| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Murakami, H Taniguchi, M Tamagawa, K Ejiri, S Bab. Modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between A, B and D cells in rat pancreatic islets. Endocrinologia japonica. vol 29. issue 5. 1983-07-15. PMID:6133744. |
modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between a, b and d cells in rat pancreatic islets. |
1983-07-15 |
2023-08-12 |
rat |
| K Murakami, H Taniguchi, M Tamagawa, K Ejiri, S Bab. Modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between A, B and D cells in rat pancreatic islets. Endocrinologia japonica. vol 29. issue 5. 1983-07-15. PMID:6133744. |
in order to understand the physiological role of endogenous insulin or glucagon in somatostatin release, isolated rat pancreatic islets were treated with antiinsulin or antiglucagon antiserum in the presence of physiological amounts of glucose. |
1983-07-15 |
2023-08-12 |
rat |
| K Murakami, H Taniguchi, M Tamagawa, K Ejiri, S Bab. Modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between A, B and D cells in rat pancreatic islets. Endocrinologia japonica. vol 29. issue 5. 1983-07-15. PMID:6133744. |
the release of somatostatin was unchanged by treatment with antiinsulin antiserum which neutralized insulin released by 3.3, 8.3 and 16.7 mm of glucose. |
1983-07-15 |
2023-08-12 |
rat |
| J Simon, M P Duboi. Subtotal pancreatectomy in the chicken: evidence of a diabetic state and effect on the somatostatin cells of the digestive tract. Diabete & metabolisme. vol 9. issue 1. 1983-07-15. PMID:6133785. |
the eventual appearance of an extra-pancreatic source of insulin and the effect of pancreatectomy on somatostatin containing cells of the intestine were also investigated. |
1983-07-15 |
2023-08-12 |
chicken |
| J Simon, M P Duboi. Subtotal pancreatectomy in the chicken: evidence of a diabetic state and effect on the somatostatin cells of the digestive tract. Diabete & metabolisme. vol 9. issue 1. 1983-07-15. PMID:6133785. |
the size of the somatostatin cells from the gizzard-duodenum junction was negatively related to the magnitude of the glucose-induced insulin release, which suggests an increase in somatostatin cell activity in true insulin-deficient depancreatized chickens as observed in insulin deficient diabetic mammals. |
1983-07-15 |
2023-08-12 |
chicken |
| H A El Munshid, J J Holst, I Lundquist, G Lundqvist, O B Schaffalitzky De Muckadell, R Håkanso. Role of the kidneys in elimination of glucagon, insulin, secretin and somatostatin in the rat. Acta physiologica Scandinavica. vol 117. issue 1. 1983-07-15. PMID:6134426. |
role of the kidneys in elimination of glucagon, insulin, secretin and somatostatin in the rat. |
1983-07-15 |
2023-08-12 |
rat |
| H A El Munshid, J J Holst, I Lundquist, G Lundqvist, O B Schaffalitzky De Muckadell, R Håkanso. Role of the kidneys in elimination of glucagon, insulin, secretin and somatostatin in the rat. Acta physiologica Scandinavica. vol 117. issue 1. 1983-07-15. PMID:6134426. |
insulin and somatostatin levels were significantly elevated 48 hours after nephrectomy, but not after ureteral ligation, indicating partial uptake from peritubular capillaries. |
1983-07-15 |
2023-08-12 |
rat |
| b' C G Ostenson, V Grill, A Nyl\\xc3\\xa9n, S Efendi\\xc4\\x8. Modulation by IBMX, fasting and experimental diabetes of glibenclamide-induced islet hormone release from the perfused rat pancreas. Diabete & metabolisme. vol 9. issue 1. 1983-07-15. PMID:6189748.' |
the impact of increased c-amp levels, short-term fasting as well as experimental diabetes on glibenclamide-induced secretion of somatostatin, insulin and glucagon was studied in the isolated perfused rat pancreas. |
1983-07-15 |
2023-08-12 |
rat |
| b' C G Ostenson, V Grill, A Nyl\\xc3\\xa9n, S Efendi\\xc4\\x8. Modulation by IBMX, fasting and experimental diabetes of glibenclamide-induced islet hormone release from the perfused rat pancreas. Diabete & metabolisme. vol 9. issue 1. 1983-07-15. PMID:6189748.' |
dose-response curves revealed that 1 microgram/ml of glibenclamide (in the presence of 3.3 mmol/l of glucose) induced maximal stimulation of insulin and near maximal stimulation of somatostatin release, but did not significantly affect glucagon release. |
1983-07-15 |
2023-08-12 |
rat |
| b' C G Ostenson, V Grill, A Nyl\\xc3\\xa9n, S Efendi\\xc4\\x8. Modulation by IBMX, fasting and experimental diabetes of glibenclamide-induced islet hormone release from the perfused rat pancreas. Diabete & metabolisme. vol 9. issue 1. 1983-07-15. PMID:6189748.' |
