| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tina P Dale, Shazia Mazher, William R Webb, Jing Zhou, Nicola Maffulli, Guo-Qiang Chen, Alicia J El Haj, Nicholas R Forsyt. Tenogenic Differentiation of Human Embryonic Stem Cells. Tissue engineering. Part A. vol 24. issue 5-6. 2018-12-11. PMID:28548630. |
conversely, when hescs were cultured in the presence of bmp12/13 and dorsomorphin col3a1, dcn, and tnc gene expression and tendon matrix formation were inhibited. |
2018-12-11 |
2023-08-13 |
human |
| Sean P Giblin, Devadarssen Murdamoothoo, Claire Deligne, Anja Schwenzer, Gertraud Orend, Kim S Midwoo. How to detect and purify tenascin-C. Methods in cell biology. vol 143. 2018-11-14. PMID:29310788. |
the extracellular matrix molecule tenascin-c (tnc) was discovered over 30 years ago, and its tightly regulated pattern of expression since sparked keen interest in the scientific community. |
2018-11-14 |
2023-08-13 |
Not clear |
| Sean P Giblin, Devadarssen Murdamoothoo, Claire Deligne, Anja Schwenzer, Gertraud Orend, Kim S Midwoo. How to detect and purify tenascin-C. Methods in cell biology. vol 143. 2018-11-14. PMID:29310788. |
because studying the expression of this large matrix molecule is not always straightforward, here we describe basic techniques to examine tissue levels of tnc mrna and protein. |
2018-11-14 |
2023-08-13 |
Not clear |
| Devadarssen Murdamoothoo, Anja Schwenzer, Jessica Kant, Tristan Rupp, Anna Marzeda, Kim Midwood, Gertraud Oren. Investigating cell-type specific functions of tenascin-C. Methods in cell biology. vol 143. 2018-11-14. PMID:29310789. |
the extracellular matrix molecule tenascin-c (tnc) has received a lot of attention since its discovery 30 years ago because of its multiple roles in tissue repair, and in pathologies such as chronic inflammation, fibrosis, and cancer. |
2018-11-14 |
2023-08-13 |
mouse |
| Jennifer H Benbow, April D Elam, Krista L Bossi, Danae L Massengill, Elizabeth Brandon-Warner, William E Anderson, Catherine R Culberson, Mark W Russo, Andrew S deLemos, Laura W Schru. Analysis of Plasma Tenascin-C in Post-HCV Cirrhosis: A Prospective Study. Digestive diseases and sciences. vol 63. issue 3. 2018-05-18. PMID:29330728. |
hepatic stellate cell activation, a pivotal event in cirrhosis development, results in increased secretion of extracellular matrix proteins, including tenascin-c (tnc). |
2018-05-18 |
2023-08-13 |
Not clear |
| V Stamenkovic, I Milenkovic, N Galjak, V Todorovic, P Andju. Enriched environment alters the behavioral profile of tenascin-C deficient mice. Behavioural brain research. vol 331. 2018-04-03. PMID:28549651. |
tenascin-c (tnc) is an extracellular matrix glycoprotein implicated in a variety of processes ranging from brain development to synaptic plasticity in the adult vertebrates. |
2018-04-03 |
2023-08-13 |
mouse |
| Katrin Gutsche, Elisa B Randi, Volker Blank, Daniel Fink, Roland H Wenger, Cornelia Leo, Carsten C Schol. Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells. Free radical biology & medicine. vol 101. 2017-12-25. PMID:27717868. |
gene array analysis of ibc cells following chronic ih (45-60 days) demonstrated increased expression of pro-metastatic genes of the extracellular matrix, such as tenascin-c (tnc; an essential factor of the metastatic niche) and matrix metalloproteinase 9 (mmp9), and of pro-inflammatory processes, such as cyclooxygenase-2 (cox-2). |
2017-12-25 |
2023-08-13 |
Not clear |
