| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Ipp, Y Sinai, B Bar-Oz, R Nesher, E Ceras. Somatostatin impairs clearance of exogenous insulin in humans. Diabetes. vol 36. issue 5. 1987-06-01. PMID:2883058. |
to test whether clearance of an exogenously infused hormone is affected, we infused insulin with or without somatostatin in two sets of studies. |
1987-06-01 |
2023-08-11 |
Not clear |
| E Ipp, Y Sinai, B Bar-Oz, R Nesher, E Ceras. Somatostatin impairs clearance of exogenous insulin in humans. Diabetes. vol 36. issue 5. 1987-06-01. PMID:2883058. |
when somatostatin was infused together with insulin, plasma glucose fell to lower levels (41 +/- 4.2 vs. 62 +/- 9.5 mg/dl; p less than .01) and plasma iri rose higher (39 +/- 8.5 vs. 27 +/- 5.9 microu/ml; p less than .01) than when insulin was infused alone. |
1987-06-01 |
2023-08-11 |
Not clear |
| E Ipp, Y Sinai, B Bar-Oz, R Nesher, E Ceras. Somatostatin impairs clearance of exogenous insulin in humans. Diabetes. vol 36. issue 5. 1987-06-01. PMID:2883058. |
c-peptide was equally suppressed by hypoglycemia regardless of whether somatostatin was administered, indicating suppression of endogenous insulin during these studies. |
1987-06-01 |
2023-08-11 |
Not clear |
| E Ipp, Y Sinai, B Bar-Oz, R Nesher, E Ceras. Somatostatin impairs clearance of exogenous insulin in humans. Diabetes. vol 36. issue 5. 1987-06-01. PMID:2883058. |
we conclude that somatostatin infusion impairs the clearance of exogenous insulin. |
1987-06-01 |
2023-08-11 |
Not clear |
| b' C G Ostenson, A Nyl\\xc3\\xa9n, V Grill, M Gutniak, S Efendi\\xc4\\x8. Sulfonylurea-induced inhibition of glucagon secretion from the perfused rat pancreas: evidence for a direct, non-paracrine effect. Diabetologia. vol 29. issue 12. 1987-05-29. PMID:3106122.' |
however, when diabetic rats had been treated with insulin for 6-7 days, glibenclamide suppressed glucagon release at low calcium levels in the absence of stimulated insulin and somatostatin release. |
1987-05-29 |
2023-08-11 |
rat |
| b' C G Ostenson, A Nyl\\xc3\\xa9n, V Grill, M Gutniak, S Efendi\\xc4\\x8. Sulfonylurea-induced inhibition of glucagon secretion from the perfused rat pancreas: evidence for a direct, non-paracrine effect. Diabetologia. vol 29. issue 12. 1987-05-29. PMID:3106122.' |
it is concluded that, at low calcium concentrations, sulfonylureas suppress glucagon secretion by a direct action on the a cell and not through paracrine interactions by insulin and somatostatin. |
1987-05-29 |
2023-08-11 |
rat |
| S A Wolfe-Coote, D F Du Toi. Distribution of cell types of the islets of Langerhans throughout the pancreas of the Chacma baboon. The Anatomical record. vol 217. issue 2. 1987-05-27. PMID:2883914. |
four slides in each batch were immunolabelled consecutively for insulin, glucagon, somatostatin, and pancreatic polypeptide, the fifth acting as one of the range of controls in each batch. |
1987-05-27 |
2023-08-11 |
Not clear |
| J Rahier, S Loozen, R M Goebbels, M Abrahe. The haemochromatotic human pancreas: a quantitative immunohistochemical and ultrastructural study. Diabetologia. vol 30. issue 1. 1987-05-27. PMID:3552822. |
insulin, glucagon, somatostatin and pancreatic polypeptide cells were quantified after immunoperoxidase staining in sections of pancreases obtained from nine control subjects and seven diabetic patients with primary or secondary iron overload. |
1987-05-27 |
2023-08-11 |
human |
| K L Hawkins, B A Summers, F P Kuhajda, C A Smit. Immunocytochemistry of normal pancreatic islets and spontaneous islet cell tumors in dogs. Veterinary pathology. vol 24. issue 2. 1987-05-22. PMID:2883753. |
immunocytochemical studies of the distribution of glucagon, gastrin, insulin, and somatostatin in normal canine pancreatic islets and 20 canine islet cell tumors were done using the peroxidase-anti-peroxidase (pap) technique. |
1987-05-22 |
2023-08-11 |
rabbit |
| K L Hawkins, B A Summers, F P Kuhajda, C A Smit. Immunocytochemistry of normal pancreatic islets and spontaneous islet cell tumors in dogs. Veterinary pathology. vol 24. issue 2. 1987-05-22. PMID:2883753. |
alpha cells (glucagon) were often peripherally located, beta cells (insulin) were centrally located and most numerous, and delta cells (somatostatin) were the least numerous and randomly located. |
1987-05-22 |
2023-08-11 |
rabbit |
