| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P O Andersson, J Holst, J Järhul. Effects of adrenergic blockade on the release of insulin, glucagon and somatostatin from the pancreas in response to splanchnic nerve stimulation in cats. Acta physiologica Scandinavica. vol 116. issue 4. 1983-06-23. PMID:6133409. |
in control experiments splanchnic nerve stimulation caused a marked rise in plasma glucose and glucagon concentrations and a marked fall in insulin but somatostatin was unaffected. |
1983-06-23 |
2023-08-12 |
Not clear |
| P O Andersson, J Holst, J Järhul. Effects of adrenergic blockade on the release of insulin, glucagon and somatostatin from the pancreas in response to splanchnic nerve stimulation in cats. Acta physiologica Scandinavica. vol 116. issue 4. 1983-06-23. PMID:6133409. |
it is concluded that insulin release from the pancreas and glucose release from the liver is controlled by adrenergic mechanisms whereas pancreatic glucagon and somatostatin secretion is relatively insensitive to splanchnic nerve stimulation in cats. |
1983-06-23 |
2023-08-12 |
Not clear |
| W W Lautt, D J Légaré, E S Marten. A possible role for somatostatin in depression of insulin and glucagon levels during hemorrhage. Canadian journal of physiology and pharmacology. vol 61. issue 3. 1983-06-17. PMID:6132675. |
a possible role for somatostatin in depression of insulin and glucagon levels during hemorrhage. |
1983-06-17 |
2023-08-12 |
cat |
| W W Lautt, D J Légaré, E S Marten. A possible role for somatostatin in depression of insulin and glucagon levels during hemorrhage. Canadian journal of physiology and pharmacology. vol 61. issue 3. 1983-06-17. PMID:6132675. |
the hypothesis that depression of insulin and glucagon levels during rapid, acute hemorrhage is controlled by somatostatin was supported by hormonal changes measured in the cat. |
1983-06-17 |
2023-08-12 |
cat |
| W W Lautt, D J Légaré, E S Marten. A possible role for somatostatin in depression of insulin and glucagon levels during hemorrhage. Canadian journal of physiology and pharmacology. vol 61. issue 3. 1983-06-17. PMID:6132675. |
by 5 min of hemorrhage to 50 mmhg (1 mmhg = 133.322 pa) arterial blood pressure, insulin and glucagon were severely depressed and somatostatin levels rose to 232% of basal levels. |
1983-06-17 |
2023-08-12 |
cat |
| W W Lautt, D J Légaré, E S Marten. A possible role for somatostatin in depression of insulin and glucagon levels during hemorrhage. Canadian journal of physiology and pharmacology. vol 61. issue 3. 1983-06-17. PMID:6132675. |
following return of the blood, somatostatin levels remained high and insulin and glucagon suppression was maintained. |
1983-06-17 |
2023-08-12 |
cat |
| D Scholz, P O Schwill. Effects of acutely infused pentagastrin and somatostatin on intestinal calcium absorption in humans. Mineral and electrolyte metabolism. vol 7. issue 2. 1983-06-17. PMID:6133213. |
to exclude the influence of hormones like insulin, glucagon and calcitonin stimulated by pg, somatostatin was infused in additional trials. |
1983-06-17 |
2023-08-12 |
human |
| K Tanigawa, H Kuzuya, M Okamoto, H Imur. Effects of insulin secretagogues and inhibitors on phospholipid metabolism in Langerhans' islets of rat pancreas. Biochemical and biophysical research communications. vol 112. issue 2. 1983-06-17. PMID:6303318. |
furthermore, the potent inhibitor of insulin release, somatostatin did not alter phospholipid metabolism. |
1983-06-17 |
2023-08-12 |
rat |
| J P Blayac, E R Trimble, G Ribes, M M Loubatières-Marian. [Effect of chronic administration of an acylamino alcoyl derivative of benzoic acid, HB 699, on the pancreatic polypeptide secretion in the dog]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 176. issue 5. 1983-06-10. PMID:6220772. |
this agent induced an increase in fasting plasma levels of pancreatic polypeptide, without modifying blood glucose, insulin, glucagon and somatostatin levels. |
1983-06-10 |
2023-08-12 |
dog |
| G Boden, A Naji, C F Barker, V June, F M Matschinsk. Effect of spontaneous diabetes on hormone release in BB/Phi rats: comparison between the isolated perfused pancreas/stomach/duodenum/spleen and the isolated perfused pancreas. Endocrinology. vol 112. issue 5. 1983-05-27. PMID:6131815. |
in the psds preparation, diabetes reduced total integrated insulin output by 97% (from 1146 +/- 198 to 40 +/- 24 ng/65 min, p less than 0.001), and glucagon output by about 50% (from 51.6 +/- 13.1 to 24.0 +/- 3.7 ng/65 min, p less than 0.05), whereas somatostatin output did not change (105.5 +/- 48.1 to 110.1 +/- 36.9 ng/65 min). |
1983-05-27 |
2023-08-12 |
rat |
