| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E L Lie. Effect of somatostatin and a glucagon-specific analog on glucose homeostasis during arginine infusion. Metabolism: clinical and experimental. vol 27. issue 9. 1978-10-25. PMID:682972. |
infusion of somatostatin resulted in supression of both arginine-induced insulin and arginine-induced glucagon release, and marked hyperglycemia ensued. |
1978-10-25 |
2023-08-11 |
rat |
| G S Tannenbaum, J Epelbaum, E Colle, P Brazeau, J B Marti. Dissociation of effects of somatostatin antiserum on growth hormone and insulin secretion. Metabolism: clinical and experimental. vol 27. issue 9 Suppl 1. 1978-10-25. PMID:682990. |
dissociation of effects of somatostatin antiserum on growth hormone and insulin secretion. |
1978-10-25 |
2023-08-11 |
Not clear |
| D H Coy, C Meyers, A Arimura, A V Schally, T W Reddin. Observations on the growth hormone, insulin, and glucagon release-inhibiting activities of somatostatin analogues. Metabolism: clinical and experimental. vol 27. issue 9 Suppl 1. 1978-10-25. PMID:683009. |
observations on the growth hormone, insulin, and glucagon release-inhibiting activities of somatostatin analogues. |
1978-10-25 |
2023-08-11 |
Not clear |
| R S Sherwin, W V Tamborlane, R Hendler, P Feli. Diabetogenic effects of somatostatin in maturity-onset diabetes and normal man: primacy of insulin deficiency rather than glucagon excess in the pathogenesis of diabetes. Metabolism: clinical and experimental. vol 27. issue 9 Suppl 1. 1978-10-25. PMID:683012. |
diabetogenic effects of somatostatin in maturity-onset diabetes and normal man: primacy of insulin deficiency rather than glucagon excess in the pathogenesis of diabetes. |
1978-10-25 |
2023-08-11 |
Not clear |
| W K Waldhäusl, P Bratusch-Marrain, B Loebenstei. Diabetogenic action of somatostatin in healthy subjects: effect of amino acids and somatostatin upon blood glucose, serum insulin, and glucagon. Metabolism: clinical and experimental. vol 27. issue 9 Suppl 1. 1978-10-25. PMID:683013. |
diabetogenic action of somatostatin in healthy subjects: effect of amino acids and somatostatin upon blood glucose, serum insulin, and glucagon. |
1978-10-25 |
2023-08-11 |
human |
| Y Harano, H Hidaka, K Takatsuki, S Ohgaku, M Haneda, S Motoi, K Kawagoe, Y Shigeta, H Ab. Glucose, insulin, and somatostatin infusion for the determination of insulin sensitivity in vivo. Metabolism: clinical and experimental. vol 27. issue 9 Suppl 1. 1978-10-25. PMID:683015. |
glucose, insulin, and somatostatin infusion for the determination of insulin sensitivity in vivo. |
1978-10-25 |
2023-08-11 |
Not clear |
| M G Piccard. [Some physiopathological aspects of therapy of diabetic ketoacidosis: treatment with insulin and somatostatin]. La Clinica terapeutica. vol 85. issue 5. 1978-10-18. PMID:98256. |
[some physiopathological aspects of therapy of diabetic ketoacidosis: treatment with insulin and somatostatin]. |
1978-10-18 |
2023-08-11 |
Not clear |
| P Schauder, C McIntosh, B Schindler, U Panten, H Frerich. Comparison of alpha-ketoisocaproic acid and glucose in rats: effects on insulin and somatostatin release and on islet cAMP content. Molecular and cellular endocrinology. vol 11. issue 1. 1978-10-18. PMID:210060. |
comparison of alpha-ketoisocaproic acid and glucose in rats: effects on insulin and somatostatin release and on islet camp content. |
1978-10-18 |
2023-08-11 |
rat |
| T Kann. Physiology of paraneurons. Archivum histologicum Japonicum = Nihon soshikigaku kiroku. vol 40 Suppl. 1978-09-30. PMID:354576. |
somatostatin in most cases and insulin in a special case may act locally on the adjacent target cells, and such a mode of transmission may come into the category of paracrine secretion. |
1978-09-30 |
2023-08-11 |
Not clear |
| A Kaneto, H Kajinuma, T Kaneko, K Kosak. Effect of phentolamine on the somatostatin-induced inhibition of glucagon and insulin secretion. Metabolism: clinical and experimental. vol 27. issue 8. 1978-09-25. PMID:209286. |
somatostatin infused into the pancreatic artery at a dose of 50 ng/kg/min for 10 min caused significant decreases in blood flow and plasma basal concentrations of both glucagon and insulin in the cranial pancreaticoduodenal vein, resulting in a profound decline of bihormonal output during the infusion. |
1978-09-25 |
2023-08-11 |
Not clear |
