Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E Solcia, L Usellini, R Buffa, G Rindi, L Villani, C Zampatti, E Silin. Endocrine cells producing regulatory peptides. Experientia. vol 43. issue 7. 1987-08-20. PMID:3297770. |
gastrin, xenopsin, cholecystokinin (cck), somatostatin, motilin, secretin, gip (gastric inhibitory polypeptide), neurotensin, glicentin/glucagon-37 and pyy (peptide tyrosine tyrosine) are the main products of gastrointestinal endocrine cells; glucagon, crf (corticotropin releasing factor), somatostatin, pp (pancreatic polypeptide) and grf (growth hormone releasing factor), in addition to insulin, are produced in pancreatic islet cells; bombesin-related peptides are the main markers of pulmonary endocrine cells; calcitonin and cgrp (calcitonin gene-related peptide) occur in thyroid and extrathyroid c cells; acth and endorphins in anterior and intermediate lobe pituitary cells, alpha-msh and clip (corticotropin-like intermediate lobe peptide) in intermediate lobe cells; met- and leu-enkephalins and related peptides in adrenal medullary and paraganglionic cells as well as in some gut (enterochromaffin) cells; npy (neuropeptide y) in adrenaline-type adrenal medullary cells, etc.. |
1987-08-20 |
2023-08-11 |
Not clear |
G Paolisso, D Giugliano, A J Scheen, P Franchimont, F D'Onofrio, P J Lefèbvr. Primary role of glucagon release in the effect of beta-endorphin on glucose homeostasis in normal man. Acta endocrinologica. vol 115. issue 2. 1987-08-19. PMID:2885994. |
the influence of beta-endorphin per se on glucose homeostasis was studied in 7 other subjects using the euglycaemic clamp technique in which the endocrine pancreatic function was fixed at its basal level with somatostatin together with replacement of basal insulin and glucagon by the exogenous infusion of these hormones. |
1987-08-19 |
2023-08-11 |
human |
T Kobayashi, S Sawano, T Itoh, K Kosak. Plasma immunoreactive somatostatin response to arginine after glycemic control with continuous subcutaneous insulin infusion in type I diabetics. Diabetes care. vol 10. issue 3. 1987-08-11. PMID:2885161. |
plasma immunoreactive somatostatin response to arginine after glycemic control with continuous subcutaneous insulin infusion in type i diabetics. |
1987-08-11 |
2023-08-11 |
Not clear |
S A Wolfe-Coote, D F du Toi. Morphology and endocrine production of cells in the islets of Langerhans of the Chacma baboon. The Anatomical record. vol 218. issue 1. 1987-08-05. PMID:2886075. |
insulin glucagon, somatostatin and pancreatic polypeptide (pp) producing cells were described. |
1987-08-05 |
2023-08-11 |
Not clear |
R A Silvestre, P Miralles, L Monge, P Moreno, M L Villanueva, J Marc. Effects of galanin on hormone secretion from the in situ perfused rat pancreas and on glucose production in rat hepatocytes in vitro. Endocrinology. vol 121. issue 1. 1987-07-27. PMID:2439313. |
in this work, we have studied the effect of galanin (a 200 ng bolus followed by constant infusion at a concentration of 16.8 ng/ml for 22-24 min) on insulin, glucagon, and somatostatin secretion in the perfused rat pancreas. |
1987-07-27 |
2023-08-11 |
rat |
A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
in order to study the long-term influence of glucose on islet cell functions, biosynthesis of (pro)insulin (3h-leucine incorporation during 3h-incubation both at 50 and 300 mg/dl of glucose), release of insulin and somatostatin and degradation of intra-insular insulin were measured in isolated rat islets, cultured for 3 days at 50, 150 and 300 mg/dl glucose. |
1987-07-24 |
2023-08-11 |
rat |
A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
during the 3 days of culture, the percentual differences in hormone release at 50, 150 and 300 mg/dl of glucose were, altogether, also higher for somatostatin than for insulin. |
1987-07-24 |
2023-08-11 |
rat |
A K Chatterjee, H Schat. Regulation of biosynthesis, release and degradation of insulin in cultured rat islets. Experimental and clinical endocrinology. vol 89. issue 1. 1987-07-24. PMID:2885207. |
at low glucose concentration the pre-synthesized insulin (which was not needed then physiologically) was again degraded within the islet cells; at higher concentrations of glucose, increased stimulation of the b-cells seemed to be modified by the--paracrine--action of somatostatin. |
1987-07-24 |
2023-08-11 |
rat |
S Knuhtsen, J J Holst, T W Schwartz, S L Jensen, O V Nielse. The effect of gastrin-releasing peptide on the endocrine pancreas. Regulatory peptides. vol 17. issue 5. 1987-07-24. PMID:2885899. |
