| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Hetenyi, N Kovacevic, S E Hall, M Vrani. Plasma glucagon in pups, decreased by fasting, unaffected by somatostatin or hypoglycemia. The American journal of physiology. vol 231. issue 5 Pt. 1. 1977-01-29. PMID:998780. |
in pups, somatostatin did not decrease the plasma concentration of either irg or immunoreactive insulin (iri) and caused no change in plasma glucose or in the rates of glucose production and utilization calculated from experiments with tracers. |
1977-01-29 |
2023-08-11 |
Not clear |
| A Luyck. [The role of glucagon in hyperglycemia. A review (author's transl)]. Diabete & metabolisme. vol 1. issue 3. 1977-01-28. PMID:791728. |
finally, in insulin-dependant diabetics, somatostatin infusion reduces plasma glucagon concentration and blood glucose and prevents the development of ketosis after withdrawal of insulin therapy. |
1977-01-28 |
2023-08-11 |
Not clear |
| G Porzio, F Massara, F Camanni, G Rizzi, G M Molinatt. [Effects of somatostatin of plasma levels of glucose, insulin and growth hormone in acromegaly]. Minerva medica. vol 67. issue 50. 1977-01-28. PMID:995281. |
[effects of somatostatin of plasma levels of glucose, insulin and growth hormone in acromegaly]. |
1977-01-28 |
2023-08-11 |
Not clear |
| O D Hegre, R J Leonard, S L Erlandsen, R C McEvoy, J A Parsons, R P Elde, A Lazaro. Transplantation of islet tissue in the rat. Acta endocrinologica. Supplementum. vol 205. 1977-01-25. PMID:826063. |
utilization of the more specific unlabeled immunoperoxidase method has revealed that some of the transplanted islets are composed of cells positive for glucagon and somatostatin, as well as insulin. |
1977-01-25 |
2023-08-11 |
rat |
| O D Hegre, R J Leonard, S L Erlandsen, R C McEvoy, J A Parsons, R P Elde, A Lazaro. Transplantation of islet tissue in the rat. Acta endocrinologica. Supplementum. vol 205. 1977-01-25. PMID:826063. |
the presence of insulin, glucagon, somatostatin, and delete pancreatic polypeptide positive cells in the islets of normal rat pancreas has been confirmed. |
1977-01-25 |
2023-08-11 |
rat |
| S J Bhathena, P V Perrino, N R Voyles, S S Smith, S D Wilkins, D H Coy, A V Schally, L Recan. Reversal of somatostatin inhibition of insulin and glucagon secretion. Diabetes. vol 25. issue 11. 1977-01-25. PMID:992224. |
reversal of somatostatin inhibition of insulin and glucagon secretion. |
1977-01-25 |
2023-08-11 |
rat |
| A D Cherrington, J L Chiasson, J E Liljenquist, A S Jennings, U Keller, W W Lac. The role of insulin and glucagon in the regulation of basal glucose production in the postabsorptive dog. The Journal of clinical investigation. vol 58. issue 6. 1977-01-25. PMID:993351. |
infusion of somatostatin alone caused the arterial levels of insulin and glucagon to drop rapidly by 72+/-6 and 81+/-8%, respectively. |
1977-01-25 |
2023-08-11 |
dog |
| A D Cherrington, J L Chiasson, J E Liljenquist, A S Jennings, U Keller, W W Lac. The role of insulin and glucagon in the regulation of basal glucose production in the postabsorptive dog. The Journal of clinical investigation. vol 58. issue 6. 1977-01-25. PMID:993351. |
somatostatin had no effect on glucose production when the changes in the pancreatic hormone levels which it normally induces were prevented by simultaneous intraportal infusion of both insulin and glucagon. |
1977-01-25 |
2023-08-11 |
dog |
| A D Cherrington, J L Chiasson, J E Liljenquist, A S Jennings, U Keller, W W Lac. The role of insulin and glucagon in the regulation of basal glucose production in the postabsorptive dog. The Journal of clinical investigation. vol 58. issue 6. 1977-01-25. PMID:993351. |
in conclusion, in the anesthetized dog fasted overnight; (a) basal glucagon is responsible for at least one-third of basal glucose production, (b) basal insulin prevents the increased glucose production which would result from the unrestrained action of glucagon, and (c) somatostatin has no acute effects on glucose turnover other than those it induces through perturbation of pancreatic hormone secretion. |
1977-01-25 |
2023-08-11 |
dog |
| J Osorio, J E Campillo, J G de los Arcos, I Pagés, E Rodríguez, M Marasco, F Melan. Inhibition of the glucose induced insulin release by somatostatin in the isolated perfused rat pancreas. Action of cyclic AMP, glucagon and glibenclamide. Revista espanola de fisiologia. vol 32. issue 3. 1977-01-03. PMID:185668. |
inhibition of the glucose induced insulin release by somatostatin in the isolated perfused rat pancreas. |
1977-01-03 |
2023-08-11 |
rat |
| J Osorio, J E Campillo, J G de los Arcos, I Pagés, E Rodríguez, M Marasco, F Melan. Inhibition of the glucose induced insulin release by somatostatin in the isolated perfused rat pancreas. Action of cyclic AMP, glucagon and glibenclamide. Revista espanola de fisiologia. vol 32. issue 3. 1977-01-03. PMID:185668. |