| G Boden, A Naji, C F Barker, V June, F M Matschinsk. Effect of spontaneous diabetes on hormone release in BB/Phi rats: comparison between the isolated perfused pancreas/stomach/duodenum/spleen and the isolated perfused pancreas. Endocrinology. vol 112. issue 5. 1983-05-27. PMID:6131815. |
in the diabetic bb/phi rats, pancreatic glucagon and insulin release was virtually abolished while glucagon secretion from the intestinal tract increased and somatostatin secretion decreased. |
1983-05-27 |
2023-08-12 |
rat |
| Y Stefan, S Grasso, A Perrelet, L Orc. A quantitative immunofluorescent study of the endocrine cell populations in the developing human pancreas. Diabetes. vol 32. issue 4. 1983-05-27. PMID:6131849. |
this cell population decreases and disappears in later stages and is replaced by the adult type glucagon/glicentin immunoreactive cell; (2) the pancreatic polypeptide-rich region shows a lower relative endocrine cell content as compared with the glucagon-rich region and its islets appear smaller; (3) in the total pancreas, the relative (volume density) and absolute (microliter) insulin cell content increases regularly with age, while the relative volume of glucagon cells peaks in fetal life (wk 17--20) to decrease in infants, although remaining at higher levels than in adults; the relative and absolute volumes of somatostatin cells are elevated in fetal and infant stages studied where they represent the second most abundant cell type, while pancreatic polypeptide cells appear to least abundant cells during prenatal and infant life. |
1983-05-27 |
2023-08-12 |
human |
| R L Sorenson, L H Grouse, R P Eld. Cysteamine blocks somatostatin secretion without altering the course of insulin or glucagon release. A new model for the study of islet function. Diabetes. vol 32. issue 4. 1983-05-27. PMID:6131850. |
cysteamine blocks somatostatin secretion without altering the course of insulin or glucagon release. |
1983-05-27 |
2023-08-12 |
rat |
| R L Sorenson, L H Grouse, R P Eld. Cysteamine blocks somatostatin secretion without altering the course of insulin or glucagon release. A new model for the study of islet function. Diabetes. vol 32. issue 4. 1983-05-27. PMID:6131850. |
cysteamine (300 mg/kg) administered subcutaneously depletes pancreatic somatostatin to 36% of control levels, but does not alter pancreatic insulin or glucagon content. |
1983-05-27 |
2023-08-12 |
rat |
| W Y Fujimoto, S Kawazu, M Ikeuchi, Y Kanazaw. In vitro paracrine regulation of islet B-cell function by A and D cells. Life sciences. vol 32. issue 16. 1983-05-27. PMID:6132317. |
thus, although exogenously added glucagon stimulates insulin secretion, the effect of endogenously released glucagon upon islet b cells is a restraining one which may be mediated through an effect upon d cells and their release of endogenous somatostatin. |
1983-05-27 |
2023-08-12 |
rat |
| R D Milner, F Dinsdale, P K Wirdnam, F A Van Assch. Pancreatic endocrine cell fractions in erythroblastosis fetalis. Diabetes. vol 32. issue 4. 1983-05-27. PMID:6339304. |
pancreatic sections from 21 cases of rhesus disease and 20 control newborn infants of 30--40-wk gestational age were stained by the immunoperoxidase method for insulin, glucagon, somatostatin, and pancreatic polypeptide (pp). |
1983-05-27 |
2023-08-12 |
Not clear |
| F Caviezel, A Albertini, D Spotti, G Pozz. On the inhibitory effects of somatostatin on arginine-induced insulin and growth hormone secretion in man: influence of aminophylline. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 15. issue 1. 1983-05-05. PMID:6131858. |
on the inhibitory effects of somatostatin on arginine-induced insulin and growth hormone secretion in man: influence of aminophylline. |
1983-05-05 |
2023-08-12 |
Not clear |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
the size and area of jib islets were unchanged from controls as was the distribution of insulin, glucagon, somatostatin and pancreatic polypeptide. |
1983-05-05 |
2023-08-12 |
rat |
| P Masiello, C B Wollheim, B Blondel, A E Renol. Studies in vivo and in vitro on chemically-induced primary islet cell tumours and non-tumour endocrine pancreatic tissue. Diabetologia. vol 24. issue 1. 1983-04-21. PMID:6131005. |
the tumours were rich in immunoreactive insulin and somatostatin, poor in glucagon. |
1983-04-21 |
2023-08-12 |
rat |
| P Masiello, C B Wollheim, B Blondel, A E Renol. Studies in vivo and in vitro on chemically-induced primary islet cell tumours and non-tumour endocrine pancreatic tissue. Diabetologia. vol 24. issue 1. 1983-04-21. PMID:6131005. |
non-tumour pancreatic tissue or isolated islets contained 10% or less of the corresponding normal amounts of insulin whereas the islet content of somatostatin was unchanged and that of glucagon increased. |
1983-04-21 |
2023-08-12 |
rat |