| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
in order to study the long-term influence of glucose on islet cell functions, biosynthesis of (pro)insulin (3h-leucine incorporation during 3h-incubation both at 50 and 300 mg/dl of glucose), release of insulin and somatostatin and degradation of intra-insular insulin were measured in isolated rat islets, cultured for 3 days at 50, 150 and 300 mg/dl glucose. |
1987-07-24 |
2023-08-11 |
rat |
| A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
during the 3 days of culture, the percentual differences in hormone release at 50, 150 and 300 mg/dl of glucose were, altogether, also higher for somatostatin than for insulin. |
1987-07-24 |
2023-08-11 |
rat |
| A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
at low glucose concentration the pre-synthesized insulin (which was not needed then physiologically) was again degraded within the islet cells; at higher concentrations of glucose, increased stimulation of the b-cells seemed to be modified by the--paracrine--action of somatostatin. |
1987-07-24 |
2023-08-11 |
rat |
| S Knuhtsen, J J Holst, T W Schwartz, S L Jensen, O V Nielse. The effect of gastrin-releasing peptide on the endocrine pancreas. Regulatory peptides. vol 17. issue 5. 1987-07-24. PMID:2885899. |
grp-(1-27) stimulated insulin and pancreatic polypeptide secretion and inhibited somatostatin secretion in a dose-dependent manner. |
1987-07-24 |
2023-08-11 |
Not clear |
| S Knuhtsen, J J Holst, T W Schwartz, S L Jensen, O V Nielse. The effect of gastrin-releasing peptide on the endocrine pancreas. Regulatory peptides. vol 17. issue 5. 1987-07-24. PMID:2885899. |
the effect of grp-(1-27) on insulin secretion was enhanced with increasing perfusate glucose levels, whereas the effects upon somatostatin and pancreatic polypeptide secretion were independent of perfusate glucose levels. |
1987-07-24 |
2023-08-11 |
Not clear |
| H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
the animals received either a 420 min infusion of (1) somatostatin alone (0.3 microgram x kg-1 x min-1), (2) somatostatin with insulin replacement (100 microu x kg-1 x min-1) or (3) glucagon (6 ng x kg-1 x min-1) together with somatostatin and transient insulin replacement. |
1987-07-17 |
2023-08-11 |
Not clear |
| H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
when somatostatin was given alone, plasma glucagon (p less than 0.004) and insulin (p less than 0.0001) were suppressed. |
1987-07-17 |
2023-08-11 |
Not clear |
| H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
when insulin replacement was given during somatostatin infusion to correct for the small somatostatin-induced insulin suppression, there were similar changes in plasma glucagon, glucose concentrations and glucose kinetics as seen during the infusion of somatostatin alone. |
1987-07-17 |
2023-08-11 |
Not clear |
| C Foltzer, S Harvey, P Mialh. Pancreatic somatostatin, glucagon and insulin during post-hatch growth in the duck (Anas platyrhynchos). The Journal of endocrinology. vol 113. issue 1. 1987-07-13. PMID:2884271. |
pancreatic somatostatin, glucagon and insulin during post-hatch growth in the duck (anas platyrhynchos). |
1987-07-13 |
2023-08-11 |
Not clear |
| G A Werther, M A Sperling, S Joffe, R F Murph. The regulation of basal pancreatic polypeptide levels in dogs. Regulatory peptides. vol 17. issue 4. 1987-07-13. PMID:2884699. |
somatostatin infusion (0.2 microgram/kg/min) with insulin and glucagon replacement, led to a similar sustained fall in pp. |
1987-07-13 |
2023-08-11 |
Not clear |
| K Gyr, C Beglinger, E Köhler, U Trautzl, U Keller, S R Bloo. Circulating somatostatin. Physiological regulator of pancreatic function? The Journal of clinical investigation. vol 79. issue 6. 1987-07-10. PMID:2884233. |