| K L Hawkins, B A Summers, F P Kuhajda, C A Smit. Immunocytochemistry of normal pancreatic islets and spontaneous islet cell tumors in dogs. Veterinary pathology. vol 24. issue 2. 1987-05-22. PMID:2883753. |
of the 20 tumors examined, 18 had positive immunoreactivity for insulin, nine for glucagon, 14 for somatostatin, and one for gastrin. |
1987-05-22 |
2023-08-11 |
rabbit |
| K L Hawkins, B A Summers, F P Kuhajda, C A Smit. Immunocytochemistry of normal pancreatic islets and spontaneous islet cell tumors in dogs. Veterinary pathology. vol 24. issue 2. 1987-05-22. PMID:2883753. |
metastatic sites (liver and lymph node) stained for insulin and somatostatin, only. |
1987-05-22 |
2023-08-11 |
rabbit |
| K L Hawkins, B A Summers, F P Kuhajda, C A Smit. Immunocytochemistry of normal pancreatic islets and spontaneous islet cell tumors in dogs. Veterinary pathology. vol 24. issue 2. 1987-05-22. PMID:2883753. |
foci of non-neoplastic islet cell tissue (nesidioblastosis), often located at the pancreatic-mesenteric junction, stained strongly positive for insulin, glucagon, and somatostatin but not for gastrin. |
1987-05-22 |
2023-08-11 |
rabbit |
| R F Nutt, C D Colton, D F Veber, E L Slater, R Saperstei. Somatostatin analogs with improved oral bioavailability. Klinische Wochenschrift. vol 64 Suppl 7. 1987-05-21. PMID:2882053. |
cyclic hexapeptide analogs of somatostatin with insulin, glucagon, and growth hormone (gh) release inhibitory potencies of 50-200 times those of somatostatin have been synthesized. |
1987-05-21 |
2023-08-11 |
Not clear |
| H Koop, H Schwarting, A Knorr-Marin, C Willhardt, T Möser, R Arnol. Influence of chronic omeprazole treatment on gastric endocrine function. Klinische Wochenschrift. vol 65. issue 4. 1987-05-21. PMID:2882060. |
postprandial gastrin release, basal and food-stimulated insulin release, antral somatostatin concentration, and volume densities of antral g and d cells were unaffected. |
1987-05-21 |
2023-08-11 |
human |
| P Ronner, A Scarp. Secretagogues for pancreatic hormone release in the channel catfish (Ictalurus punctatus). General and comparative endocrinology. vol 65. issue 3. 1987-05-18. PMID:2881840. |
we investigated the effect of several potential carbohydrate secretagogues, amino acids, a ketoacid, and potassium chloride on insulin, glucagon, and somatostatin release from the in vitro perfused brockmann body of channel catfish (ictalurus punctatus). |
1987-05-18 |
2023-08-11 |
Not clear |
| P Ronner, A Scarp. Secretagogues for pancreatic hormone release in the channel catfish (Ictalurus punctatus). General and comparative endocrinology. vol 65. issue 3. 1987-05-18. PMID:2881840. |
mannose (15 mm) stimulated the release of insulin and somatostatin. |
1987-05-18 |
2023-08-11 |
Not clear |
| P Ronner, A Scarp. Secretagogues for pancreatic hormone release in the channel catfish (Ictalurus punctatus). General and comparative endocrinology. vol 65. issue 3. 1987-05-18. PMID:2881840. |
a high concentration of potassium (25 meq/liter) induced a pronounced release of insulin and glucagon and a moderate release of somatostatin. |
1987-05-18 |
2023-08-11 |
Not clear |
| P De Feo, G Perriello, M M Ventura, P Brunetti, F Santeusanio, J E Gerich, G B Boll. The pancreatic-adrenocortical-pituitary clamp technique for study of counterregulation in humans. The American journal of physiology. vol 252. issue 4 Pt 1. 1987-05-13. PMID:2882686. |
for this purpose, 24 normal subjects were studied twice: once (control experiments) hypoglycemia was induced by subcutaneous infusion of insulin; and once [pancreatic-adrenocortical-pituitary (pap) clamp technique] the spontaneous responses of plasma glucagon, growth hormone, and cortisol to hypoglycemia were prevented by intravenous somatostatin and oral metyrapone, respectively, and each hormone was infused at variable rates, which reproduced spontaneous changes in their circulating concentrations in the control experiments. |
1987-05-13 |
2023-08-11 |
human |
| W A Bauman, S Meryn, G L Floran. Pancreatic hormones in the nonhibernating and hibernating golden mantled ground squirrel. Comparative biochemistry and physiology. A, Comparative physiology. vol 86. issue 2. 1987-05-12. PMID:2881667. |
the effects of hibernation on pancreatic insulin, glucagon, somatostatin, and pancreatic polypeptide was investigated in the golden mantled ground squirrel (citellus lateralis). |
1987-05-12 |
2023-08-11 |
Not clear |