| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
after phloridzin pretreatment to eliminate hyperglycemia in the diabetic dogs, insulin and somatostatin suppressed 51 +/- 8 and 31 +/- 10%/h (ns), respectively. |
1987-01-29 |
2023-08-11 |
Not clear |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
we conclude that insulin and somatostatin suppress glucagon at similar rates irrespective of ambient glucose levels, and that diabetic hyperglucagonemia represents the summation of stimulation by insulin lack minus suppression by the associated hyperglycemia. |
1987-01-29 |
2023-08-11 |
Not clear |
| O Ljungqvist, S Efendic, P Eneroth, B Hamberger, G Nylander, J War. Nutritional status and endocrine response to hemorrhage. Canadian journal of physiology and pharmacology. vol 64. issue 9. 1987-01-22. PMID:2877724. |
in fed rats, insulin and glucagon responses were initially attenuated, while somatostatin increased to an early peak level at 30 min, returning to basal at 90 min. |
1987-01-22 |
2023-08-11 |
rat |
| L Uccioli, G Ghirlanda, P Cotroneo, A Manto, A Solini, A V Grec. Somatostatin plasma levels and biological effects following subcutaneous administration of somatostatin in man. Acta endocrinologica. vol 113. issue 4. 1987-01-22. PMID:2878551. |
following a single subcutaneous injection of 250 micrograms, the somatostatin peak in plasma appeared after 5 min and had only a transient effect on insulin levels. |
1987-01-22 |
2023-08-11 |
human |
| L Uccioli, G Ghirlanda, P Cotroneo, A Manto, A Solini, A V Grec. Somatostatin plasma levels and biological effects following subcutaneous administration of somatostatin in man. Acta endocrinologica. vol 113. issue 4. 1987-01-22. PMID:2878551. |
during continuous administration, somatostatin reached levels able to reduce significantly insulin and glucagon. |
1987-01-22 |
2023-08-11 |
human |
| O D Madsen, L I Larsson, J F Rehfeld, T W Schwartz, A Lernmark, A D Labrecque, D F Steine. Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones. The Journal of cell biology. vol 103. issue 5. 1987-01-21. PMID:2877997. |
whereas most cells stained for the islet hormones, insulin, glucagon, and somatostatin, clustered cells were discovered to contain cholecystokinin (cck). |
1987-01-21 |
2023-08-11 |
rat |
| P R Flatt, K S Tan, C J Bailey, C J Powell, S K Swanston-Flatt, V Mark. Effects of transplantation and resection of a radiation-induced rat insulinoma on glucose homeostasis and the endocrine pancreas. British journal of cancer. vol 54. issue 4. 1987-01-20. PMID:2877684. |
these features were associated with islet atrophy, degenerative changes in pancreatic a and b cells, and decreases in the pancreatic contents of insulin, glucagon and somatostatin. |
1987-01-20 |
2023-08-11 |
rat |
| D González-Bárcena, F Mendoza, A Graef, R Medina, A M Comaru-Schally, A V Schall. Selective inhibitory effect of the analog D5-F-TrP8-D-Cys14 somatostatin on the arginine induced release of insulin, growth hormone and glucagon, in normal human beings. Archivos de investigacion medica. vol 16 Suppl 3. 1987-01-15. PMID:2878649. |
selective inhibitory effect of the analog d5-f-trp8-d-cys14 somatostatin on the arginine induced release of insulin, growth hormone and glucagon, in normal human beings. |
1987-01-15 |
2023-08-11 |
human |
| G Rümenapf, E Hanisch, P O Schwill. Low-dose infusion of somatostatin in man--no effect upon intestinal calcium absorption but a fall in blood insulin. Experimental and clinical endocrinology. vol 87. issue 3. 1987-01-02. PMID:2877894. |
low-dose infusion of somatostatin in man--no effect upon intestinal calcium absorption but a fall in blood insulin. |
1987-01-02 |
2023-08-11 |
human |
| F E Eckhauser, P S Cheung, A I Vinik, W E Strodel, R V Lloyd, N W Thompso. Nonfunctioning malignant neuroendocrine tumors of the pancreas. Surgery. vol 100. issue 6. 1986-12-29. PMID:3024343. |
immunohistochemical staining showed positive reactivity for neuron-specific enolase and chromogranin in all tumors studied but was negative for insulin, glucagon, and somatostatin. |
1986-12-29 |
2023-08-11 |
Not clear |
| M Ehrhart, D Grube, M F Bader, D Aunis, M Gratz. Chromogranin A in the pancreatic islet: cellular and subcellular distribution. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 34. issue 12. 1986-12-24. PMID:2878021. |
at the light microscopic level, cga-like immunoreactivity was found in the same cells that react with antibodies against insulin, glucagon, and somatostatin. |
