| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Rahier, R M Goebbels, J C Henqui. Cellular composition of the human diabetic pancreas. Diabetologia. vol 24. issue 5. 1983-09-20. PMID:6347784. |
insulin, glucagon, somatostatin and pancreatic polypeptide cells were stained by immunoperoxidase techniques and quantitated morphometrically in sections of pancreases obtained from eight control subjects, four type 1 (insulin-dependent) and eight type 2 (non-insulin-dependent) diabetic patients. |
1983-09-20 |
2023-08-12 |
human |
| D J Evans, R G Hoffmann, R K Kalkhoff, A H Kisseba. Relationship of androgenic activity to body fat topography, fat cell morphology, and metabolic aberrations in premenopausal women. The Journal of clinical endocrinology and metabolism. vol 57. issue 2. 1983-08-26. PMID:6345569. |
increasing androgenicity, as reflected by a decrease in plasma sex hormone-binding globulin capacity and an increase in the percentage of free testosterone, was accompanied by 1) increasing whr, this relationship being independent of and additive to that of obesity level; 2) increasing size of abdominal, but not femoral, adipocytes; 3) increasing plasma glucose and insulin levels, both basally and in response to oral glucose loading; and 4) diminished in vivo insulin sensitivity, as revealed by increasing steady state plasma glucose levels at comparable plasma insulin levels, attained by the infusion of somatostatin, insulin, and glucose. |
1983-08-26 |
2023-08-12 |
Not clear |
| K I Bickerstaff, C A Garberoglio, A L Baker, A R Mooss. Hormonal control of biliary lipid secretion in dogs. Annals of surgery. vol 198. issue 2. 1983-08-17. PMID:6135393. |
the results show that 1) the biliary secretion of cholesterol and phospholipid is increased by pharmacologic doses of somatostatin and 2) physiologic doses of glucagon, but not insulin , suppress the biliary secretion of cholesterol and phospholipid. |
1983-08-17 |
2023-08-12 |
Not clear |
| C Gebhardt, M Stolte, P O Schwille, H Zirngibl, W Engelhard. Experimental studies on pancreatic duct occlusion with prolamine. Hormone and metabolic research. Supplement series. issue 13. 1983-08-17. PMID:6345328. |
the basal jugular vein insulin shows no difference to that of the control group, but nevertheless the mean whole pancreas hormone content is reduced for insulin and somatostatin, but not for glucagon. |
1983-08-17 |
2023-08-12 |
Not clear |
| H Sasaki, M Nagulesparan, A Dubois, B Vasquez, E Straus, M L Sievers, R H Unge. Inhibitory effect of intragastric glucose on gastric acid secretion and gastric emptying of liquids in man. Role of endogenous somatostatin, gastrin, and insulin. Digestive diseases and sciences. vol 28. issue 6. 1983-08-11. PMID:6134603. |
role of endogenous somatostatin, gastrin, and insulin. |
1983-08-11 |
2023-08-12 |
human |
| Kawai, R H Unge. Effects of gamma-aminobutyric acid on insulin, glucagon, and somatostatin release from isolated perfused dog pancreas. Endocrinology. vol 113. issue 1. 1983-08-11. PMID:6134611. |
effects of gamma-aminobutyric acid on insulin, glucagon, and somatostatin release from isolated perfused dog pancreas. |
1983-08-11 |
2023-08-12 |
dog |
| Kawai, R H Unge. Effects of gamma-aminobutyric acid on insulin, glucagon, and somatostatin release from isolated perfused dog pancreas. Endocrinology. vol 113. issue 1. 1983-08-11. PMID:6134611. |
the effects of gamma-aminobutyric acid (gaba) on the secretion of insulin, glucagon, and somatostatin were studied in the isolated dog pancreas. |
1983-08-11 |
2023-08-12 |
dog |
| G Pozza, J Traeger, J M Dubernard, A Secchi, A E Pontiroli, E Bosi, M C Malik, A Ruitton, N Blan. Endocrine responses of type 1 (insulin-dependent) diabetic patients following successful pancreas transplantation. Diabetologia. vol 24. issue 4. 1983-08-11. PMID:6134651. |
somatostatin was less effective in diabetic patients than in control subjects in suppressing insulin and glucagon release. |
1983-08-11 |
2023-08-12 |
human |
| S Bonner-Weir, D F Trent, G C Wei. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. The Journal of clinical investigation. vol 71. issue 6. 1983-08-11. PMID:6134752. |
there were comparable increases in the remnant content of insulin, glucagon, and somatostatin. |
1983-08-11 |
2023-08-12 |
rat |
| J M Miles, M W Haymond, S L Nissen, J E Geric. Effects of free fatty acid availability, glucagon excess, and insulin deficiency on ketone body production in postabsorptive man. The Journal of clinical investigation. vol 71. issue 6. 1983-08-11. PMID:6134753. |