| A Kaneto, H Kajinuma, T Kaneko, K Kosak. Effect of phentolamine on the somatostatin-induced inhibition of glucagon and insulin secretion. Metabolism: clinical and experimental. vol 27. issue 8. 1978-09-25. PMID:209286. |
these results indicate that alpha-adrenergic receptor mechanisms do not play a major role in the inhibition of islet glucagon and insulin secretion by somatostatin. |
1978-09-25 |
2023-08-11 |
Not clear |
| K Murakami, H Taniguchi, M Hasegawa, T Kobayashi, Y Wantanabe, M Seki, A Tsutou, S Bab. Physiological significance of somatostatin in insulin release. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 10. issue 3. 1978-09-15. PMID:352891. |
physiological significance of somatostatin in insulin release. |
1978-09-15 |
2023-08-11 |
Not clear |
| G I Shulman, J E Liljenquist, P E Williams, W W Lacy, A D Cherringto. Glucose disposal during insulinopenia in somatostatin-treated dogs. The roles of glucose and glucagon. The Journal of clinical investigation. vol 62. issue 2. 1978-09-15. PMID:670404. |
to accomplish this, glucose was infused into conscious dogs whose basal insulin and glucagon secretion had been replaced by exogenous intraportal insulin and glucagon infusion after somatostatin inhibition of endogenous pancreatic hormone release. |
1978-09-15 |
2023-08-11 |
Not clear |
| D F Veber, F W Holly, W J Paleveda, R F Nutt, S J Bergstrand, M Torchiana, M S Glitzer, R Saperstein, R Hirschman. Conformationally restricted bicyclic analogs of somatostatin. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 6. 1978-09-01. PMID:208068. |
the synthesis of the novel bicyclic analogs of somatostatin and the effects of these on the inhibition of secretion of insulin, glucagon, growth hormone, and gastric acid are described. |
1978-09-01 |
2023-08-11 |
Not clear |
| M Laburthe, M Rousset, C Boissard, G Chevalier, A Zweibaum, G Rosseli. Vasoactive intestinal peptide: a potent stimulator of adenosine 3':5'-cyclic monophosphate accumulation in gut carcinoma cell lines in culture. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 6. 1978-09-01. PMID:208077. |
the other peptides tested at 10(-7) m, such as insulin, glucagon, bovine pancreatic polypeptide, somatostatin, octapeptide of cholecystokinin, neurotensin, and substance p, did not stimulate camp accumulation. |
1978-09-01 |
2023-08-11 |
human |
| B H Hirst, J D Reed, B Shaw, D H Coy, A V Schall. Quantitation of somatostatin inhibition of insulin-stimulated gastric acid and pepsin secretion in the cat. Acta hepato-gastroenterologica. vol 25. issue 3. 1978-09-01. PMID:352081. |
somatostatin 0.5-5 microgram kg-1h-1 produced a dose dependent reduction of both acid and pepsin secretions stimulated by insulin 0.2 u kg-1h-1. |
1978-09-01 |
2023-08-11 |
cat |
| B H Hirst, J D Reed, B Shaw, D H Coy, A V Schall. Quantitation of somatostatin inhibition of insulin-stimulated gastric acid and pepsin secretion in the cat. Acta hepato-gastroenterologica. vol 25. issue 3. 1978-09-01. PMID:352081. |
the results indicate that somatostatin is a more potent inhibitor of insulin 0.2 u kg-1h-1 stimulated acid secretion than pentagastrin 8 microgram kg-1h-1 stimulated acid secretion, but is a more potent inhibitor of pentagastrin--than insulin--stimulated pepsin secretion. |
1978-09-01 |
2023-08-11 |
cat |
| B H Hirst, J D Reed, B Shaw, D H Coy, A V Schall. Quantitation of somatostatin inhibition of insulin-stimulated gastric acid and pepsin secretion in the cat. Acta hepato-gastroenterologica. vol 25. issue 3. 1978-09-01. PMID:352081. |
as insulin stimulates less acid and more pepsin secretion than pentagastrin, the differences in sensitivities to somatostatin of these secretions produced by the two stimulants is thought to be a result of the different absolute amounts of secretion produced by the stimulants. |
1978-09-01 |
2023-08-11 |
cat |
| W P Tormey, W G Davis, A S Darrag. Nocturnal ulcer pain associated with slow-wave sleep. Lancet (London, England). vol 1. issue 8078. 1978-08-28. PMID:78101. |
it is also associated with inhibition of gastrointestinal somatostatin, causing a release of gastrin and insulin. |
1978-08-28 |
2023-08-11 |
Not clear |
| U Junge, W Creutzfeld. Hepatotrophic effects of pancreatic and gastrointestinal hormones in the rat in vivo and in vitro. Ciba Foundation symposium. issue 55. 1978-08-28. PMID:248003. |
in vitro, insulin, glucagon and somatostatin synergistically stimulated the specific thymidine uptake in seven-day-old maintenance cultures of rat hepatocytes. |
1978-08-28 |
2023-08-11 |
rat |