grp-(1-27) stimulated insulin and pancreatic polypeptide secretion and inhibited somatostatin secretion in a dose-dependent manner. |
1987-07-24 |
2023-08-11 |
Not clear |
S Knuhtsen, J J Holst, T W Schwartz, S L Jensen, O V Nielse. The effect of gastrin-releasing peptide on the endocrine pancreas. Regulatory peptides. vol 17. issue 5. 1987-07-24. PMID:2885899. |
the effect of grp-(1-27) on insulin secretion was enhanced with increasing perfusate glucose levels, whereas the effects upon somatostatin and pancreatic polypeptide secretion were independent of perfusate glucose levels. |
1987-07-24 |
2023-08-11 |
Not clear |
H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
the animals received either a 420 min infusion of (1) somatostatin alone (0.3 microgram x kg-1 x min-1), (2) somatostatin with insulin replacement (100 microu x kg-1 x min-1) or (3) glucagon (6 ng x kg-1 x min-1) together with somatostatin and transient insulin replacement. |
1987-07-17 |
2023-08-11 |
Not clear |
H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
when somatostatin was given alone, plasma glucagon (p less than 0.004) and insulin (p less than 0.0001) were suppressed. |
1987-07-17 |
2023-08-11 |
Not clear |
H L Lickley, F W Kemmer, K M el-Tayeb, M Vrani. Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs. Diabetologia. vol 30. issue 3. 1987-07-17. PMID:2884159. |
when insulin replacement was given during somatostatin infusion to correct for the small somatostatin-induced insulin suppression, there were similar changes in plasma glucagon, glucose concentrations and glucose kinetics as seen during the infusion of somatostatin alone. |
1987-07-17 |
2023-08-11 |
Not clear |
C Foltzer, S Harvey, P Mialh. Pancreatic somatostatin, glucagon and insulin during post-hatch growth in the duck (Anas platyrhynchos). The Journal of endocrinology. vol 113. issue 1. 1987-07-13. PMID:2884271. |
pancreatic somatostatin, glucagon and insulin during post-hatch growth in the duck (anas platyrhynchos). |
1987-07-13 |
2023-08-11 |
Not clear |
G A Werther, M A Sperling, S Joffe, R F Murph. The regulation of basal pancreatic polypeptide levels in dogs. Regulatory peptides. vol 17. issue 4. 1987-07-13. PMID:2884699. |
somatostatin infusion (0.2 microgram/kg/min) with insulin and glucagon replacement, led to a similar sustained fall in pp. |
1987-07-13 |
2023-08-11 |
Not clear |
K Gyr, C Beglinger, E Köhler, U Trautzl, U Keller, S R Bloo. Circulating somatostatin. Physiological regulator of pancreatic function? The Journal of clinical investigation. vol 79. issue 6. 1987-07-10. PMID:2884233. |
infusion of somatostatin inhibited hormone-induced exocrine pancreatic secretion and suppressed cerulein-stimulated pancreatic polypeptide (pp) secretion, but did not significantly change arginine-stimulated insulin and glucagon release at mean plasma somatostatin concentrations within the range seen after a meal. |
1987-07-10 |
2023-08-11 |
human |
K Gyr, C Beglinger, E Köhler, U Trautzl, U Keller, S R Bloo. Circulating somatostatin. Physiological regulator of pancreatic function? The Journal of clinical investigation. vol 79. issue 6. 1987-07-10. PMID:2884233. |
on the other hand, basal and arginine-stimulated glucagon and insulin secretions were not significantly affected by these plasma concentrations of intravenous somatostatin suggesting that the exocrine pancreas might be more sensitive to somatostatin than the islet cells. |
1987-07-10 |
2023-08-11 |
human |
R Horikawa, K Takano, N Hizuka, K Asakawa, T Shibasaki, A Masuda, K Shizum. Effect of a single administration of somatostatin analogue (SMS 201-995) on GH, TSH and insulin secretion in patients with acromegaly. Endocrinologia japonica. vol 33. issue 6. 1987-06-26. PMID:2884093. |
effect of a single administration of somatostatin analogue (sms 201-995) on gh, tsh and insulin secretion in patients with acromegaly. |
1987-06-26 |
2023-08-11 |
Not clear |
D R Matthews, K Hermansen, A A Connolly, D Gray, O Schmitz, A Clark, H Orskov, R C Turne. Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:2883001. |
greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. |
1987-06-25 |
2023-08-11 |
dog |
D R Matthews, K Hermansen, A A Connolly, D Gray, O Schmitz, A Clark, H Orskov, R C Turne. Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:2883001. |
in addition, somatostatin was secreted from the in vitro pancreas in pulses in phase with insulin (cross-correlation p less than 0.0001). |
1987-06-25 |
2023-08-11 |
dog |