| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K S Lam, R T Yeung, P W Ho, S K La. Glucose intolerance in thyrotoxicosis roles of insulin, glucagon and somatostatin. Acta endocrinologica. vol 114. issue 2. 1987-03-30. PMID:2881418. |
the responses in plasma glucose, insulin, c-peptide, glucagon and somatostatin to an oral glucose load were studied in 10 thyrotoxic patients and 10 matched euthyroid controls. |
1987-03-30 |
2023-08-11 |
Not clear |
| K Kawai, Y Chiba, Y Okuda, K Yamashit. Hormone release from pancreatic islets perfused from venous side. Diabetes. vol 36. issue 3. 1987-03-24. PMID:2879756. |
basal insulin and glucagon levels and their rate of release in response to 10 mm arginine, 11 mm glucose, 500 pg/ml somatostatin, or 500 pg/ml glucagon were similar under both conditions. |
1987-03-24 |
2023-08-11 |
Not clear |
| J Philippe, D J Drucker, J F Habene. Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway. The Journal of biological chemistry. vol 262. issue 4. 1987-03-23. PMID:2879843. |
we have recently cloned an islet cell line from a rat pancreatic islet cell tumour that simultaneously expresses the glucagon, insulin, somatostatin, and angiotensinogen genes. |
1987-03-23 |
2023-08-11 |
rat |
| J Philippe, D J Drucker, J F Habene. Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway. The Journal of biological chemistry. vol 262. issue 4. 1987-03-23. PMID:2879843. |
the increase was progressive up to 24 h and was specific for glucagon mrna; the insulin and somatostatin mrna levels remained unchanged. |
1987-03-23 |
2023-08-11 |
rat |
| M R Lieber, E E Lack, J R Roberts, M J Merino, K Patterson, C Restrepo, D Solomon, R Chandra, T J Trich. Solid and papillary epithelial neoplasm of the pancreas. An ultrastructural and immunocytochemical study of six cases. The American journal of surgical pathology. vol 11. issue 2. 1987-03-17. PMID:3812876. |
none was positive for alpha-1-antitrypsin, neuron-specific enolase, pancreatic polypeptide, gastrin, glucagon, somatostatin, or insulin. |
1987-03-17 |
2023-08-11 |
Not clear |
| J Philippe, W L Chick, J F Habene. Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:2879852. |
the developmental origin of the four phenotypically distinct hormone-producing islet cells (insulin, glucagon, somatostatin, pancreatic polypeptide) is unclear. |
1987-03-12 |
2023-08-11 |
rat |
| J Philippe, W L Chick, J F Habene. Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:2879852. |
to investigate the potential for phenotypic differentiation of islet cells, we prepared several clonal cell lines from a radiation-induced rat islet tumor and analyzed them for insulin, glucagon, and somatostatin gene expression by cdna hybridization, immunocytochemistry, and radioimmunoassay. |
1987-03-12 |
2023-08-11 |
rat |
| B A Adkins, S R Myers, G K Hendrick, R W Stevenson, P E Williams, A D Cherringto. Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog. The Journal of clinical investigation. vol 79. issue 2. 1987-03-12. PMID:2879854. |
insulin and glucagon were held at constant basal levels using somatostatin and intraportal insulin and glucagon infusions during the control, portal, and peripheral glucose infusion periods (7 +/- 1, 7 +/- 1, 7 +/- 1 microu/ml; 100 +/- 3, 101 +/- 6, 101 +/- 3 pg/ml, respectively). |
1987-03-12 |
2023-08-11 |
dog |
| S J Ashcroft, P Hammonds, D E Harriso. Insulin secretory responses of a clonal cell line of simian virus 40-transformed B cells. Diabetologia. vol 29. issue 10. 1987-03-11. PMID:3026878. |
thus, the response was specific for metabolizable sugars (d-mannose and d-glyceraldehyde stimulated insulin release but l-glucose and d-galactose were ineffective); markedly dependent on extracellular ca2+ concentration; potentiated by forskolin, glucagon, acetylcholine and 12-o-tetradecanoyl phorbol 13-acetate; inhibited by adrenaline or somatostatin; showed a biphasic pattern of release in perifusion experiments, with both phases being potentiated by forskolin. |
1987-03-11 |
2023-08-11 |
Not clear |
| K S Rastogi, S Efendic, L Lickley, N Kovacevic, M Vrani. Elevated somatostatin in pancreatic islets of adrenalectomized dogs. Endocrinology. vol 120. issue 2. 1987-03-04. PMID:2879722. |
