID:26320116. |
in this work, we have investigated the effect of alterations in brain tumor extracellular matrix tenascin-c (tnc) on brain tumor growth patterns including proliferation and invasion. |
2016-12-13 |
2023-08-13 |
Not clear |
| Masashi Fujimoto, Masato Shiba, Fumihiro Kawakita, Lei Liu, Naoshi Shimojo, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Hidenori Suzuk. Deficiency of tenascin-C and attenuation of blood-brain barrier disruption following experimental subarachnoid hemorrhage in mice. Journal of neurosurgery. vol 124. issue 6. 2016-12-13. PMID:26473781. |
mice were examined by means of neuroscore and brain water content 24-48 hours post-sah; and evans blue dye extravasation and western blotting of tnc, matrix metalloproteinase (mmp)-9, and zona occludens (zo)-1 at 24 hours post-sah. |
2016-12-13 |
2023-08-13 |
mouse |
| Zhanhu Zhang, Bin Yu, Yun Gu, Songlin Zhou, Tianmei Qian, Yongjun Wang, Guohui Ding, Fei Ding, Xiaosong G. Fibroblast-derived tenascin-C promotes Schwann cell migration through β1-integrin dependent pathway during peripheral nerve regeneration. Glia. vol 64. issue 3. 2016-10-06. PMID:26497118. |
in this study, microarray analysis revealed that a total of 6,046 genes were differentially expressed in the proximal nerve segment after sciatic nerve transection in rats, and bioinformatics analysis further identified tenascin-c (tnc), an extracellular matrix (ecm) protein, as a key gene regulator. |
2016-10-06 |
2023-08-13 |
rat |
| Azhar Maqbool, Emma J Spary, Iain W Manfield, Michaela Ruhmann, Lorena Zuliani-Alvarez, Filomena O Gamboa-Esteves, Karen E Porter, Mark J Drinkhill, Kim S Midwood, Neil A Turne. Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4. World journal of cardiology. vol 8. issue 5. 2016-05-27. PMID:27231521. |
to investigate the effect of tenascin c (tnc) on the expression of pro-inflammatory cytokines and matrix metalloproteinases in human cardiac myofibroblasts (cmf). |
2016-05-27 |
2023-08-13 |
human |
| Jennifer H Benbow, Kyle J Thompson, Heidi L Cope, Elizabeth Brandon-Warner, Catherine R Culberson, Krista L Bossi, Ting Li, Mark W Russo, Keith S Gersin, Iain H McKillop, Andrew S deLemos, Laura W Schru. Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling. The American journal of pathology. vol 186. issue 1. 2016-05-10. PMID:26603137. |
tenascin-c (tnc), an extracellular matrix protein, is transiently expressed during tissue injury and plays a role in fibrogenesis and tumorigenesis. |
2016-05-10 |
2023-08-13 |
mouse |
| Vasundhara Kain, Kevin A Ingle, Romain A Colas, Jesmond Dalli, Sumanth D Prabhu, Charles N Serhan, Medha Joshi, Ganesh V Halad. Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function. Journal of molecular and cellular cardiology. vol 84. 2016-04-07. PMID:25870158. |
rvd1 reduced the pro-fibrotic genes (colla1, coll2a1 and tnc (all; p < 0.05)) and decreased collagen deposition, thereby reducing post-mi fibrosis and thus stabilizing the extracellular matrix. |
2016-04-07 |
2023-08-13 |
mouse |
| Stefan Wiese, Andreas Faissne. The role of extracellular matrix in spinal cord development. Experimental neurology. vol 274. issue Pt B. 2016-04-06. PMID:26028310. |
recent research has also provided strong evidence that depletion of single matrix molecules like tenascin c (tnc) can lead to developmental changes within the progenitor pools. |
2016-04-06 |
2023-08-13 |
Not clear |
| Susobhan Sarkar, Franz J Zemp, Donna Senger, Stephen M Robbins, V Wee Yon. ADAM-9 is a novel mediator of tenascin-C-stimulated invasiveness of brain tumor-initiating cells. Neuro-oncology. vol 17. issue 8. 2016-03-24. PMID:25646025. |
tenascin-c (tnc), an extracellular matrix protein overexpressed in malignant gliomas, stimulates invasion of conventional glioma cell lines (u251, u87). |
2016-03-24 |
2023-08-13 |
Not clear |
| Anuj Shukla, Priyanka Gaur, Amita Aggarwa. Tenascin-C Levels, A Toll-like Receptor 4 Ligand, in Enthesitis-related Arthritis Category of Juvenile Idiopathic Arthritis: A Cross-sectional and Longitudinal Study. The Journal of rheumatology. vol 42. issue 5. 2016-03-24. PMID:25774061. |
tenascin-c (tnc) is an extracellular matrix glycoprotein and acts as an endogenous tlr4 ligand. |
2016-03-24 |
2023-08-13 |
Not clear |