a complete blockage of the typical biphasic pattern of insulin release ocurred with somatostatin in the medium. |
1977-01-03 |
2023-08-11 |
rat |
| J Osorio, J E Campillo, J G de los Arcos, I Pagés, E Rodríguez, M Marasco, F Melan. Inhibition of the glucose induced insulin release by somatostatin in the isolated perfused rat pancreas. Action of cyclic AMP, glucagon and glibenclamide. Revista espanola de fisiologia. vol 32. issue 3. 1977-01-03. PMID:185668. |
the results suggest that the adenylcyclase dependent mechanisms of glucose-induced insulin release are involved in the inhibition of the glucose-induced insulin secretion by somatostatin. |
1977-01-03 |
2023-08-11 |
rat |
| R Sherwin, J Wahren, P Feli. Evanescent effects of hypo- and hyperglucagonemia on blood glucose homeostasis. Metabolism: clinical and experimental. vol 25. issue 11 Suppl 1. 1977-01-03. PMID:979638. |
despite on-going glucagon suppression by somatostatin, fasting hyperglycemia develops within 4-6 hr of insulin suppression, indicating that (1) basal glucagon secretion is not essential for the development of the diabetic state; and (2) insulin-deficiency (rather than altered glucagon secretion) is the dominant long-term factor determining glucose homeostasis in the diabetic. |
1977-01-03 |
2023-08-11 |
human |
| G F Bottazzo, R Lendru. Separate autoantibodies to human pancreatic glucagon and somatostatin cells. Lancet (London, England). vol 2. issue 7991. 1976-12-30. PMID:62113. |
a double immunofluorescence technique, with antisera to pancreatic glucagon, insulin, somatostatin, and human pancreatic polypeptide was used to show that 13 of the sera contained anitbodies reacting specifically with glucagon cells, while the other 4 reacted with somatostatin cells. |
1976-12-30 |
2023-08-11 |
human |
| P Schauder, C McIntosh, J Arends, R Arnold, H Frerichs, W Creutzfeld. Somatostatin and insulin release from isolated rat pancreatic islets stimulated by glucose. FEBS letters. vol 68. issue 2. 1976-12-30. PMID:789115. |
somatostatin and insulin release from isolated rat pancreatic islets stimulated by glucose. |
1976-12-30 |
2023-08-11 |
rat |
| H Nakabayashi, K Yoshimitsu, M Kishitani, M Ueda, M Kawat. [Effect of somatostatin on pancreatic endocrine--experiment by somatostatin infusion into the pancreaticoduodenal artery in dogs--(author's transl)]. Nihon Naibunpi Gakkai zasshi. vol 52. issue 3. 1976-12-01. PMID:786754. |
next, the effect of somatostatin on the glucose-induced insulin release from the pancreas was also evaluated. |
1976-12-01 |
2023-08-11 |
Not clear |
| H Nakabayashi, K Yoshimitsu, M Kishitani, M Ueda, M Kawat. [Effect of somatostatin on pancreatic endocrine--experiment by somatostatin infusion into the pancreaticoduodenal artery in dogs--(author's transl)]. Nihon Naibunpi Gakkai zasshi. vol 52. issue 3. 1976-12-01. PMID:786754. |
(2)during infusion of somatostatin at a speed of 1.25 mug/minute, insulin response to glucose injected into the pancreaticoduodenal artery in a small dose, as well as having no effect on the plasma glucose level in systemic circulation, was also significantly inhibited. |
1976-12-01 |
2023-08-11 |
Not clear |
| D E Johnson, J L Torrence, R P Elde, G E Bauer, B D Noe, D J Fletche. Immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (Lophius americanus) and the channel catfish (Ictalurus punctata) (1) (2). The American journal of anatomy. vol 147. issue 1. 1976-12-01. PMID:788493. |
immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (lophius americanus) and the channel catfish (ictalurus punctata) (1) (2). |
1976-12-01 |
2023-08-11 |
Not clear |
| D E Johnson, J L Torrence, R P Elde, G E Bauer, B D Noe, D J Fletche. Immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (Lophius americanus) and the channel catfish (Ictalurus punctata) (1) (2). The American journal of anatomy. vol 147. issue 1. 1976-12-01. PMID:788493. |
somatostatin, insulin and glucagon were localized in the principal islets of the anglerfish (lophius americanus) and the channel catfish (ictalurus punctata) by means of the unlabeled antibody-peroxidase-antiperoxidase immunocytochemical method. |
1976-12-01 |
2023-08-11 |
Not clear |
| D E Johnson, J L Torrence, R P Elde, G E Bauer, B D Noe, D J Fletche. Immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (Lophius americanus) and the channel catfish (Ictalurus punctata) (1) (2). The American journal of anatomy. vol 147. issue 1. 1976-12-01. PMID:788493. |
both species showed a similar ratio of positive cells 9:6:4 (insulin:somatostatin:glucagon), but the interrelations of the three cell types differed between species. |
1976-12-01 |
2023-08-11 |
Not clear |