1986-12-24 |
2023-08-11 |
cattle |
| H Maegawa, M Kobayashi, O Ishibashi, Y Takata, Y Shiget. Effect of diet change on insulin action: difference between muscles and adipocytes. The American journal of physiology. vol 251. issue 5 Pt 1. 1986-12-12. PMID:3535536. |
steady-state plasma glucose (sspg) level was unchanged in hs-fed rats during somatostatin, glucose, and insulin infusion, whereas the sspg level of hf-fed rats was twice as much as that in controls (p less than 0.01). |
1986-12-12 |
2023-08-11 |
rat |
| J Ishizuka, T Toyota, T Ono, M Sasaki, C Yanaihara, N Yanaihar. Inhibitory effects of rimorphin and dynorphin on insulin secretion from the isolated, perfused rat pancreas. The Tohoku journal of experimental medicine. vol 150. issue 1. 1986-12-10. PMID:2877510. |
rimorphin also inhibited glucose-induced insulin secretion even in the cysteamine-treated rat pancreas from which somatostatin had been depleted. |
1986-12-10 |
2023-08-11 |
rat |
| J Ishizuka, T Toyota, T Ono, M Sasaki, C Yanaihara, N Yanaihar. Inhibitory effects of rimorphin and dynorphin on insulin secretion from the isolated, perfused rat pancreas. The Tohoku journal of experimental medicine. vol 150. issue 1. 1986-12-10. PMID:2877510. |
thus, somatostatin does not appear to play a major regulatory role in the insulin secretion in the pancreas. |
1986-12-10 |
2023-08-11 |
rat |
| F Laurent, H Karmann, R Gross, M T Strosser, P Mialh. Glucagon and somatostatin secretion from the perfused splenic bulb of duck pancreas. Acta endocrinologica. vol 113. issue 2. 1986-12-04. PMID:2430419. |
glucagon, somatostatin and insulin secretions were evaluated in a new type of perfusion preparation: the naturally a and d cell rich splenic bulb of duck pancreas. |
1986-12-04 |
2023-08-11 |
Not clear |
| F Laurent, H Karmann, R Gross, M T Strosser, P Mialh. Glucagon and somatostatin secretion from the perfused splenic bulb of duck pancreas. Acta endocrinologica. vol 113. issue 2. 1986-12-04. PMID:2430419. |
however, in the presence of aminoacids, glucagon was inhibited and somatostatin secretion stimulated by glucose (33 mm), independently of insulin (2 ng/ml). |
1986-12-04 |
2023-08-11 |
Not clear |
| G J Bruining, A N Bosschaart, R S Aarsen, S W Lamberts, P J Sauer, E Del Poz. Normalization of glucose homeostasis by a long-acting somatostatin analog SMS 201-995 in a newborn with nesidioblastosis. Acta endocrinologica. Supplementum. vol 279. 1986-11-25. PMID:2877536. |
intravenous infusion of a long acting somatostatin analog, sms 201-995, at a dosage gradually increasing from 2 to 50 micrograms/24 hr, was accompanied by a dramatic fall in circulating insulin levels. |
1986-11-25 |
2023-08-11 |
Not clear |
| T R Ulich, S Y Liao, L Layfield, S Romansky, L Cheng, K J Lewi. Endocrine and tumor differentiation markers in poorly differentiated small-cell carcinoids of the cervix and vagina. Archives of pathology & laboratory medicine. vol 110. issue 11. 1986-11-25. PMID:3022670. |
immunoreactivity for endocrine peptides (serotonin, gastrin, somatostatin, insulin, corticotropin, calcitonin, neurotensin, vasoactive intestinal peptide, and bombesin), cytoskeletal proteins (high and low molecular weight keratins), and tumor differentiation markers (chromogranin, neuron-specific enolase, carcinoembryonic antigen, s100 protein, and grimelius stain) was sought on nine cervical and one vaginal poorly differentiated small-cell carcinoids. |
1986-11-25 |
2023-08-11 |
Not clear |
| M S Rios, I Navascues, J Saban, A Ordoñez, F Sevilla, E Del Poz. Somatostatin analog SMS 201-995 and insulin needs in insulin-dependent diabetic patients studied by means of an artificial pancreas. The Journal of clinical endocrinology and metabolism. vol 63. issue 5. 1986-11-19. PMID:2876005. |
somatostatin analog sms 201-995 and insulin needs in insulin-dependent diabetic patients studied by means of an artificial pancreas. |
1986-11-19 |
2023-08-11 |
Not clear |
| M S Rios, I Navascues, J Saban, A Ordoñez, F Sevilla, E Del Poz. Somatostatin analog SMS 201-995 and insulin needs in insulin-dependent diabetic patients studied by means of an artificial pancreas. The Journal of clinical endocrinology and metabolism. vol 63. issue 5. 1986-11-19. PMID:2876005. |
sms 201-995 is a new somatostatin analog which is 10-60 times more potent and specific than somatostatin as an inhibitor of gh and insulin release. |
1986-11-19 |
2023-08-11 |
Not clear |