infusion of somatostatin inhibited hormone-induced exocrine pancreatic secretion and suppressed cerulein-stimulated pancreatic polypeptide (pp) secretion, but did not significantly change arginine-stimulated insulin and glucagon release at mean plasma somatostatin concentrations within the range seen after a meal. |
1987-07-10 |
2023-08-11 |
human |
| K Gyr, C Beglinger, E Köhler, U Trautzl, U Keller, S R Bloo. Circulating somatostatin. Physiological regulator of pancreatic function? The Journal of clinical investigation. vol 79. issue 6. 1987-07-10. PMID:2884233. |
on the other hand, basal and arginine-stimulated glucagon and insulin secretions were not significantly affected by these plasma concentrations of intravenous somatostatin suggesting that the exocrine pancreas might be more sensitive to somatostatin than the islet cells. |
1987-07-10 |
2023-08-11 |
human |
| R Horikawa, K Takano, N Hizuka, K Asakawa, T Shibasaki, A Masuda, K Shizum. Effect of a single administration of somatostatin analogue (SMS 201-995) on GH, TSH and insulin secretion in patients with acromegaly. Endocrinologia japonica. vol 33. issue 6. 1987-06-26. PMID:2884093. |
effect of a single administration of somatostatin analogue (sms 201-995) on gh, tsh and insulin secretion in patients with acromegaly. |
1987-06-26 |
2023-08-11 |
Not clear |
| D R Matthews, K Hermansen, A A Connolly, D Gray, O Schmitz, A Clark, H Orskov, R C Turne. Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:2883001. |
greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. |
1987-06-25 |
2023-08-11 |
dog |
| D R Matthews, K Hermansen, A A Connolly, D Gray, O Schmitz, A Clark, H Orskov, R C Turne. Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:2883001. |
in addition, somatostatin was secreted from the in vitro pancreas in pulses in phase with insulin (cross-correlation p less than 0.0001). |
1987-06-25 |
2023-08-11 |
dog |
| B E Rosendale, D B Jarrett, A G Robinso. Identification of a corticotropin-releasing factor-binding protein in the plasma membrane of AtT-20 mouse pituitary tumor cells and its regulation by dexamethasone. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:3032586. |
similar concentrations (10(-7) m) of trh, gnrh, insulin, [arg8]vasopressin, somatostatin, and acth did not inhibit [125i]iodo-tyr0crf binding to the plasma membranes. |
1987-06-25 |
2023-08-11 |
mouse |
| B Skogseid, K Oberg, L Benson, P G Lindgren, L E Lörelius, G Lundquist, L Wide, E Wilande. A standardized meal stimulation test of the endocrine pancreas for early detection of pancreatic endocrine tumors in multiple endocrine neoplasia type 1 syndrome: five years experience. The Journal of clinical endocrinology and metabolism. vol 64. issue 6. 1987-06-23. PMID:2883195. |
serum pancreatic polypeptide (pp), gastrin, and insulin as well as plasma glucagon and somatostatin concentrations were determined before and during the test meal. |
1987-06-23 |
2023-08-11 |
human |
| G N Hansen, B L Hansen, P N Jørgense. Insulin-, glucagon- and somatostatin-like immunoreactivity in the endocrine pancreas of the lungfish, Neoceratodus forsteri. Cell and tissue research. vol 248. issue 1. 1987-06-15. PMID:2882854. |
glucagon and somatostatin cells are distributed peripherally around the central mass of the insulin cells. |
1987-06-15 |
2023-08-11 |
Not clear |
| G S Spencer, D J Hill, G J Garssen, J P William. Somatostatin inhibits insulin-stimulated amino acid uptake into cultured rat myoblasts. Acta endocrinologica. vol 114. issue 4. 1987-06-10. PMID:2883796. |
the effects of somatostatin on the acute metabolic actions of insulin on newborn rat myoblasts in culture has been examined during monolayer culture. |
1987-06-10 |
2023-08-11 |
rat |
| G S Spencer, D J Hill, G J Garssen, J P William. Somatostatin inhibits insulin-stimulated amino acid uptake into cultured rat myoblasts. Acta endocrinologica. vol 114. issue 4. 1987-06-10. PMID:2883796. |
the inhibitory effect of somatostatin was seen at all effective concentrations of insulin used (0.3-1 u/l). |
1987-06-10 |
2023-08-11 |
rat |