| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Derycke, N Zhang, G Holtappels, T Dutré, C Bacher. IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. vol 11. issue 3. 2012-11-06. PMID:22178076. |
nasal polyps in adults are characterized by a chronic inflammation of the upper airways and by the preferential activation of th2 cells. |
2012-11-06 |
2023-08-12 |
Not clear |
| Teodor T Postolache, Hirsh Komarow, Leonardo H Tonell. Allergy: a risk factor for suicide? Current treatment options in neurology. vol 10. issue 5. 2012-10-02. PMID:18782509. |
our recent report of th2 (allergy-mediating) cytokine expression in the orbitofrontal cortex of suicide victims should lead to future studies to test the hypothesis that mediators of allergic inflammation in the nasal cavities may result in th2 cytokine expression in the brain, influencing affect and behavioral modulation. |
2012-10-02 |
2023-08-12 |
rat |
| Rogerio Pezato, Richard Louis Voegel. Why do we not find polyps in the lungs? Bronchial mucosa as a model in the treatment of polyposis. Medical hypotheses. vol 78. issue 4. 2012-06-28. PMID:22289339. |
nasal polyposis and asthma share basically the same inflammatory process: predominant infiltration of eosinophils, mucus cell hyperplasia, edema, thickened basal membrane, polarization for th2 cell immune response, similar pro-inflammatory mediators are increased, for example cysteinyl leukotrienes. |
2012-06-28 |
2023-08-12 |
Not clear |
| Anne Månsson Kvarnhammar, Camilla Rydberg, Malin Järnkrants, Mia Eriksson, Rolf Uddman, Mikael Benson, Lars-Olaf Cardel. Diminished levels of nasal S100A7 (psoriasin) in seasonal allergic rhinitis: an effect mediated by Th2 cytokines. Respiratory research. vol 13. 2012-06-22. PMID:22230654. |
diminished levels of nasal s100a7 (psoriasin) in seasonal allergic rhinitis: an effect mediated by th2 cytokines. |
2012-06-22 |
2023-08-12 |
Not clear |
| Y H Kim, T Y Yang, C-S Park, S-H Ahn, B K Son, J H Kim, D H Lim, T Y Jan. Anti-IL-33 antibody has a therapeutic effect in a murine model of allergic rhinitis. Allergy. vol 67. issue 2. 2012-05-07. PMID:22050307. |
interleukin (il)-33 is involved in the th2 immune response and could play an essential role in nasal allergy. |
2012-05-07 |
2023-08-12 |
Not clear |
| Yi Zheng, Changyuan Guo, Yan Zhang, Hui Qi, Qianying Sun, Enquan Xu, Yingmei Zhang, Dalong Ma, Ying Wan. Alleviation of murine allergic rhinitis by C19, a C-terminal peptide of chemokine-like factor 1 (CKLF1). International immunopharmacology. vol 11. issue 12. 2012-04-13. PMID:22001899. |
c19 was able to suppress the th2 cytokine il-4 without augmenting the th1 cytokine ifn-γ in bal and il-4(+) cells in the local nasal tissue. |
2012-04-13 |
2023-08-12 |
mouse |
| S Langier, R Landsberg, K Sade, S Kivit. Anti-IL-5 immunomodulates the effect of Staphylococcus aureus enterotoxin on T cell response in nasal polyps. Rhinology. vol 49. issue 5. 2012-03-27. PMID:22125788. |
chronic rhinosinusitis with nasal polyps (crswnp) is a t helper-2 (th2) inflammatory disease with considerable impact on the quality of life. |
2012-03-27 |
2023-08-12 |
Not clear |
| Victor J Johnson, Jeffrey S Reynolds, Wei Wang, Kara Fluharty, Berran Yuceso. Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in mice. Journal of allergy. vol 2011. 2011-11-10. PMID:21785612. |
expression of th2 (il-4, il-5, and il-13) and anti/proinflammatory (il-10, tnfα, and il-1β) cytokine genes was upregulated in the lymph nodes and the nasal mucosa. |
2011-11-10 |
2023-08-12 |
mouse |
| Ruby Pawankar, Sachiko Mori, Chika Ozu, Satoko Kimur. Overview on the pathomechanisms of allergic rhinitis. Asia Pacific allergy. vol 1. issue 3. 2011-11-10. PMID:22053313. |
the inflammatory response in the nasal mucosa includes an immediate ige-mediated mast cell response as well as a latephase response characterized by recruitment of eosinophils, basophils, and t cells expressing th2 cytokines including interleukin (il)-4, a switch factor for ige synthesis, and il-5, an eosinophil growth factor and on-going allergic inflammation. |
2011-11-10 |
2023-08-12 |
Not clear |
| b' A Peri\\xc4\\x87, D Vojvodi\\xc4\\x87, V Radulovi\\xc4\\x87, B Vukomanovi\\xc4\\x87-\\xc4\\x90ur\\xc4\\x91evi\\xc4\\x87, O Miljanovi\\xc4\\x8. Correlation between cytokine levels in nasal fluid and eosinophil counts in nasal polyp tissue in asthmatic and non-asthmatic patients. Allergologia et immunopathologia. vol 39. issue 3. 2011-10-17. PMID:21211895.' |
so, the aim of our study was to evaluate local immune reaction by measuring crucial th1, th2 and inflammatory cytokines in nasal fluid samples of patients with nasal polyps (np), and to correlate them to clinical, radiological findings and to the degree of eosinophil infiltration of polyp tissue. |
2011-10-17 |
2023-08-12 |
Not clear |
| Ji Shen, Suling Hon. [Serum levels of IL-12, IL-4 and pathologic changes by scanning electron microscope of nasal mucous inflammation]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 24. issue 20. 2011-10-13. PMID:21171294. |