| Kaori Matsumoto, Yuji Nakai, Masaru Hoshino, Koki Yamazaki, Yoshiaki Takioto, Satoru Takadera, Takayuki Nakagawa, Ryohei Nishimura, Moriaki Kusakab. Comprehensive DNA microarray expression profiles of tumors in tenascin-C-knockout mice. Bioscience, biotechnology, and biochemistry. vol 81. issue 10. 2017-10-17. PMID:28874093. |
tenascin-c (tnc), an extracellular matrix glycoprotein, plays a pivotal role in tumor growth. |
2017-10-17 |
2023-08-13 |
mouse |
| Vera Stamenkovic, Stefan Stamenkovic, Tomasz Jaworski, Maciej Gawlak, Milos Jovanovic, Igor Jakovcevski, Grzegorz M Wilczynski, Leszek Kaczmarek, Melitta Schachner, Lidija Radenovic, Pavle R Andju. The extracellular matrix glycoprotein tenascin-C and matrix metalloproteinases modify cerebellar structural plasticity by exposure to an enriched environment. Brain structure & function. vol 222. issue 1. 2017-10-16. PMID:27089885. |
the importance of the extracellular matrix (ecm) glycoprotein tenascin-c (tnc) and the ecm degrading enzymes, matrix metalloproteinases (mmps) -2 and -9, in cerebellar histogenesis is well established. |
2017-10-16 |
2023-08-13 |
mouse |
| Susobhan Sarkar, Reza Mirzaei, Franz J Zemp, Wu Wei, Donna L Senger, Stephen M Robbins, V Wee Yon. Activation of NOTCH Signaling by Tenascin-C Promotes Growth of Human Brain Tumor-Initiating Cells. Cancer research. vol 77. issue 12. 2017-09-14. PMID:28416488. |
here we provide evidence that tenascin-c (tnc), an extracellular matrix protein prominent in malignant glioma, increases notch activity in btic to promote their growth. |
2017-09-14 |
2023-08-13 |
human |
| Susobhan Sarkar, Reza Mirzaei, Franz J Zemp, Wu Wei, Donna L Senger, Stephen M Robbins, V Wee Yon. Activation of NOTCH Signaling by Tenascin-C Promotes Growth of Human Brain Tumor-Initiating Cells. Cancer research. vol 77. issue 12. 2017-09-14. PMID:28416488. |
in tissue culture, tnc was superior amongst several extracellular matrix proteins in enhancing the sphere-forming capacity of glioma patient-derived btic. |
2017-09-14 |
2023-08-13 |
human |
| Yang Lin, Eric A Lewallen, Emily T Camilleri, Carolina A Bonin, Dakota L Jones, Amel Dudakovic, Catalina Galeano-Garces, Wei Wang, Marcel J Karperien, Annalise N Larson, Diane L Dahm, Michael J Stuart, Bruce A Levy, Jay Smith, Daniel B Ryssman, Jennifer J Westendorf, Hee-Jeong Im, Andre J van Wijnen, Scott M Riester, Aaron J Kryc. RNA-seq analysis of clinical-grade osteochondral allografts reveals activation of early response genes. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 34. issue 11. 2017-08-28. PMID:26909883. |
our studies establish reduced levels of mrnas encoding cartilage related extracellular matrix (ecm) proteins (i.e., col1a1, col2a1, col10a1, acan, dcn, hapln1, tnc, and comp) in stored cartilage. |
2017-08-28 |
2023-08-13 |
Not clear |
| b' Miljana Mom\\xc4\\x8dilovi\\xc4\\x87, Vera Stamenkovi\\xc4\\x87, Milo\\xc5\\xa1 Jovanovi\\xc4\\x87, Pavle R Andjus, Igor Jakov\\xc4\\x8devski, Melitta Schachner, \\xc4\\x90or\\xc4\\x91e Miljkovi\\xc4\\x8. Tenascin-C deficiency protects mice from experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 302. 2017-08-14. PMID:27974153.' |
the extracellular matrix glycoprotein tenascin-c (tnc) has been increasingly appreciated as a molecule susceptibly reacting to abnormalities in the mammalian immune system. |
2017-08-14 |
2023-08-13 |
mouse |