fasting the rats for 24 h significantly suppressed the insulin and glucagon responses to glibenclamide while the concomitant somatostatin response was slightly enhanced. |
1983-07-15 |
2023-08-12 |
rat |
| I B Brekke, J Alumets, F Sundle. The duct-ligated pancreas transplant and its effect on the islet cellular composition of the host pancreas. A morphometric analysis. Cell and tissue research. vol 231. issue 1. 1983-07-15. PMID:6342807. |
twenty weeks after pancreas transplantation, the volume fractions of insulin, glucagon, somatostatin and pancreatic polypeptide cells in the graft islets did not differ from those of the normal control pancreas. |
1983-07-15 |
2023-08-12 |
rat |
| D R Owens, M K Jones, A J Birtwell, I R Jones, T M Hayes, L G Hedin. The clinical pharmacology of human insulin (Novo) in normal subjects. Diabetes care. vol 6 Suppl 1. 1983-07-08. PMID:6133710. |
the plasma glucose, c-peptide, and insulin (immunoreactive) responses to human insulin and porcine insulin were identical in the studies with and without somatostatin. |
1983-07-08 |
2023-08-12 |
human |
| D R Owens, M K Jones, A J Birtwell, I R Jones, T M Hayes, L G Hedin. The clinical pharmacology of human insulin (Novo) in normal subjects. Diabetes care. vol 6 Suppl 1. 1983-07-08. PMID:6133710. |
although the incremental plasma insulin values achieved with the two insulins were similar in the two studies, the hypoglycemic effect was accentuated in the presence of somatostatin, with a delayed recovery toward normoglycemia. |
1983-07-08 |
2023-08-12 |
human |
| S Kadowaki, T Taminato, T Chiba, M Nozawa, T Fujita, A W Norma. Effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration. Endocrinology. vol 112. issue 6. 1983-07-08. PMID:6133743. |
effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration. |
1983-07-08 |
2023-08-12 |
rat |
| S Kadowaki, T Taminato, T Chiba, M Nozawa, T Fujita, A W Norma. Effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration. Endocrinology. vol 112. issue 6. 1983-07-08. PMID:6133743. |
the effects of tolbutamide on insulin, glucagon, and somatostatin secretion were investigated in the isolated perfused pancreas from normal and diabetic rats under low (30 mg/dl), normal (100 mg/dl), and high (300 mg/dl) glucose conditions. |
1983-07-08 |
2023-08-12 |
rat |
| S Kadowaki, T Taminato, T Chiba, M Nozawa, T Fujita, A W Norma. Effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration. Endocrinology. vol 112. issue 6. 1983-07-08. PMID:6133743. |
in the diabetic rat pancreas, insulin release was diminished and tolbutamide-induced somatostatin release was enhanced with increasing glucose concentrations. |
1983-07-08 |
2023-08-12 |
rat |
| F Caviezel, R Mangil. Calcitonin and insulin secretion in normal man: study with somatostatin and calcium. Acta diabetologica latina. vol 20. issue 1. 1983-07-08. PMID:6134414. |
calcitonin and insulin secretion in normal man: study with somatostatin and calcium. |
1983-07-08 |
2023-08-12 |
human |
| F Caviezel, R Mangil. Calcitonin and insulin secretion in normal man: study with somatostatin and calcium. Acta diabetologica latina. vol 20. issue 1. 1983-07-08. PMID:6134414. |
an increase in extracellular calcium concentration abolishes somatostatin-induced inhibition of insulin release from rat pancreas in vitro; since calcium fails to have a similar effect in vivo, and calcitonin (ct) is capable of inhibiting insulin release, we investigated calcium-stimulated ct secretion during somatostatin administration in normal human males. |
1983-07-08 |
2023-08-12 |
human |
| F Caviezel, R Mangil. Calcitonin and insulin secretion in normal man: study with somatostatin and calcium. Acta diabetologica latina. vol 20. issue 1. 1983-07-08. PMID:6134414. |
thus, we suggest that calcium-induced ct release in vivo may counteract the reversal effect of calcium on the suppressor activity of somatostatin on insulin secretion as shown in vitro. |
1983-07-08 |
2023-08-12 |
human |
| K E Sussman, H B Pollard, J W Leitner, R Nesher, J Adler, E Ceras. Granule fusion and fission (discharge) are biochemically dissociable events of exocytotic hormone release. Transactions of the Association of American Physicians. vol 95. 1983-07-08. PMID:6190296. |
as an index of fusion, we followed the recruitment of granule-bound somatostatin receptors to the islet surface, an event which accompanies secretion vesicle migration and insulin secretion. |
1983-07-08 |
2023-08-12 |
Not clear |