to determine whether these hormonal alterations are related to changes in distribution of islet hormones in the pancreas, we examined the concentration and total mass of insulin, glucagon, and somatostatin in the head, body, and tail of the pancreas by immunoassay and immunocytochemistry. |
1987-03-04 |
2023-08-11 |
Not clear |
| K S Rastogi, S Efendic, L Lickley, N Kovacevic, M Vrani. Elevated somatostatin in pancreatic islets of adrenalectomized dogs. Endocrinology. vol 120. issue 2. 1987-03-04. PMID:2879722. |
in normal dogs, single and double immunocytochemical staining showed that, in contrast to some other species, b (insulin) cells are mostly in the central region of islet, whereas a (glucagon) and d (somatostatin) cells are distributed randomly. |
1987-03-04 |
2023-08-11 |
Not clear |
| K S Rastogi, S Efendic, L Lickley, N Kovacevic, M Vrani. Elevated somatostatin in pancreatic islets of adrenalectomized dogs. Endocrinology. vol 120. issue 2. 1987-03-04. PMID:2879722. |
plasma concentration of glucagon increased by 50% in adx i (p less than 0.005) and 70% in adx ii (p less than 0.02), insulin decreased by 39% (p less than 0.005), 23% (ns), respectively, and somatostatin increased by 258% (p less than 0.001) in adx ii. |
1987-03-04 |
2023-08-11 |
Not clear |
| J C Reubi, J Palacio. Somatostatin and Alzheimer's disease: a hypothesis. Journal of neurology. vol 233. issue 6. 1987-03-04. PMID:2879894. |
moreover, some endocrine activities known to be regulated by somatostatin, such as growth hormone, thyroid-stimulating-hormone, somatomedins, as well as insulin and glucose metabolism, also seem to be affected in some patients. |
1987-03-04 |
2023-08-11 |
Not clear |
| F Petraglia, F Facchinetti, G D'Ambrogio, A Volpe, A R Genazzan. Somatostatin and oxytocin infusion inhibits the rise of plasma beta-endorphin, beta-lipotrophin and cortisol induced by insulin hypoglycaemia. Clinical endocrinology. vol 24. issue 6. 1987-02-05. PMID:2878746. |
somatostatin and oxytocin infusion inhibits the rise of plasma beta-endorphin, beta-lipotrophin and cortisol induced by insulin hypoglycaemia. |
1987-02-05 |
2023-08-11 |
human |
| J Takemura, Y N Kwok, J C Brow. Comparison of the effect of somatostatin and an analogue, SMS 201-995, on gastrin and insulin secretion from isolated perfused rat stomach and pancreas. The American journal of medicine. vol 81. issue 6B. 1987-02-04. PMID:2879449. |
comparison of the effect of somatostatin and an analogue, sms 201-995, on gastrin and insulin secretion from isolated perfused rat stomach and pancreas. |
1987-02-04 |
2023-08-11 |
rat |
| J Takemura, Y N Kwok, J C Brow. Comparison of the effect of somatostatin and an analogue, SMS 201-995, on gastrin and insulin secretion from isolated perfused rat stomach and pancreas. The American journal of medicine. vol 81. issue 6B. 1987-02-04. PMID:2879449. |
the effects of a somatostatin analogue, sms 201-995, and somatostatin-14 on gastrin and insulin release from the isolated perfused rat stomach and pancreas were studied. |
1987-02-04 |
2023-08-11 |
rat |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. |
1987-01-29 |
2023-08-11 |
Not clear |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
the glucagon-suppressing activity of insulin and somatostatin were compared at high and low glucose concentrations. |
1987-01-29 |
2023-08-11 |
Not clear |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
in normal dogs made hyperglucagonemic by phloridzin pretreatment, insulin and somatostatin suppressed glucagon at rates of 47 +/- 8 and 35 +/- 8%/h (ns), respectively, despite profound hypoglycemia. |
1987-01-29 |
2023-08-11 |
Not clear |
| A Starke, T Imamura, R H Unge. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. The Journal of clinical investigation. vol 79. issue 1. 1987-01-29. PMID:2878938. |
in severely hyperglycemic alloxan-diabetic dogs, insulin and somatostatin suppressed glucagon at rates of 48 +/- 13 and 54 +/- 6%/h, respectively, not different from the nondiabetic dogs. |
1987-01-29 |
2023-08-11 |
Not clear |