to determine whether an increase in ffa availability would augment kb production in the absence of insulin deficiency and glucagon excess, plasma insulin and glucagon were maintained at basal concentrations by infusion of somatostatin and exogenous insulin and glucagon, and plasma ffa were increased from 0.32 +/- 0.06 to 1.4 +/- 0.1 mm by a 2.5-h-infusion of a triglyceride emulsion plus heparin. |
1983-08-11 |
2023-08-12 |
Not clear |
| M Chaudhuri, J L Sartin, R C Adelma. A role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. Journal of gerontology. vol 38. issue 4. 1983-08-11. PMID:6134768. |
a role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. |
1983-08-11 |
2023-08-12 |
rat |
| M Chaudhuri, J L Sartin, R C Adelma. A role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. Journal of gerontology. vol 38. issue 4. 1983-08-11. PMID:6134768. |
the purpose of this study was to investigate a possible contribution by somatostatin to the impairment in glucose-stimulated secretion of insulin during aging. |
1983-08-11 |
2023-08-12 |
rat |
| M Chaudhuri, J L Sartin, R C Adelma. A role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. Journal of gerontology. vol 38. issue 4. 1983-08-11. PMID:6134768. |
concentrations of insulin, glucagon, and somatostatin were determined by radioimmunoassay. |
1983-08-11 |
2023-08-12 |
rat |
| M Chaudhuri, J L Sartin, R C Adelma. A role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. Journal of gerontology. vol 38. issue 4. 1983-08-11. PMID:6134768. |
the impairment of glucose-stimulated secretion of insulin which characterizes islets isolated from aged rats may be overcome by treatment of islets with antibodies to somatostatin. |
1983-08-11 |
2023-08-12 |
rat |
| M Chaudhuri, J L Sartin, R C Adelma. A role for somatostatin in the impaired insulin secretory response to glucose by islets from aging rats. Journal of gerontology. vol 38. issue 4. 1983-08-11. PMID:6134768. |
enhanced availability and/or effectiveness of endogenous pancreatic somatostatin during aging may be responsible for the modified pattern of glucose-stimulated secretion of insulin. |
1983-08-11 |
2023-08-12 |
rat |
| M Fried, K Gyr, C Beglinger, W Schlegel, U Grötzinger, G A Stalder, L Varg. [Addition of albumin to solutions of cholecystokinin (CCK)--effect on pancreatic secretion, plasma CCK level and release of pancreatic polypeptide (PP)]. Zeitschrift fur Gastroenterologie. vol 21. issue 3. 1983-08-11. PMID:6868720. |
dissolving basic peptides such as insulin, secretin, and somatostatin in albumin-containing solutions increases the biologic potency. |
1983-08-11 |
2023-08-12 |
Not clear |
| C L Potter, I G Sipes, D H Russel. Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration. Toxicology and applied pharmacology. vol 69. issue 1. 1983-07-29. PMID:6134353. |
the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) treatment on body temperature and serum and tissue levels of thyroid hormones, glucose, glucagon, insulin, and somatostatin were investigated. |
1983-07-29 |
2023-08-12 |
rat |
| A J Vander, W Victery, C Germain, D Hollowa. Insulin is a physiological inhibitor of urinary zinc excretion in anesthetized dogs. The American journal of physiology. vol 244. issue 6. 1983-07-29. PMID:6134471. |
infusion of insulin (30 mu x kg-1 x min-1) along with the somatostatin maintained plasma insulin constant and completely eliminated the somatostatin-induced hyperzincuria; indeed, a small decrease in zinc excretion invariably occurred. |
1983-07-29 |
2023-08-12 |
Not clear |
| A D Cherrington, W W Lacy, P E Williams, K E Steine. Failure of somatostatin to modify effect of glucagon on carbohydrate metabolism in the dog. The American journal of physiology. vol 244. issue 6. 1983-07-29. PMID:6134474. |
somatostatin is widely used to inhibit insulin and glucagon release by the pancreas in studies of metabolic regulation in vivo. |
1983-07-29 |
2023-08-12 |
dog |
| G A Praz, P A Halban, C B Wollheim, B Blondel, A J Strauss, A E Renol. Regulation of immunoreactive-insulin release from a rat cell line (RINm5F). The Biochemical journal. vol 210. issue 2. 1983-07-29. PMID:6134520. |
1% of the insulin content of native rat beta-cells, whereas that of immunoreactive glucagon and somatostatin was five to six orders of magnitude less than that of native alpha- or delta-cells respectively. |
1983-07-29 |
2023-08-12 |
rat |