the serum levels of interleukin-4, interleukin-12 will be detected to elucidate and compare the involvement of th1 and th2 cells and the surface structures of nasal mucosa will also be observed in patients with allergic rhinitis (ar), chronic rhinosinusitis with nasal polyps (crswnp), chronic rhinosinusitis without nasal polyps (crssnp) and nasal septal deviation (nsd) to obtain the characteristics and regularity of pathological changes. |
2011-10-13 |
2023-08-12 |
Not clear |
| b' Aleksandar Peri\\xc4\\x87, Danilo Vojvodi\\xc4\\x87, Vesna Radulovi\\xc4\\x87, Biserka Vukomanovi\\xc4\\x87-Durdevi\\xc4\\x87, Aneta V Peri\\xc4\\x87, Olivera Miljanovi\\xc4\\x8. Proinflammatory cytokine levels in nasal fluid as indicators of severity of nasal polyposis. Acta clinica Croatica. vol 49. issue 4. 2011-09-15. PMID:21830450.' |
the concentrations of th2 proinflammatory cytokines il-5 and il-6 were significantly higher (p < 0.05 and p < 0.01, respectively) in patients with nasal polyposis and asthma compared with nasal polyp patients without asthma. |
2011-09-15 |
2023-08-12 |
human |
| J K Mulligan, B S Bleier, B O'Connell, R M Mulligan, C Wagner, R J Schlosse. Vitamin D3 correlates inversely with systemic dendritic cell numbers and bone erosion in chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis. Clinical and experimental immunology. vol 164. issue 3. 2011-07-18. PMID:21401575. |
we hypothesized that t helper type 2 (th2) disorders, chronic rhinosinusitis with nasal polyps (crswnp) and allergic fungal rhinosinusitis (afrs) would have vd(3) deficiencies, resulting in increased mature dendritic cells (dcs) and bone erosion. |
2011-07-18 |
2023-08-12 |
Not clear |
| Seung-Heon Shin, Mi-Kyung Y. Th2 responses elicited by nasal epithelial cells exposed to house dust mite extract. Clinical and experimental otorhinolaryngology. vol 2. issue 4. 2011-07-14. PMID:20072691. |
th2 responses elicited by nasal epithelial cells exposed to house dust mite extract. |
2011-07-14 |
2023-08-12 |
Not clear |
| Satoko Kimura, Ruby Pawankar, Sachiko Mori, Manabu Nonaka, Satoru Masuno, Toshiaki Yagi, Kimihiro Okub. Increased expression and role of thymic stromal lymphopoietin in nasal polyposis. Allergy, asthma & immunology research. vol 3. issue 3. 2011-07-14. PMID:21738884. |
nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, th2 type lymphocytes, fibroblasts, goblet cells and mast cells. |
2011-07-14 |
2023-08-12 |
Not clear |
| O Krysko, G Holtappels, N Zhang, M Kubica, K Deswarte, L Derycke, S Claeys, H Hammad, G G Brusselle, P Vandenabeele, D V Krysko, C Bacher. Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis. Allergy. vol 66. issue 3. 2011-05-23. PMID:20973804. |
chronic rhinosinusitis with nasal polyps (crswnp) is characterized by biased th2 inflammation and crs without nasal polyps (crssnp) by a th1 immune response. |
2011-05-23 |
2023-08-12 |
Not clear |
| Douglas D Reh, Murugappan Ramanathan, Babar Sultan, Yadong Wang, Lindsey May, Andrew P Lan. The role of hepatocyte growth factor/c-Met in chronic rhinosinusitis with nasal polyps. American journal of rhinology & allergy. vol 24. issue 4. 2011-03-15. PMID:20819464. |
the effect of hgf on human sinonasal epithelial cell (snec) responses to th2 inflammatory cytokines in chronic rhinosinusitis with nasal polyps (crswnp) has not been explored. |
2011-03-15 |
2023-08-12 |
human |
| David H Broid. Allergic rhinitis: Pathophysiology. Allergy and asthma proceedings. vol 31. issue 5. 2011-02-07. PMID:20929602. |
the inflammatory response in the nasal mucosa in subjects with allergic rhinitis challenged intranasally with an allergen includes an immediate ige-mediated mast cell response as well as a late-phase response characterized by recruitment of eosinophils, basophils, and t cells expressing th2 cytokines including il-4, a switch factor for ige synthesis, and il-5, an eosinophil growth factor. |
2011-02-07 |
2023-08-12 |
human |
| David H Broid. Allergic rhinitis: Pathophysiology. Allergy and asthma proceedings. vol 31. issue 5. 2011-02-07. PMID:20929602. |
recent advances have suggested that additional pathways may contribute to the pathophysiology of allergic rhinitis including local synthesis of ige in the nasal mucosa, the epithelial expression of cytokines that regulate th2 cytokine responses (i.e., thymic stromal lymphopoietin, il-25, and il-33), and the activation of histamine receptors other than h₁ and h₂ such as h₄-histamine receptors. |
2011-02-07 |
2023-08-12 |
human |
| H Suzuki, H Kakutani, M Kondoh, A Watari, K Yag. The safety of a mucosal vaccine using the C-terminal fragment of Clostridium perfringens enterotoxin. Die Pharmazie. vol 65. issue 10. 2011-01-06. PMID:21105580. |
nasal immunization with c-cpe-fused ova (5 microg of ova) activated th1 and th2 responses. |
2011-01-06 |
2023-08-12 |
mouse |