| Pinar Ozmen Yildiz, Ibrahim Yildiz, Caglar Ozmen, Mustafa Karabacak, Oben Dove. Relation between coronary artery calcium score and serum tenascin-C level in patients without known coronary artery disease. Acta cardiologica. vol 70. issue 6. 2016-02-18. PMID:26717210. |
tenascin-c (tnc), an extracellular matrix glycoprotein is normally found in very low concentrations in tissues and serum of adults, whereas its expression is enhanced in case of pathological conditions accompanied by inflammation. |
2016-02-18 |
2023-08-13 |
human |
| Mariana Muñoz-Esquerre, Daniel Huertas, Ignacio Escobar, Marta López-Sánchez, Rosa Penín, Victor Peinado, Joan Albert Barberà, María Molina-Molina, Frederic Manresa, Jordi Dorca, Salud Santo. Gene and Protein Expression of Fibronectin and Tenascin-C in Lung Samples from COPD Patients. Lung. vol 193. issue 3. 2016-02-11. PMID:25794567. |
fibronectin (fn) and tenascin-c (tnc) are two extracellular matrix proteins associated with remodeling changes. |
2016-02-11 |
2023-08-13 |
human |
| Meiyan Shi, Xiaodan He, Wei Wei, Juan Wang, Ti Zhang, Xiaohong She. Tenascin-C induces resistance to apoptosis in pancreatic cancer cell through activation of ERK/NF-κB pathway. Apoptosis : an international journal on programmed cell death. vol 20. issue 6. 2016-01-04. PMID:25690319. |
as a glycol-protein located in extracellular matrix (ecm), tenascin-c (tnc) is absent in most normal adult tissues but is highly expressed in the majority of malignant solid tumors. |
2016-01-04 |
2023-08-13 |
human |
| Meiyan Shi, Xiaodan He, Wei Wei, Juan Wang, Ti Zhang, Xiaohong She. Tenascin-C induces resistance to apoptosis in pancreatic cancer cell through activation of ERK/NF-κB pathway. Apoptosis : an international journal on programmed cell death. vol 20. issue 6. 2016-01-04. PMID:25690319. |
the present study indicated tnc in cellular matrix induces an activation of erk1/2/nf-κb/p65 signaling cascade and thereby mediates resistance to apoptosis in pancreatic cancer. |
2016-01-04 |
2023-08-13 |
human |
| Alex A Pollen, Tomasz J Nowakowski, Jiadong Chen, Hanna Retallack, Carmen Sandoval-Espinosa, Cory R Nicholas, Joe Shuga, Siyuan John Liu, Michael C Oldham, Aaron Diaz, Daniel A Lim, Anne A Leyrat, Jay A West, Arnold R Kriegstei. Molecular identity of human outer radial glia during cortical development. Cell. vol 163. issue 1. 2015-12-22. PMID:26406371. |
by analyzing gene expression across single cells, we find that outer radial glia preferentially express genes related to extracellular matrix formation, migration, and stemness, including tnc, ptprz1, fam107a, hopx, and lifr. |
2015-12-22 |
2023-08-13 |
human |
| Caroline Spenlé, Isabelle Gasser, Falk Saupe, Klaus-Peter Janssen, Christiane Arnold, Annick Klein, Michael van der Heyden, Jérome Mutterer, Agnès Neuville-Méchine, Marie-Pierre Chenard, Dominique Guenot, Iréne Esposito, Julia Slotta-Huspenina, Noona Ambartsumian, Patricia Simon-Assmann, Gertraud Oren. Spatial organization of the tenascin-C microenvironment in experimental and human cancer. Cell adhesion & migration. vol 9. issue 1-2. 2015-12-16. PMID:25611571. |
the extracellular matrix (ecm) molecule tenascin-c (tnc) promotes tumor progression. |
2015-12-16 |
2023-08-13 |
human |
| Caroline Spenlé, Isabelle Gasser, Falk Saupe, Klaus-Peter Janssen, Christiane Arnold, Annick Klein, Michael van der Heyden, Jérome Mutterer, Agnès Neuville-Méchine, Marie-Pierre Chenard, Dominique Guenot, Iréne Esposito, Julia Slotta-Huspenina, Noona Ambartsumian, Patricia Simon-Assmann, Gertraud Oren. Spatial organization of the tenascin-C microenvironment in experimental and human cancer. Cell adhesion & migration. vol 9. issue 1-2. 2015-12-16. PMID:25611571. |
we found that tnc is organized in matrix tracks together with other ecm molecules of the angiomatrix signature, a previously described gene expression profile that characterizes the angiogenic switch. |
2015-12-16 |
2023-08-13 |
human |
| Camille M Lowy, Thordur Oskarsso. Tenascin C in metastasis: A view from the invasive front. Cell adhesion & migration. vol 9. issue 1-2. 2015-12-16. PMID:25738825. |
the extracellular matrix protein tenascin c (tnc) is a large glycoprotein expressed in connective tissues and stem cell niches. |
2015-12-16 |
2023-08-13 |
mouse |