| Paulo Santoro Belangero, Mariana Ferreira Leal, Eduardo Antônio Figueiredo, Carina Cohen, Carlos Vicente Andreoli, Marília Cardoso Smith, Alberto de Castro Pochini, Benno Ejnisman, Moises Cohe. Differential expression of extracellular matrix genes in glenohumeral capsule of shoulder instability patients. Connective tissue research. vol 57. issue 4. 2017-08-09. PMID:27093129. |
we evaluated the expression of genes that encode the cartilage oligomeric matrix protein (comp), fibronectin 1 (fn1), tenascin c (tnc) and tenascin xb (tnxb) in the glenohumeral capsule of anterior shoulder instability patients and controls. |
2017-08-09 |
2023-08-13 |
Not clear |
| Zhaoting Yang, Weidong Ni, Chunai Cui, Longyun Fang, Yanhua Xua. Tenascin C is a prognostic determinant and potential cancer-associated fibroblasts marker for breast ductal carcinoma. Experimental and molecular pathology. vol 102. issue 2. 2017-08-09. PMID:28223108. |
tenascin c (tnc) is a key of extracellular matrix glycoprotein and highly express in numerous human malignancies. |
2017-08-09 |
2023-08-13 |
human |
| Kim S Midwood, Matthias Chiquet, Richard P Tucker, Gertraud Oren. Tenascin-C at a glance. Journal of cell science. vol 129. issue 23. 2017-07-31. PMID:27875272. |
tenascin-c (tnc) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. |
2017-07-31 |
2023-08-13 |
Not clear |
| Carina Cohen, Mariana Ferreira Leal, Paulo Santoro Belangero, Eduardo Antônio Figueiredo, Marília Cardoso Smith, Carlos Vicente Andreoli, Alberto de Castro Pochini, Moises Cohen, Benno Ejnisman, Flávio Falopp. The roles of Tenascin C and Fibronectin 1 in adhesive capsulitis: a pilot gene expression study. Clinics (Sao Paulo, Brazil). vol 71. issue 6. 2017-06-27. PMID:27438566. |
we evaluated mrna expression levels of genes that encode tgf-β1; the tgf-β1 receptor; the collagen-modifying enzymes lox, plod1, and plod2; and the extracellular matrix proteins comp, fn1, tnc and tnxb in synovial/capsule specimens from patients with idiopathic adhesive capsulitis. |
2017-06-27 |
2023-08-13 |
Not clear |
| Anja Schrade, Antti Kyrönlahti, Oyediran Akinrinade, Marjut Pihlajoki, Simon Fischer, Verena Martinez Rodriguez, Kerstin Otte, Vidya Velagapudi, Jorma Toppari, David B Wilson, Markku Heikinheim. GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells. Endocrinology. vol 157. issue 6. 2017-06-05. PMID:26974005. |
depletion of gata4 in tm4 cells and primary scs was associated with altered expression of genes involved in key facets of btb maintenance, including tight/adherens junction formation (tjp1, cldn12, vcl, tnc, csk) and extracellular matrix reorganization (lamc1, col4a1, col4a5, mmp10, mmp23, timp2). |
2017-06-05 |
2023-08-13 |
mouse |
| Wei-Dong Ni, Zhao-Ting Yang, Chun-Ai Cui, Yan Cui, Long-Yun Fang, Yan-Hua Xua. Tenascin-C is a potential cancer-associated fibroblasts marker and predicts poor prognosis in prostate cancer. Biochemical and biophysical research communications. vol 486. issue 3. 2017-06-02. PMID:28341124. |
tenascin-c (tnc), as a member of the extracellular matrix (ecm), plays an important role in cancer cell proliferation and migration and tumor invasion in various types of cancer. |
2017-06-02 |
2023-08-13 |
Not clear |
| Haiyan Fu, Yuan Tian, Lili Zhou, Dong Zhou, Roderick J Tan, Donna B Stolz, Youhua Li. Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis. Journal of the American Society of Nephrology : JASN. vol 28. issue 3. 2017-05-31. PMID:27612995. |
here, we determined whether tenascin-c (tnc), an extracellular matrix glycoprotein, is a component of the fibrogenic niche in kidney fibrosis. |
2017-05-31 |
2023-08-13 |
Not clear |